ONTOLOGY REPORT - ANNOTATIONS

Term:Lung Injury
go back to main search page
Accession:RDO:0006082 term browser browse the term
Definition:Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.
Synonyms:exact_synonym: Chronic Lung Injuries;   Chronic Lung Injury;   Lung Injuries;   Pulmonary Injuries;   Pulmonary Injury
 primary_id: MESH:D055370

  • Rat
  • Mouse
  • Human
  • All
  • show annotations for term's descendants
  •     Sort by:
Lung Injury term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cxcr3 chemokine (C-X-C motif) receptor 3 GBrowse link ISS X 89,794,276 89,796,927 RGD:5135486 RGD
G Esr2 estrogen receptor 2 (ER beta) GBrowse link IED 6 98,691,167 98,775,299 RGD:4892252 RGD
G Igf2 insulin-like growth factor 2 GBrowse link IEP 1 202,906,624 202,915,231 RGD:5509974 RGD
G Ltf lactotransferrin GBrowse link ISS 8 115,417,764 115,440,609 RGD:7243109 RGD
G Mt2A metallothionein 2A GBrowse link ISS 19 11,267,811 11,268,585 RGD:6483842 RGD
G Ngf nerve growth factor (beta polypeptide) GBrowse link ISS 2 197,621,726 197,632,960 RGD:5144062 RGD
G Ngfr nerve growth factor receptor GBrowse link ISS 10 84,262,804 84,281,006 RGD:5144065 RGD
G Pecam1 platelet/endothelial cell adhesion molecule 1 GBrowse link ISS 10 96,056,220 96,057,232 RGD:6771215 RGD
G Plau plasminogen activator, urokinase GBrowse link IEP 15 3,680,072 3,686,232 RGD:4143526 RGD
G Plaur plasminogen activator, urokinase receptor GBrowse link ISS 1 79,708,646 79,712,881 RGD:6483820 RGD
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 GBrowse link ISS 7 139,094,505 139,127,427 RGD:5688724 RGD
G Tacr1 tachykinin receptor 1 GBrowse link ISS 4 116,610,595 116,780,394 RGD:5147820 RGD
Acute Lung Injury term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link ISS 11 79,908,291 79,911,065 RGD:5686380 RGD
G Adra2a adrenoceptor alpha 2A IEP RGD:6480481 RGD
G Alb albumin GBrowse link IED 14 19,126,935 19,142,214 RGD:6483494 RGD
G Alox15 arachidonate 15-lipoxygenase GBrowse link ISS 10 57,185,939 57,194,388 RGD:5509626 RGD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link IEP 10 70,256,263 70,258,061 RGD:6480432 RGD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link ISS 10 71,759,643 71,761,115 RGD:5683874 RGD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link IPM 10 71,759,643 71,761,115 RGD:68880 RGD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link IEP 10 71,759,643 71,761,115 RGD:6480432 RGD
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link ISS 8 128,693,658 128,699,213 RGD:5688151 RGD
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link ISS 4 13,471,878 13,525,620 RGD:6893505 RGD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link ISS 14 18,690,339 18,692,118 RGD:5135253 RGD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link ISS 14 18,677,129 18,679,175 RGD:5135247 RGD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link ISS 14 18,677,129 18,679,175 RGD:5135253 RGD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link IEP 14 18,677,129 18,679,175 RGD:5147925 RGD
G Cxcl5 chemokine (C-X-C motif) ligand 5 GBrowse link ISS 14 18,825,357 18,826,269 RGD:5135247 RGD
G Cxcl5 chemokine (C-X-C motif) ligand 5 GBrowse link IPM 14 18,825,357 18,826,269 RGD:5135256 RGD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link ISS 8 61,462,207 61,468,237 RGD:5135235 RGD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link IEP 8 61,462,207 61,468,237 RGD:5147744 RGD
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 GBrowse link IEP 1 81,266,828 81,290,471 RGD:5147744 RGD
G Ephx2 epoxide hydrolase 2, cytoplasmic GBrowse link IED 15 45,497,660 45,556,101 RGD:5688354 RGD
G Fcgr1a Fc fragment of IgG, high affinity Ia, receptor (CD64) GBrowse link IPM 2 191,095,026 191,103,942 RGD:5147925 RGD
G Fcgr2a Fc fragment of IgG, low affinity IIa, receptor GBrowse link IPM 13 86,898,651 86,911,743 RGD:5147925 RGD
G Flt1 FMS-related tyrosine kinase 1 GBrowse link IPM 12 7,858,092 8,035,966 RGD:5684427 RGD
