ONTOLOGY REPORT - ANNOTATIONS
Term: Gastrointestinal Neoplasms
Accession: RDO:0001736
browse the term
Definition: Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
Synonyms: exact_synonym: Cancer of Gastrointestinal Tract; Cancer of the Gastrointestinal Tract; Gastrointestinal Cancer; Gastrointestinal Cancers; Gastrointestinal Neoplasm; Gastrointestinal Tract Cancer; Gastrointestinal Tract Cancers
primary_id: MESH:D005770
Gastrointestinal Neoplasms
G
Cd44
Cd44 molecule
ISS
3
88,022,962
88,110,352
RGD:2289345
RGD
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
ISS
14
34,906,043
34,984,819
RGD:1600047
RGD
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:2290476
RGD
G
Pten
phosphatase and tensin homolog
ISS
1
236,771,027
236,837,261
RGD:2290476
RGD
Adenocarcinoma Of Esophagus
G
Mmp1
matrix metallopeptidase 1 (interstitial collagenase)
Susceptibility
ISS
8
4,333,773
4,354,284
RGD:7207058
RGD
G
Mmp12
matrix metallopeptidase 12
ISS
8
4,249,938
4,259,675
RGD:7207058
RGD
G
Mmp3
matrix metallopeptidase 3
ISS
8
4,315,601
4,329,146
RGD:7207058
RGD
Adenomatous Polyposis Coli
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:2293188
RGD
G
Apc
adenomatous polyposis coli
IEA
18
26,732,147
26,790,383
RGD:1331525
RGD
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:7240710
OMIM
G
ApcPirc
adenomatous polyposis coli
IED
RGD:1601201
RGD
G
Bmpr1a
bone morphogenetic protein receptor, type IA
ISS
16
10,061,943
10,105,854
RGD:734650
RGD
G
Mutyh
mutY homolog (E. coli)
ISS
5
137,103,958
137,115,897
RGD:1600191
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:1599899
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:1599898
RGD
S
F344-ApcPirc Uwm
IED
RGD:1601201
RGD
Carcinoid Tumors, Intestinal
G
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
ISS
8
53,955,067
53,964,547
RGD:7240710
OMIM
Carney-Stratakis Syndrome
G
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
ISS
5
159,818,669
159,839,772
RGD:7240710
OMIM
G
Sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
ISS
13
87,014,569
87,035,239
RGD:7240710
OMIM
G
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
ISS
8
53,955,067
53,964,547
RGD:7240710
OMIM
Colonic Neoplasms
G
Acvr2a
activin A receptor, type IIA
ISS
3
29,779,827
29,808,881
RGD:2301065
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
Onset
IEP
1
82,686,233
82,726,544
RGD:2313394
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
Onset
ISS
1
82,686,233
82,726,544
RGD:2313394
RGD
G
Anxa7
annexin A7
ISS
15
4,047,956
4,075,981
RGD:2292654
RGD
G
Apc
adenomatous polyposis coli
IPM
18
26,732,147
26,790,383
RGD:1601201
RGD
G
Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
IEP
4
159,033,170
159,048,108
RGD:625559
RGD
G
Bard1
BRCA1 associated RING domain 1
IED
9
70,120,151
70,198,591
RGD:632230
RGD
G
Bcl2
B-cell CLL/lymphoma 2
IEP
13
12,730,736
12,905,108
RGD:2293078
RGD
G
Brca1
breast cancer 1, early onset
Susceptibility
ISS
10
90,513,630
90,572,676
RGD:1599497
RGD
G
Ccl2
chemokine (C-C motif) ligand 2
IEP
10
70,256,263
70,258,061
RGD:5135051
RGD
G
Ccl3
chemokine (C-C motif) ligand 3
IEP
10
71,744,559
71,746,109
RGD:5135051
RGD
G
Ccnd2
cyclin D2
IEP
4
163,523,817
163,546,501
RGD:2289181
RGD
G
Ccne1
cyclin E1
IEP
1
90,568,189
90,577,426
RGD:2289293
RGD
G
Cd40lg
CD40 ligand
ISS
X
141,925,019
141,937,183
RGD:5490978
RGD
G
Cd59
CD59 molecule, complement regulatory protein
IPM
3
89,243,600
89,245,129
RGD:1600485
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
IEP
5
108,908,749
108,916,380
