ONTOLOGY REPORT - ANNOTATIONS
Term: Substance-Related Disorders
Accession: RDO:0005102
browse the term
Definition: Disorders related to substance abuse, the side effects of a medication, or toxin exposure.
Synonyms: exact_synonym: Drug Abuse; Drug Addiction; Drug Dependence; Drug Habituation; Drug Usage; Drug Use Disorder; Drug Use Disorders; Organic Mental Disorders, Substance Induced; Substance Abuse; Substance Abuses; Substance Addiction; Substance Dependence; Substance Use Disorder; Substance Use Disorders
primary_id: MESH:D019966
alt_id: OMIM:602935
Substance-Related Disorders
G
Disc1
disrupted in schizophrenia 1
Severity
ISS
19
55,265,116
55,449,375
RGD:5509834
RGD
G
Faah
fatty acid amide hydrolase
ISS
5
136,310,965
136,329,817
RGD:1625741
RGD
G
Faah
fatty acid amide hydrolase
ISS
5
136,310,965
136,329,817
RGD:1300311
RGD
G
Faah
fatty acid amide hydrolase
ISS
5
136,310,965
136,329,817
RGD:7240710
OMIM
G
Faslg
Fas ligand (TNF superfamily, member 6)
IED
13
77,472,950
77,480,210
RGD:1358616
RGD
G
Htr2c
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IPM
X
31,012,921
31,244,127
RGD:2292548
RGD
G
Pten
phosphatase and tensin homolog
IPM
1
236,771,027
236,837,261
RGD:2292548
RGD
G
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
IEP
1
265,789,917
265,824,551
RGD:5131179
RGD
ALCOHOL SENSITIVITY, ACUTE
G
Aldh2
aldehyde dehydrogenase 2 family (mitochondrial)
ISS
12
36,081,778
36,116,445
RGD:7240710
OMIM
Alcohol Withdrawal Delirium
G
Cnr1
cannabinoid receptor 1 (brain)
ISS
5
50,427,173
50,445,471
RGD:1626329
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISS
13
64,427,288
64,432,978
RGD:5688289
RGD
Alcohol-Induced Disorders
Q
Alcrsp1
Alcohol response QTL 1
Susceptibility
IED
1
102,248,992
147,248,992
RGD:1334439
RGD
Q
Alcrsp10
Alcohol response QTL 10
Susceptibility
IED
11
9,165,656
54,165,656
RGD:1334439
RGD
Q
Alcrsp11
Alcohol response QTL 11
Susceptibility
IED
14
76,579,917
112,194,335
RGD:1334439
RGD
Q
Alcrsp12
Alcohol response QTL 12
Susceptibility
IED
9
24,535,785
69,535,785
RGD:1334439
RGD
Q
Alcrsp13
Alcohol response QTL 13
Susceptibility
IED
9
1
39,963,583
RGD:1334439
RGD
Q
Alcrsp14
Alcohol response QTL 14
Susceptibility
IED
15
1
44,953,103
RGD:1334439
RGD
Q
Alcrsp15
Alcohol response QTL 16
Susceptibility
IED
RGD:1334439
RGD
Q
Alcrsp16
Alcohol response QTL 16
Susceptibility
IED
RGD:1334439
RGD
Q
Alcrsp17
Alcohol response QTL 17
Susceptibility
IED
2
155,101,972
247,295,816
RGD:1334439
RGD
Q
Alcrsp18
Alcohol response QTL 18
Susceptibility
IED
5
36,386,126
148,460,381
RGD:1334439
RGD
Q
Alcrsp19
Alcohol response QTL 19
IAGP
1
102,248,992
147,248,992
RGD:2317807
RGD
Q
Alcrsp2
Alcohol response QTL 2
Susceptibility
IED
2
155,101,972
230,157,845
RGD:1334439
RGD
Q
Alcrsp20
Alcohol response QTL 20
IAGP
RGD:2317807
RGD
Q
Alcrsp21
Alcohol response QTL 21
IAGP
19
4,997,213
49,997,213
RGD:2317807
RGD
Q
Alcrsp22
Alcohol response QTL 22
IAGP
20
1
27,477,794
RGD:2317807
RGD
Q
Alcrsp23
Alcohol response QTL 23
IAGP
RGD:2317807
RGD
Q
Alcrsp24
Alcohol response QTL 24
