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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:hexamethonium
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Accession:XCO:0000320 term browser browse the term
Definition:Either of two compounds (C12H30Br2N2 or C12H30Cl2N2) used in the treatment of hypertension. Hexamethonium is a depolarising ganglionic blocker, a nicotinic acetylcholine receptor antagonist that acts in autonomic ganglia by binding in or on the receptor but not the acetylcholine binding site itself.
Synonyms:exact_synonym: Benzohexamethonium;   hexamethone;   hexathonide
 xref: CHEBI:5700;   CID:3604;   MESH:D018738


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hexamethonium term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q BpQTLcluster9 Blood pressure QTL cluster 9 IDA RGD PMID:10779487 RGD:68932 NCBI chr10:42,323,132...87,323,132 JBrowse link

Related Phenotype Data for Term "hexamethonium" (XCO:0000320)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  experimental condition 2376
    chemical 712
      chemical with specified function 517
        inhibitor 40
          receptor antagonist 31
            cholinergic antagonist 1
              nicotinic antagonist 1
                hexamethonium 1
                  hexamethonium bromide 0
                  hexamethonium chloride 0
paths to the root