ONTOLOGY REPORT - ANNOTATIONS
| Term: | Pulmonary Disease, Chronic Obstructive |
|
| Accession: | RDO:0007473
|
browse the term
|
| Definition: | A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA. |
| Synonyms: | exact_synonym: | COAD; COPD; COPD, SEVERE EARLY-ONSET; Chronic Airflow Obstruction; Chronic Airflow Obstructions; Chronic Obstructive Airway Disease; Chronic Obstructive Lung Disease; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, RATE OF DECLINE OF LUNG FUNCTION IN; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, SEVERE EARLY-ONSET |
| | primary_id: | MESH:D029424 |
| | alt_id: | OMIM:141250; OMIM:606963 |
|
|
Pulmonary Disease, Chronic Obstructive
|
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
Severity |
ISS |
10 |
452,239 |
575,705 |
RGD:5128824 |
RGD |
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
Severity |
ISS |
10 |
452,239 |
575,705 |
RGD:5128827 |
RGD |
| G |
Ace |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
|
Susceptibility |
ISS |
10 |
95,361,338 |
95,381,455 |
RGD:4140480 |
RGD |
| G |
Ace |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
|
|
ISS |
10 |
95,361,338 |
95,381,455 |
RGD:4140487 |
RGD |
| G |
Ace |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
|
Disease_progression |
ISS |
10 |
95,361,338 |
95,381,455 |
RGD:4140912 |
RGD |
| G |
Adam33 |
ADAM metallopeptidase domain 33 |
|
Susceptibility |
ISS |
3 |
118,727,883 |
118,752,218 |
RGD:4145357 |
RGD |
| G |
Adam33 |
ADAM metallopeptidase domain 33 |
|
No_Association |
ISS |
3 |
118,727,883 |
118,752,218 |
RGD:4145358 |
RGD |
| G |
Adam33 |
ADAM metallopeptidase domain 33 |
|
|
ISS |
3 |
118,727,883 |
118,752,218 |
RGD:4145361 |
RGD |
| G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
|
Disease_progression |
ISS |
11 |
79,908,291 |
79,911,065 |
RGD:5686379 |
RGD |
| G |
Adora2a |
adenosine A2a receptor |
|
|
ISS |
20 |
13,815,719 |
13,834,131 |
RGD:4890385 |
RGD |
| G |
Adrb1 |
adrenoceptor beta 1 |
|
|
ISS |
1 |
263,025,655 |
263,027,055 |
RGD:5129114 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
|
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:5129114 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
Severity |
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4145080 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
|
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4144899 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
|
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4145093 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
No_Association |
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4145082 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
|
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4140935 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
Disease_progression |
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4145086 |
RGD |
| G |
Adrb2 |
adrenoceptor beta 2, surface |
|
Severity |
ISS |
18 |
58,174,958 |
58,177,000 |
RGD:4145095 |
RGD |
| G |
Ager |
advanced glycosylation end product-specific receptor |
|
|
ISS |
20 |
4,250,613 |
4,253,540 |
RGD:6767312 |
RGD |
| G |
Ang |
angiogenin, ribonuclease, RNase A family, 5 |
|
|
ISS |
15 |
27,083,089 |
27,083,526 |
RGD:6892708 |
RGD |
| G |
Bdkrb2 |
bradykinin receptor B2 |
|
