ONTOLOGY REPORT - ANNOTATIONS
Term: Ovarian Neoplasms
Accession: RDO:0001423
browse the term
Definition: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Synonyms: exact_synonym: Cancer of Ovary; Cancer of the Ovary; OVARIAN CANCER, EPITHELIAL; OVARIAN CANCER, SUSCEPTIBILITY TO, 1; OVCAS1; Ovarian Cancer; Ovarian Cancers; Ovarian Neoplasm; Ovary Cancer; Ovary Cancers; Ovary Neoplasm; Ovary Neoplasms
primary_id: MESH:D010051
alt_id: OMIM:167000 ; OMIM:192090 ; OMIM:607893
Ovarian Neoplasms
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Disease_progression
ISS
4
21,709,855
21,796,628
RGD:2315556
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
Susceptibility
ISS
6
137,640,482
137,657,552
RGD:1643334
RGD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
ISS
6
137,640,482
137,657,552
RGD:2313763
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
ISS
1
82,686,233
82,726,544
RGD:2290476
RGD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
ISS
1
82,686,233
82,726,544
RGD:2315603
RGD
G
Amh
anti-Mullerian hormone
ISS
7
10,417,325
10,419,673
RGD:2315638
RGD
G
Amh
anti-Mullerian hormone
IPM
7
10,417,325
10,419,673
RGD:2315652
RGD
G
Amhr2
anti-Mullerian hormone receptor, type II
ISS
7
141,203,832
141,212,653
RGD:2315638
RGD
G
Ang
angiogenin, ribonuclease, RNase A family, 5
ISS
15
27,083,089
27,083,526
RGD:2317660
RGD
G
Angpt1
angiopoietin 1
ISS
7
78,195,504
78,451,471
RGD:2293864
RGD
G
Anxa7
annexin A7
ISS
15
4,047,956
4,075,981
RGD:2292654
RGD
G
Apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
ISS
15
26,904,124
26,906,224
RGD:2315656
RGD
G
Apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
ISS
15
26,904,124
26,906,224
RGD:2315663
RGD
G
Areg
amphiregulin
ISS
14
18,466,313
18,475,571
RGD:1578721
RGD
G
Atp7b
ATPase, Cu++ transporting, beta polypeptide
Severity
ISS
16
74,607,988
74,680,080
RGD:2298865
RGD
G
Aurka
aurora kinase A
Susceptibility
ISS
3
163,270,479
163,284,506
RGD:2293884
RGD
G
Aurka
aurora kinase A
Disease_progression
ISS
3
163,270,479
163,284,506
RGD:2293872
RGD
G
Bard1
BRCA1 associated RING domain 1
ISS
9
70,120,151
70,198,591
RGD:2315727
RGD
G
Bcl2
B-cell CLL/lymphoma 2
Severity
ISS
13
12,730,736
12,905,108
RGD:2298897
RGD
G
Bcl2l1
Bcl2-like 1
ISS
3
143,129,087
143,180,199
RGD:1643478
RGD
G
Birc5
baculoviral IAP repeat-containing 5
Disease_progression
ISS
RGD:2298935
RGD
G
Birc5
baculoviral IAP repeat-containing 5
Disease_progression
ISS
RGD:2298936
RGD
G
Bmp7
bone morphogenetic protein 7
ISS
3
163,723,429
163,799,567
RGD:2289032
RGD
G
Braf
v-raf murine sarcoma viral oncogene homolog B1
ISS
4
67,117,759
67,243,058
RGD:2298686
RGD
G
Braf
v-raf murine sarcoma viral oncogene homolog B1
ISS
4
67,117,759
67,243,058
RGD:2315855
RGD
G
Brca1
breast cancer 1, early onset
ISS
10
90,513,630
90,572,676
RGD:734656
RGD
G
Brca1
breast cancer 1, early onset
Susceptibility
ISS
10
90,513,630
90,572,676
RGD:2293152
RGD
G
Brca2
breast cancer 2, early onset
Disease_progression
ISS
12
4,282,952
4,323,693
RGD:2289046
RGD
G
Brca2
breast cancer 2, early onset
Susceptibility
IAGP
12
4,282,952
4,323,693
RGD:1599505
RGD
G
Bsg
basigin (Ok blood group)
ISS
7
11,507,914
11,515,132
RGD:2289053
RGD
G
Btg1
