ONTOLOGY REPORT - ANNOTATIONS
Term: Acute Lung Injury
Accession: RDO:0007706
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Definition: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
Synonyms: exact_synonym: Acute Lung Injuries
primary_id: MESH:D055371
Acute Lung Injury
G
Adipoq
adiponectin, C1Q and collagen domain containing
ISS
11
79,908,291
79,911,065
RGD:5686380
RGD
G
Adra2a
adrenoceptor alpha 2A
IEP
RGD:6480481
RGD
G
Alb
albumin
IED
14
19,126,935
19,142,214
RGD:6483494
RGD
G
Alox15
arachidonate 15-lipoxygenase
ISS
10
57,185,939
57,194,388
RGD:5509626
RGD
G
Ccl2
chemokine (C-C motif) ligand 2
IEP
10
70,256,263
70,258,061
RGD:6480432
RGD
G
Ccl4
chemokine (C-C motif) ligand 4
ISS
10
71,759,643
71,761,115
RGD:5683874
RGD
G
Ccl4
chemokine (C-C motif) ligand 4
IPM
10
71,759,643
71,761,115
RGD:68880
RGD
G
Ccl4
chemokine (C-C motif) ligand 4
IEP
10
71,759,643
71,761,115
RGD:6480432
RGD
G
Ccr1
chemokine (C-C motif) receptor 1
ISS
8
128,693,658
128,699,213
RGD:5688151
RGD
G
Cd36
CD36 molecule (thrombospondin receptor)
ISS
4
13,471,878
13,525,620
RGD:6893505
RGD
G
Cxcl1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
ISS
14
18,690,339
18,692,118
RGD:5135253
RGD
G
Cxcl2
chemokine (C-X-C motif) ligand 2
ISS
14
18,677,129
18,679,175
RGD:5135247
RGD
G
Cxcl2
chemokine (C-X-C motif) ligand 2
ISS
14
18,677,129
18,679,175
RGD:5135253
RGD
G
Cxcl2
chemokine (C-X-C motif) ligand 2
IEP
14
18,677,129
18,679,175
RGD:5147925
RGD
G
Cxcl5
chemokine (C-X-C motif) ligand 5
ISS
14
18,825,357
18,826,269
RGD:5135247
RGD
G
Cxcl5
chemokine (C-X-C motif) ligand 5
IPM
14
18,825,357
18,826,269
RGD:5135256
RGD
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
ISS
8
61,462,207
61,468,237
RGD:5135235
RGD
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
IEP
8
61,462,207
61,468,237
RGD:5147744
RGD
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
IEP
1
81,266,828
81,290,471
RGD:5147744
RGD
G
Ephx2
epoxide hydrolase 2, cytoplasmic
IED
15
45,497,660
45,556,101
RGD:5688354
RGD
G
Fcgr1a
Fc fragment of IgG, high affinity Ia, receptor (CD64)
IPM
2
191,095,026
191,103,942
RGD:5147925
RGD
G
Fcgr2a
Fc fragment of IgG, low affinity IIa, receptor
IPM
13
86,898,651
86,911,743
RGD:5147925
RGD
G
Flt1
FMS-related tyrosine kinase 1
IPM
12
7,858,092
8,035,966
RGD:5684427
RGD
G
Gzmb
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
ISS
15
35,195,075
35,198,506
RGD:5135517
RGD
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
ISS
2
27,127,504
27,149,580
RGD:5508470
RGD
G
Ifng
interferon gamma
IEP
7
57,621,756
57,625,792
RGD:6480432
RGD
G
Il1b
interleukin 1 beta
IED
3
116,964,422
116,970,867
RGD:7204498
RGD
G
Il1b
interleukin 1 beta
IEP
3
116,964,422
116,970,867
RGD:4143193
RGD
G
Il1b
interleukin 1 beta
ISS
3
116,964,422
116,970,867
RGD:4142807
RGD
G
Il1b
interleukin 1 beta
IEP
3
116,964,422
116,970,867
RGD:4142531
RGD
G
Il1b
interleukin 1 beta
IEP
3
116,964,422
116,970,867
RGD:6480432
RGD
G
Il1rl1
interleukin 1 receptor-like 1
ISS
9
39,577,879
39,624,781
RGD:5144222
RGD
G
Il2
interleukin 2
IEP
2
123,655,005
123,659,709
RGD:6480432
RGD
G
Il22
interleukin 22
ISS
7
57,517,321
57,521,786
RGD:4888524
RGD
G
Itgb2
integrin, beta 2
IPM
20
11,446,521
11,485,009
RGD:6482199
RGD
G
Kdr
kinase insert domain receptor
IEP
RGD:5684427
RGD
G
Mpo
myeloperoxidase
ISS
10
76,085,872
76,097,012
RGD:6909173
RGD
G
Ngf
nerve growth factor (beta polypeptide)
ISS
2
197,621,726
197,632,960
RGD:5144065
RGD
G
Nos2
nitric oxide synthase 2, inducible
IPM
10
65,036,884
65,072,453
RGD:5147744
RGD
G
P2ry12
purinergic receptor P2Y, G-protein coupled, 12
IPM
2
148,611,035
148,613,985
RGD:6480522
RGD
G
Pecam1
platelet/endothelial cell adhesion molecule 1
IED
10
96,056,220
96,057,232
RGD:6483494
RGD
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
ISS
6
50,441,892
50,476,931
RGD:6482677
RGD
G
Pla2g2a
phospholipase A2, group IIA (platelets, synovial fluid)
Severity
IEP
5
157,654,786
157,657,360
RGD:6482722
RGD
G
Plau
plasminogen activator, urokinase
IED
15
3,680,072
3,686,232
RGD:5147760
RGD
G
Plau
plasminogen activator, urokinase
Treatment
IED
15
3,680,072
3,686,232
RGD:7241552
RGD
G
Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
ISS
2
54,327,821
54,360,462
RGD:6484539
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
IEP
13
64,427,288
64,432,978
RGD:5135496
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISS
13
64,427,288
64,432,978
RGD:5135287
RGD
G
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
IEP
1
211,758,103
211,761,651
RGD:5143982
RGD
G
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
ISS
1
211,758,103
211,761,651
RGD:5144142
RGD
G
Tac1
tachykinin, precursor 1
ISS
4
32,649,666
32,657,632
RGD:5147812
RGD
G
Tacr1
tachykinin receptor 1
ISS
4
116,610,595
116,780,394
RGD:5147819
RGD
G
Thbd
thrombomodulin
ISS
3
137,158,955
137,162,607
RGD:5131887
RGD
G
Thbd
thrombomodulin
ISS
3
137,158,955
137,162,607
RGD:5685372
RGD
G
Tlr4
toll-like receptor 4
IEP
5
83,564,100
83,577,735
RGD:5135496
RGD
G
Tnf
tumor necrosis factor
IEP
20
3,661,000
3,663,618
RGD:6480432
RGD
G
Tnf
tumor necrosis factor
IEP
20
3,661,000
3,663,618
RGD:5147925
RGD
G
Vegfa
vascular endothelial growth factor A
IEP
9
10,520,730
10,536,071
RGD:5684427
RGD
G
Vip
vasoactive intestinal peptide
IED
1
36,361,513
36,369,594
RGD:4145303
RGD
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