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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:collagenase-solubilized rat glomerular basement membrane
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Accession:XCO:0000387 term browser browse the term
Definition:A condition in which the main influencing factor is a relatively undefined mix of macromolecules such as glycoproteins, proteoglycans, and fragmented collagens, derived from the basement membrane of renal glomeruli from rats (i.e., members of the species Rattus norvegicus) via treatment with collagenase, an enzyme that catalyzes the hydrolysis of peptide bonds in triple helical regions of collagen, one of the major components of basement membranes. A basement membrane is an organised multi-molecular extracellular matrix which is characteristically found under epithelial and endothelial cells.
Synonyms:related_synonym: collagenase-solubilized rat GBM


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collagenase-solubilized rat glomerular basement membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Glom27 Glomerulus QTL 27 IDA RGD PMID:22445570 RGD:7207870 NCBI chr13:20,605,871...101,339,738 JBrowse link
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  experimental condition 2376
    disease-inducing agent 223
      glomerulonephritis-inducing agent 1
        collagenase-solubilized glomerular basement membrane 1
          collagenase-solubilized rat glomerular basement membrane 1
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