RGD:1600823
RGD
G
Col18a1
collagen, type XVIII, alpha 1
Severity
IED
20
11,920,816
11,982,468
RGD:1600901
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
IAGP
8
125,978,161
125,987,670
RGD:1599637
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
Resistance
IEP
1
238,259,443
238,274,745
RGD:1600355
RGD
G
Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
ISS
16
37,419,901
37,457,896
RGD:5688759
RGD
G
Hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
ISS
1
180,202,791
180,324,718
RGD:2317633
RGD
G
Kdr
kinase insert domain receptor
ISS
RGD:5684533
RGD
G
Klf5
Kruppel-like factor 5
Model
ISS
15
83,103,177
83,118,363
RGD:1304288
RGD
G
Mgmt
O-6-methylguanine-DNA methyltransferase
IEP
1
196,629,366
196,866,937
RGD:1599637
RGD
G
Mki67
antigen identified by monoclonal antibody Ki-67
ISS
1
195,310,027
195,336,224
RGD:6483523
RGD
G
Mmp9
matrix metallopeptidase 9
Disease_progression
IEP
3
155,985,473
155,993,433
RGD:2325778
RGD
G
Mmp9
matrix metallopeptidase 9
IED
3
155,985,473
155,993,433
RGD:5135051
RGD
G
Mre11a
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
ISS
8
11,588,409
11,632,483
RGD:2317740
RGD
G
Mtus1
microtubule associated tumor suppressor 1
ISS
16
54,611,502
54,664,075
RGD:2317016
RGD
G
Myc
myelocytomatosis oncogene
Treatment
IED
7
98,953,142
98,958,060
RGD:7240527
RGD
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISS
19
19,662,337
19,697,341
RGD:5131515
RGD
G
Nqo1
NAD(P)H dehydrogenase, quinone 1
IED
19
37,251,147
37,266,040
RGD:5133247
RGD
G
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
ISS
18
57,014,475
57,053,581
RGD:2292176
RGD
G
Pecam1
platelet/endothelial cell adhesion molecule 1
ISS
10
96,056,220
96,057,232
RGD:6771355
RGD
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:5685670
RGD
G
Pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
ISS
2
32,602,673
32,675,350
RGD:2290476
RGD
G
Plau
plasminogen activator, urokinase
Treatment
ISS
15
3,680,072
3,686,232
RGD:7241805
RGD
G
Plau
plasminogen activator, urokinase
ISS
15
3,680,072
3,686,232
RGD:7241262
RGD
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
ISS
12
11,004,507
11,028,754
RGD:1599141
RGD
G
Pparg
peroxisome proliferator-activated receptor gamma
ISS
4
151,492,220
151,617,331
RGD:1601444
RGD
G
Prf1
perforin 1 (pore forming protein)
IED
20
28,658,367
28,663,877
RGD:6482822
RGD
G
Prf1
perforin 1 (pore forming protein)
ISS
20
28,658,367
28,663,877
RGD:6482812
RGD
G
Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
ISS
2
54,327,821
54,360,462
RGD:5685669
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
IPM
13
64,427,288
64,432,978
RGD:5135051
RGD
G
Runx3
runt-related transcription factor 3
ISS
5
153,950,116
153,973,141
RGD:2302551
RGD
G
Src
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Disease_progression
ISS
3
148,157,256
148,170,524
RGD:1601371
RGD
G
Tgfbr2
transforming growth factor, beta receptor II
ISS
8
120,593,595
120,680,453
RGD:2301065
RGD
G
Tnfrsf17
tumor necrosis factor receptor superfamily, member 17
ISS
10
4,187,672
4,193,420
RGD:2317311
RGD
G
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
IEP
4
162,172,563
162,185,252
RGD:5131434
RGD
G
Tnfrsf1b
tumor necrosis factor receptor superfamily, member 1b
ISS
5
163,666,541
163,697,484
RGD:5131434
RGD
G
Vegfa
vascular endothelial growth factor A
ISS
9
10,520,730
10,536,071
RGD:5684533
RGD
G
Vegfa
vascular endothelial growth factor A
IEP
9
10,520,730
10,536,071
RGD:5135051
RGD
G
Vegfc
vascular endothelial growth factor C
IEP
16
40,624,435
40,739,692