IAGP
8
1
25,539,735
RGD:2317807
RGD
Q
Alcrsp25
Alcohol response QTL 25
IAGP
20
18,303,073
55,268,282
RGD:2317807
RGD
Q
Alcrsp26
Alcohol response QTL 26
IAGP
3
147,516,452
171,063,335
RGD:2317807
RGD
Q
Alcrsp27
Alcohol response QTL 27
IAGP
14
62,384,564
107,384,564
RGD:2317807
RGD
Q
Alcrsp28
Alcohol response QTL 28
IAGP
2
222,136,025
258,207,540
RGD:2317807
RGD
Q
Alcrsp3
Alcohol response QTL 3
Susceptibility
IED
5
13,886,258
58,886,258
RGD:1334439
RGD
Q
Alcrsp4
Alcohol response QTL 4
Susceptibility
IED
6
70,874,239
115,874,239
RGD:1334439
RGD
Q
Alcrsp5
Alcohol response QTL 5
Susceptibility
IED
12
13,948,769
46,782,294
RGD:1334439
RGD
Q
Alcrsp6
Alcohol response QTL 6
Susceptibility
IED
13
55,689,252
100,689,252
RGD:1334439
RGD
Q
Alcrsp7
Alcohol response QTL 7
Susceptibility
IED
20
1
27,477,794
RGD:1334439
RGD
Q
Alcrsp8
Alcohol response QTL 8
Susceptibility
IED
5
36,386,126
71,377,566
RGD:1334439
RGD
Q
Alcrsp9
Alcohol response QTL 9
Susceptibility
IED
7
27,664,404
72,664,404
RGD:1334439
RGD
S
AT.ANT-(D1Rat158-D1Rat228 )/Rar
IAGP
1
43,820,945
153,578,547
RGD:2317807
RGD
S
AT.ANT-(D1Rat183-D1Rat228 )/Rar
IAGP
1
43,820,945
131,123,541
RGD:2317807
RGD
S
AT.ANT-(D1Rat234-D1Rat158 )/Rar
IAGP
1
41,225,047
153,578,547
RGD:2317807
RGD
S
AT.ANT-(D1Rat234-D1Rat228 )/Rar
IAGP
1
41,225,047
43,821,344
RGD:2317807
RGD
S
AT.ANT-(D1Rat234-D1Rat35 )/Rar
IAGP
1
41,225,047
124,749,065
RGD:2317807
RGD
S
AT.ANT-(D1Rat234-D1Rat38 )/Rar
IAGP
1
41,225,047
133,567,105
RGD:2317807
RGD
S
AT.ANT-(D1Rat234-D1Rat47 )/Rar
IAGP
1
41,225,047
158,511,230
RGD:2317807
RGD
S
AT.ANT-(D1Rat273-D1Rat158 )/Rar
IAGP
1
140,644,473
153,578,547
RGD:2317807
RGD
S
AT.ANT-(D1Rat273-D1Rat228 )/Rar
IAGP
1
43,820,945
140,644,634
RGD:2317807
RGD
S
AT.ANT-(D1Rat35-D1Rat228 )/Rar
IAGP
1
43,820,945
124,749,065
RGD:2317807
RGD
S
AT.ANT-(D1Rat35-D1Rat38 )/Rar
IAGP
1
124,748,920
133,567,105
RGD:2317807
RGD
S
AT.ANT-(D1Rat35-D1Rat47 )/Rar
IAGP
1
124,748,920
158,511,230
RGD:2317807
RGD
S
HAS.LAS-(D2Rat38-D2Rat69 )
IAGP
2
155,101,972
247,295,816
RGD:1600610
RGD
S
HAS.LAS-(D5Rat70-D5Rat37 )
IAGP
5
36,386,126
148,460,381
RGD:1600610
RGD
Alcohol-Induced Disorders, Nervous System
G
Aif1
allograft inflammatory factor 1
IEP
20
3,714,428
3,716,327
RGD:2313030
RGD
Alcoholism
G
Adh1
alcohol dehydrogenase 1 (class I)
ISS
2
235,799,396
235,811,584
RGD:7240710
OMIM
G
Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
IPM
2
235,979,108
235,991,515
RGD:5129091
RGD
G
Aldh2
aldehyde dehydrogenase 2 family (mitochondrial)
ISS
12
36,081,778
36,116,445
RGD:734551
RGD
G
Crh
corticotropin releasing hormone
IEP
2
104,764,023
104,765,887
RGD:5508173
RGD
G
Crhr1
corticotropin releasing hormone receptor 1
ISS
10
93,312,405
93,354,229
RGD:734822
RGD
G
Dbh
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
ISS
3
6,052,706
6,069,826
RGD:1625571
RGD
G
Dbh
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
No_Association
ISS
3
6,052,706
6,069,826
RGD:1625572
RGD
G
Drd2
dopamine receptor D2
IEA
8
52,641,160
52,707,749
RGD:1331525
RGD
G
