ONTOLOGY REPORT - ANNOTATIONS
Term: Acute Kidney Injury
Accession: RDO:0001702
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Definition: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Synonyms: exact_synonym: Acute Kidney Failure; Acute Kidney Failures; Acute Kidney Injuries; Acute Kidney Insufficiencies; Acute Kidney Insufficiency; Acute Renal Failure; Acute Renal Failures; Acute Renal Injuries; Acute Renal Injury; Acute Renal Insufficiencies; Acute Renal Insufficiency
primary_id: MESH:D058186
Acute Kidney Injury
G
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
IPM
10
95,361,338
95,381,455
RGD:6893484
RGD
G
Adrb2
adrenoceptor beta 2, surface
IEP
18
58,174,958
58,177,000
RGD:7175276
RGD
G
Adrb2
adrenoceptor beta 2, surface
IPM
18
58,174,958
58,177,000
RGD:7175283
RGD
G
Adrb2
adrenoceptor beta 2, surface
ISS
18
58,174,958
58,177,000
RGD:7175276
RGD
G
Adrb2
adrenoceptor beta 2, surface
Treatment
ISS
18
58,174,958
58,177,000
RGD:7175281
RGD
G
Alad
aminolevulinate dehydratase
IEP
5
79,505,645
79,515,983
RGD:4144146
RGD
G
Alox5
arachidonate 5-lipoxygenase
IPM
4
152,610,283
152,657,891
RGD:2317536
RGD
G
Ambp
alpha-1-microglobulin/bikunin precursor
ISS
5
80,119,742
80,129,962
RGD:6904218
RGD
G
Arg1
arginase, liver
IEP
1
20,998,894
21,011,275
RGD:631989
RGD
G
Arg2
arginase type II
IEP
6
101,901,653
101,928,282
RGD:631989
RGD
G
Avpr1a
arginine vasopressin receptor 1A
IPM
7
62,225,537
62,229,461
RGD:2300348
RGD
G
B2m
beta-2 microglobulin
IEP
3
108,927,919
108,932,718
RGD:6482685
RGD
G
Casp1
caspase 1
IPM
8
2,027,976
2,036,872
RGD:2293624
RGD
G
Ccl3
chemokine (C-C motif) ligand 3
ISS
10
71,744,559
71,746,109
RGD:6906908
RGD
G
Ccl5
chemokine (C-C motif) ligand 5
ISS
10
71,605,791
71,610,330
RGD:4889990
RGD
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
IEP
4
171,841,705
171,846,506
RGD:2293624
RGD
G
Crp
C-reactive protein, pentraxin-related
IEP
13
88,702,243
88,703,153
RGD:6903282
RGD
G
Crp
C-reactive protein, pentraxin-related
ISS
13
88,702,243
88,703,153
RGD:6906888
RGD
G
Cxcl1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
ISS
14
18,690,339
18,692,118
RGD:7175314
RGD
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
IED
RGD:2307326
RGD
G
Ddit3
DNA-damage inducible transcript 3
IEP
7
67,247,749
67,252,571
RGD:1599736
RGD
G
Edn1
endothelin 1
ISS
17
28,303,886
28,309,775
RGD:4144852
RGD
G
Egf
epidermal growth factor
ISS
2
227,103,900
227,195,062
RGD:6906908
RGD
G
Fn1
fibronectin 1
IEP
9
70,702,181
70,771,155
RGD:729934
RGD
G
Fn1
fibronectin 1
IEP
9
70,702,181
70,771,155
RGD:7205684
RGD
G
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
IEP
3
109,558,043
109,565,432
RGD:1599823
RGD
G
Ghrl
ghrelin/obestatin prepropeptide
ISS
4
149,622,566
149,628,111
RGD:7242430
RGD
G
Gstp1
glutathione S-transferase pi 1
ISS
1
206,627,398
206,629,866
RGD:6903954
RGD
G
Hadhb
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
ISS
6
26,139,397
26,173,428
RGD:1600788
RGD
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
ISS
2
27,127,504
27,149,580
RGD:5508471
RGD
G
Hspa8
heat shock 70kDa protein 8
IEP
8
43,784,035
43,787,760
RGD:7242786
RGD
G
Igf1r
insulin-like growth factor 1 receptor
IEP
1
122,704,976
122,990,007
