Glioblastoma - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:	Glioblastoma	go back to main search page
Accession:	RDO:0005677	browse the term
Definition:	A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
Synonyms:	exact_synonym:	Giant Cell Glioblastoma; Giant Cell Glioblastomas; Glioblastoma Multiforme; Glioblastomas; Grade IV Astrocytoma; Grade IV Astrocytomas
	primary_id:	MESH:D005909
	alt_id:	OMIM:600259

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Glioblastoma
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Akt1	v-akt murine thymoma viral oncogene homolog 1			ISS	6	137,640,482	137,657,552	RGD:734543	RGD
G	Becn1	beclin 1, autophagy related		Disease_progression	ISS	10	90,317,957	90,333,329	RGD:6483102	RGD
G	Chi3l1	chitinase 3-like 1 (cartilage glycoprotein-39)			ISS	13	47,139,658	47,147,591	RGD:4892621	RGD
G	Ctsb	cathepsin B			ISS	15	42,402,829	42,423,701	RGD:2315515	RGD
G	Ctsh	cathepsin H			ISS	8	94,971,689	94,990,434	RGD:1549417	RGD
G	Dmbt1	deleted in malignant brain tumors 1			ISS	1	190,378,428	190,470,536	RGD:1599778	RGD
G	F2	coagulation factor II			ISS	3	76,005,318	76,018,603	RGD:1578509	RGD
G	Fabp7	fatty acid binding protein 7, brain			ISS	20	36,812,518	36,816,050	RGD:1578468	RGD
G	Il16	interleukin 16			IEP	1	139,908,061	140,000,146	RGD:5024941	RGD
G	L1cam	L1 cell adhesion molecule			ISS	X	159,784,792	159,801,553	RGD:6483067	RGD
G	Map2k3	mitogen activated protein kinase kinase 3		Disease_progression	ISS	10	47,075,270	47,096,617	RGD:1641940	RGD
G	Mgmt	O-6-methylguanine-DNA methyltransferase			ISS	1	196,629,366	196,866,937	RGD:2317667	RGD
G	Mmp2	matrix metallopeptidase 2		Severity	ISS	19	15,246,036	15,275,061	RGD:7207145	RGD
G	Mmp7	matrix metallopeptidase 7		Severity	ISS	8	4,526,018	4,533,730	RGD:7207145	RGD
G	Mmp9	matrix metallopeptidase 9		Severity	ISS	3	155,985,473	155,993,433	RGD:7207145	RGD
G	Pdpn	podoplanin			ISS	5	162,142,251	162,175,921	RGD:2292241	RGD
G	Pecam1	platelet/endothelial cell adhesion molecule 1			ISS	10	96,056,220	96,057,232	RGD:6771207	RGD
G	Pgf	placental growth factor		Disease_progression	ISS	6	109,215,540	109,226,122	RGD:6483585	RGD
G	Pms2	postmeiotic segregation increased 2 (S. cerevisiae)			ISS	12	11,004,507	11,028,754	RGD:7240710	OMIM
G	Pten	phosphatase and tensin homolog			ISS	1	236,771,027	236,837,261	RGD:2290476	RGD
G	Ptgs1	prostaglandin-endoperoxide synthase 1			IEP	3	15,343,832	15,365,412	RGD:5688250	RGD
G	Ptgs1	prostaglandin-endoperoxide synthase 1		Disease_progression	ISS	3	15,343,832	15,365,412	RGD:5688245	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2			IEP	13	64,427,288	64,432,978	RGD:5688250	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		Disease_progression	ISS	13	64,427,288	64,432,978	RGD:5688245	RGD
G	Tnc	tenascin C			ISS				RGD:4889612	RGD
G	Yeats4	YEATS domain containing 4			ISS	7	56,559,308	56,566,449	RGD:704404	RGD
S	ACI/N	A X C 9935, Irish			TAS				RGD:1004	RGD

Term paths to the root

Path 1
Term	Annotations
Diseases	30477
Neoplasms	5210
Neoplasms by Histologic Type	1784
Neoplasms, Glandular and Epithelial	1129
Neoplasms, Neuroepithelial	124
Glioma	104
Astrocytoma	38
Glioblastoma	27
Path 2
Term	Annotations
Diseases	30477
Neoplasms	5210
Neoplasms by Histologic Type	1784
Neoplasms, Germ Cell and Embryonal	308
Neuroectodermal Tumors	198
Neoplasms, Neuroepithelial	124
Glioma	104
Astrocytoma	38
Glioblastoma	27