ONTOLOGY REPORT - ANNOTATIONS

Term:corticotropin-releasing hormone signaling pathway
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Accession:PW:0000493 term browser browse the term
Definition:Corticotropin-releasing hormone is secreted by the hypothalamus in response to stress or fear and signaling through its receptors stimulates secretion of corticotropic (adrenocorticotropic, ACTH) hormone by the anterior pituitary. ACTH is one of the cleavage products of pro-opiomelanocortin (POMC).
Synonyms:related_synonym: CRH
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corticotropin-releasing hormone signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adrbk2 adrenergic, beta, receptor kinase 2 ISS RGD:5147387 RGD
G Arrb1 arrestin, beta 1 GBrowse link ISS 1 156,871,564 156,937,540 RGD:5147673 RGD
G Arrb2 arrestin, beta 2 GBrowse link ISS 10 57,244,071 57,284,166 RGD:5147673 RGD
G Crh corticotropin releasing hormone GBrowse link ISS 2 104,764,023 104,765,887 RGD:5147387 RGD
G Crh corticotropin releasing hormone GBrowse link TAS 2 104,764,023 104,765,887 RGD:1358326 RGD
G Crhbp corticotropin releasing hormone binding protein GBrowse link ISS 2 25,801,371 25,813,457 RGD:5147387 RGD
G Crhr1 corticotropin releasing hormone receptor 1 GBrowse link TAS 10 93,312,405 93,354,229 RGD:1358326 RGD
G Crhr1 corticotropin releasing hormone receptor 1 GBrowse link ISS 10 93,312,405 93,354,229 RGD:5147387 RGD
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link ISS 4 83,839,822 83,867,017 RGD:5147387 RGD
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link TAS 4 83,839,822 83,867,017 RGD:1358326 RGD
G Gnas GNAS complex locus GBrowse link ISS 3 165,213,399 165,214,551 RGD:5147387 RGD
G Grk6 G protein-coupled receptor kinase 6 GBrowse link ISS 17 15,220,992 15,236,617 RGD:5147387 RGD
G Ucn urocortin GBrowse link ISS 6 25,216,788 25,217,618 RGD:5147387 RGD
G Ucn2 urocortin 2 GBrowse link ISS 8 114,003,817 114,005,366 RGD:5147387 RGD
G Ucn3 urocortin 3 GBrowse link ISS 17 77,482,852 77,488,471 RGD:5147387 RGD
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  Pathway Ontology 17140
    signaling pathway 7465
      hormone signaling pathway 1128
        peptide and protein hormone signaling pathway 852
          corticotropin-releasing hormone signaling pathway 15
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