Gabra2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
ISS
14
39,568,677
39,705,897
RGD:7240710
OMIM
G
Gabra2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
Susceptibility
ISS
14
39,568,677
39,705,897
RGD:6480257
RGD
G
Grin1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
ISS
3
3,453,784
3,480,381
RGD:1642372
RGD
G
Grin2b
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
ISS
4
172,721,895
173,183,187
RGD:1642372
RGD
G
Grin2b
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
ISS
4
172,721,895
173,183,187
RGD:1642200
RGD
G
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ISS
15
55,463,743
55,532,293
RGD:7240710
OMIM
G
Htr3b
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
Susceptibility
ISS
8
52,198,432
52,228,238
RGD:6480660
RGD
G
Htr7
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
ISS
1
240,136,279
240,260,620
RGD:6482181
RGD
G
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
ISS
11
35,025,118
35,116,500
RGD:6483053
RGD
G
Maoa
monoamine oxidase A
Susceptibility
ISS
X
17,678,960
17,745,908
RGD:1600720
RGD
G
Npy
neuropeptide Y
IAGP
4
78,038,013
78,045,187
RGD:1357412
RGD
G
Rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
ISS
15
38,291,075
38,371,308
RGD:7240710
OMIM
G
Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Susceptibility
ISS
10
67,134,790
67,155,891
RGD:6480660
RGD
G
Tas2r118
taste receptor, type 2, member 118
ISS
4
50,342,537
50,343,436
RGD:7240710
OMIM
G
Tph1
tryptophan hydroxylase 1
ISS
1
97,186,071
97,207,551
RGD:1580464
RGD
Q
Alc10
Alcohol consumption QTL 10
IED
12
20,932,559
41,447,890
RGD:731212
RGD
Q
Alc11
Alcohol consumption QTL 11
IED
16
4,304,396
64,081,533
RGD:731212
RGD
Q
Alc12
Alcohol consumption QTL 12
IED
10
17,515,123
19,815,204
RGD:731212
RGD
Q
Alc13
Alcohol consumption QTL 13
IED
16
4,304,396
16,536,977
RGD:731212
RGD
Q
Alc14
Alcohol consumption QTL 14
IED
4
58,421,110
158,108,528
RGD:731213
RGD
Q
Alc15
Alcohol consumption QTL 15
IED
2
192,489,056
237,489,056
RGD:731213
RGD
Q
Alc16
Alcohol consumption QTL 16
IED
4
58,421,110
158,108,528
RGD:731213
RGD
Q
Alc17
Alcohol consumption QTL 17
IED
6
1
35,786,687
RGD:731213
RGD
Q
Alc18
Alcohol consumption QTL 18
IED
4
54,828,166
152,570,244
RGD:69704
RGD
Q
Alc19
Alcohol consumption QTL 19
IED
3
1
23,762,628
RGD:69704
RGD
Q
Alc20
Alcohol consumption QTL 20
IED
8
32,203,394
43,314,410
RGD:69704
RGD
Q
Alc21
Alcohol consumption QTL 21
IAGP
4
54,879,077
127,941,994
RGD:1578304
RGD
Q
Alc21
Alcohol consumption QTL 21
IED
4
54,879,077
127,941,994
RGD:61483
RGD
Q
Alc22
Alcohol consumption QTL 22
IAGP
4
62,832,008
127,941,994
RGD:1578304
RGD
Q
Alc23
Alcohol consumption QTL 23
IAGP
RGD:6218999
RGD
Q
Alc4
Alcohol consumption QTL 4
IED
5
10,517,466
18,944,220
RGD:631230
RGD
Q
Alc5
Alcohol consumption QTL 5
IED
10
5,090,008
17,515,458
RGD:724636
RGD
Q
Alc6
Alcohol consumption QTL 6
IED
12
29,675,888
39,018,219
RGD:631230
RGD
Q
Alc7
Alcohol consumption QTL 7
IED
16
1
26,804,456
RGD:724636
RGD
Q
Alc8
Alcohol consumption QTL 8
IED
3
1
29,749,474
RGD:631229
RGD
Q
Alc9
