ONTOLOGY REPORT - ANNOTATIONS

Term:Leukemia, Myeloid, Acute
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Accession:RDO:0005531 term browser browse the term
Definition:Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
Synonyms:exact_synonym: ACUTE MYELOID LEUKEMIA CHROMOSOME REGION 2;   AML;   AMLCR2;   ANLL;   Acute Myeloblastic Leukemia;   Acute Myeloblastic Leukemias;   Acute Myelocytic Leukemia;   Acute Myelocytic Leukemias;   Acute Myelogenous Leukemia;   Acute Myelogenous Leukemias;   Acute Myeloid Leukemia with Maturation;   Acute Myeloid Leukemia without Maturation;   Acute Myeloid Leukemias;   Acute Nonlymphoblastic Leukemia;   Acute Nonlymphoblastic Leukemias;   Acute Nonlymphocytic Leukemia;   Acute Nonlymphocytic Leukemias;   LEUKEMIA, ACUTE MYELOGENOUS LEUKEMIA, ACUTE MYELOID, SUSCEPTIBILITY TO;   Myeloid Leukemia, Acute, M1;   Myeloid Leukemia, Acute, M2
 primary_id: MESH:D015470
 alt_id: OMIM:121360;   OMIM:601626;   OMIM:602439

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Leukemia, Myeloid, Acute term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 GBrowse link ISS 8 45,984,042 46,106,412 RGD:7240710 OMIM
G Arnt aryl hydrocarbon receptor nuclear translocator GBrowse link ISS 2 190,333,978 190,391,015 RGD:734608 RGD
G Bmi1 Bmi1 polycomb ring finger oncogene GBrowse link ISS 17 92,784,216 92,787,947 RGD:1580059 RGD
G Cbfb core-binding factor, beta subunit GBrowse link ISS 19 34,985,879 35,029,446 RGD:7240710 OMIM
G Ccna1 cyclin A1 GBrowse link ISS 2 144,275,211 144,285,196 RGD:2316304 RGD
G Cd86 CD86 molecule GBrowse link ISS 11 66,215,233 66,238,882 RGD:4892295 RGD
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha GBrowse link ISS 1 87,626,111 87,627,499 RGD:7240710 OMIM
G Chi3l1 chitinase 3-like 1 (cartilage glycoprotein-39) GBrowse link Severity ISS 13 47,139,658 47,147,591 RGD:4892644 RGD
G Chic2 cysteine-rich hydrophobic domain 2 GBrowse link ISS 14 35,522,470 35,558,067 RGD:7240710 OMIM
G Crebbp CREB binding protein GBrowse link ISS 10 11,598,680 11,724,122 RGD:734819 RGD
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 GBrowse link Susceptibility ISS 1 81,345,425 81,359,415 RGD:6480472 RGD
G Etv6 ets variant 6 GBrowse link ISS 4 170,909,412 171,150,381 RGD:7240710 OMIM
G Flt3 fms-related tyrosine kinase 3 GBrowse link ISS 12 8,193,629 8,268,682 RGD:1598955 RGD
G Flt3 fms-related tyrosine kinase 3 GBrowse link ISS 12 8,193,629 8,268,682 RGD:7240710 OMIM
G Gata2 GATA binding protein 2 GBrowse link ISS 4 122,279,753 122,288,528 RGD:7240710 OMIM
G Gmps guanine monphosphate synthetase GBrowse link ISS 2 153,804,512 153,840,009 RGD:7240710 OMIM
G Jak2 Janus kinase 2 GBrowse link ISS 1 232,915,995 232,974,763 RGD:7240710 OMIM
G Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link ISS 14 34,906,043 34,984,819 RGD:7240710 OMIM
G Kmt2a lysine (K)-specific methyltransferase 2A GBrowse link ISS 8 47,759,175 47,834,586 RGD:1625285 RGD
G Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog GBrowse link ISS 4 182,869,242 182,895,106 RGD:1600469 RGD
G Lpp LIM domain containing preferred translocation partner in lipoma GBrowse link ISS 11 77,963,582 78,416,872 RGD:7240710 OMIM
G Mlf1 myeloid leukemia factor 1 GBrowse link ISS 2 157,230,783 157,263,847 RGD:1600902 RGD
G Mlf1 myeloid leukemia factor 1 GBrowse link ISS 2 157,230,783 157,263,847 RGD:7240710 OMIM
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link ISS 10 18,051,990 18,062,714 RGD:1600907 RGD
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link ISS 10 18,051,990 18,062,714 RGD:1600902 RGD
