ONTOLOGY REPORT - ANNOTATIONS

Term:Alcoholism
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Accession:RDO:0004798 term browser browse the term
Definition:A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Synonyms:exact_synonym: ALCOHOL DEPENDENCE;   Alcohol Abuse;   Chronic Alcoholic Intoxication
 primary_id: MESH:D000437
 alt_id: OMIM:103780;   OMIM:604867

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Alcoholism term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Adh1 alcohol dehydrogenase 1 (class I) GBrowse link ISS 2 235,799,396 235,811,584 RGD:7240710 OMIM
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide GBrowse link IPM 2 235,979,108 235,991,515 RGD:5129091 RGD
G Aldh2 aldehyde dehydrogenase 2 family (mitochondrial) GBrowse link ISS 12 36,081,778 36,116,445 RGD:734551 RGD
G Crh corticotropin releasing hormone GBrowse link IEP 2 104,764,023 104,765,887 RGD:5508173 RGD
G Crhr1 corticotropin releasing hormone receptor 1 GBrowse link ISS 10 93,312,405 93,354,229 RGD:734822 RGD
G Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) GBrowse link ISS 3 6,052,706 6,069,826 RGD:1625571 RGD
G Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) GBrowse link No_Association ISS 3 6,052,706 6,069,826 RGD:1625572 RGD
G Drd2 dopamine receptor D2 GBrowse link IEA 8 52,641,160 52,707,749 RGD:1331525 RGD
G Gabra2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 GBrowse link ISS 14 39,568,677 39,705,897 RGD:7240710 OMIM
G Gabra2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 GBrowse link Susceptibility ISS 14 39,568,677 39,705,897 RGD:6480257 RGD
G Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 GBrowse link ISS 3 3,453,784 3,480,381 RGD:1642372 RGD
G Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B GBrowse link ISS 4 172,721,895 173,183,187 RGD:1642372 RGD
G Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B GBrowse link ISS 4 172,721,895 173,183,187 RGD:1642200 RGD
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled GBrowse link ISS 15 55,463,743 55,532,293 RGD:7240710 OMIM
G Htr3b 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic GBrowse link Susceptibility ISS 8 52,198,432 52,228,238 RGD:6480660 RGD
G Htr7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled GBrowse link ISS 1 240,136,279 240,260,620 RGD:6482181 RGD
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 GBrowse link ISS 11 35,025,118 35,116,500 RGD:6483053 RGD
G Maoa monoamine oxidase A GBrowse link Susceptibility ISS X 17,678,960 17,745,908 RGD:1600720 RGD
G Npy neuropeptide Y GBrowse link IAGP 4 78,038,013 78,045,187 RGD:1357412 RGD
G Rcbtb1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 GBrowse link ISS 15 38,291,075 38,371,308 RGD:7240710 OMIM
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 GBrowse link Susceptibility ISS 10 67,134,790 67,155,891 RGD:6480660 RGD
G Tas2r118 taste receptor, type 2, member 118 GBrowse link ISS 4 50,342,537 50,343,436 RGD:7240710 OMIM
G Tph1 tryptophan hydroxylase 1 GBrowse link ISS 1 97,186,071 97,207,551 RGD:1580464 RGD
Q Alc10 Alcohol consumption QTL 10 GBrowse link IED 12 20,932,559 41,447,890 RGD:731212 RGD
Q Alc11 Alcohol consumption QTL 11 GBrowse link IED 16 4,304,396 64,081,533 RGD:731212 RGD
