ONTOLOGY REPORT - ANNOTATIONS

Term:Endotoxemia
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Accession:RDO:0007272 term browser browse the term
Definition:A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
Synonyms:exact_synonym: Endotoxemias
 primary_id: MESH:D019446

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Endotoxemia term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 IEP RGD:1598596 RGD
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B GBrowse link IEP 4 21,829,489 21,912,239 RGD:1598596 RGD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 IEP RGD:1598611 RGD
G Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 GBrowse link IEP 1 96,622,574 96,703,723 RGD:2301914 RGD
G Ache acetylcholinesterase ISS RGD:5688055 RGD
G Actc1 actin, alpha, cardiac muscle 1 GBrowse link Induced IEP 3 99,901,022 99,906,558 RGD:1598729 RGD
G Adra2a adrenoceptor alpha 2A Onset IEP RGD:6480487 RGD
G Agtr2 angiotensin II receptor, type 2 IEP RGD:6903849 RGD
G Aldoa aldolase A, fructose-bisphosphate GBrowse link Induced IEP 1 185,970,658 185,974,615 RGD:1599054 RGD
G Apoa1 apolipoprotein A-I Treatment ISS RGD:7241573 RGD
G Apoa1 apolipoprotein A-I Treatment IED RGD:7241868 RGD
G Apob apolipoprotein B GBrowse link IEP 6 31,508,060 31,548,083 RGD:1599165 RGD
G Apoe apolipoprotein E GBrowse link ISS 1 79,003,634 79,006,387 RGD:6904216 RGD
G Asl argininosuccinate lyase GBrowse link IEP 12 27,702,882 27,720,230 RGD:1599265 RGD
G Ass1 argininosuccinate synthase 1 GBrowse link IEP 3 10,578,717 10,622,332 RGD:1599265 RGD
G Atf2 activating transcription factor 2 GBrowse link IEP 3 56,403,676 56,496,473 RGD:5135029 RGD
G Bche butyrylcholinesterase GBrowse link ISS 2 164,329,613 164,427,994 RGD:5688055 RGD
G Casp1 caspase 1 GBrowse link IPM 8 2,027,976 2,036,872 RGD:2315892 RGD
G Casp7 caspase 7 GBrowse link ISS 1 262,689,300 262,721,591 RGD:5684539 RGD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link IEP 10 70,256,263 70,258,061 RGD:2307004 RGD
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link IEP 10 71,605,791 71,610,330 RGD:2307171 RGD
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link ISS 8 128,693,658 128,699,213 RGD:5688178 RGD
G Cd14 CD14 molecule GBrowse link IEP 18 29,374,593 29,376,190 RGD:724637 RGD
G Cd40 CD40 molecule, TNF receptor superfamily member 5 GBrowse link ISS 3 156,092,602 156,107,427 RGD:5490974 RGD
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 GBrowse link IEP 19 10,666,940 10,676,424 RGD:4891965 RGD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link ISS 14 18,690,339 18,692,118 RGD:5135254 RGD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link ISS 14 18,677,129 18,679,175 RGD:5135254 RGD
G Cxcl5 chemokine (C-X-C motif) ligand 5 GBrowse link ISS 14 18,825,357 18,826,269 RGD:5135254 RGD
G Ephx2 epoxide hydrolase 2, cytoplasmic GBrowse link ISS 15 45,497,660 45,556,101 RGD:5688360 RGD
G F2 coagulation factor II GBrowse link IED 3 76,005,318 76,018,603 RGD:5147765 RGD
G F2 coagulation factor II GBrowse link IED 3 76,005,318 76,018,603 RGD:5147779 RGD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link IED 2 218,371,050 218,382,645 RGD:5147765 RGD
G Ghr growth hormone receptor GBrowse link IEP 2 52,496,517 52,658,066 RGD:2307380 RGD
G Hspd1 heat shock protein 1 (chaperonin) GBrowse link IEP 9 53,884,193 53,895,043 RGD:1624232 RGD
G Icam1 intercellular adhesion molecule 1 GBrowse link IEP 8 20,040,177 20,051,939 RGD:4145502 RGD
G Il10 interleukin 10 GBrowse link IEP 13 43,953,900 43,957,766 RGD:2311055 RGD
G Il1a interleukin 1 alpha GBrowse link ISS 3 116,913,612 116,924,114 RGD:6907109 RGD
G Il1b interleukin 1 beta GBrowse link IEP 3 116,964,422 116,970,867 RGD:1626625 RGD
G Il6 interleukin 6 GBrowse link IED 4 456,799 461,376 RGD:2307179 RGD
G Il6 interleukin 6 GBrowse link IED 4 456,799 461,376 RGD:5147765 RGD
G Irs1 insulin receptor substrate 1 GBrowse link ISS 9 81,585,251 81,638,071 RGD:6483008 RGD
G Itga2b integrin, alpha 2B GBrowse link IPM 10 91,557,086 91,574,194 RGD:2316360 RGD
G Itgb3 integrin, beta 3 IPM RGD:2316360 RGD
G Keap1 Kelch-like ECH-associated protein 1 GBrowse link ISS 8 20,259,178 20,266,351 RGD:6892951 RGD
G Map2 microtubule-associated protein 2 GBrowse link ISS 9 65,174,376 65,256,003 RGD:6483086 RGD