B-cell translocation gene 1, anti-proliferative
ISS
7
34,029,300
34,031,557
RGD:2298943
RGD
G
Cadm1
cell adhesion molecule 1
Severity
ISS
8
50,765,645
51,108,962
RGD:2296030
RGD
G
Casp6
caspase 6
ISS
2
227,361,538
227,373,844
RGD:2301336
RGD
G
Cav1
caveolin 1, caveolae protein
ISS
4
42,956,102
42,989,057
RGD:2289113
RGD
G
Ccl5
chemokine (C-C motif) ligand 5
Severity
ISS
10
71,605,791
71,610,330
RGD:4891397
RGD
G
Ccnb1
cyclin B1
ISS
2
31,574,600
31,581,784
RGD:2315936
RGD
G
Ccnd1
cyclin D1
IPM
1
205,357,235
205,366,757
RGD:2296036
RGD
G
Ccnd2
cyclin D2
Disease_progression
ISS
4
163,523,817
163,546,501
RGD:2296038
RGD
G
Ccnd3
cyclin D3
Disease_progression
ISS
RGD:2316011
RGD
G
Ccne1
cyclin E1
Disease_progression
ISS
1
90,568,189
90,577,426
RGD:2296042
RGD
G
Ccne1
cyclin E1
IEP
1
90,568,189
90,577,426
RGD:2289335
RGD
G
Ccne1
cyclin E1
Disease_progression
ISS
1
90,568,189
90,577,426
RGD:2289287
RGD
G
Ccr3
chemokine (C-C motif) receptor 3
Disease_progression
ISS
8
128,759,943
128,769,341
RGD:6893445
RGD
G
Ccr5
chemokine (C-C motif) receptor 5
ISS
8
128,907,157
128,912,272
RGD:4892092
RGD
G
Cd40lg
CD40 ligand
Disease_progression
ISS
X
141,925,019
141,937,183
RGD:4891397
RGD
G
Cd44
Cd44 molecule
ISS
3
88,022,962
88,110,352
RGD:2289345
RGD
G
Cd46
CD46 molecule, complement regulatory protein
ISS
13
110,972,812
111,003,407
RGD:2306066
RGD
G
Cd46
CD46 molecule, complement regulatory protein
ISS
13
110,972,812
111,003,407
RGD:2306067
RGD
G
Cd46
CD46 molecule, complement regulatory protein
Disease_progression
ISS
13
110,972,812
111,003,407
RGD:2306065
RGD
G
Cd59
CD59 molecule, complement regulatory protein
ISS
3
89,243,600
89,245,129
RGD:2306066
RGD
G
Cd59
CD59 molecule, complement regulatory protein
ISS
3
89,243,600
89,245,129
RGD:2326189
RGD
G
Cd82
Cd82 molecule
Disease_progression
IEP
3
77,831,771
77,875,764
RGD:2289405
RGD
G
Cd9
CD9 molecule
Disease_progression
ISS
4
162,279,462
162,312,889
RGD:2289405
RGD
G
Cdh1
cadherin 1
ISS
19
36,442,693
36,512,091
RGD:2289497
RGD
G
Cdh1
cadherin 1
Susceptibility
ISS
19
36,442,693
36,512,091
RGD:2289494
RGD
G
Cdh1
cadherin 1
ISS
19
36,442,693
36,512,091
RGD:7240710
OMIM
G
Cdh13
cadherin 13
ISS
19
48,507,173
49,575,123
RGD:2298987
RGD
G
Cdk2
cyclin dependent kinase 2
Disease_progression
ISS
7
2,000,196
2,007,682
RGD:2298988
RGD
G
Cdk2
cyclin dependent kinase 2
ISS
7
2,000,196
2,007,682
RGD:2298989
RGD
G
Cdk4
cyclin-dependent kinase 4
ISS
RGD:2299054
RGD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
ISS
20
7,376,325
7,386,778
RGD:2289661
RGD
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
ISS
4
171,841,705
171,846,506
RGD:2293610
RGD
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
Disease_progression
ISS
4
171,841,705
171,846,506
RGD:2299089
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
Disease_progression
ISS
5
108,908,749
108,916,380
RGD:2296051
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISS
5
108,908,749
108,916,380
RGD:2296056
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
Severity
ISS
5
108,908,749
108,916,380
RGD:2296050
RGD
G
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
ISS
5
108,939,669
108,945,293
RGD:2296065
RGD
G
Chek2
checkpoint kinase 2