G Gzmb granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) GBrowse link ISS 15 35,195,075 35,198,506 RGD:5135517 RGD
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link ISS 2 27,127,504 27,149,580 RGD:5508470 RGD
G Ifng interferon gamma GBrowse link IEP 7 57,621,756 57,625,792 RGD:6480432 RGD
G Il1b interleukin 1 beta GBrowse link IED 3 116,964,422 116,970,867 RGD:7204498 RGD
G Il1b interleukin 1 beta GBrowse link IEP 3 116,964,422 116,970,867 RGD:4143193 RGD
G Il1b interleukin 1 beta GBrowse link ISS 3 116,964,422 116,970,867 RGD:4142807 RGD
G Il1b interleukin 1 beta GBrowse link IEP 3 116,964,422 116,970,867 RGD:4142531 RGD
G Il1b interleukin 1 beta GBrowse link IEP 3 116,964,422 116,970,867 RGD:6480432 RGD
G Il1rl1 interleukin 1 receptor-like 1 GBrowse link ISS 9 39,577,879 39,624,781 RGD:5144222 RGD
G Il2 interleukin 2 GBrowse link IEP 2 123,655,005 123,659,709 RGD:6480432 RGD
G Il22 interleukin 22 GBrowse link ISS 7 57,517,321 57,521,786 RGD:4888524 RGD
G Itgb2 integrin, beta 2 GBrowse link IPM 20 11,446,521 11,485,009 RGD:6482199 RGD
G Kdr kinase insert domain receptor IEP RGD:5684427 RGD
G Mpo myeloperoxidase GBrowse link ISS 10 76,085,872 76,097,012 RGD:6909173 RGD
G Ngf nerve growth factor (beta polypeptide) GBrowse link ISS 2 197,621,726 197,632,960 RGD:5144065 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IPM 10 65,036,884 65,072,453 RGD:5147744 RGD
G P2ry12 purinergic receptor P2Y, G-protein coupled, 12 GBrowse link IPM 2 148,611,035 148,613,985 RGD:6480522 RGD
G Pecam1 platelet/endothelial cell adhesion molecule 1 GBrowse link IED 10 96,056,220 96,057,232 RGD:6483494 RGD
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma GBrowse link ISS 6 50,441,892 50,476,931 RGD:6482677 RGD
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) GBrowse link Severity IEP 5 157,654,786 157,657,360 RGD:6482722 RGD
G Plau plasminogen activator, urokinase GBrowse link IED 15 3,680,072 3,686,232 RGD:5147760 RGD
G Plau plasminogen activator, urokinase GBrowse link Treatment IED 15 3,680,072 3,686,232 RGD:7241552 RGD
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link ISS 2 54,327,821 54,360,462 RGD:6484539 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link IEP 13 64,427,288 64,432,978 RGD:5135496 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link ISS 13 64,427,288 64,432,978 RGD:5135287 RGD
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) GBrowse link IEP 1 211,758,103 211,761,651 RGD:5143982 RGD
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) GBrowse link ISS 1 211,758,103 211,761,651 RGD:5144142 RGD
G Tac1 tachykinin, precursor 1 GBrowse link ISS 4 32,649,666 32,657,632 RGD:5147812 RGD
G Tacr1 tachykinin receptor 1 GBrowse link ISS 4 116,610,595 116,780,394 RGD:5147819 RGD
G Thbd thrombomodulin GBrowse link ISS 3 137,158,955 137,162,607 RGD:5131887 RGD
G Thbd thrombomodulin GBrowse link ISS 3 137,158,955 137,162,607 RGD:5685372 RGD
G Tlr4 toll-like receptor 4 GBrowse link IEP 5 83,564,100 83,577,735 RGD:5135496 RGD
G Tnf tumor necrosis factor GBrowse link IEP 20 3,661,000 3,663,618 RGD:6480432 RGD
G Tnf tumor necrosis factor GBrowse link IEP 20 3,661,000 3,663,618 RGD:5147925 RGD
G Vegfa vascular endothelial growth factor A GBrowse link IEP 9 10,520,730 10,536,071 RGD:5684427 RGD
G Vip vasoactive intestinal peptide GBrowse link IED 1 36,361,513 36,369,594 RGD:4145303 RGD
Asbestosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Clca1 chloride channel accessory 1 GBrowse link ISS 2 243,057,135 243,084,146 RGD:4145655 RGD
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 GBrowse link ISS 1 200,918,521 200,928,919 RGD:4892076 RGD
G Ephx1 epoxide hydrolase 1, microsomal (xenobiotic) GBrowse link Susceptibility ISS 13 96,722,973 96,752,940 RGD:4889408 RGD
G Gstm1 glutathione S-transferase mu 1 GBrowse link Susceptibility ISS 2 203,575,444 203,580,821 RGD:5490588 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link ISS 10 65,036,884 65,072,453 RGD:4891441 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IEP 10 65,036,884 65,072,453 RGD:4891438 RGD