RGD:2315488
RGD
S
BDII
TAS
RGD:1004
RGD
S
F344-ApcPirc Uwm
IED
RGD:1601201
RGD
S
WF
Wistar Furth
TAS
RGD:1004
RGD
Colorectal Adenomatous Polyposis, Autosomal Recessive
G
Mutyh
mutY homolog (E. coli)
ISS
5
137,103,958
137,115,897
RGD:7240710
OMIM
Colorectal Cancer, Hereditary Nonpolyposis, Type 8
G
Epcam
epithelial cell adhesion molecule
ISS
6
11,176,664
11,192,628
RGD:7240710
OMIM
Colorectal Neoplasms
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Susceptibility
ISS
4
21,709,855
21,796,628
RGD:2312343
RGD
G
Abcb1b
ATP-binding cassette, subfamily B (MDR/TAP), member 1B
IED
4
21,829,489
21,912,239
RGD:1598563
RGD
G
Acads
acyl-CoA dehydrogenase, C-2 to C-3 short chain
ISS
12
42,765,284
42,774,528
RGD:1300335
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
ISS
6
137,640,482
137,657,552
RGD:2313763
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
Susceptibility
ISS
6
137,640,482
137,657,552
RGD:1643334
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
ISS
6
137,640,482
137,657,552
RGD:7240710
OMIM
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:2293188
RGD
G
Apc
adenomatous polyposis coli
IEA
18
26,732,147
26,790,383
RGD:1331525
RGD
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:7240710
OMIM
G
ApcPirc
adenomatous polyposis coli
IED
RGD:1601201
RGD
G
Atp12a
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ISS
15
35,295,274
35,321,453
RGD:704409
RGD
G
Aurka
aurora kinase A
ISS
3
163,270,479
163,284,506
RGD:7240710
OMIM
G
Axin1
axin 1
ISS
10
15,409,373
15,462,726
RGD:2293188
RGD
G
Axin2
axin 2
ISS
10
98,294,466
98,321,830
RGD:704404
RGD
G
Axin2
axin 2
ISS
10
98,294,466
98,321,830
RGD:2293188
RGD
G
Axin2
axin 2
ISS
10
98,294,466
98,321,830
RGD:7240710
OMIM
G
Bax
Bcl2-associated X protein
Susceptibility
ISS
1
95,933,023
95,938,176
RGD:734633
RGD
G
Bcl10
B-cell CLL/lymphoma 10
ISS
2
244,116,880
244,126,393
RGD:7240710
OMIM
G
Bmi1
Bmi1 polycomb ring finger oncogene
ISS
17
92,784,216
92,787,947
RGD:1580058
RGD
G
Braf
v-raf murine sarcoma viral oncogene homolog B1
ISS
4
67,117,759
67,243,058
RGD:2298531
RGD
G
Bub1
BUB1 mitotic checkpoint serine/threonine kinase
Susceptibility
ISS
3
115,323,510
115,354,906
RGD:1600539
RGD
G
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
ISS
3
105,063,018
105,116,145
RGD:7240710
OMIM
G
Calu
calumenin
ISS
4
56,228,617
56,256,118
RGD:2316232
RGD
G
Ccnd1
cyclin D1
TAS
1
205,357,235
205,366,757
RGD:704404
RGD
G
Ccnd1
cyclin D1
ISS
1
205,357,235
205,366,757
RGD:7240710
OMIM
G
Cd44
Cd44 molecule
Disease_progression
ISS
3
88,022,962
88,110,352
RGD:2289356
RGD
G
Chek2
checkpoint kinase 2
Susceptibility
ISS
12
45,933,900
45,965,427
RGD:2289706
RGD
G
Chek2
checkpoint kinase 2
ISS
12
45,933,900
45,965,427
RGD:7240710
OMIM
G
Chi3l1
chitinase 3-like 1 (cartilage glycoprotein-39)
Severity
ISS
13
47,139,658
47,147,591
RGD:4892637
RGD
G
Crp
C-reactive protein, pentraxin-related
IEP
13
88,702,243
88,703,153
RGD:6903278
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
Disease_progression
IEP
8
125,978,161
125,987,670
RGD:2289840
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
ISS
8
125,978,161
125,987,670
RGD:2293188
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
ISS
8
125,978,161
125,987,670
RGD:7240710
OMIM
G
Ctps2
CTP synthase 2
Resistance
ISS
X
52,387,522
52,541,409
RGD:5132879
RGD
G
Cxcl5
chemokine (C-X-C motif) ligand 5
Disease_progression
IPM
14
18,825,357
18,826,269
RGD:5135268
RGD
G
Dcc
deleted in colorectal carcinoma
ISS
18
68,026,795
69,140,741
RGD:734878
RGD
G