Susceptibility
ISS
12
45,933,900
45,965,427
RGD:2298482
RGD
G
Chek2
checkpoint kinase 2
Susceptibility
ISS
12
45,933,900
45,965,427
RGD:2289706
RGD
G
Chi3l1
chitinase 3-like 1 (cartilage glycoprotein-39)
Severity
ISS
13
47,139,658
47,147,591
RGD:4892638
RGD
G
Cldn4
claudin 4
ISS
12
22,816,134
22,817,932
RGD:2317583
RGD
G
Comt
catechol-O-methyltransferase
Susceptibility
ISS
11
84,561,591
84,581,713
RGD:2289724
RGD
G
Comt
catechol-O-methyltransferase
ISS
11
84,561,591
84,581,713
RGD:2289722
RGD
G
Comt
catechol-O-methyltransferase
No_Association
ISS
11
84,561,591
84,581,713
RGD:2289725
RGD
G
Ctgf
connective tissue growth factor
ISS
1
21,327,099
21,330,215
RGD:2314512
RGD
G
Ctnna1
catenin (cadherin-associated protein), alpha 1, 102kDa
ISS
18
27,629,915
27,769,360
RGD:2289798
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
Disease_progression
ISS
8
125,978,161
125,987,670
RGD:2298487
RGD
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
ISS
RGD:2301045
RGD
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
ISS
8
61,439,062
61,447,861
RGD:2301045
RGD
G
Dusp1
dual specificity phosphatase 1
Disease_progression
ISS
10
16,942,913
16,945,696
RGD:2298695
RGD
G
Ebag9
estrogen receptor binding site associated, antigen, 9
Disease_progression
ISS
7
80,515,272
80,533,346
RGD:2289854
RGD
G
Edn1
endothelin 1
ISS
17
28,303,886
28,309,775
RGD:4144954
RGD
G
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
ISS
3
170,295,327
170,304,505
RGD:2303420
RGD
G
Egfr
epidermal growth factor receptor
Severity
ISS
14
97,617,358
97,788,211
RGD:5131867
RGD
G
Egfr
epidermal growth factor receptor
ISS
14
97,617,358
97,788,211
RGD:2298499
RGD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
ISS
10
87,219,157
87,242,919
RGD:2289928
RGD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
ISS
10
87,219,157
87,242,919
RGD:2298499
RGD
G
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
ISS
7
1,858,057
1,877,353
RGD:2298499
RGD
G
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Disease_progression
ISS
7
1,858,057
1,877,353
RGD:2298501
RGD
G
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
ISS
9
66,843,898
67,967,970
RGD:2298499
RGD
G
Esr1
estrogen receptor 1
IEP
1
35,523,680
35,759,891
RGD:2290042
RGD
G
F2
coagulation factor II
ISS
3
76,005,318
76,018,603
RGD:5147781
RGD
G
Fancf
Fanconi anemia, complementation group F
ISS
1
101,664,895
101,666,720
RGD:2290044
RGD
G
Fancf
Fanconi anemia, complementation group F
Disease_progression
ISS
1
101,664,895
101,666,720
RGD:2298507
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
Disease_progression
ISS
1
238,259,443
238,274,745
RGD:2290084
RGD
G
Fgf1
fibroblast growth factor 1 (acidic)
Disease_progression
ISS
18
31,785,480
31,806,452
RGD:2290288
RGD
G
Fgf2
fibroblast growth factor 2
Disease_progression
ISS
2
123,893,314
123,947,136
RGD:2290288
RGD
G
Fgf7
fibroblast growth factor 7
ISS
3
113,468,427
113,517,538
RGD:2289080
RGD
G
Fgf8
fibroblast growth factor 8
ISS
1
250,951,023
250,956,730
RGD:2289342
RGD
G
Fgfr2
fibroblast growth factor receptor 2
ISS
1
189,482,975
189,589,279
RGD:2289733
RGD
G
Fhit
fragile histidine triad
ISS
15
15,823,461
17,329,184
RGD:2289905
RGD
G
Figf
c-fos induced growth factor