Alcohol consumption QTL 9
IED
10
5,090,008
19,648,894
RGD:731212
RGD
Q
Sach1
Saccharin preference QTL 1
IAGP
3
23,762,471
41,420,436
RGD:631229
RGD
Q
Sach4
Saccharine consumption QTL 4
IAGP
4
58,421,110
158,108,528
RGD:731213
RGD
Q
Sach5
Saccharine consumption QTL 5
IAGP
6
1
43,326,782
RGD:731213
RGD
S
FH/Unc
Fawn-hooded
Model
IED
RGD:1643000
RGD
S
HAD1
high-alcohol-drinking
Susceptibility
IED
RGD:731212
RGD
S
HAD2
high-alcohol-drinking
Susceptibility
IED
RGD:731212
RGD
S
HAS1
High Alcohol Sensitive strain 1
IED
RGD:1334439
RGD
S
HEP
high ethanol preferring
IED
RGD:731213
RGD
S
LAD1
low-alcohol-drinking
Resistance
IED
RGD:731212
RGD
S
LAD2
low-alcohol-drinking
Resistance
IED
RGD:731212
RGD
S
LAS1
Low Alcohol Sensitive strain 1
IED
RGD:1334439
RGD
S
LEW/NIcoCrlf
Resistance
TAS
RGD:1598390
RGD
S
MR/Pit
TAS
RGD:1004
RGD
S
NP/Iusm
alcohol-nonpreferring
Not
IED
RGD:631849
RGD
S
P
alcohol-preferring
Model
IED
RGD:69704
RGD
S
P
alcohol-preferring
Model
TAS
RGD:69704
RGD
S
P.NP-(D4Rat119-D4Rat55 )/Iusm
Not
IAGP
4
62,832,008
127,941,994
RGD:1578304
RGD
S
P/Iusm
alcohol-preferring
Model
IED
RGD:631849
RGD
S
SHR/NIcoCrlf
TAS
RGD:1598390
RGD
S
WHP
Warsaw High Prefering
IED
RGD:1358540
RGD
S
WLP
Warsaw Low Prefering
IED
RGD:1358540
RGD
Arsenic Poisoning
G
Alad
aminolevulinate dehydratase
IEP
5
79,505,645
79,515,983
RGD:4144202
RGD
Cadmium Poisoning
G
Mt2A
metallothionein 2A
IEP
19
11,267,811
11,268,585
RGD:6483854
RGD
G
Mt3
metallothionein 3
ISS
19
11,284,554
11,286,402
RGD:6480620
RGD
G
Mt3
metallothionein 3
ISS
19
11,284,554
11,286,402
RGD:6480494
RGD
Carbon Monoxide Poisoning
G
Hmox1
heme oxygenase (decycling) 1
IEP
19
13,963,139
13,969,960
RGD:4145288
RGD
G
Hmox1
heme oxygenase (decycling) 1
IED
19
13,963,139
13,969,960
RGD:4145306
RGD
Carbon Tetrachloride Poisoning
G
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
IEP
1
157,925,514
157,928,222
RGD:7204431
RGD
Cardiomyopathy, Alcoholic
G
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
IEA
10
95,361,338
95,381,455
RGD:1331525
RGD
G
Nos1
nitric oxide synthase 1, neuronal
IEP
12
39,812,500
39,869,484
RGD:1642138
RGD
G
Pparg
peroxisome proliferator-activated receptor gamma
IEP
4
151,492,220
151,617,331
RGD:2301868
RGD
G
Rxra
retinoid X receptor alpha
IEP
3
6,605,782
6,689,224
RGD:2317465
RGD
Cocaine-Related Disorders
G
Aanat
aralkylamine N-acetyltransferase
ISS
10
106,709,371
106,713,683
RGD:704409
RGD
G
Cdk5
cyclin-dependent kinase 5
ISS
4
6,119,704
6,124,186
RGD:734739
RGD
G
Crh
corticotropin releasing hormone
IEP
2
104,764,023
104,765,887
RGD:5508177
RGD
G
Crhr1
corticotropin releasing hormone receptor 1
IEP
10
93,312,405
93,354,229
RGD:5508175
RGD
G
Drd2
dopamine receptor D2
IED
8
52,641,160
52,707,749
RGD:2311586
RGD
G
Htr3b
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
Susceptibility
ISS
8
52,198,432
52,228,238
RGD:6480660
RGD
G
Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Susceptibility
ISS
10
67,134,790
67,155,891
RGD:6480660
RGD
G
Snca
synuclein, alpha (non A4 component of amyloid precursor)
ISS