|
ISS |
6 |
129,744,781 |
129,748,851 |
RGD:4890451 |
RGD |
| G |
C3 |
complement component 3 |
|
|
ISS |
|
|
|
RGD:5129504 |
RGD |
| G |
C5 |
complement component 5 |
|
Severity |
ISS |
3 |
14,011,115 |
14,102,744 |
RGD:5129705 |
RGD |
| G |
C5ar1 |
complement component 5a receptor 1 |
|
|
ISS |
|
|
|
RGD:5130165 |
RGD |
| G |
Cat |
catalase |
|
|
ISS |
3 |
88,654,077 |
88,686,212 |
RGD:4293707 |
RGD |
| G |
Ccl1 |
chemokine (C-C motif) ligand 1 |
|
Severity |
ISS |
10 |
70,380,498 |
70,383,276 |
RGD:4891410 |
RGD |
| G |
Ccl11 |
chemokine (C-C motif) ligand 11 |
|
Severity |
ISS |
10 |
70,279,161 |
70,283,762 |
RGD:4145389 |
RGD |
| G |
Ccl17 |
chemokine (C-C motif) ligand 17 |
|
|
ISS |
19 |
10,641,376 |
10,642,827 |
RGD:4145489 |
RGD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
|
ISS |
10 |
70,256,263 |
70,258,061 |
RGD:4891429 |
RGD |
| G |
Ccl22 |
chemokine (C-C motif) ligand 22 |
|
|
ISS |
19 |
10,697,324 |
10,704,129 |
RGD:4145489 |
RGD |
| G |
Ccl4 |
chemokine (C-C motif) ligand 4 |
|
|
ISS |
10 |
71,759,643 |
71,761,115 |
RGD:5130901 |
RGD |
| G |
Ccl4 |
chemokine (C-C motif) ligand 4 |
|
|
ISS |
10 |
71,759,643 |
71,761,115 |
RGD:5130900 |
RGD |
| G |
Ccl5 |
chemokine (C-C motif) ligand 5 |
|
|
ISS |
10 |
71,605,791 |
71,610,330 |
RGD:4891477 |
RGD |
| G |
Ccl7 |
chemokine (C-C motif) ligand 7 |
|
|
ISS |
10 |
70,267,281 |
70,269,131 |
RGD:6483765 |
RGD |
| G |
Ccl7 |
chemokine (C-C motif) ligand 7 |
|
|
ISS |
10 |
70,267,281 |
70,269,131 |
RGD:5130977 |
RGD |
| G |
Ccr3 |
chemokine (C-C motif) receptor 3 |
|
|
ISS |
8 |
128,759,943 |
128,769,341 |
RGD:4145632 |
RGD |
| G |
Ccr5 |
chemokine (C-C motif) receptor 5 |
|
|
ISS |
8 |
128,907,157 |
128,912,272 |
RGD:4892070 |
RGD |
| G |
Cd28 |
Cd28 molecule |
|
|
ISS |
9 |
59,342,273 |
59,367,743 |
RGD:5131618 |
RGD |
| G |
Cd28 |
Cd28 molecule |
|
|
ISS |
9 |
59,342,273 |
59,367,743 |
RGD:5131620 |
RGD |
| G |
Cd40 |
CD40 molecule, TNF receptor superfamily member 5 |
|
Severity |
ISS |
3 |
156,092,602 |
156,107,427 |
RGD:5490968 |
RGD |
| G |
Cd80 |
Cd80 molecule |
|
|
ISS |
11 |
64,045,358 |
64,070,072 |
RGD:4892292 |
RGD |
| G |
Cd86 |
CD86 molecule |
|
Severity |
ISS |
11 |
66,215,233 |
66,238,882 |
RGD:4892292 |
RGD |
| G |
Cd86 |
CD86 molecule |
|
Susceptibility |
ISS |
11 |
66,215,233 |
66,238,882 |
RGD:4891504 |
RGD |
| G |
Cftr |
cystic fibrosis transmembrane conductance regulator |
|
Disease_progression |
ISS |
4 |
43,874,852 |
44,041,870 |
RGD:4140431 |
RGD |
| G |
Chi3l1 |
chitinase 3-like 1 (cartilage glycoprotein-39) |
|
|
ISS |
13 |
47,139,658 |
47,147,591 |
RGD:4892658 |
RGD |
| G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
|
|
ISS |
17 |
71,214,906 |
71,218,463 |
RGD:5133441 |
RGD |
| G |
Clca1 |
chloride channel accessory 1 |
|
|
ISS |
2 |
243,057,135 |
243,084,146 |
RGD:1331524 |
RGD |
| G |
Clca1 |
chloride channel accessory 1 |
|
Severity |
ISS |
2 |
243,057,135 |
243,084,146 |
RGD:4145655 |
RGD |
| G |
Cma1 |
chymase 1, mast cell |
|
|
ISS |
15 |
34,083,202 |
34,084,387 |
RGD:5128552 |
RGD |
| G |
Col1a1 |
collagen, type I, alpha 1 |
|
|
ISS |
10 |
83,622,438 |
83,639,368 |
RGD:5131854 |
RGD |
| G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
|
|
ISS |
10 |
93,312,405 |
93,354,229 |
RGD:5147473 |
RGD |
| G |
Crp |
C-reactive protein, pentraxin-related |