Dcc
deleted in colorectal carcinoma
ISS
18
68,026,795
69,140,741
RGD:7240710
OMIM
G
Dlc1
deleted in liver cancer 1
ISS
16
59,312,930
59,355,129
RGD:1300391
RGD
G
Egfr
epidermal growth factor receptor
ISS
14
97,617,358
97,788,211
RGD:5131455
RGD
G
Egfr
epidermal growth factor receptor
ISS
14
97,617,358
97,788,211
RGD:5131632
RGD
G
Egfr
epidermal growth factor receptor
Resistance
ISS
14
97,617,358
97,788,211
RGD:5131871
RGD
G
Ep300
E1A binding protein p300
ISS
7
119,938,507
120,008,886
RGD:7240710
OMIM
G
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Susceptibility
ISS
9
66,843,898
67,967,970
RGD:2289977
RGD
G
Fgfr3
fibroblast growth factor receptor 3
ISS
14
82,683,191
82,697,229
RGD:7240710
OMIM
G
Flcn
folliculin
ISS
10
46,110,527
46,129,613
RGD:7240710
OMIM
G
Galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
ISS
5
63,708,980
63,737,770
RGD:7240710
OMIM
G
Hspa8
heat shock 70kDa protein 8
Disease_progression
ISS
8
43,784,035
43,787,760
RGD:6480104
RGD
G
Itgb3
integrin, beta 3
Severity
ISS
RGD:5112894
RGD
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
TAS
4
182,869,242
182,895,106
RGD:2306732
RGD
G
L1cam
L1 cell adhesion molecule
Severity
ISS
X
159,784,792
159,801,553
RGD:6483011
RGD
G
Mbd4
methyl-CpG binding domain protein 4
Susceptibility
ISS
4
151,972,272
151,981,633
RGD:2316846
RGD
G
Met
met proto-oncogene
ISS
4
43,134,183
43,211,355
RGD:2317534
RGD
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:1625107
RGD
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:2306714
RGD
G
Mlh3
mutL homolog 3 (E. coli)
ISS
6
109,280,910
109,318,893
RGD:1600415
RGD
G
Mlh3
mutL homolog 3 (E. coli)
ISS
6
109,280,910
109,318,893
RGD:7240710
OMIM
G
Mmp1
matrix metallopeptidase 1 (interstitial collagenase)
Severity
ISS
8
4,333,773
4,354,284
RGD:7207022
RGD
G
Mmp3
matrix metallopeptidase 3
Susceptibility
ISS
8
4,315,601
4,329,146
RGD:7207065
RGD
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:2306714
RGD
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:2293519
RGD
G
Msh3
mutS homolog 3 (E. coli)
ISS
2
22,462,934
22,606,874
RGD:1625103
RGD
G
Nras
neuroblastoma ras oncogene
ISS
2
198,292,650
198,300,286
RGD:7240710
OMIM
G
Odc1
ornithine decarboxylase 1
ISS
6
41,309,211
41,315,796
RGD:7240710
OMIM
G
Pdgfrl
platelet-derived growth factor receptor-like
ISS
16
54,664,213
54,742,494
RGD:7240710
OMIM
G
Pecam1
platelet/endothelial cell adhesion molecule 1
ISS
10
96,056,220
96,057,232
RGD:6771214
RGD
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:7240710
OMIM
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
ISS
6
50,441,892
50,476,931
RGD:6482694
RGD
G
Pla2g2a
phospholipase A2, group IIA (platelets, synovial fluid)
ISS
5
157,654,786
157,657,360
RGD:619597
RGD
G
Pla2g2a
phospholipase A2, group IIA (platelets, synovial fluid)
ISS
5
157,654,786
157,657,360
RGD:7240710
OMIM
G
Pms1
postmeiotic segregation increased 1 (S. cerevisiae)
ISS
9
45,203,344
45,292,624
RGD:2306714
RGD
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
ISS
12
11,004,507
11,028,754
RGD:2306714
RGD
G
Psmb9
proteasome (prosome, macropain) subunit, beta type, 9
ISS
20
4,801,187
4,806,608
RGD:6483362
RGD
G
Ptprj
protein tyrosine phosphatase, receptor type, J
ISS
3
74,796,764
74,935,540
RGD:7240710
OMIM
G
Rhoa
ras homolog family member A
ISS
RGD:1547860
RGD
G
Runx3
runt-related transcription factor 3
ISS
5
153,950,116
153,973,141
RGD:2302552
RGD
G
Smad2
SMAD family member 2
ISS
18
73,180,520
73,241,707
RGD:2308865
RGD
G
Smad2
SMAD family member 2