4
89,613,731
89,722,807
RGD:6480198
RGD
G
Sncg
synuclein, gamma (breast cancer-specific protein 1)
IPM
16
10,025,978
10,030,516
RGD:6218958
RGD
Drug Toxicity
G
Ass1
argininosuccinate synthase 1
IEP
3
10,578,717
10,622,332
RGD:4140449
RGD
Q
Mcs25
Mammary carcinoma susceptibility QTL 25
IED
6
7,161,389
115,238,799
RGD:4143380
RGD
Drug-Induced Liver Injury
G
Ada
adenosine deaminase
IEP
3
154,636,530
154,660,637
RGD:5128859
RGD
G
Ak4
adenylate kinase 4
IEP
5
122,062,872
122,119,335
RGD:2301096
RGD
G
Aldh2
aldehyde dehydrogenase 2 family (mitochondrial)
IEP
12
36,081,778
36,116,445
RGD:7241599
RGD
G
Cast
calpastatin
IEP
2
1,495,048
1,608,477
RGD:5683869
RGD
G
Cpb2
carboxypeptidase B2 (plasma)
IEP
15
56,104,920
56,154,321
RGD:7243112
RGD
G
F2
coagulation factor II
IED
3
76,005,318
76,018,603
RGD:6893482
RGD
G
Il1b
interleukin 1 beta
IED
3
116,964,422
116,970,867
RGD:7204421
RGD
G
Keap1
Kelch-like ECH-associated protein 1
ISS
8
20,259,178
20,266,351
RGD:6893370
RGD
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
ISS
3
58,366,693
58,394,116
RGD:6893370
RGD
G
Ppara
peroxisome proliferator activated receptor alpha
ISS
7
123,729,774
123,807,090
RGD:5509941
RGD
G
RT1-CE7
RT1 class I, locus CE7
ISS
20
3,410,094
3,413,041
RGD:7240710
OMIM
G
Serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
IEP
6
127,998,617
128,021,719
RGD:1643168
RGD
Drug-Induced Liver Injury, Chronic
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
IED
2
27,127,504
27,149,580
RGD:2316848
RGD
Dyskinesia, Drug-Induced
G
Abat
4-aminobutyrate aminotransferase
IPM
10
7,040,725
7,137,154
RGD:1598524
RGD
G
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
IPM
16
5,383,259
5,703,361
RGD:6906919
RGD
G
Comt
catechol-O-methyltransferase
IPM
11
84,561,591
84,581,713
RGD:2289781
RGD
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
ISS
8
61,439,062
61,447,861
RGD:1358545
RGD
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
ISS
7
120,742,273
120,752,274
RGD:1358547
RGD
G
Ddc
dopa decarboxylase (aromatic L-amino acid decarboxylase)
IEP
14
92,698,636
92,788,635
RGD:5128860
RGD
G
Drd2
dopamine receptor D2
IED
8
52,641,160
52,707,749
RGD:2311579
RGD
G
Grk6
G protein-coupled receptor kinase 6
IPM
17
15,220,992
15,236,617
RGD:5684919
RGD
G
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IPM
2
36,434,518
36,435,786
RGD:5683628
RGD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
IEP
1
208,262,669
208,273,148
RGD:2298778
RGD
Epidermal Necrolysis, Toxic
G
RT1-CE7
RT1 class I, locus CE7
ISS
20
3,410,094
3,413,041
RGD:7240710
OMIM
Fatty Liver, Alcoholic
G
Adipoq
adiponectin, C1Q and collagen domain containing
ISS
11
79,908,291
79,911,065
RGD:5686674
RGD
G
Aldh2
aldehyde dehydrogenase 2 family (mitochondrial)
IED
12
36,081,778
36,116,445
RGD:1599041
RGD
G
Ctsb
cathepsin B
IEP
15
42,402,829
42,423,701
RGD:2315516
RGD
G
Pemt
phosphatidylethanolamine N-methyltransferase
IEP
RGD:1642369
RGD
G
Serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
IEP
10
62,713,441
62,739,444
RGD:2312349
RGD
G
Sod2