|
Severity |
ISS |
13 |
88,702,243 |
88,703,153 |
RGD:5131279 |
RGD |
| G |
Crp |
C-reactive protein, pentraxin-related |
|
|
ISS |
13 |
88,702,243 |
88,703,153 |
RGD:5131278 |
RGD |
| G |
Csf2 |
colony stimulating factor 2 (granulocyte-macrophage) |
|
|
ISS |
10 |
39,665,850 |
39,667,831 |
RGD:5131476 |
RGD |
| G |
Ctgf |
connective tissue growth factor |
|
|
IEP |
1 |
21,327,099 |
21,330,215 |
RGD:2314483 |
RGD |
| G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
|
Susceptibility |
ISS |
9 |
59,495,773 |
59,501,300 |
RGD:4891504 |
RGD |
| G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
|
|
ISS |
9 |
59,495,773 |
59,501,300 |
RGD:4891499 |
RGD |
| G |
Cxcl1 |
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
|
|
ISS |
14 |
18,690,339 |
18,692,118 |
RGD:4890939 |
RGD |
| G |
Cxcl10 |
chemokine (C-X-C motif) ligand 10 |
|
|
ISS |
14 |
17,265,986 |
17,268,183 |
RGD:5135436 |
RGD |
| G |
Cxcl11 |
chemokine (C-X-C motif) ligand 11 |
|
|
ISS |
14 |
17,250,648 |
17,253,423 |
RGD:5135436 |
RGD |
| G |
Cxcl5 |
chemokine (C-X-C motif) ligand 5 |
|
Severity |
ISS |
14 |
18,825,357 |
18,826,269 |
RGD:5135248 |
RGD |
| G |
Cxcl9 |
chemokine (C-X-C motif) ligand 9 |
|
|
ISS |
14 |
17,284,085 |
17,288,996 |
RGD:5135436 |
RGD |
| G |
Cxcl9 |
chemokine (C-X-C motif) ligand 9 |
|
|
ISS |
14 |
17,284,085 |
17,288,996 |
RGD:4892070 |
RGD |
| G |
Cxcr2 |
chemokine (C-X-C motif) receptor 2 |
|
Severity |
ISS |
9 |
73,470,943 |
73,477,315 |
RGD:5135248 |
RGD |
| G |
Cxcr3 |
chemokine (C-X-C motif) receptor 3 |
|
|
ISS |
X |
89,794,276 |
89,796,927 |
RGD:4145632 |
RGD |
| G |
Cxcr3 |
chemokine (C-X-C motif) receptor 3 |
|
Disease_progression |
ISS |
X |
89,794,276 |
89,796,927 |
RGD:5135435 |
RGD |
| G |
Cyba |
cytochrome b-245, alpha polypeptide |
|
Susceptibility |
ISS |
19 |
52,713,150 |
52,721,609 |
RGD:4304108 |
RGD |
| G |
Cyba |
cytochrome b-245, alpha polypeptide |
|
Susceptibility |
ISS |
19 |
52,713,150 |
52,721,609 |
RGD:4293707 |
RGD |
| G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
No_Association |
ISS |
8 |
61,462,207 |
61,468,237 |
RGD:4892071 |
RGD |
| G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
Severity |
ISS |
8 |
61,462,207 |
61,468,237 |
RGD:4892045 |
RGD |
| G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
Susceptibility |
ISS |
8 |
61,462,207 |
61,468,237 |
RGD:4293707 |
RGD |
| G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
|
Susceptibility |
ISS |
8 |
61,439,062 |
61,447,861 |
RGD:4293707 |
RGD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
|
ISS |
1 |
200,918,521 |
200,928,919 |
RGD:4892219 |
RGD |
| G |
Defb1 |
defensin beta 1 |
|
No_Association |
ISS |
16 |
74,980,054 |
74,995,445 |
RGD:4892251 |
RGD |
| G |
Defb1 |
defensin beta 1 |
|
Susceptibility |
ISS |
16 |
74,980,054 |
74,995,445 |
RGD:4892257 |
RGD |
| G |
Defb1 |
defensin beta 1 |
|
|
ISS |
16 |
74,980,054 |
74,995,445 |
RGD:1331523 |
RGD |
| G |
Edn1 |
endothelin 1 |
|
|
ISS |
17 |
28,303,886 |
28,309,775 |
RGD:4145062 |
RGD |
| G |
Edn1 |
endothelin 1 |
|
|
ISS |
17 |
28,303,886 |
28,309,775 |
RGD:4144868 |
RGD |
| G |
Egfr |
epidermal growth factor receptor |
|
|
IEP |
14 |
97,617,358 |
97,788,211 |
RGD:7204496 |
RGD |
| G |
Egfr |
epidermal growth factor receptor |
|
|
ISS |
14 |
97,617,358 |
97,788,211 |