ISS
18
73,180,520
73,241,707
RGD:2306282
RGD
G
Smad3
SMAD family member 3
ISS
8
67,803,909
67,952,056
RGD:2306282
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:2308865
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:2306282
RGD
G
Smad7
SMAD family member 7
ISS
18
72,294,803
72,323,354
RGD:2308865
RGD
G
Smad7
SMAD family member 7
ISS
18
72,294,803
72,323,354
RGD:7240710
OMIM
G
Sod2
superoxide dismutase 2, mitochondrial
ISS
1
41,862,997
41,870,327
RGD:1581258
RGD
G
Spint1
serine peptidase inhibitor, Kunitz type 1
ISS
3
105,757,666
105,770,345
RGD:1581311
RGD
G
Strap
serine/threonine kinase receptor associated protein
ISS
4
174,863,502
174,877,750
RGD:1581429
RGD
G
Sult1a1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
Onset
ISS
1
185,829,205
185,832,725
RGD:1581449
RGD
G
Tgfb1
transforming growth factor, beta 1
ISS
1
80,894,705
80,911,020
RGD:2306282
RGD
G
Tgfbr1
transforming growth factor, beta receptor 1
ISS
5
63,976,868
64,034,058
RGD:2306282
RGD
G
Tgfbr2
transforming growth factor, beta receptor II
ISS
8
120,593,595
120,680,453
RGD:2308865
RGD
G
Tgfbr2
transforming growth factor, beta receptor II
ISS
8
120,593,595
120,680,453
RGD:2306282
RGD
G
Tlr2
toll-like receptor 2
ISS
2
175,607,990
175,613,992
RGD:7240710
OMIM
G
Tlr4
toll-like receptor 4
ISS
5
83,564,100
83,577,735
RGD:7240710
OMIM
G
Tnfsf9
tumor necrosis factor (ligand) superfamily, member 9
ISS
RGD:2317353
RGD
G
Tp53
tumor protein p53
IEA
10
56,399,721
56,411,150
RGD:1331525
RGD
G
Tp53
tumor protein p53
ISS
10
56,399,721
56,411,150
RGD:7240710
OMIM
G
Trpv3
transient receptor potential cation channel, subfamily V, member 3
ISS
10
60,126,243
60,171,718
RGD:7183081
RGD
G
Txnip
thioredoxin interacting protein
Disease_progression
IEP
2
191,356,954
191,360,757
RGD:1642760
RGD
G
Tyms
thymidylate synthetase
ISS
9
112,604,912
112,617,706
RGD:5133430
RGD
G
Tyms
thymidylate synthetase
IEP
9
112,604,912
112,617,706
RGD:5133433
RGD
G
Tyms
thymidylate synthetase
IEP
9
112,604,912
112,617,706
RGD:2317418
RGD
Q
Colcr1
Colorectal carcinoma resistance QTL 1
IAGP
4
1
26,178,440
RGD:1625309
RGD
Q
Colcr2
Colorectal carcinoma resistance QTL 2
IAGP
15
2,306,220
25,410,881
RGD:1625309
RGD
Q
Colcr3
Colorectal carcinoma resistance QTL 3
IAGP
18
2,571,631
22,807,391
RGD:1625309
RGD
Q
Colcr4
Colorectal carcinoma resistance QTL4
IAGP
6
33,021,033
64,955,579
RGD:1625309
RGD
Q
Colcr5
Colorectal carcinoma resistance QTL 5
IAGP
6
127,683,728
144,152,572
RGD:1625309
RGD
Q
Colcr6
Colorectal carcinoma resistance QTL 6
IAGP
15
80,361,961
107,849,649
RGD:1625309
RGD
Q
Colcr7
Colorectal carcinoma resistance QTL 7
IAGP
17
7,696,509
27,724,805
RGD:1625309
RGD
Q
Colcr8
Colorectal carcinoma resistance QTL 8
IAGP
18
22,807,203
54,605,912
RGD:1625309
RGD
Q
Colcr9
Colorectal carcinoma resistance QTL 9
IAGP
20
1
32,560,683
RGD:1625309
RGD
Q
Colcs1
Colorectal carcinoma susceptibility QTL 1
IAGP
RGD:1625309
RGD
S
F344-ApcPirc Uwm
IED
RGD:1601201
RGD
S
WF/CrCrli
IED
RGD:1625309
RGD
Colorectal Neoplasms, Hereditary Nonpolyposis
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:1625106
RGD
G
Mlh3
mutL homolog 3 (E. coli)
ISS
6
109,280,910
109,318,893
RGD:7240710
OMIM
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:1625106
RGD
G
Msh6
mutS homolog 6 (E. coli)
ISS
6
11,525,292
11,542,592
RGD:7240710
OMIM
G
Pms1
postmeiotic segregation increased 1 (S. cerevisiae)
ISS
9
45,203,344
45,292,624
RGD:1599137
RGD
G
Pms1
postmeiotic segregation increased 1 (S. cerevisiae)
ISS
9
45,203,344
45,292,624
RGD:7240710