G Tnc tenascin C ISS RGD:4889594 RGD
Berylliosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link Disease_progression ISS 8 128,907,157 128,912,272 RGD:4892065 RGD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link ISS 19 13,963,139 13,969,960 RGD:4145349 RGD
G Tgfb1 transforming growth factor, beta 1 GBrowse link Severity ISS 1 80,894,705 80,911,020 RGD:4145294 RGD
Bronchopulmonary Dysplasia term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cat catalase GBrowse link IED 3 88,654,077 88,686,212 RGD:5130750 RGD
G Ccl7 chemokine (C-C motif) ligand 7 GBrowse link ISS 10 70,267,281 70,269,131 RGD:5130981 RGD
G Cd209c CD209c molecule GBrowse link ISS 12 2,236,285 2,244,559 RGD:5131185 RGD
G Chi3l1 chitinase 3-like 1 (cartilage glycoprotein-39) GBrowse link ISS 13 47,139,658 47,147,591 RGD:4892651 RGD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link IEP 14 18,690,339 18,692,118 RGD:5134972 RGD
G Edn1 endothelin 1 GBrowse link IEP 17 28,303,886 28,309,775 RGD:4144841 RGD
G Gstp1 glutathione S-transferase pi 1 GBrowse link Susceptibility ISS 1 206,627,398 206,629,866 RGD:4142520 RGD
G Il1b interleukin 1 beta GBrowse link ISS 3 116,964,422 116,970,867 RGD:4143172 RGD
G Il1rn interleukin 1 receptor antagonist GBrowse link ISS 3 2,607,800 2,613,216 RGD:4143172 RGD
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link ISS 20 13,191,986 13,192,851 RGD:4891007 RGD
G Mmp9 matrix metallopeptidase 9 GBrowse link ISS 3 155,985,473 155,993,433 RGD:5129685 RGD
G Muc1 mucin 1, cell surface associated GBrowse link Severity ISS 2 181,399,482 181,403,640 RGD:5131170 RGD
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) GBrowse link ISS 1 211,758,103 211,761,651 RGD:5144211 RGD
G Sftpa1 surfactant protein A1 GBrowse link ISS 16 17,570,887 17,574,389 RGD:4143384 RGD
G Sftpa1 surfactant protein A1 GBrowse link Susceptibility ISS 16 17,570,887 17,574,389 RGD:4144876 RGD
G Sftpb surfactant protein B GBrowse link ISS 4 105,609,410 105,618,452 RGD:4143405 RGD
G Sftpb surfactant protein B GBrowse link Susceptibility ISS 4 105,609,410 105,618,452 RGD:4143418 RGD
G Sftpb surfactant protein B GBrowse link ISS 4 105,609,410 105,618,452 RGD:4143384 RGD
G Sftpd surfactant protein D ISS RGD:4143384 RGD
Lung Reperfusion Injury term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Il1b interleukin 1 beta GBrowse link IED 3 116,964,422 116,970,867 RGD:7183185 RGD
G Il1b interleukin 1 beta GBrowse link IEP 3 116,964,422 116,970,867 RGD:7204125 RGD
G Myc myelocytomatosis oncogene GBrowse link Treatment IED 7 98,953,142 98,958,060 RGD:7240537 RGD
G Pecam1 platelet/endothelial cell adhesion molecule 1 GBrowse link IED 10 96,056,220 96,057,232 RGD:6771212 RGD
Meconium Aspiration Syndrome term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) GBrowse link ISS 1 211,758,103 211,761,651 RGD:5144123 RGD
Pneumoconiosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cat catalase GBrowse link ISS 3 88,654,077 88,686,212 RGD:5130756 RGD
Pneumonia, Ventilator-Associated term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Gc group specific component GBrowse link ISS 14 20,166,243 20,197,060 RGD:5509873 RGD
Radiation Pneumonitis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Alox5 arachidonate 5-lipoxygenase GBrowse link IPM 4 152,610,283 152,657,891 RGD:4890434 RGD
G C3 complement component 3 ISS RGD:5129484 RGD
G C4bpa complement component 4 binding protein, alpha GBrowse link ISS 13 43,552,947 43,588,565 RGD:5129484 RGD
G Ccl17 chemokine (C-C motif) ligand 17 GBrowse link IEP 19 10,641,376 10,642,827 RGD:4145517 RGD
G Ccl22 chemokine (C-C motif) ligand 22 GBrowse link IEP 19 10,697,324 10,704,129 RGD:4145517 RGD
G Il13 interleukin 13 GBrowse link Susceptibility ISS 10 39,093,512 39,096,069 RGD:5131286 RGD
G Il1a interleukin 1 alpha GBrowse link Susceptibility ISS 3 116,913,612 116,924,114 RGD:5131286 RGD