RGD:5131627 |
RGD |
| G |
Egr1 |
early growth response 1 |
|
|
ISS |
18 |
27,343,919 |
27,346,117 |
RGD:5131878 |
RGD |
| G |
Egr1 |
early growth response 1 |
|
|
ISS |
18 |
27,343,919 |
27,346,117 |
RGD:5131854 |
RGD |
| G |
Eln |
elastin |
|
|
ISS |
12 |
23,033,657 |
23,077,043 |
RGD:1580326 |
RGD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
No_Association |
ISS |
13 |
96,722,973 |
96,752,940 |
RGD:4889123 |
RGD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
Susceptibility |
ISS |
13 |
96,722,973 |
96,752,940 |
RGD:4889121 |
RGD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
No_Association |
ISS |
13 |
96,722,973 |
96,752,940 |
RGD:4889120 |
RGD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
No_Association |
ISS |
13 |
96,722,973 |
96,752,940 |
RGD:4889122 |
RGD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
|
ISS |
13 |
96,722,973 |
96,752,940 |
RGD:1601065 |
RGD |
| G |
Erbb3 |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
|
|
IEP |
7 |
1,858,057 |
1,877,353 |
RGD:2289953 |
RGD |
| G |
F2 |
coagulation factor II |
|
Severity |
ISS |
3 |
76,005,318 |
76,018,603 |
RGD:5147752 |
RGD |
| G |
F2rl1 |
coagulation factor II (thrombin) receptor-like 1 |
|
|
ISS |
2 |
25,886,177 |
25,899,128 |
RGD:4892586 |
RGD |
| G |
Flt1 |
FMS-related tyrosine kinase 1 |
|
|
ISS |
12 |
7,858,092 |
8,035,966 |
RGD:5684420 |
RGD |
| G |
Gc |
group specific component |
|
|
ISS |
14 |
20,166,243 |
20,197,060 |
RGD:5509932 |
RGD |
| G |
Gc |
group specific component |
|
|
IEA |
14 |
20,166,243 |
20,197,060 |
RGD:1331525 |
RGD |
| G |
Gstm1 |
glutathione S-transferase mu 1 |
|
Susceptibility |
ISS |
2 |
203,575,444 |
203,580,821 |
RGD:4140939 |
RGD |
| G |
Gstm1 |
glutathione S-transferase mu 1 |
|
|
ISS |
2 |
203,575,444 |
203,580,821 |
RGD:4142517 |
RGD |
| G |
Gstm1 |
glutathione S-transferase mu 1 |
|
Resistance |
ISS |
2 |
203,575,444 |
203,580,821 |
RGD:4142538 |
RGD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
|
ISS |
1 |
206,627,398 |
206,629,866 |
RGD:4142517 |
RGD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
No_Association |
ISS |
1 |
206,627,398 |
206,629,866 |
RGD:4142514 |
RGD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
Susceptibility |
ISS |
1 |
206,627,398 |
206,629,866 |
RGD:4140938 |
RGD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
|
ISS |
1 |
206,627,398 |
206,629,866 |
RGD:4142511 |
RGD |
| G |
Gstt1 |
glutathione S-transferase theta 1 |
|
Susceptibility |
ISS |
20 |
13,604,355 |
13,621,456 |
RGD:4140928 |
RGD |
| G |
Gstt1 |
glutathione S-transferase theta 1 |
|
|
ISS |
20 |
13,604,355 |
13,621,456 |
RGD:4140939 |
RGD |
| G |
Gzma |
granzyme A |
|
|
ISS |
2 |
44,488,295 |
44,500,128 |
RGD:5135520 |
RGD |
| G |
Gzmb |
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
|
|
ISS |
15 |
35,195,075 |
35,198,506 |
RGD:5135516 |
RGD |
| G |
Hmox1 |
heme oxygenase (decycling) 1 |
|
Susceptibility |
ISS |
19 |
13,963,139 |
13,969,960 |
RGD:4145372 |
RGD |
| G |
Hmox1 |
heme oxygenase (decycling) 1 |
|
Severity |
ISS |
19 |
13,963,139 |
13,969,960 |
RGD:4145371 |
RGD |
| G |
Hmox1 |
heme oxygenase (decycling) 1 |
|
|
ISS |
19 |
13,963,139 |
13,969,960 |
RGD:7240710 |
OMIM |
| G |
Hp |
haptoglobin |
|
|
ISS |
19 |
39,443,016 |
39,447,566 |
RGD:5144151 |
RGD |
| G |
Hspa4 |
