Myocardial Reperfusion Injury - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	Myocardial Reperfusion Injury	go back to main search page
Accession:	RDO:0006866	browse the term
Definition:	Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
Synonyms:	exact_synonym:	Myocardial Ischemic Reperfusion Injury; Myocardial Reperfusion Injuries
	primary_id:	MESH:D015428

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Myocardial Reperfusion Injury
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8			ISS	11	17,414,432	17,498,449	RGD:2301903	RGD
G	ACTC1	actin, alpha, cardiac muscle 1		Induced	ISS	15	35,080,297	35,087,927	RGD:1598727	RGD
G	ADA	adenosine deaminase			ISS	20	43,248,163	43,280,376	RGD:1624305	RGD
G	ADRB1	adrenoceptor beta 1			ISS	10	115,803,806	115,806,667	RGD:5129149	RGD
G	ADRB2	adrenoceptor beta 2, surface			ISS	5	148,206,156	148,208,197	RGD:1598746	RGD
G	AGER	advanced glycosylation end product-specific receptor			ISS	6	32,148,745	32,152,099	RGD:1625342	RGD
G	AGL	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase		Induced	IED	1	100,315,640	100,389,579	RGD:1598779	RGD
G	AGTR1	angiotensin II receptor, type 1			ISS	3	148,415,658	148,460,790	RGD:5129194	RGD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1			ISS	14	105,235,686	105,262,080	RGD:5509104	RGD
G	AKT2	v-akt murine thymoma viral oncogene homolog 2			ISS	19	40,736,224	40,791,302	RGD:2313347	RGD
G	ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)			ISS	12	112,204,691	112,247,789	RGD:7241598	RGD
G	ALOX5	arachidonate 5-lipoxygenase			ISS	10	45,869,624	45,941,567	RGD:2317527	RGD
G	ANGPT2	angiopoietin 2			ISS	8	6,357,172	6,420,784	RGD:1601505	RGD
G	ANK1	ankyrin 1, erythrocytic			ISS	8	41,510,744	41,754,280	RGD:1599110	RGD
G	ANK2	ankyrin 2, neuronal			ISS	4	113,739,239	114,304,896	RGD:1599110	RGD
G	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)			ISS	10	92,671,857	92,681,032	RGD:5133278	RGD
G	ANXA1	annexin A1			ISS	9	75,766,781	75,785,307	RGD:2306910	RGD
G	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1			ISS	14	20,923,290	20,925,931	RGD:2315672	RGD
G	BAD	BCL2-associated agonist of cell death			ISS	11	64,037,300	64,052,176	RGD:2292700	RGD
G	BCL2	B-cell CLL/lymphoma 2			ISS	18	60,790,579	60,986,613	RGD:1599484	RGD
G	BID	BH3 interacting domain death agonist			ISS	22	18,216,906	18,257,431	RGD:2317561	RGD
G	BLK	B lymphoid tyrosine kinase			ISS	8	11,351,521	11,422,108	RGD:1642307	RGD
G	BTG2	BTG family, member 2			ISS	1	203,274,664	203,278,730	RGD:2289075	RGD
G	C3	complement component 3			ISS	19	6,677,846	6,720,662	RGD:1582136	RGD
G	C5	complement component 5			ISS	9	123,714,613	123,812,554	RGD:1600666	RGD
G	CASP12	caspase 12 (gene/pseudogene)			ISS	11	104,756,445	104,769,397	RGD:2311458	RGD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase			ISS	4	185,548,850	185,570,629	RGD:2293314	RGD
G	CASR	calcium-sensing receptor			ISS	3	121,902,530	122,005,344	RGD:7205698	RGD
G	CAST	calpastatin			ISS	5	95,997,741	96,110,387	RGD:5683872	RGD