Q Alc12 Alcohol consumption QTL 12 GBrowse link IED 10 17,515,123 19,815,204 RGD:731212 RGD
Q Alc13 Alcohol consumption QTL 13 GBrowse link IED 16 4,304,396 16,536,977 RGD:731212 RGD
Q Alc14 Alcohol consumption QTL 14 GBrowse link IED 4 58,421,110 158,108,528 RGD:731213 RGD
Q Alc15 Alcohol consumption QTL 15 GBrowse link IED 2 192,489,056 237,489,056 RGD:731213 RGD
Q Alc16 Alcohol consumption QTL 16 GBrowse link IED 4 58,421,110 158,108,528 RGD:731213 RGD
Q Alc17 Alcohol consumption QTL 17 GBrowse link IED 6 1 35,786,687 RGD:731213 RGD
Q Alc18 Alcohol consumption QTL 18 GBrowse link IED 4 54,828,166 152,570,244 RGD:69704 RGD
Q Alc19 Alcohol consumption QTL 19 GBrowse link IED 3 1 23,762,628 RGD:69704 RGD
Q Alc20 Alcohol consumption QTL 20 GBrowse link IED 8 32,203,394 43,314,410 RGD:69704 RGD
Q Alc21 Alcohol consumption QTL 21 GBrowse link IAGP 4 54,879,077 127,941,994 RGD:1578304 RGD
Q Alc21 Alcohol consumption QTL 21 GBrowse link IED 4 54,879,077 127,941,994 RGD:61483 RGD
Q Alc22 Alcohol consumption QTL 22 GBrowse link IAGP 4 62,832,008 127,941,994 RGD:1578304 RGD
Q Alc23 Alcohol consumption QTL 23 IAGP RGD:6218999 RGD
Q Alc4 Alcohol consumption QTL 4 GBrowse link IED 5 10,517,466 18,944,220 RGD:631230 RGD
Q Alc5 Alcohol consumption QTL 5 GBrowse link IED 10 5,090,008 17,515,458 RGD:724636 RGD
Q Alc6 Alcohol consumption QTL 6 GBrowse link IED 12 29,675,888 39,018,219 RGD:631230 RGD
Q Alc7 Alcohol consumption QTL 7 GBrowse link IED 16 1 26,804,456 RGD:724636 RGD
Q Alc8 Alcohol consumption QTL 8 GBrowse link IED 3 1 29,749,474 RGD:631229 RGD
Q Alc9 Alcohol consumption QTL 9 GBrowse link IED 10 5,090,008 19,648,894 RGD:731212 RGD
Q Sach1 Saccharin preference QTL 1 GBrowse link IAGP 3 23,762,471 41,420,436 RGD:631229 RGD
Q Sach4 Saccharine consumption QTL 4 GBrowse link IAGP 4 58,421,110 158,108,528 RGD:731213 RGD
Q Sach5 Saccharine consumption QTL 5 GBrowse link IAGP 6 1 43,326,782 RGD:731213 RGD
S FH/Unc Fawn-hooded Model IED RGD:1643000 RGD
S HAD1 high-alcohol-drinking Susceptibility IED RGD:731212 RGD
S HAD2 high-alcohol-drinking Susceptibility IED RGD:731212 RGD
S HAS1 High Alcohol Sensitive strain 1 IED RGD:1334439 RGD
S HEP high ethanol preferring IED RGD:731213 RGD
S LAD1 low-alcohol-drinking Resistance IED RGD:731212 RGD
S LAD2 low-alcohol-drinking Resistance IED RGD:731212 RGD
S LAS1 Low Alcohol Sensitive strain 1 IED RGD:1334439 RGD
S LEW/NIcoCrlf Resistance TAS RGD:1598390 RGD
S MR/Pit TAS RGD:1004 RGD
S NP/Iusm alcohol-nonpreferring Not IED RGD:631849 RGD
S P alcohol-preferring Model IED RGD:69704 RGD
S P alcohol-preferring Model TAS RGD:69704 RGD
S P.NP-(D4Rat119-D4Rat55)/Iusm GBrowse link Not IAGP 4 62,832,008 127,941,994 RGD:1578304 RGD
S P/Iusm alcohol-preferring Model IED RGD:631849 RGD
S SHR/NIcoCrlf TAS RGD:1598390 RGD
S WHP Warsaw High Prefering IED RGD:1358540 RGD
S WLP Warsaw Low Prefering IED RGD:1358540 RGD
Term paths to the root
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  Diseases 30477
    Substance-Related Disorders 233
      Alcohol-Related Disorders 148
        Alcoholism 65
Path 2
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  Diseases 30477
    Mental Disorders 1629
      Substance-Related Disorders 233
        Alcohol-Related Disorders 148
          Alcoholism 65
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