heat shock protein 4 |
|
|
ISS |
10 |
38,705,629 |
38,749,058 |
RGD:5688779 |
RGD |
| G |
Hspa4 |
heat shock protein 4 |
|
No_Association |
ISS |
10 |
38,705,629 |
38,749,058 |
RGD:5688781 |
RGD |
| G |
Icam1 |
intercellular adhesion molecule 1 |
|
|
ISS |
8 |
20,040,177 |
20,051,939 |
RGD:4145446 |
RGD |
| G |
Icam1 |
intercellular adhesion molecule 1 |
|
|
ISS |
8 |
20,040,177 |
20,051,939 |
RGD:4145522 |
RGD |
| G |
Il12b |
interleukin 12B |
|
|
ISS |
10 |
29,558,955 |
29,568,331 |
RGD:4145423 |
RGD |
| G |
Il13 |
interleukin 13 |
|
Susceptibility |
ISS |
10 |
39,093,512 |
39,096,069 |
RGD:4145596 |
RGD |
| G |
Il13 |
interleukin 13 |
|
Susceptibility |
ISS |
10 |
39,093,512 |
39,096,069 |
RGD:4145601 |
RGD |
| G |
Il13 |
interleukin 13 |
|
Susceptibility |
ISS |
10 |
39,093,512 |
39,096,069 |
RGD:4145668 |
RGD |
| G |
Il13 |
interleukin 13 |
|
No_Association |
ISS |
10 |
39,093,512 |
39,096,069 |
RGD:4145714 |
RGD |
| G |
Il13ra1 |
interleukin 13 receptor, alpha 1 |
|
|
ISS |
X |
8,758,662 |
8,820,545 |
RGD:4145601 |
RGD |
| G |
Il16 |
interleukin 16 |
|
|
ISS |
1 |
139,908,061 |
140,000,146 |
RGD:5024924 |
RGD |
| G |
Il17a |
interleukin 17A |
|
|
ISS |
9 |
19,454,979 |
19,458,467 |
RGD:4889104 |
RGD |
| G |
Il18 |
interleukin 18 |
|
|
ISS |
8 |
53,936,584 |
53,943,228 |
RGD:4889551 |
RGD |
| G |
Il18 |
interleukin 18 |
|
|
ISS |
8 |
53,936,584 |
53,943,228 |
RGD:4889575 |
RGD |
| G |
Il18bp |
interleukin 18 binding protein |
|
|
ISS |
1 |
159,471,809 |
159,473,288 |
RGD:4889551 |
RGD |
| G |
Il1b |
interleukin 1 beta |
|
No_Association |
ISS |
3 |
116,964,422 |
116,970,867 |
RGD:4142868 |
RGD |
| G |
Il1b |
interleukin 1 beta |
|
Severity |
ISS |
3 |
116,964,422 |
116,970,867 |
RGD:4142866 |
RGD |
| G |
Il1b |
interleukin 1 beta |
|
No_Association |
ISS |
3 |
116,964,422 |
116,970,867 |
RGD:4142873 |
RGD |
| G |
Il1b |
interleukin 1 beta |
|
Susceptibility |
ISS |
3 |
116,964,422 |
116,970,867 |
RGD:4143169 |
RGD |
| G |
Il1rl1 |
interleukin 1 receptor-like 1 |
|
|
ISS |
9 |
39,577,879 |
39,624,781 |
RGD:5144227 |
RGD |
| G |
Il1rn |
interleukin 1 receptor antagonist |
|
No_Association |
ISS |
3 |
2,607,800 |
2,613,216 |
RGD:4142868 |
RGD |
| G |
Il1rn |
interleukin 1 receptor antagonist |
|
|
ISS |
3 |
2,607,800 |
2,613,216 |
RGD:4142861 |
RGD |
| G |
Il1rn |
interleukin 1 receptor antagonist |
|
Susceptibility |
ISS |
3 |
2,607,800 |
2,613,216 |
RGD:4142866 |
RGD |
| G |
Il27 |
interleukin 27 |
|
|
ISS |
1 |
185,730,394 |
185,735,604 |
RGD:5128484 |
RGD |
| G |
Il5 |
interleukin 5 |
|
|
ISS |
10 |
39,177,786 |
39,180,657 |
RGD:4890939 |
RGD |
| G |
Il5ra |
interleukin 5 receptor, alpha |
|
|
ISS |
4 |
142,067,108 |
142,098,051 |
RGD:5128619 |
RGD |
| G |
Il6 |
interleukin 6 |
|
|
ISS |
4 |
456,799 |
461,376 |
RGD:4143243 |
RGD |
| G |
Il9 |
interleukin 9 |
|
|
ISS |
17 |
14,068,757 |
14,071,880 |
RGD:5128691 |
RGD |
| G |
Kdr |
kinase insert domain receptor |
|
|
ISS |
|
|
|
RGD:5684420 |
RGD |
| G |
Lep |
leptin |
|
|
ISS |
4 |
55,943,837 |
55,945,938 |
RGD:5128772 |
RGD |
| G |
Lep |
leptin |
|
Severity |
ISS |
4 |
55,943,837 |
55,945,938 |
RGD:5128777 |
RGD |
| G |
Lep |
leptin |
|
|
ISS |
4 |
55,943,837 |
55,945,938 |
RGD:5128778 |
RGD |
| G |
Lepr |
leptin receptor |
|
|
ISS |
5 |
122,320,075 |
122,503,449 |
RGD:5128813 |
RGD |
| G |