G	CAT	catalase			ISS	11	34,460,472	34,493,607	RGD:1581149	RGD
G	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)			IEP	3	46,411,633	46,417,697	RGD:4892017	RGD
G	CNR1	cannabinoid receptor 1 (brain)			ISS	6	88,849,583	88,875,767	RGD:2316217	RGD
G	CNR2	cannabinoid receptor 2 (macrophage)			ISS	1	24,200,460	24,239,817	RGD:2316224	RGD
G	CRP	C-reactive protein, pentraxin-related			ISS	1	159,682,079	159,684,379	RGD:5128547	RGD
G	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)			ISS	4	74,735,109	74,737,019	RGD:5135269	RGD
G	CXCL2	chemokine (C-X-C motif) ligand 2			ISS	4	74,962,752	74,964,997	RGD:5135269	RGD
G	CXCL5	chemokine (C-X-C motif) ligand 5			ISS	4	74,861,359	74,864,416	RGD:5135269	RGD
G	DCN	decorin			ISS	12	91,539,035	91,576,806	RGD:1598727	RGD
G	EDN1	endothelin 1			ISS	6	12,290,529	12,297,427	RGD:4892580	RGD
G	EDNRA	endothelin receptor type A			ISS	4	148,402,069	148,466,106	RGD:4892580	RGD
G	EDNRB	endothelin receptor type B			ISS	13 13	78,469,616 78,513,393	78,549,664 78,549,674	RGD:4892332	RGD
G	ESR1	estrogen receptor 1			ISS	6	152,011,631	152,424,409	RGD:4892299	RGD
G	ESR2	estrogen receptor 2 (ER beta)			ISS	14	64,693,751	64,805,268	RGD:5508820	RGD
G	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)			ISS	14	62,162,119	62,214,977	RGD:1626327	RGD
G	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)			ISS	14	62,162,119	62,214,977	RGD:5147885	RGD
G	HMOX1	heme oxygenase (decycling) 1			ISS	22	35,777,060	35,790,207	RGD:1582708	RGD
G	HMOX1	heme oxygenase (decycling) 1			ISS	22	35,777,060	35,790,207	RGD:1598392	RGD
G	HRH3	histamine receptor H3			ISS	20	60,790,017	60,795,323	RGD:1626433	RGD
G	HSPA8	heat shock 70kDa protein 8			ISS	11	122,928,200	122,932,901	RGD:6480208	RGD
G	HTRA2	HtrA serine peptidase 2			ISS	2	74,756,532	74,760,683	RGD:5688376	RGD
G	ICAM1	intercellular adhesion molecule 1			ISS	19	10,381,517	10,397,291	RGD:4145348	RGD
G	IL10	interleukin 10			ISS	1	206,940,948	206,945,839	RGD:2311056	RGD
G	IL18	interleukin 18 (interferon-gamma-inducing factor)			ISS	11	112,013,974	112,034,840	RGD:4889400	RGD
G	IL18	interleukin 18 (interferon-gamma-inducing factor)			ISS	11	112,013,974	112,034,840	RGD:4889578	RGD
G	IL18BP	interleukin 18 binding protein			ISS	11	71,709,958	71,713,965	RGD:4889578	RGD
G	IL18BP	interleukin 18 binding protein			IED	11	71,709,958	71,713,965	RGD:4889400	RGD
G	IL18RAP	interleukin 18 receptor accessory protein			ISS	2	103,035,254	103,069,025	RGD:4889578	RGD
G	IL1B	interleukin 1, beta			ISS	2	113,587,337	113,594,356	RGD:1626628	RGD
G	IL1RN	interleukin 1 receptor antagonist			IED	2	113,875,470	113,891,593	RGD:7174360	RGD
G	IL6R	interleukin 6 receptor			IED	1	154,377,669	154,441,926	RGD:1625435	RGD
G	IRAK1	interleukin-1 receptor-associated kinase 1			ISS	X	153,275,957	153,285,342	RGD:1579809	RGD
G	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8			ISS	12	21,917,889	21,927,755	RGD:729109	RGD
G	LEP	leptin			ISS	7	127,881,331	127,897,682	RGD:5128547	RGD