RGD:7242908
RGD
G
Il18
interleukin 18
ISS
8
53,936,584
53,943,228
RGD:6893450
RGD
G
Il1a
interleukin 1 alpha
ISS
3
116,913,612
116,924,114
RGD:6907069
RGD
G
Il1b
interleukin 1 beta
IEP
3
116,964,422
116,970,867
RGD:7175102
RGD
G
Il1b
interleukin 1 beta
ISS
3
116,964,422
116,970,867
RGD:7175258
RGD
G
Il1b
interleukin 1 beta
ISS
3
116,964,422
116,970,867
RGD:7175314
RGD
G
Il1b
interleukin 1 beta
IED
3
116,964,422
116,970,867
RGD:7175094
RGD
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:6907375
RGD
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:6907360
RGD
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:6907369
RGD
G
Il6
interleukin 6
ISS
4
456,799
461,376
RGD:5128661
RGD
G
Met
met proto-oncogene
IEP
4
43,134,183
43,211,355
RGD:2317469
RGD
G
Mpo
myeloperoxidase
ISS
10
76,085,872
76,097,012
RGD:6909168
RGD
G
Mpo
myeloperoxidase
IED
10
76,085,872
76,097,012
RGD:6909185
RGD
G
Myc
myelocytomatosis oncogene
Susceptibility
ISS
7
98,953,142
98,958,060
RGD:7207407
RGD
G
Parp1
poly (ADP-ribose) polymerase 1
ISS
13
96,309,670
96,341,486
RGD:5510015
RGD
G
Pkd2
polycystic kidney disease 2 (autosomal dominant)
IEP
14
6,349,519
6,392,988
RGD:7175293
RGD
G
Ppargc1a
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
ISS
14
64,278,115
64,370,912
RGD:7242026
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
IPM
13
64,427,288
64,432,978
RGD:5508181
RGD
G
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
IEP
1
211,758,103
211,761,651
RGD:2313129
RGD
G
Slc22a1
solute carrier family 22 (organic cation transporter), member 1
Treatment
IED
1
42,351,239
42,378,295
RGD:7243179
RGD
G
Slc22a2
solute carrier family 22 (organic cation transporter), member 2
Treatment
IED
1
42,395,676
42,442,847
RGD:7243179
RGD
G
Slc34a1
solute carrier family 34 (sodium phosphate), member 1
Disease_progression
ISS
17
15,262,929
15,277,902
RGD:7242943
RGD
G
Spp1
secreted phosphoprotein 1
ISS
RGD:6903264
RGD
G
Tek
TEK tyrosine kinase, endothelial
IEP
5
115,047,195
115,196,172
RGD:1601494
RGD
G
Thbd
thrombomodulin
IPM
3
137,158,955
137,162,607
RGD:5684994
RGD
G
Thbd
thrombomodulin
ISS
3
137,158,955
137,162,607
RGD:5685010
RGD
G
Tlr2
toll-like receptor 2
ISS
2
175,607,990
175,613,992
RGD:7207898
RGD
G
Tlr4
toll-like receptor 4
Treatment
IED
5
83,564,100
83,577,735
RGD:6892690
RGD
G
Tlr4
toll-like receptor 4
ISS
5
83,564,100
83,577,735
RGD:7241084
RGD
G
Tlr4
toll-like receptor 4
ISS
5
83,564,100
83,577,735
RGD:7207898
RGD
G
Uts2r
urotensin 2 receptor
IPM
10
110,394,782
110,395,942
RGD:2306847
RGD
G
Wnt4
wingless-type MMTV integration site family, member 4
IED
5
156,064,371
156,083,198
RGD:727218
RGD
Contrast-Induced Nephropathy
G
Crp
C-reactive protein, pentraxin-related
ISS
13
88,702,243
88,703,153
RGD:6909166
RGD
G
Il1b
interleukin 1 beta
IED
3
116,964,422
116,970,867
RGD:7175334
RGD
G
Mpo
myeloperoxidase
IED
10
76,085,872
76,097,012
RGD:6909183
RGD
Kidney Reperfusion Injury
G
Aldh2
aldehyde dehydrogenase 2 family (mitochondrial)
ISS
12
36,081,778
36,116,445
RGD:7241603
RGD
G
Anxa5
annexin A5
ISS
2
122,949,210
122,979,757
RGD:7242028
RGD
G
Apoa1
apolipoprotein A-I
Treatment
ISS
RGD:7241574
RGD
G
Bdkrb1
bradykinin receptor B1
ISS
6
129,760,129
129,762,545