G Mapk14 mitogen activated protein kinase 14 GBrowse link IEP 20 6,939,249 7,000,378 RGD:5135029 RGD
G Mc4r melanocortin 4 receptor GBrowse link IEP 18 63,390,922 63,392,809 RGD:6484214 RGD
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link IEP 20 13,191,986 13,192,851 RGD:1641983 RGD
G Mmp3 matrix metallopeptidase 3 GBrowse link IEP 8 4,315,601 4,329,146 RGD:2290426 RGD
G Mt2A metallothionein 2A GBrowse link IEP 19 11,267,811 11,268,585 RGD:6483852 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IEP 10 65,036,884 65,072,453 RGD:4891470 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IED 10 65,036,884 65,072,453 RGD:5147779 RGD
G Npy2r neuropeptide Y receptor Y2 GBrowse link IED 2 150,554,962 150,556,108 RGD:1580787 RGD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link IED 18 32,371,496 32,459,145 RGD:4892561 RGD
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link IEP 2 1,923,309 1,970,238 RGD:6483567 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link IEP 3 131,925,648 132,256,178 RGD:6483567 RGD
G Pecam1 platelet/endothelial cell adhesion molecule 1 GBrowse link ISS 10 96,056,220 96,057,232 RGD:6771174 RGD
G Pgf placental growth factor GBrowse link ISS 6 109,215,540 109,226,122 RGD:6483601 RGD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link IEP 4 151,492,220 151,617,331 RGD:5135029 RGD
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link ISS 2 54,327,821 54,360,462 RGD:6484543 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link IEP 13 64,427,288 64,432,978 RGD:5135029 RGD
G Serpinc1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link Resistance IED 13 76,548,456 76,562,724 RGD:1599326 RGD
G Serpinc1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link IED 13 76,548,456 76,562,724 RGD:5147765 RGD
G Serpinc1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link IED 13 76,548,456 76,562,724 RGD:5147779 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link IEP 12 20,931,996 20,942,374 RGD:5147765 RGD
G Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 GBrowse link IEP 16 7,969,738 7,972,599 RGD:5686693 RGD
G Socs1 suppressor of cytokine signaling 1 GBrowse link ISS 10 4,819,971 4,820,609 RGD:2298923 RGD
G Socs3 suppressor of cytokine signaling 3 GBrowse link IEP 10 107,958,468 107,959,330 RGD:625688 RGD
G Socs3 suppressor of cytokine signaling 3 GBrowse link ISS 10 107,958,468 107,959,330 RGD:2298923 RGD
G Sparc secreted protein, acidic, cysteine-rich (osteonectin) GBrowse link IEP 10 40,809,730 40,831,481 RGD:2300026 RGD
G Stat5b signal transducer and activator of transcription 5B GBrowse link IED 10 89,716,624 89,743,134 RGD:1601383 RGD
G Tbxa2r thromboxane A2 receptor GBrowse link IED 7 9,867,739 9,872,536 RGD:1601450 RGD
G Tbxas1 thromboxane A synthase 1, platelet GBrowse link IED 4 66,502,253 66,677,538 RGD:1601450 RGD
G Thbd thrombomodulin GBrowse link ISS 3 137,158,955 137,162,607 RGD:5684988 RGD
G Thbd thrombomodulin GBrowse link IEP 3 137,158,955 137,162,607 RGD:1601652 RGD
G Thbd thrombomodulin GBrowse link ISS 3 137,158,955 137,162,607 RGD:5685037 RGD
G Timp3 TIMP metallopeptidase inhibitor 3 GBrowse link IEP 7 19,677,144 19,727,072 RGD:2290426 RGD
G Tlr2 toll-like receptor 2 GBrowse link Treatment IED 2 175,607,990 175,613,992 RGD:7241094 RGD
G Tlr4 toll-like receptor 4 GBrowse link Treatment IED 5 83,564,100 83,577,735 RGD:7241094 RGD
G Tnf tumor necrosis factor GBrowse link IEP 20 3,661,000 3,663,618 RGD:4891465 RGD
G Tnf tumor necrosis factor GBrowse link IED 20 3,661,000 3,663,618 RGD:5147765 RGD
G Tnf tumor necrosis factor GBrowse link IED 20 3,661,000 3,663,618 RGD:5147779 RGD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link IEP 2 212,277,654 212,297,376 RGD:7240511 RGD
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Path 1
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  Diseases 30466
    Bacterial Infections and Mycoses 1471
      Bacterial Infections 522
        Bacteremia 89
          Endotoxemia 83
Path 2
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  Diseases 30466
    Pathological Conditions, Signs and Symptoms 5122
      Pathologic Processes 2190
        Inflammation 381
          Systemic Inflammatory Response Syndrome 243
            Sepsis 236
              Bacteremia 89
                Endotoxemia 83
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