G	LEPR	leptin receptor			ISS	1	65,886,335	66,103,176	RGD:5129123	RGD
G	LUM	lumican			ISS	12	91,497,232	91,505,542	RGD:1582122	RGD
G	MAP2K6	mitogen-activated protein kinase kinase 6		Induced	ISS	17	67,410,838	67,538,470	RGD:1582277	RGD
G	MAPK1	mitogen-activated protein kinase 1			ISS	22	22,113,946	22,221,970	RGD:1582282	RGD
G	MAPK8	mitogen-activated protein kinase 8		Model	ISS	10	49,609,687	49,643,183	RGD:1582311	RGD
G	MB	myoglobin		Model	ISS	22	36,002,811	36,019,401	RGD:1582385	RGD
G	MDM2	MDM2 oncogene, E3 ubiquitin protein ligase			ISS	12	69,201,971	69,239,320	RGD:2317401	RGD
G	MKI67	antigen identified by monoclonal antibody Ki-67			ISS	10	129,894,923	129,924,468	RGD:6483543	RGD
G	MMP1	matrix metallopeptidase 1 (interstitial collagenase)			IED	11	102,660,641	102,668,966	RGD:1582539	RGD
G	MMP1	matrix metallopeptidase 1 (interstitial collagenase)			ISS	11	102,660,641	102,668,966	RGD:7207397	RGD
G	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)		Induced	ISS	16	55,513,081	55,540,586	RGD:1582614	RGD
G	MYD88	myeloid differentiation primary response 88			ISS	3	38,179,969	38,184,513	RGD:1302746	RGD
G	NOS2	nitric oxide synthase 2, inducible			ISS	17	26,083,792	26,127,555	RGD:5509098	RGD
G	NOS3	nitric oxide synthase 3 (endothelial cell)			ISS	7	150,688,144	150,711,687	RGD:2292091	RGD
G	NOS3	nitric oxide synthase 3 (endothelial cell)			ISS	7	150,688,144	150,711,687	RGD:4891991	RGD
G	NPPB	natriuretic peptide B			ISS	1	11,917,521	11,918,992	RGD:5685663	RGD
G	NPPC	natriuretic peptide C			ISS	2	232,786,805	232,791,038	RGD:1580149	RGD
G	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)			ISS	5	32,710,743	32,791,830	RGD:1580149	RGD
G	NPY1R	neuropeptide Y receptor Y1			ISS	4	164,245,117	164,253,947	RGD:1642307	RGD
G	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1			ISS	12	10,310,899	10,324,790	RGD:628368	RGD
G	OPRD1	opioid receptor, delta 1			ISS	1	29,138,654	29,190,208	RGD:2316590	RGD
G	OXT	oxytocin/neurophysin I prepropeptide			ISS	20	3,052,266	3,053,162	RGD:2304087	RGD
G	P2RY12	purinergic receptor P2Y, G-protein coupled, 12			IPM	3	151,055,376	151,102,544	RGD:6480645	RGD
G	PARP1	poly (ADP-ribose) polymerase 1			ISS	1	226,548,392	226,595,801	RGD:5683917	RGD
G	PECAM1	platelet/endothelial cell adhesion molecule 1			ISS	17	62,396,775	62,404,856	RGD:2311662	RGD
G	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma			ISS	7	106,505,924	106,547,592	RGD:6482687	RGD
G	PLCD1	phospholipase C, delta 1			ISS	3	38,048,987	38,071,154	RGD:1304368	RGD
G	PLD2	phospholipase D2			ISS	17	4,710,396	4,726,727	RGD:2299906	RGD
G	PPARD	peroxisome proliferator-activated receptor delta			ISS	6	35,310,335	35,395,968	RGD:2324876	RGD
G	PPARG	peroxisome proliferator-activated receptor gamma			ISS	3	12,329,349	12,475,855	RGD:2301853	RGD
G	PRKCB	protein kinase C, beta			ISS	16	23,847,300	24,231,932	RGD:1625520	RGD
G	PRKCD	protein kinase C, delta			ISS	3	53,195,223	53,226,733	RGD:1642542	RGD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)			ISS	1	186,640,944	186,649,559	RGD:2300261	RGD