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link ISS 10 18,051,990 18,062,714 RGD:7240710 OMIM
G Nsd1 nuclear receptor binding SET domain protein 1 GBrowse link ISS 17 15,362,482 15,471,961 RGD:7240710 OMIM
G Nup214 nucleoporin 214 GBrowse link ISS 3 11,079,165 11,165,173 RGD:7240710 OMIM
G Nup98 nucleoporin 98 GBrowse link ISS 1 159,598,048 159,696,720 RGD:737758 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link Susceptibility ISS 1 146,754,085 146,834,197 RGD:1600760 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link ISS 1 146,754,085 146,834,197 RGD:7240710 OMIM
G Runx1 runt-related transcription factor 1 GBrowse link Disease_progression ISS 11 32,623,461 32,725,404 RGD:6482833 RGD
G Runx1 runt-related transcription factor 1 GBrowse link ISS 11 32,623,461 32,725,404 RGD:7240710 OMIM
G Tert telomerase reverse transcriptase GBrowse link ISS 1 30,445,180 30,465,942 RGD:7240710 OMIM
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 ISS RGD:2317350 RGD
G Whsc1l1 Wolf-Hirschhorn syndrome candidate 1-like 1 GBrowse link ISS 16 70,733,902 70,839,802 RGD:7240710 OMIM
G Zfp91 zinc finger protein 91 GBrowse link IED 1 215,846,158 215,882,704 RGD:727221 RGD
Leukemia, Megakaryoblastic, Acute term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Gata1 GATA binding protein 1 GBrowse link ISS X 26,564,259 26,572,081 RGD:704404 RGD
G Mkl1 megakaryoblastic leukemia (translocation) 1 GBrowse link ISS 7 119,306,220 119,415,012 RGD:1599948 RGD
G Sncb synuclein, beta GBrowse link ISS 17 15,907,498 15,915,705 RGD:6478703 RGD
Leukemia, Monocytic, Acute term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Mllt10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 GBrowse link ISS 17 92,246,466 92,389,861 RGD:1598771 RGD
Leukemia, Promyelocytic, Acute term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ccl7 chemokine (C-C motif) ligand 7 GBrowse link IEP 10 70,267,281 70,269,131 RGD:5130982 RGD
G Notch1 notch 1 GBrowse link ISS 3 4,631,797 4,677,640 RGD:1580761 RGD
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link ISS 10 18,051,990 18,062,714 RGD:1600902 RGD
G Rara retinoic acid receptor, alpha GBrowse link ISS 10 87,740,479 87,753,265 RGD:1600902 RGD
G Rara retinoic acid receptor, alpha GBrowse link ISS 10 87,740,479 87,753,265 RGD:7240710 OMIM
G Zbtb16 zinc finger and BTB domain containing 16 GBrowse link ISS 8 51,931,530 52,094,813 RGD:1599922 RGD
Platelet Disorder, Familial, with Associated Myeloid Malignancy term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Runx1 runt-related transcription factor 1 GBrowse link ISS 11 32,623,461 32,725,404 RGD:7240710 OMIM
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  Diseases 30477
    Neoplasms 5210
      Neoplasms by Histologic Type 1784
        Leukemia 126
          Leukemia, Myeloid 74
            Leukemia, Myeloid, Acute 48
              Dohle Bodies and Leukemia 0
              Erythroleukemia, Familial 0
              Leukemia, Acute Myelocytic, with Polyposis Coli and Colon Cancer 0
              Leukemia, Basophilic, Acute 0
              Leukemia, Eosinophilic, Acute 0
              Leukemia, Erythroblastic, Acute + 0
              Leukemia, Mast-Cell 0
              Leukemia, Megakaryoblastic, Acute + 3
              Leukemia, Monocytic, Acute 1
              Leukemia, Promyelocytic, Acute 6
              Monosomy 7 of Bone Marrow 0
              Platelet Disorder, Familial, with Associated Myeloid Malignancy 1
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