OMIM
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
ISS
12
11,004,507
11,028,754
RGD:7240710
OMIM
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
ISS
12
11,004,507
11,028,754
RGD:1599142
RGD
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
ISS
12
11,004,507
11,028,754
RGD:1599137
RGD
G
Rnasel
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
Onset
ISS
13
68,822,013
68,829,264
RGD:2292000
RGD
G
Smad2
SMAD family member 2
ISS
18
73,180,520
73,241,707
RGD:1599900
RGD
G
Smad3
SMAD family member 3
ISS
8
67,803,909
67,952,056
RGD:1599900
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:1599900
RGD
G
Tgfbr2
transforming growth factor, beta receptor II
ISS
8
120,593,595
120,680,453
RGD:7240710
OMIM
Desmoid disease, hereditary
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:7240710
OMIM
Duodenal Neoplasms
G
Men1
multiple endocrine neoplasia I
ISS
1
209,114,987
209,120,837
RGD:2317341
RGD
Esophageal Neoplasms
G
Acadsb
acyl-CoA dehydrogenase, short/branched chain
ISS
1
190,987,657
191,026,275
RGD:1300336
RGD
G
Aldob
aldolase B, fructose-bisphosphate
IEP
5
66,283,165
66,296,171
RGD:1599639
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
IEP
5
108,908,749
108,916,380
RGD:1600828
RGD
G
Ctnna1
catenin (cadherin-associated protein), alpha 1, 102kDa
Disease_progression
IEP
18
27,629,915
27,769,360
RGD:2289811
RGD
G
Ctsb
cathepsin B
IED
15
42,402,829
42,423,701
RGD:734853
RGD
G
Ctsc
cathepsin C
IEP
1
144,629,802
144,661,183
RGD:1599639
RGD
G
Cxcl1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
IEP
14
18,690,339
18,692,118
RGD:5134997
RGD
G
Dcc
deleted in colorectal carcinoma
ISS
18
68,026,795
69,140,741
RGD:734879
RGD
G
Dlc1
deleted in liver cancer 1
ISS
16
59,312,930
59,355,129
RGD:7240710
OMIM
G
Egfr
epidermal growth factor receptor
Severity
ISS
14
97,617,358
97,788,211
RGD:5131486
RGD
G
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
ISS
8
38,078,328
38,123,983
RGD:704404
RGD
G
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
ISS
8
38,078,328
38,123,983
RGD:7240710
OMIM
G
Gstt1
glutathione S-transferase theta 1
Susceptibility
ISS
20
13,604,355
13,621,456
RGD:5490562
RGD
G
Hmox1
heme oxygenase (decycling) 1
IEP
19
13,963,139
13,969,960
RGD:4145286
RGD
G
Krt14
keratin 14
IEP
10
89,144,357
89,148,415
RGD:1600174
RGD
G
Krt14l
keratin 14-like
TAS
RGD:633113
RGD
G
Lzts1
leucine zipper, putative tumor suppressor 1
ISS
16
22,243,137
22,300,978
RGD:1600104
RGD
G
Lzts1
leucine zipper, putative tumor suppressor 1
ISS
16
22,243,137
22,300,978
RGD:7240710
OMIM
G
Mxi1
MAX interactor 1, dimerization protein
IAGP
1
259,219,584
259,259,979
RGD:1298988
RGD
G
Myc
myelocytomatosis oncogene
Treatment
IED
7
98,953,142
98,958,060
RGD:7207890
RGD
G
Psmb9
proteasome (prosome, macropain) subunit, beta type, 9
Disease_progression
ISS
20
4,801,187
4,806,608
RGD:6482249
RGD
G
Ptgs1
prostaglandin-endoperoxide synthase 1
IEP
3
15,343,832
15,365,412
RGD:5687745
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
Susceptibility
ISS
13
64,427,288
64,432,978
RGD:5135528
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
IEP
13
64,427,288
64,432,978
RGD:5687745
RGD
G
Rnf6
ring finger protein (C3H2C3 type) 6
ISS
12
9,193,659
9,203,700
RGD:7240710
OMIM
G
Sod2
superoxide dismutase 2, mitochondrial
IED
1
41,862,997
41,870,327
RGD:2317403
RGD
G
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
ISS
20
4,790,363
4,800,730
RGD:6482249
RGD
G
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
ISS
20
4,770,446
4,784,488
