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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:pentose phosphate pathway
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Accession:PW:0000045 term browser browse the term
Definition:Those metabolic reactions involved in the generation of reducing equivalents and five carbon (pentose) sugars. The oxidative phase is irreversible; the non-oxidative is reversible.
Synonyms:related_synonym: hexose monophosphate pathway (shunt);   pentose phosphate shunt;   phosphogluconate pathway
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pentose phosphate pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldoart2 aldolase 1 A retrogene 2 ISO SMPDB SMP:00031 NCBI chr 6:72,939,821...72,941,511
Ensembl chr 6:72,939,788...72,941,709 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEA KEGG rno:00030 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C IEA KEGG rno:00030 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Dera deoxyribose-phosphate aldolase ISO SMPDB SMP:00031 NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 IEA KEGG rno:00030 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gpi glucose-6-phosphate isomerase IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) IEA KEGG rno:00030 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
G Pfkl phosphofructokinase, liver type IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315 		JBrowse link
G Pfkm phosphofructokinase, muscle IEA KEGG rno:00030 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192 		JBrowse link
G Pfkp phosphofructokinase, platelet IEA KEGG rno:00030 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pgd phosphogluconate dehydrogenase IDA
ISO		 SMPDB
RGD		 PMID:2843500 SMP:00031, RGD:1599574 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgls 6-phosphogluconolactonase IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803 		JBrowse link
G Pgm1 phosphoglucomutase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 IEA KEGG rno:00030 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187 		JBrowse link
G Prps1l1 phosphoribosyl pyrophosphate synthetase 1-like 1 IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 6:51,684,960...51,686,650
Ensembl chr 6:51,684,948...51,687,291 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 IEA KEGG rno:00030 NCBI chr  X:26,975,915...27,013,184
Ensembl chr  X:26,976,061...27,013,181 		JBrowse link
G Rbks ribokinase IEA
ISO		 KEGG
SMPDB		 SMP:00031 rno:00030 NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290 		JBrowse link
G Rgn regucalcin IEA KEGG rno:00030 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase IDA
ISO
IEA		 SMPDB
KEGG
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591 		JBrowse link
G Rpia ribose 5-phosphate isomerase A IDA
ISO
IEA		 SMPDB
KEGG
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355 		JBrowse link
G Taldo1 transaldolase 1 IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tkt transketolase IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:2843500 SMP:00031 rno:00030, RGD:1599574 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
G Tktl1 transketolase-like 1 IEA KEGG rno:00030 NCBI chr  X:151,954,261...151,987,208
Ensembl chr  X:151,954,175...151,987,208 		JBrowse link
G Tktl2 transketolase-like 2 IEA KEGG rno:00030 NCBI chr16:23,202,460...23,209,741
Ensembl chr16:23,202,453...23,209,742 		JBrowse link
pentose phosphate pathway - non-oxidative phase term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpe ribulose-5-phosphate-3-epimerase TAS RGD PMID:12721358 RGD:1641814 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591 		JBrowse link
G Rpia ribose 5-phosphate isomerase A TAS RGD PMID:12721358 RGD:1641814 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355 		JBrowse link
G Taldo1 transaldolase 1 IDA
TAS		 RGD PMID:8477719 PMID:12721358 RGD:1641803, RGD:1641814 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tkt transketolase TAS
IDA		 RGD PMID:9924800 PMID:16116031 PMID:12721358 RGD:1641798, RGD:1580394, RGD:1641814 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
pentose phosphate pathway - oxidative phase term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase ISO RGD PMID:15466941 RGD:1625539 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Pgd phosphogluconate dehydrogenase ISO RGD PMID:15466941 RGD:1625539 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Pgls 6-phosphogluconolactonase IDA RGD PMID:971315 RGD:2311501 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      carbohydrate metabolic pathway 526
        glucose metabolic pathway 153
          pentose phosphate pathway 27
            pentose phosphate pathway - non-oxidative phase 4
            pentose phosphate pathway - oxidative phase 3
paths to the root