superoxide dismutase 2, mitochondrial
IEP
1
41,862,997
41,870,327
RGD:1625694
RGD
G
Stat4
signal transducer and activator of transcription 4
IEP
9
46,510,251
46,650,076
RGD:7207884
RGD
Fetal Alcohol Syndrome
G
Rhoa
ras homolog family member A
IEP
RGD:2298867
RGD
Heavy Metal Poisoning, Nervous System
G
Il16
interleukin 16
IEP
1
139,908,061
140,000,146
RGD:1354526
RGD
Hepatitis, Alcoholic
G
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ISS
19
54,738,556
54,750,349
RGD:1601135
RGD
G
Col1a1
collagen, type I, alpha 1
ISS
10
83,622,438
83,639,368
RGD:5688335
RGD
G
Il13
interleukin 13
IEP
10
39,093,512
39,096,069
RGD:1581860
RGD
Heroin Dependence
G
Chrm2
cholinergic receptor, muscarinic 2
ISS
4
63,911,292
63,913,354
RGD:5509583
RGD
G
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
ISS
11
35,025,118
35,116,500
RGD:6483055
RGD
Lathyrism
G
Kdr
kinase insert domain receptor
IEP
RGD:5684396
RGD
Lead Poisoning
G
Alad
aminolevulinate dehydratase
Induced
IED
5
79,505,645
79,515,983
RGD:1599014
RGD
G
Alad
aminolevulinate dehydratase
IEP
5
79,505,645
79,515,983
RGD:4144142
RGD
G
Qdpr
quinoid dihydropteridine reductase
IEP
14
70,741,998
70,755,600
RGD:5128598
RGD
Lead Poisoning, Nervous System, Adult
G
Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
IEP
4
150,249,867
150,265,186
RGD:1643208
RGD
Liver Cirrhosis, Alcoholic
G
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
ISS
10
89,519,421
89,525,978
RGD:6483345
RGD
G
Crp
C-reactive protein, pentraxin-related
Severity
ISS
13
88,702,243
88,703,153
RGD:6482305
RGD
G
Fabp2
fatty acid binding protein 2, intestinal
ISS
2
219,591,502
219,605,097
RGD:1578455
RGD
G
Plau
plasminogen activator, urokinase
IED
15
3,680,072
3,686,232
RGD:7241800
RGD
G
Tlr9
toll-like receptor 9
ISS
RGD:5130706
RGD
Liver Diseases, Alcoholic
G
C6
complement component 6
Resistance
IAGP
2
53,691,290
53,764,539
RGD:1600673
RGD
G
Cd27
CD27 molecule
IEP
4
161,351,797
161,356,688
RGD:1581860
RGD
G
Cd59
CD59 molecule, complement regulatory protein
IEP
3
89,243,600
89,245,129
RGD:1600486
RGD
G
Cxcl1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
IEP
14
18,690,339
18,692,118
RGD:5135271
RGD
G
Cxcl2
chemokine (C-X-C motif) ligand 2
IEP
14
18,677,129
18,679,175
RGD:5135271
RGD
G
Cxcl5
chemokine (C-X-C motif) ligand 5
IEP
14
18,825,357
18,826,269
RGD:5135271
RGD
G
Igf2
insulin-like growth factor 2
IEP
1
202,906,624
202,915,231
RGD:5510002
RGD
G
Il1b
interleukin 1 beta
IEP
3
116,964,422
116,970,867
RGD:7204488
RGD
G
Keap1
Kelch-like ECH-associated protein 1
ISS
8
20,259,178
20,266,351
RGD:6892954
RGD
G
Mif
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
IEP
20
13,191,986
13,192,851
RGD:1642007
RGD
G
Mmp9
matrix metallopeptidase 9
IEP
3
155,985,473
155,993,433
RGD:1642042
RGD
G
Nedd8
neural precursor cell expressed, developmentally down-regulated 8
ISS
15
33,797,457
33,820,624
RGD:1549458
RGD
G
Otc
ornithine carbamoyltransferase
IEP
X
24,609,141
24,685,341
RGD:4144059
RGD
G
Plaur
plasminogen activator, urokinase receptor
ISS
1
79,708,646