G	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)			ISS	11	65,421,067	65,430,443	RGD:2298773	RGD
G	RHOA	ras homolog family member A			ISS	3	49,396,578	49,449,526	RGD:1642967	RGD
G	S100B	S100 calcium binding protein B			ISS	21	48,018,531	48,025,035	RGD:5508825	RGD
G	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)			ISS	1	169,558,087	169,599,377	RGD:6480105	RGD
G	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3			IPM	14	95,078,714	95,090,390	RGD:5147423	RGD
G	SFRP2	secreted frizzled-related protein 2			ISS	4	154,701,742	154,710,228	RGD:4107088	RGD
G	SHH	sonic hedgehog			ISS	7	155,595,558	155,604,967	RGD:2306299	RGD
G	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1			ISS	2	40,339,286	40,739,575	RGD:1642729	RGD
G	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1			ISS	2	40,339,286	40,739,575	RGD:1642716	RGD
G	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1			ISS	1	27,425,300	27,481,621	RGD:6771238	RGD
G	SMAD1	SMAD family member 1			IED	4	146,402,951	146,480,328	RGD:1643233	RGD
G	SOD2	superoxide dismutase 2, mitochondrial			ISS	6	160,100,148	160,114,353	RGD:1581222	RGD
G	SORD	sorbitol dehydrogenase			ISS	15	45,315,302	45,367,287	RGD:1601364	RGD
G	SPP1	secreted phosphoprotein 1			ISS	4	88,896,802	88,904,563	RGD:1581342	RGD
G	STAT1	signal transducer and activator of transcription 1, 91kDa			ISS	2	191,833,762	191,878,976	RGD:1600091	RGD
G	TEK	TEK tyrosine kinase, endothelial			ISS	9	27,109,147	27,230,172	RGD:1601505	RGD
G	THBS1	thrombospondin 1			ISS	15	39,873,280	39,889,668	RGD:2317960	RGD
G	TIMP4	TIMP metallopeptidase inhibitor 4			ISS	3	12,194,568	12,200,851	RGD:2290461	RGD
G	TLR2	toll-like receptor 2			ISS	4	154,605,441	154,627,243	RGD:2312688	RGD
G	TLR4	toll-like receptor 4			ISS	9	120,466,453	120,479,769	RGD:1302746	RGD
G	TNC	tenascin C			ISS	9	117,781,854	117,880,536	RGD:4889599	RGD
G	TP53	tumor protein p53			ISS	17	7,571,720	7,590,868	RGD:2290554	RGD
G	TXN	thioredoxin			ISS	9	113,006,092	113,018,920	RGD:2306159	RGD
G	TXN2	thioredoxin 2			ISS	22	36,863,093	36,877,687	RGD:2306159	RGD
G	UCN	urocortin			ISS	2	27,530,265	27,531,130	RGD:1642783	RGD
G	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)			ISS	11	73,685,716	73,693,889	RGD:2313528	RGD
G	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)			ISS	11	73,711,326	73,720,282	RGD:2313528	RGD
G	UTS2	urotensin 2			ISS	1	7,907,672	7,913,551	RGD:2306836	RGD
G	UTS2R	urotensin 2 receptor			ISS	17	80,332,201	80,333,370	RGD:2306836	RGD
G	VCAM1	vascular cell adhesion molecule 1			ISS	1	101,185,196	101,204,601	RGD:7207792	RGD

Term paths to the root

Path 1
Term	Annotations
Diseases	29328
Cardiovascular Diseases	4489
Heart Diseases	1950
Cardiomyopathies	531
Myocardial Reperfusion Injury	126
Path 2
Term	Annotations
Diseases	29328
Pathological Conditions, Signs and Symptoms	5330
Pathologic Processes	2117
Postoperative Complications	546
Reperfusion Injury	523
Myocardial Reperfusion Injury	126