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link Susceptibility ISS 20 13,191,986 13,192,851 RGD:5131286 RGD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link Susceptibility ISS 4 6,158,847 6,179,441 RGD:5131286 RGD
G Sftpd surfactant protein D Susceptibility ISS RGD:4143486 RGD
G Tgfb1 transforming growth factor, beta 1 GBrowse link ISS 1 80,894,705 80,911,020 RGD:4145121 RGD
G Tgfb1 transforming growth factor, beta 1 GBrowse link IPM 1 80,894,705 80,911,020 RGD:4145278 RGD
G Tgfb1 transforming growth factor, beta 1 GBrowse link Susceptibility ISS 1 80,894,705 80,911,020 RGD:4145136 RGD
G Tnf tumor necrosis factor GBrowse link Susceptibility ISS 20 3,661,000 3,663,618 RGD:5131286 RGD
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a GBrowse link ISS 4 162,172,563 162,185,252 RGD:5131153 RGD
G Vtn vitronectin GBrowse link ISS 10 64,609,242 64,612,322 RGD:5129484 RGD
S WAG/RijCmcr Induced IED RGD:2303635 RGD
Silicosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Arg1 arginase, liver GBrowse link IEP 1 20,998,894 21,011,275 RGD:4143368 RGD
G C3 complement component 3 ISS RGD:5129516 RGD
G Ccl7 chemokine (C-C motif) ligand 7 GBrowse link IEP 10 70,267,281 70,269,131 RGD:6483764 RGD
G Chia chitinase, acidic GBrowse link IEP 2 201,385,584 201,431,777 RGD:4893904 RGD
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 GBrowse link ISS 9 59,495,773 59,501,300 RGD:4891515 RGD
G Egr1 early growth response 1 GBrowse link IEP 18 27,343,919 27,346,117 RGD:5131937 RGD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link ISS 19 13,963,139 13,969,960 RGD:4145384 RGD
G Il17a interleukin 17A GBrowse link ISS 9 19,454,979 19,458,467 RGD:4888525 RGD
G Il1rn interleukin 1 receptor antagonist GBrowse link Susceptibility ISS 3 2,607,800 2,613,216 RGD:4142816 RGD
G Il2ra interleukin 2 receptor, alpha GBrowse link ISS 17 78,050,491 78,097,802 RGD:4891500 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link ISS 10 65,036,884 65,072,453 RGD:4891445 RGD
G Prkcb protein kinase C, beta GBrowse link IED 1 181,117,512 181,459,856 RGD:1625527 RGD
G Tnf tumor necrosis factor GBrowse link ISS 20 3,661,000 3,663,618 RGD:4142816 RGD
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a GBrowse link ISS 4 162,172,563 162,185,252 RGD:5131150 RGD
Ventilator-Induced Lung Injury term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link ISS 6 137,640,482 137,657,552 RGD:5509080 RGD
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide GBrowse link IPM 13 88,258,993 88,283,918 RGD:6903342 RGD
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link ISS 4 96,649,941 96,652,243 RGD:5509080 RGD
G Il1b interleukin 1 beta GBrowse link IED 3 116,964,422 116,970,867 RGD:6482672 RGD
G Il1b interleukin 1 beta GBrowse link ISS 3 116,964,422 116,970,867 RGD:4142534 RGD
G Il1b interleukin 1 beta GBrowse link IPM 3 116,964,422 116,970,867 RGD:4142537 RGD
G Il1r1 interleukin 1 receptor, type I GBrowse link IPM 9 39,434,910 39,473,552 RGD:2311107 RGD
G Il1rn interleukin 1 receptor antagonist GBrowse link IEP 3 2,607,800 2,613,216 RGD:6909178 RGD
G Il22 interleukin 22 GBrowse link ISS 7 57,517,321 57,521,786 RGD:5147406 RGD
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma GBrowse link ISS 6 50,441,892 50,476,931 RGD:6482697 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link IPM 13 64,427,288 64,432,978 RGD:5134956 RGD
G Scgb1a1 secretoglobin, family 1A, member 1 (uteroglobin) GBrowse link ISS 1 211,758,103 211,761,651 RGD:5144143 RGD
G Tacr1 tachykinin receptor 1 GBrowse link IPM 4 116,610,595 116,780,394 RGD:5147811 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  Diseases 30477
    Wounds and Injuries 676
      Thoracic Injuries 153
        Lung Injury 151
          Acute Lung Injury 59
          Lung Reperfusion Injury + 4
          Meconium Aspiration Syndrome 1
          Pneumoconiosis + 25
          Radiation Pneumonitis 17
          Ventilator-Induced Lung Injury + 33
paths to the root

Contact Us |  About Us |  Jobs at RGD