79,712,881
RGD:6484116
RGD
G
Ppara
peroxisome proliferator activated receptor alpha
Severity
ISS
7
123,729,774
123,807,090
RGD:5683636
RGD
Manganese Poisoning
G
Alad
aminolevulinate dehydratase
IEP
5
79,505,645
79,515,983
RGD:4144152
RGD
Mercury Poisoning
G
Gpx1
glutathione peroxidase 1
ISS
RGD:7240571
RGD
G
Icam1
intercellular adhesion molecule 1
IEP
8
20,040,177
20,051,939
RGD:4145621
RGD
Mercury Poisoning, Nervous System
G
Ctsb
cathepsin B
IPM
15
42,402,829
42,423,701
RGD:2315510
RGD
Morphine Dependence
G
Drd2
dopamine receptor D2
IEP
8
52,641,160
52,707,749
RGD:2311587
RGD
Neurotoxicity Syndromes
G
Drd2
dopamine receptor D2
IEP
8
52,641,160
52,707,749
RGD:2311553
RGD
G
Epha4
Eph receptor A4
IEP
9
76,676,778
76,820,752
RGD:5688752
RGD
G
Ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
Susceptibility
ISS
13
96,722,973
96,752,940
RGD:5490249
RGD
G
Gstm1
glutathione S-transferase mu 1
Susceptibility
ISS
2
203,575,444
203,580,821
RGD:5490214
RGD
G
Gstp1
glutathione S-transferase pi 1
Susceptibility
ISS
1
206,627,398
206,629,866
RGD:5490249
RGD
G
Igf1r
insulin-like growth factor 1 receptor
ISS
1
122,704,976
122,990,007
RGD:5686413
RGD
G
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
IEP
1
265,789,917
265,824,551
RGD:5130970
RGD
Pancreatitis, Alcoholic
G
Ugt1a7c
UDP glucuronosyltransferase 1 family, polypeptide A7C
ISS
9
87,029,500
87,098,362
RGD:2317503
RGD
Poisoning
G
Ache
acetylcholinesterase
IED
RGD:5688054
RGD
G
Pon1
paraoxonase 1
ISS
4
29,936,314
29,964,821
RGD:7240710
OMIM
SEVERE CUTANEOUS ADVERSE REACTION, SUSCEPTIBILITY TO
G
RT1-CE7
RT1 class I, locus CE7
ISS
20
3,410,094
3,413,041
RGD:7240710
OMIM
Substance Abuse, Intravenous
G
Cnr1
cannabinoid receptor 1 (brain)
ISS
5
50,427,173
50,445,471
RGD:1358448
RGD
Substance Withdrawal Syndrome
G
Aldh2
aldehyde dehydrogenase 2 family (mitochondrial)
ISS
12
36,081,778
36,116,445
RGD:7240710
OMIM
G
Crh
corticotropin releasing hormone
IEP
2
104,764,023
104,765,887
RGD:5508177
RGD
G
Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
IEP
4
150,249,867
150,265,186
RGD:1643202
RGD
G
Th
tyrosine hydroxylase
IEP
1
203,164,253
203,171,506
RGD:5128830
RGD
TOBACCO ADDICTION, SUSCEPTIBILITY TO
G
Chrna4
cholinergic receptor, nicotinic, alpha 4 (neuronal)
ISS
3
170,171,214
170,185,998
RGD:7240710
OMIM
G
Gabbr2
gamma-aminobutyric acid (GABA) B receptor 2
ISS
5
63,241,397
63,611,907
RGD:7240710
OMIM
G
Slc6a3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
ISS
1
30,516,568
30,557,540
RGD:7240710
OMIM
Tobacco Use Disorder
G
Chrna7
cholinergic receptor, nicotinic, alpha 7 (neuronal)
IED
1
117,587,580
117,716,267
RGD:704388
RGD
G
Egfr
epidermal growth factor receptor
IEP
14
97,617,358
97,788,211
RGD:5131452
RGD
G
Tlr3
toll-like receptor 3
ISS
16
50,112,910
50,126,371
RGD:5129228
RGD
G
Tph1
tryptophan hydroxylase 1
ISS
1
97,186,071
97,207,551
RGD:1580461
RGD
Wernicke Encephalopathy
G
Ptgs2
prostaglandin-endoperoxide synthase 2
IPM
13
64,427,288
64,432,978
RGD:2300278
RGD
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