RGD:6482249
RGD
G
Tgfbr2
transforming growth factor, beta receptor II
ISS
8
120,593,595
120,680,453
RGD:7240710
OMIM
G
Wwox
WW domain-containing oxidoreductase
ISS
19
44,516,391
44,829,849
RGD:1599874
RGD
G
Wwox
WW domain-containing oxidoreductase
ISS
19
44,516,391
44,829,849
RGD:7240710
OMIM
Esophageal Squamous Cell Carcinoma
G
Bmp6
bone morphogenetic protein 6
ISS
17
32,380,199
32,689,295
RGD:7242413
RGD
Gastrointestinal Stromal Tumors
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
ISS
14
34,906,043
34,984,819
RGD:7240710
OMIM
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
ISS
14
35,369,422
35,418,126
RGD:7240710
OMIM
G
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
ISS
5
159,818,669
159,839,772
RGD:7240710
OMIM
G
Sdhc
succinate dehydrogenase complex, subunit C, integral membrane protein
ISS
13
87,014,569
87,035,239
RGD:7240710
OMIM
Intestinal Neoplasms
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:7242058
RGD
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:6484212
RGD
G
Cdh2
cadherin 2
ISS
18
8,048,920
8,267,974
RGD:734737
RGD
G
Fen1
flap structure-specific endonuclease 1
Disease_progression
ISS
1
212,688,118
212,692,486
RGD:737746
RGD
G
Pla2g2a
phospholipase A2, group IIA (platelets, synovial fluid)
ISS
5
157,654,786
157,657,360
RGD:6482727
RGD
S
ACI/N
A X C 9935, Irish
TAS
RGD:1004
RGD
Lynch syndrome I (site-specific colonic cancer)
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:7240710
OMIM
Lynch Syndrome II
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:7240710
OMIM
Muir-Torre Syndrome
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:7240710
OMIM
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:7240710
OMIM
Oligodontia-Colorectal Cancer Syndrome
G
Axin2
axin 2
ISS
10
98,294,466
98,321,830
RGD:7240710
OMIM
Polyposis Syndrome, Hereditary Mixed, 2
G
Bmpr1a
bone morphogenetic protein receptor, type IA
ISS
16
10,061,943
10,105,854
RGD:7240710
OMIM
Rectal Neoplasms
G
Mthfr
methylenetetrahydrofolate reductase (NAD(P)H)
Severity
ISS
5
165,112,850
165,126,885
RGD:6893664
RGD
G
Nras
neuroblastoma ras oncogene
ISS
2
198,292,650
198,300,286
RGD:7240710
OMIM
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:5685669
RGD
G
Pmepa1
prostate transmembrane protein, androgen induced 1
ISS
3
164,094,654
164,140,142
RGD:2315108
RGD
Stomach Neoplasms
G
Apc
adenomatous polyposis coli
ISS
18
26,732,147
26,790,383
RGD:7240710
OMIM
G
Birc5
baculoviral IAP repeat-containing 5
IEP
RGD:2293138
RGD
G
Capn9
calpain 9
ISS
19
54,759,009
54,796,390
RGD:734688
RGD
G
Cd44
Cd44 molecule
Disease_progression
ISS
3
88,022,962
88,110,352
RGD:2289356
RGD
G
Cdh1
cadherin 1
ISS
19
36,442,693
36,512,091
RGD:7240710
OMIM
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
IAGP
5
108,908,749
108,916,380
RGD:1600820
RGD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
ISS
10
87,219,157
87,242,919
RGD:7240710
OMIM
G
Fgfr2
fibroblast growth factor receptor 2
ISS
1
189,482,975
189,589,279
RGD:7240710
OMIM
G
Htra2
HtrA serine peptidase 2
ISS
4
117,262,206
117,265,368
RGD:5688748
RGD
G
Il1b
interleukin 1 beta
ISS
3
116,964,422
116,970,867
RGD:7240710
OMIM
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:7240710
OMIM
G
Irf1
interferon regulatory factor 1
ISS
10
39,220,600
39,227,602
RGD:1600013
RGD
G
Irf1
interferon regulatory factor 1
ISS
10
39,220,600
39,227,602
RGD:7240710
OMIM
G
Klf6
Kruppel-like factor 6
ISS
17
75,578,498
75,585,072
RGD:7240710
OMIM
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ISS