RGD:7241559
RGD
G
Calca
calcitonin-related polypeptide alpha
IPM
1
172,686,168
172,691,061
RGD:7204479
RGD
G
Cd14
CD14 molecule
ISS
18
29,374,593
29,376,190
RGD:7204444
RGD
G
Cfb
complement factor B
ISS
20
4,072,124
4,077,802
RGD:7242709
RGD
G
Cfb
complement factor B
ISS
20
4,072,124
4,077,802
RGD:7242734
RGD
G
Ciita
class II, major histocompatibility complex, transactivator
ISS
10
5,087,174
5,133,418
RGD:7242896
RGD
G
Ctla4
cytotoxic T-lymphocyte-associated protein 4
ISS
9
59,495,773
59,501,300
RGD:7204675
RGD
G
Ctla4
cytotoxic T-lymphocyte-associated protein 4
ISS
9
59,495,773
59,501,300
RGD:7204727
RGD
G
Fga
fibrinogen alpha chain
IEP
2
174,737,640
174,753,598
RGD:7175292
RGD
G
Fgb
fibrinogen beta chain
Treatment
ISS
2
174,768,193
174,775,102
RGD:7175292
RGD
G
Fgb
fibrinogen beta chain
IEP
2
174,768,193
174,775,102
RGD:7175292
RGD
G
Fgg
fibrinogen gamma chain
IEP
2
174,727,312
174,734,594
RGD:7175292
RGD
G
Fn1
fibronectin 1
IEP
9
70,702,181
70,771,155
RGD:7205629
RGD
G
Fos
FBJ osteosarcoma oncogene
ISS
6
109,559,135
109,562,001
RGD:7242184
RGD
G
Glo1
glyoxalase 1
IPM
20
8,900,984
8,919,001
RGD:7242566
RGD
G
Hspa8
heat shock 70kDa protein 8
IEP
8
43,784,035
43,787,760
RGD:7242788
RGD
G
Igf1r
insulin-like growth factor 1 receptor
IEP
1
122,704,976
122,990,007
RGD:7242905
RGD
G
Il1b
interleukin 1 beta
IED
3
116,964,422
116,970,867
RGD:7175501
RGD
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:6909149
RGD
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:6907101
RGD
G
Il1rn
interleukin 1 receptor antagonist
ISS
3
2,607,800
2,613,216
RGD:6907359
RGD
G
Itgb2
integrin, beta 2
IPM
20
11,446,521
11,485,009
RGD:6907073
RGD
G
Itgb2
integrin, beta 2
ISS
20
11,446,521
11,485,009
RGD:6907049
RGD
G
Lep
leptin
Resistance
IED
4
55,943,837
55,945,938
RGD:6909133
RGD
G
Mpo
myeloperoxidase
ISS
10
76,085,872
76,097,012
RGD:7174699
RGD
G
Mpo
myeloperoxidase
IEP
10
76,085,872
76,097,012
RGD:6909167
RGD
G
Myc
myelocytomatosis oncogene
IEP
7
98,953,142
98,958,060
RGD:7207777
RGD
G
Pkd2
polycystic kidney disease 2 (autosomal dominant)
IEP
14
6,349,519
6,392,988
RGD:1580868
RGD
G
Slc34a1
solute carrier family 34 (sodium phosphate), member 1
IEP
17
15,262,929
15,277,902
RGD:2311304
RGD
G
Tlr2
toll-like receptor 2
ISS
2
175,607,990
175,613,992
RGD:7240552
RGD
G
Tlr2
toll-like receptor 2
Treatment
IED
2
175,607,990
175,613,992
RGD:7207892
RGD
G
Tlr2
toll-like receptor 2
Severity
ISS
2
175,607,990
175,613,992
RGD:7207896
RGD
G
Tlr2
toll-like receptor 2
Treatment
ISS
2
175,607,990
175,613,992
RGD:7207894
RGD
G
Tlr2
toll-like receptor 2
ISS
2
175,607,990
175,613,992
RGD:7241087
RGD
G
Tlr4
toll-like receptor 4
ISS
5
83,564,100
83,577,735
RGD:7240552
RGD
G
Tlr4
toll-like receptor 4
ISS
5
83,564,100
83,577,735
RGD:7241087
RGD
G
Tlr4
toll-like receptor 4
Treatment
IED
5
83,564,100
83,577,735
RGD:7207892
RGD
G
Vcam1
vascular cell adhesion molecule 1
IEP
2
212,277,654
212,297,376
RGD:7240507
RGD
Kidney Tubular Necrosis, Acute
G
Ak4
adenylate kinase 4
IEP
5
122,062,872
122,119,335
RGD:5134352
RGD
G
Ciita
class II, major histocompatibility complex, transactivator
ISS
10
5,087,174
5,133,418
RGD:7242901
RGD
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