Lepr |
leptin receptor |
|
Disease_progression |
ISS |
5 |
122,320,075 |
122,503,449 |
RGD:5128813 |
RGD |
| G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
|
Severity |
ISS |
10 |
52,009,149 |
52,041,599 |
RGD:5490968 |
RGD |
| G |
Mapk8 |
mitogen-activated protein kinase 8 |
|
Severity |
ISS |
16 |
8,925,133 |
9,004,897 |
RGD:5490968 |
RGD |
| G |
Mbl2 |
mannose-binding lectin (protein C) 2 |
|
|
ISS |
1 |
233,978,931 |
233,983,824 |
RGD:4889421 |
RGD |
| G |
Mbl2 |
mannose-binding lectin (protein C) 2 |
|
|
ISS |
1 |
233,978,931 |
233,983,824 |
RGD:4889448 |
RGD |
| G |
Mmp1 |
matrix metallopeptidase 1 (interstitial collagenase) |
|
|
IEP |
8 |
4,333,773 |
4,354,284 |
RGD:7207216 |
RGD |
| G |
Mmp9 |
matrix metallopeptidase 9 |
|
Severity |
ISS |
3 |
155,985,473 |
155,993,433 |
RGD:5130149 |
RGD |
| G |
Mmp9 |
matrix metallopeptidase 9 |
|
Susceptibility |
ISS |
3 |
155,985,473 |
155,993,433 |
RGD:5129494 |
RGD |
| G |
Mmp9 |
matrix metallopeptidase 9 |
|
|
ISS |
3 |
155,985,473 |
155,993,433 |
RGD:5129553 |
RGD |
| G |
Mpo |
myeloperoxidase |
|
|
IEP |
10 |
76,085,872 |
76,097,012 |
RGD:5130997 |
RGD |
| G |
Mpo |
myeloperoxidase |
|
Severity |
ISS |
10 |
76,085,872 |
76,097,012 |
RGD:5130993 |
RGD |
| G |
Muc1 |
mucin 1, cell surface associated |
|
|
IEP |
2 |
181,399,482 |
181,403,640 |
RGD:5131160 |
RGD |
| G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
|
|
ISS |
|
|
|
RGD:4145655 |
RGD |
| G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
|
|
ISS |
|
|
|
RGD:5131190 |
RGD |
| G |
Muc5b |
mucin 5B, oligomeric mucus/gel-forming |
|
|
ISS |
1 |
201,962,340 |
201,997,147 |
RGD:5131169 |
RGD |
| G |
Nat1 |
N-acetyltransferase 1 (arylamine N-acetyltransferase) |
|
Susceptibility |
ISS |
16 |
23,845,894 |
23,876,528 |
RGD:5131863 |
RGD |
| G |
Nat1 |
N-acetyltransferase 1 (arylamine N-acetyltransferase) |
|
Susceptibility |
ISS |
16 |
23,845,894 |
23,876,528 |
RGD:4892219 |
RGD |
| G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
|
|
ISS |
3 |
58,366,693 |
58,394,116 |
RGD:5134980 |
RGD |
| G |
Nod2 |
nucleotide-binding oligomerization domain containing 2 |
|
|
ISS |
19 |
19,662,337 |
19,697,341 |
RGD:5508720 |
RGD |
| G |
Nos1 |
nitric oxide synthase 1, neuronal |
|
Severity |
ISS |
12 |
39,812,500 |
39,869,484 |
RGD:5132607 |
RGD |
| G |
Nos1 |
nitric oxide synthase 1, neuronal |
|
Severity |
ISS |
12 |
39,812,500 |
39,869,484 |
RGD:5132628 |
RGD |
| G |
Nos2 |
nitric oxide synthase 2, inducible |
|
|
ISS |
10 |
65,036,884 |
65,072,453 |
RGD:4891444 |
RGD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
|
ISS |
19 |
37,251,147 |
37,266,040 |
RGD:5134980 |
RGD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
Susceptibility |
ISS |
19 |
37,251,147 |
37,266,040 |
RGD:5133267 |
RGD |
| G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
|
|
ISS |
18 |
32,371,496 |
32,459,145 |
RGD:4892318 |
RGD |
| G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
|
|
ISS |
18 |
32,371,496 |
32,459,145 |
RGD:4892564 |
RGD |
| G |
Ntf3 |
neurotrophin 3 |
|
|
ISS |
4 |
162,435,781 |
162,506,961 |
RGD:4891120 |
RGD |
| G |
Ntrk1 |
neurotrophic tyrosine kinase, receptor, type 1 |
|
|
ISS |
2 |
179,838,740 |
179,855,545 |
RGD:5684530 |
RGD |
| G |
Plau |
plasminogen activator, urokinase |
|
|
IPM |
15 |
3,680,072 |
3,686,232 |