4
182,869,242
182,895,106
RGD:1600468
RGD
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ISS
4
182,869,242
182,895,106
RGD:7240710
OMIM
G
Letmd1
LETM1 domain containing 1
ISS
7
139,172,373
139,181,857
RGD:2314918
RGD
G
Mmp1
matrix metallopeptidase 1 (interstitial collagenase)
ISS
8
4,333,773
4,354,284
RGD:7206857
RGD
G
Mmp2
matrix metallopeptidase 2
IEP
19
15,246,036
15,275,061
RGD:2325777
RGD
G
Mmp9
matrix metallopeptidase 9
IEP
3
155,985,473
155,993,433
RGD:2325777
RGD
G
Mre11a
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
ISS
8
11,588,409
11,632,483
RGD:2317738
RGD
G
Mutyh
mutY homolog (E. coli)
ISS
5
137,103,958
137,115,897
RGD:1600201
RGD
G
Mutyh
mutY homolog (E. coli)
ISS
5
137,103,958
137,115,897
RGD:7240710
OMIM
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISS
19
19,662,337
19,697,341
RGD:5508759
RGD
G
Parp1
poly (ADP-ribose) polymerase 1
Susceptibility
ISS
13
96,309,670
96,341,486
RGD:5683907
RGD
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:7240710
OMIM
G
Pmepa1
prostate transmembrane protein, androgen induced 1
ISS
3
164,094,654
164,140,142
RGD:2315108
RGD
G
Sod2
superoxide dismutase 2, mitochondrial
ISS
1
41,862,997
41,870,327
RGD:1581255
RGD
G
Sparc
secreted protein, acidic, cysteine-rich (osteonectin)
IEP
10
40,809,730
40,831,481
RGD:2300058
RGD
G
Spint1
serine peptidase inhibitor, Kunitz type 1
ISS
3
105,757,666
105,770,345
RGD:1581312
RGD
G
Spp1
secreted phosphoprotein 1
ISS
RGD:1581341
RGD
G
Sptbn1
spectrin, beta, non-erythrocytic 1
ISS
14
111,076,741
111,246,286
RGD:1581318
RGD
G
Sult1a1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
ISS
1
185,829,205
185,832,725
RGD:1581452
RGD
G
Terf1
telomeric repeat binding factor (NIMA-interacting) 1
ISS
5
2,556,918
2,586,086
RGD:2317220
RGD
G
Txnip
thioredoxin interacting protein
IEP
2
191,356,954
191,360,757
RGD:1642760
RGD
G
Znrd1
zinc ribbon domain containing 1
ISS
20
1,687,673
1,691,591
RGD:1323843
RGD
Q
Gcr1
Gastric cancer resistance QTL 1
IED
4
144,600,129
150,048,167
RGD:69698
RGD
Q
Gcr2
Gastric cancer resistance QTL 2
IED
3
4,010,230
23,762,628
RGD:69698
RGD
Q
Gcr3
Gastric cancer resistance QTL 3
IED
16
18,121,291
70,196,694
RGD:69698
RGD
Q
Gcs1
Gastric cancer susceptibility QTL1
IED
15
83,349,477
108,387,242
RGD:69698
RGD
S
ACI.BUF-(D15Rat97-D15Rat29 )/Ncc
Induced
TAS
15
78,048,029
108,387,411
RGD:1302502
RGD
S
ACI/N
A X C 9935, Irish
TAS
RGD:1004
RGD
S
BUF.ACI-(D15Rat68-D15Rat29 )/Ncc
Induced
TAS
15
62,521,452
108,387,411
RGD:1302502
RGD
S
BUF.ACI-(D16Rat31-D16Arb1 )/Ncc
Induced
TAS
16
8,340,080
8,340,453
RGD:1302502
RGD
S
BUF.ACI-(D3Rat56-D3Rat83 )/Ncc
Induced
TAS
3
3,577,905
42,635,088
RGD:1302502
RGD
S
BUF.ACI-(D4Rat192-D4Rat66 )/Ncc
Induced
TAS
4
161,023,350
161,023,765
RGD:1302502
RGD
S
BUF.ACI-(D4Rat226-D4Rat109 )/Ncc
Induced
TAS
4
61,542,056
117,094,107
RGD:1302502
RGD
S
LEW
Lewis
TAS
RGD:1004
RGD
Turcot syndrome
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:7240710
OMIM
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:7240710
OMIM
G
Msh6
mutS homolog 6 (E. coli)
ISS
6
11,525,292
11,542,592
RGD:7240710
OMIM
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
ISS
12
11,004,507
11,028,754
RGD:7240710
OMIM
Zollinger-Ellison Syndrome
G
Alb
albumin
ISS
14
19,126,935
19,142,214
RGD:2325683
RGD
G
Egf
epidermal growth factor
ISS
2
227,103,900
227,195,062
RGD:2317668
RGD
G
Igf1r
insulin-like growth factor 1 receptor
ISS
1
122,704,976
122,990,007
RGD:7242847
RGD
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest