ONTOLOGY REPORT - ANNOTATIONS

Term:Endotoxemia
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Accession:RDO:0007272 term browser browse the term
Definition:A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
Synonyms:exact_synonym: Endotoxemias
 primary_id: MESH:D019446

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Endotoxemia term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 GBrowse link ISS 2 169,779,449 169,887,833 RGD:1598596 RGD
G ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link ISS 10 101,542,463 101,611,662 RGD:1598611 RGD
G ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 GBrowse link ISS 11 17,414,432 17,498,449 RGD:2301914 RGD
G ACHE acetylcholinesterase GBrowse link IED 7 100,487,615 100,493,541 RGD:5688055 RGD
G ACTC1 actin, alpha, cardiac muscle 1 GBrowse link Induced ISS 15 35,080,297 35,087,927 RGD:1598729 RGD
G ADRA2A adrenoceptor alpha 2A GBrowse link Onset ISS 10 112,836,790 112,840,665 RGD:6480487 RGD
G AGTR1 angiotensin II receptor, type 1 GBrowse link ISS 3 148,415,658 148,460,790 RGD:6903849 RGD
G AGTR2 angiotensin II receptor, type 2 GBrowse link ISS X 115,301,958 115,306,225 RGD:6903849 RGD
G ALDOA aldolase A, fructose-bisphosphate GBrowse link Induced ISS 16 30,064,411 30,081,741 RGD:1599054 RGD
G APOA1 apolipoprotein A-I GBrowse link Treatment IED 11 116,706,469 116,708,338 RGD:7241573 RGD
G APOA1 apolipoprotein A-I GBrowse link Treatment ISS 11 116,706,469 116,708,338 RGD:7241868 RGD
G APOB apolipoprotein B (including Ag(x) antigen) GBrowse link ISS 2 21,224,301 21,266,945 RGD:1599165 RGD
G APOE apolipoprotein E GBrowse link IED 19 45,409,039 45,412,650 RGD:6904216 RGD
G ASL argininosuccinate lyase GBrowse link ISS 7 65,540,776 65,558,330 RGD:1599265 RGD
G ASS1 argininosuccinate synthase 1 GBrowse link ISS 9 133,320,094 133,376,661 RGD:1599265 RGD
G ATF2 activating transcription factor 2 GBrowse link ISS 2 175,936,978 176,032,934 RGD:5135029 RGD
G BCHE butyrylcholinesterase GBrowse link IED 3 165,490,692 165,555,253 RGD:5688055 RGD
G CASP1 caspase 1, apoptosis-related cysteine peptidase GBrowse link ISS 11 104,896,235 104,905,884 RGD:2315892 RGD
G CASP7 caspase 7, apoptosis-related cysteine peptidase GBrowse link ISS 10 115,438,921 115,490,668 RGD:5684539 RGD
G CCL2 chemokine (C-C motif) ligand 2 GBrowse link ISS 17 32,582,296 32,584,222 RGD:2307004 RGD
G CCL5 chemokine (C-C motif) ligand 5 GBrowse link ISS 17 34,198,495 34,207,377 RGD:2307171 RGD
G CCR1 chemokine (C-C motif) receptor 1 GBrowse link ISS 3 46,243,200 46,249,832 RGD:5688178 RGD
G CD14 CD14 molecule GBrowse link ISS 5 140,011,313 140,013,286 RGD:724637 RGD
G CD40 CD40 molecule, TNF receptor superfamily member 5 GBrowse link ISS 20 44,746,906 44,758,384 RGD:5490974 RGD
G CX3CL1 chemokine (C-X3-C motif) ligand 1 GBrowse link ISS 16 57,406,414 57,418,956 RGD:4891965 RGD
G CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link ISS 4 74,735,109 74,737,019 RGD:5135254 RGD
G CXCL2 chemokine (C-X-C motif) ligand 2 GBrowse link ISS 4 74,962,752 74,964,997 RGD:5135254 RGD
G CXCL5 chemokine (C-X-C motif) ligand 5 GBrowse link ISS 4 74,861,359 74,864,416 RGD:5135254 RGD
G EPHX2 epoxide hydrolase 2, cytoplasmic GBrowse link ISS 8 27,348,519 27,402,439 RGD:5688360 RGD
G F2 coagulation factor II (thrombin) GBrowse link ISS 11 46,740,743 46,761,056 RGD:5147765 RGD
G F2 coagulation factor II (thrombin) GBrowse link ISS 11 46,740,743 46,761,056 RGD:5147779 RGD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link ISS 1 94,994,732 95,007,413 RGD:5147765 RGD
G GHR growth hormone receptor GBrowse link ISS 5 42,423,877 42,721,980 RGD:2307380 RGD
G HSPD1 heat shock 60kDa protein 1 (chaperonin) GBrowse link ISS 2 198,351,308 198,364,998 RGD:1624232 RGD
G ICAM1 intercellular adhesion molecule 1 GBrowse link ISS 19 10,381,517 10,397,291 RGD:4145502 RGD
G IL1A interleukin 1, alpha GBrowse link ISS 2 113,531,492 113,542,971 RGD:6907109 RGD
G IL1B interleukin 1, beta GBrowse link ISS 2 113,587,337 113,594,356 RGD:1626625 RGD
G IL6 interleukin 6 (interferon, beta 2) GBrowse link ISS 7 22,766,766 22,771,621 RGD:2307179 RGD
G IL6 interleukin 6 (interferon, beta 2) GBrowse link ISS 7 22,766,766 22,771,621 RGD:5147765 RGD
G IRS1 insulin receptor substrate 1 GBrowse link ISS 2 227,596,033 227,663,506 RGD:6483008 RGD
G ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) GBrowse link ISS 17 42,449,550 42,466,873 RGD:2316360 RGD
G ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) GBrowse link ISS 17 45,331,208 45,390,077 RGD:2316360 RGD
G KEAP1 kelch-like ECH-associated protein 1 GBrowse link ISS 19 10,596,796 10,614,054 RGD:6892951 RGD
G MAP2 microtubule-associated protein 2 GBrowse link ISS 2 210,288,771 210,598,834 RGD:6483086 RGD
G MAPK14 mitogen-activated protein kinase 14 GBrowse link ISS 6 35,995,454 36,079,013 RGD:5135029 RGD
G MC4R melanocortin 4 receptor GBrowse link ISS 18 58,038,564 58,040,001 RGD:6484214 RGD
G MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link ISS 22 24,236,565 24,237,409 RGD:1641983 RGD
G MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) GBrowse link ISS 11 102,706,528 102,714,342 RGD:2290426 RGD
G MT2A metallothionein 2A GBrowse link ISS 16 56,642,478 56,643,409 RGD:6483852 RGD
G NOS2 nitric oxide synthase 2, inducible GBrowse link ISS 17 26,083,792 26,127,555 RGD:4891470 RGD
G NOS2 nitric oxide synthase 2, inducible GBrowse link ISS 17 26,083,792 26,127,555 RGD:5147779 RGD
G NPY2R neuropeptide Y receptor Y2 GBrowse link ISS 4 156,129,781 156,138,228 RGD:1580787 RGD
G NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) GBrowse link ISS 5 142,657,496 142,815,077 RGD:4892561 RGD
G PCSK1 proprotein convertase subtilisin/kexin type 1 GBrowse link ISS 5 95,726,040 95,768,985 RGD:6483567 RGD
G PCSK2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISS 20 17,206,752 17,465,223 RGD:6483567 RGD
G PECAM1 platelet/endothelial cell adhesion molecule 1 GBrowse link ISS 17 62,396,775 62,404,856 RGD:6771174 RGD
G PGF placental growth factor GBrowse link ISS 14 75,408,533 75,422,467 RGD:6483601 RGD
G PPARG peroxisome proliferator-activated receptor gamma GBrowse link ISS 3 12,329,349 12,475,855 RGD:5135029 RGD
G PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link ISS 5 40,759,481 40,798,297 RGD:6484543 RGD
G PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) GBrowse link ISS 1 186,640,944 186,649,559 RGD:5135029 RGD
G SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link Resistance ISS 1 173,872,942 173,886,516 RGD:1599326 RGD
G SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link ISS 1 173,872,942 173,886,516 RGD:5147765 RGD
G SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link ISS 1 173,872,942 173,886,516 RGD:5147779 RGD
G SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISS 7 100,770,370 100,782,547 RGD:5147765 RGD
G SLC18A3 solute carrier family 18 (vesicular acetylcholine), member 3 GBrowse link ISS 10 50,818,347 50,820,766 RGD:5686693 RGD
G SOCS1 suppressor of cytokine signaling 1 GBrowse link ISS 16 11,348,274 11,350,039 RGD:2298923 RGD
G SOCS3 suppressor of cytokine signaling 3 GBrowse link ISS 17 76,352,859 76,356,158 RGD:625688 RGD
G SOCS3 suppressor of cytokine signaling 3 GBrowse link ISS 17 76,352,859 76,356,158 RGD:2298923 RGD
G SPARC secreted protein, acidic, cysteine-rich (osteonectin) GBrowse link ISS 5 151,040,657 151,066,615 RGD:2300026 RGD
G STAT5B signal transducer and activator of transcription 5B GBrowse link ISS 17 40,351,195 40,428,424 RGD:1601383 RGD
G TBXA2R thromboxane A2 receptor GBrowse link ISS 19 3,594,504 3,606,831 RGD:1601450 RGD
G TBXAS1 thromboxane A synthase 1 (platelet) GBrowse link ISS 7 139,478,047 139,720,125 RGD:1601450 RGD
G THBD thrombomodulin GBrowse link IED 20 23,026,270 23,030,301 RGD:5684988 RGD
G THBD thrombomodulin GBrowse link ISS 20 23,026,270 23,030,301 RGD:1601652 RGD
G THBD thrombomodulin GBrowse link ISS 20 23,026,270 23,030,301 RGD:5685037 RGD
G TIMP3 TIMP metallopeptidase inhibitor 3 GBrowse link ISS 22 33,196,802 33,259,028 RGD:2290426 RGD
G TLR2 toll-like receptor 2 GBrowse link Treatment ISS 4 154,605,441 154,627,243 RGD:7241094 RGD
G TLR4 toll-like receptor 4 GBrowse link Treatment ISS 9 120,466,453 120,479,769 RGD:7241094 RGD
G TNF tumor necrosis factor GBrowse link ISS 6 31,543,344 31,546,113 RGD:4891465 RGD
G TNF tumor necrosis factor GBrowse link ISS 6 31,543,344 31,546,113 RGD:5147779 RGD
G TNF tumor necrosis factor GBrowse link ISS 6 31,543,344 31,546,113 RGD:5147765 RGD
G VCAM1 vascular cell adhesion molecule 1 GBrowse link ISS 1 101,185,196 101,204,601 RGD:7240511 RGD
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Path 1
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  Diseases 29328
    Bacterial Infections and Mycoses 1478
      Bacterial Infections 523
        Bacteremia 88
          Endotoxemia 82
Path 2
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  Diseases 29328
    Pathological Conditions, Signs and Symptoms 5330
      Pathologic Processes 2117
        Inflammation 371
          Systemic Inflammatory Response Syndrome 241
            Sepsis 234
              Bacteremia 88
                Endotoxemia 82
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