ONTOLOGY REPORT - ANNOTATIONS
Term: Germinoma
Accession: RDO:0005406
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Definition: A malignant neoplasm of the germinal tissue of the GONADS; MEDIASTINUM; or pineal region. Germinomas are uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular eosinophilic-staining cytoplasm. (Stedman, 265th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1642-3)
Synonyms: exact_synonym: Germinomas
primary_id: MESH:D018237
Germinoma
G
Braf
v-raf murine sarcoma viral oncogene homolog B1
ISS
4
67,117,759
67,243,058
RGD:2315865
RGD
G
Ccnd2
cyclin D2
ISS
4
163,523,817
163,546,501
RGD:2296039
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISS
5
108,908,749
108,916,380
RGD:2289698
RGD
G
Cdkn2a_v1
cyclin-dependent kinase inhibitor 2A, variant 1
ISS
RGD:2289698
RGD
G
Cdkn2a_v2
cyclin-dependent kinase inhibitor 2A, variant 2
ISS
RGD:2289698
RGD
G
Mgp
matrix Gla protein
ISS
4
173,910,595
173,913,917
RGD:2293578
RGD
G
Pdpn
podoplanin
ISS
5
162,142,251
162,175,921
RGD:2292236
RGD
Dysgerminoma
G
Amhr2
anti-Mullerian hormone receptor, type II
ISS
7
141,203,832
141,212,653
RGD:2315651
RGD
G
Fgfr2
fibroblast growth factor receptor 2
ISS
1
189,482,975
189,589,279
RGD:2289660
RGD
G
Inha
inhibin alpha
ISS
9
74,781,223
74,784,124
RGD:2290380
RGD
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
ISS
14
34,906,043
34,984,819
RGD:2292181
RGD
G
Pou5f1
POU class 5 homeobox 1
ISS
RGD:2292443
RGD
G
St14
suppression of tumorigenicity 14 (colon carcinoma)
ISS
8
30,916,769
30,932,214
RGD:2315091
RGD
Seminoma
G
Ccnd2
cyclin D2
ISS
4
163,523,817
163,546,501
RGD:2289154
RGD
G
Chek2
checkpoint kinase 2
ISS
12
45,933,900
45,965,427
RGD:2298484
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
ISS
1
238,259,443
238,274,745
RGD:2290049
RGD
G
Faslg
Fas ligand (TNF superfamily, member 6)
ISS
13
77,472,950
77,480,210
RGD:2290049
RGD
G
Fhit
fragile histidine triad
ISS
15
15,823,461
17,329,184
RGD:2289879
RGD
G
Hmbs
hydroxymethylbilane synthase
ISS
8
47,314,235
47,321,604
RGD:2301683
RGD
G
Hras
Harvey rat sarcoma virus oncogene
ISS
1
201,385,705
201,388,987
RGD:2314832
RGD
G
Inha
inhibin alpha
ISS
9
74,781,223
74,784,124
RGD:2290380
RGD
G
Insr
insulin receptor
ISS
12
2,934,967
3,087,691
RGD:2290460
RGD
G
Jup
junction plakoglobin
ISS
10
89,307,938
89,335,254
RGD:2291872
RGD
G
Kcne1
potassium voltage-gated channel, Isk-related family, member 1
ISS
11
32,344,529
32,355,189
RGD:1580497
RGD
G
Kcnq1
potassium voltage-gated channel, KQT-like subfamily, member 1
ISS
1
203,383,401
203,803,687
RGD:1580497
RGD
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
ISS
14
34,906,043
34,984,819
RGD:2292181
RGD
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ISS
4
182,869,242
182,895,106
RGD:2314915
RGD
G
Pcna
proliferating cell nuclear antigen
Disease_progression
ISS
3
120,008,715
120,012,589
RGD:2315012
RGD
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
ISS
14
35,369,422
35,418,126
RGD:2292154
RGD
G
Pdpn
podoplanin
ISS
5
162,142,251
162,175,921
RGD:2292234
RGD
G
Pla2g16
phospholipase A2, group XVI
ISS
1
210,281,109
210,315,280
RGD:2290002
RGD
G
Pou5f1
POU class 5 homeobox 1
ISS
RGD:2292429
RGD
G
Pou5f1
POU class 5 homeobox 1
ISS
RGD:2292432
RGD
G
Pou5f1
POU class 5 homeobox 1
ISS
RGD:2292433
RGD
G
Prmt5
protein arginine methyltransferase 5
ISS
15
32,574,951
32,584,336
RGD:2299953
RGD
G
Rb1
retinoblastoma 1
ISS
15
53,828,881
53,962,099
RGD:2299891
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:2299975
RGD
G
Tspy1
testis specific protein, Y-linked 1
ISS
RGD:2315445
RGD
G
Tymp
thymidine phosphorylase
ISS
7
127,666,518
127,671,624
RGD:2293724
RGD
G
Vegfa
vascular endothelial growth factor A
Disease_progression
ISS
9
10,520,730
10,536,071
RGD:2315467
RGD
G
Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
Susceptibility
ISS
1
79,834,167
79,860,300
RGD:2302576
RGD
G
Zfp354a
zinc finger protein 354A
ISS
10
36,654,406
36,665,659
RGD:2291889
RGD
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