RGD:6484146 |
RGD |
| G |
Plau |
plasminogen activator, urokinase |
|
Severity |
ISS |
15 |
3,680,072 |
3,686,232 |
RGD:6483803 |
RGD |
| G |
Plaur |
plasminogen activator, urokinase receptor |
|
|
IEP |
1 |
79,708,646 |
79,712,881 |
RGD:6484146 |
RGD |
| G |
Ppargc1a |
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
|
|
ISS |
14 |
64,278,115 |
64,370,912 |
RGD:6484530 |
RGD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
|
ISS |
13 |
64,427,288 |
64,432,978 |
RGD:5143926 |
RGD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
|
ISS |
13 |
64,427,288 |
64,432,978 |
RGD:5135277 |
RGD |
| G |
Selp |
selectin P |
|
Severity |
ISS |
13 |
79,886,614 |
79,922,180 |
RGD:6478682 |
RGD |
| G |
Serpina1 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
|
|
ISS |
6 |
127,998,617 |
128,021,719 |
RGD:4140387 |
RGD |
| G |
Serpina3n |
serine (or cysteine) peptidase inhibitor, clade A, member 3N |
|
|
ISS |
6 |
128,461,775 |
128,469,309 |
RGD:5147433 |
RGD |
| G |
Serpina3n |
serine (or cysteine) peptidase inhibitor, clade A, member 3N |
|
|
ISS |
6 |
128,461,775 |
128,469,309 |
RGD:5147449 |
RGD |
| G |
Serpina3n |
serine (or cysteine) peptidase inhibitor, clade A, member 3N |
|
Susceptibility |
ISS |
6 |
128,461,775 |
128,469,309 |
RGD:5147441 |
RGD |
| G |
Serpine1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
|
|
ISS |
12 |
20,931,996 |
20,942,374 |
RGD:4144041 |
RGD |
| G |
Serpine1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
|
|
IEP |
12 |
20,931,996 |
20,942,374 |
RGD:6484146 |
RGD |
| G |
Sftpa1 |
surfactant protein A1 |
|
Susceptibility |
ISS |
16 |
17,570,887 |
17,574,389 |
RGD:4143423 |
RGD |
| G |
Sftpa1 |
surfactant protein A1 |
|
|
ISS |
16 |
17,570,887 |
17,574,389 |
RGD:4143281 |
RGD |
| G |
Sftpa1 |
surfactant protein A1 |
|
|
ISS |
16 |
17,570,887 |
17,574,389 |
RGD:4143288 |
RGD |
| G |
Sftpb |
surfactant protein B |
|
Severity |
ISS |
4 |
105,609,410 |
105,618,452 |
RGD:4143290 |
RGD |
| G |
Sftpb |
surfactant protein B |
|
|
ISS |
4 |
105,609,410 |
105,618,452 |
RGD:4143396 |
RGD |
| G |
Sftpb |
surfactant protein B |
|
Susceptibility |
ISS |
4 |
105,609,410 |
105,618,452 |
RGD:4143402 |
RGD |
| G |
Sftpb |
surfactant protein B |
|
Susceptibility |
ISS |
4 |
105,609,410 |
105,618,452 |
RGD:4143423 |
RGD |
| G |
Sftpc |
surfactant protein C |
|
Disease_progression |
ISS |
15 |
50,923,105 |
50,926,047 |
RGD:4144115 |
RGD |
| G |
Sftpd |
surfactant protein D |
|
Severity |
ISS |
|
|
|
RGD:4143492 |
RGD |
| G |
Sftpd |
surfactant protein D |
|
Susceptibility |
ISS |
|
|
|
RGD:4143487 |
RGD |
| G |
Sftpd |
surfactant protein D |
|
|
ISS |
|
|
|
RGD:4143281 |
RGD |
| G |
Sftpd |
surfactant protein D |
|
|
IEP |
|
|
|
RGD:4143501 |
RGD |
| G |
Slc6a4 |
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
|
Susceptibility |
ISS |
10 |
67,134,790 |
67,155,891 |
RGD:4889426 |
RGD |
| G |
Sod3 |
superoxide dismutase 3, extracellular |
|
|
ISS |
14 |
63,381,447 |
63,387,180 |
RGD:1581270 |
RGD |
| G |
Tgfb1 |
transforming growth factor, beta 1 |
|
No_Association |
ISS |
1 |
80,894,705 |
80,911,020 |
RGD:4145140 |
RGD |
| G |
Tgfb1 |
transforming growth factor, beta 1 |
|
|
IPM |
1 |
80,894,705 |
80,911,020 |
RGD:4145292 |
RGD |
| G |
Tgfb1 |
transforming growth factor, beta 1 |
|
Susceptibility |
ISS |
1 |
80,894,705 |
80,911,020 |
RGD:4145115 |
RGD |
| G |
Tlr4 |
toll-like receptor 4 |
|
|
ISS |
5 |
83,564,100 |
83,577,735 |
RGD:4144145 |
RGD |
| G |
Tlr4 |
toll-like receptor 4 |
|
Susceptibility |
ISS |
5 |
83,564,100 |
83,577,735 |
RGD:4144119 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
|
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4143273 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
No_Association |
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4145714 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
|
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4143272 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
|
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4143270 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
|
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4143421 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
Disease_progression |
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4143391 |
RGD |
| G |
Tnf |
tumor necrosis factor |
|
|
ISS |
20 |
3,661,000 |
3,663,618 |
RGD:4143424 |
RGD |
| G |
Tnfrsf1a |
tumor necrosis factor receptor superfamily, member 1a |
|
Severity |
ISS |
4 |
162,172,563 |
162,185,252 |
RGD:5131203 |
RGD |
| G |
Tnfrsf1b |
tumor necrosis factor receptor superfamily, member 1b |
|
Severity |
ISS |
5 |
163,666,541 |
163,697,484 |
RGD:5131154 |
RGD |
| G |
Vegfa |
vascular endothelial growth factor A |
|
|
ISS |
9 |
10,520,730 |
10,536,071 |
RGD:5684420 |
RGD |
Bronchitis, Chronic
|
| G |
Ccl11 |
chemokine (C-C motif) ligand 11 |
|
|
ISS |
10 |
70,279,161 |
70,283,762 |
RGD:4145442 |
RGD |
| G |
Cftr |
cystic fibrosis transmembrane conductance regulator |
|
Susceptibility |
ISS |
4 |
43,874,852 |
44,041,870 |
RGD:4140475 |
RGD |
| G |
Cftr |
cystic fibrosis transmembrane conductance regulator |
|
|
ISS |
4 |
43,874,852 |
44,041,870 |
RGD:4140484 |
RGD |
| G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
|
|
ISS |
9 |
59,495,773 |
59,501,300 |
RGD:4891509 |
RGD |
| G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
Susceptibility |
ISS |
8 |
61,462,207 |
61,468,237 |
RGD:4142512 |
RGD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
|
ISS |
1 |
200,918,521 |
200,928,919 |
RGD:4889126 |
RGD |
| G |
Edn1 |
endothelin 1 |
|
|
ISS |
17 |
28,303,886 |
28,309,775 |
RGD:4145074 |
RGD |
| G |
Gc |
group specific component |
|
Susceptibility |
ISS |
14 |
20,166,243 |
20,197,060 |
RGD:5129516 |
RGD |
| G |
Gstm1 |
glutathione S-transferase mu 1 |
|
Severity |
ISS |
2 |
203,575,444 |
203,580,821 |
RGD:4142513 |
RGD |
| G |
Gstt1 |
glutathione S-transferase theta 1 |
|
Susceptibility |
ISS |
20 |
13,604,355 |
13,621,456 |
RGD:4142512 |
RGD |
| G |
Icam1 |
intercellular adhesion molecule 1 |
|
|
IEP |
8 |
20,040,177 |
20,051,939 |
RGD:2308951 |
RGD |
| G |
Il10 |
interleukin 10 |
|
|
IEP |
13 |
43,953,900 |
43,957,766 |
RGD:2308951 |
RGD |
| G |
Il13 |
interleukin 13 |
|
|
ISS |
10 |
39,093,512 |
39,096,069 |
RGD:4759835 |
RGD |
| G |
Il15 |
interleukin 15 |
|
|
ISS |
19 |
27,487,268 |
27,498,973 |
RGD:4990461 |
RGD |
| G |
Mpo |
myeloperoxidase |
|
|
IEP |
10 |
76,085,872 |
76,097,012 |
RGD:5130990 |
RGD |
| G |
Nos2 |
nitric oxide synthase 2, inducible |
|
|
IED |
10 |
65,036,884 |
65,072,453 |
RGD:4891494 |
RGD |
Term paths to the root
|