Disease_progression
ISS
X
50,830,612
50,864,445
RGD:2315478
RGD
G
Flt1
FMS-related tyrosine kinase 1
ISS
12
7,858,092
8,035,966
RGD:2301254
RGD
G
Flt1
FMS-related tyrosine kinase 1
ISS
12
7,858,092
8,035,966
RGD:2289945
RGD
G
Flt1
FMS-related tyrosine kinase 1
ISS
12
7,858,092
8,035,966
RGD:2301253
RGD
G
Fshr
follicle stimulating hormone receptor
ISS
6
12,925,894
13,161,215
RGD:1601234
RGD
G
Ghrh
growth hormone releasing hormone
ISS
3
148,027,235
148,046,352
RGD:2289974
RGD
G
Ghrh
growth hormone releasing hormone
ISS
3
148,027,235
148,046,352
RGD:2301424
RGD
G
Gstm1
glutathione S-transferase mu 1
Disease_progression
ISS
2
203,575,444
203,580,821
RGD:2293830
RGD
G
Gstt1
glutathione S-transferase theta 1
Disease_progression
ISS
20
13,604,355
13,621,456
RGD:2293830
RGD
G
H19
H19, imprinted maternally expressed transcript (non-protein coding)
Disease_progression
ISS
1
202,822,925
202,825,601
RGD:2306182
RGD
G
Hdac1
histone deacetylase 1
Disease_progression
ISS
5
148,672,515
148,699,810
RGD:2306205
RGD
G
Hdac1
histone deacetylase 1
ISS
5
148,672,515
148,699,810
RGD:2306215
RGD
G
Hdac2
histone deacetylase 2
ISS
20
41,162,093
41,186,492
RGD:2306215
RGD
G
Hdac2
histone deacetylase 2
Disease_progression
ISS
20
41,162,093
41,186,492
RGD:2306205
RGD
G
Hdac3
histone deacetylase 3
ISS
18
30,857,209
30,875,986
RGD:2306215
RGD
G
Hdac3
histone deacetylase 3
Disease_progression
ISS
18
30,857,209
30,875,986
RGD:2306205
RGD
G
Hif1a
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Disease_progression
ISS
6
96,419,024
96,463,891
RGD:2306225
RGD
G
Hmga2
high mobility group AT-hook 2
ISS
7
59,638,555
59,753,791
RGD:5147841
RGD
G
Htra2
HtrA serine peptidase 2
ISS
4
117,262,206
117,265,368
RGD:5688746
RGD
G
Igfbp3
insulin-like growth factor binding protein 3
ISS
14
87,959,153
87,967,085
RGD:2301467
RGD
G
Igfbp3
insulin-like growth factor binding protein 3
Disease_progression
ISS
14
87,959,153
87,967,085
RGD:2301468
RGD
G
Il10
interleukin 10
ISS
13
43,953,900
43,957,766
RGD:2317660
RGD
G
Il13
interleukin 13
ISS
10
39,093,512
39,096,069
RGD:2290344
RGD
G
Inha
inhibin alpha
ISS
9
74,781,223
74,784,124
RGD:2290383
RGD
G
Itga8
integrin, alpha 8
ISS
17
86,427,191
86,649,268
RGD:2302241
RGD
G
Jup
junction plakoglobin
ISS
10
89,307,938
89,335,254
RGD:2291881
RGD
G
Kdr
kinase insert domain receptor
ISS
RGD:2291926
RGD
G
Kiss1
KiSS-1 metastasis-suppressor
Disease_progression
ISS
13
46,244,786
46,247,288
RGD:2302169
RGD
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Disease_progression
ISS
14
34,906,043
34,984,819
RGD:2292422
RGD
G
Klk10
kallikrein related-peptidase 10
Disease_progression
ISS
1
94,210,924
94,214,301
RGD:2314846
RGD
G
Klk13
kallikrein related-peptidase 13
ISS
1
94,133,589
94,145,208
RGD:2314862
RGD
G
Klk4
kallikrein-related peptidase 4
Severity
ISS
1
94,321,663
94,327,488
RGD:2314856
RGD
G
Klk6
kallikrein related-peptidase 6
ISS
1
94,254,350
94,261,500
RGD:2314855
RGD
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ISS
4
182,869,242
182,895,106
RGD:2314911
RGD
G
L1cam
L1 cell adhesion molecule
Severity
ISS
X
159,784,792
159,801,553
RGD:6483445
RGD
G
L1cam
L1 cell adhesion molecule
ISS
X
159,784,792
159,801,553
RGD:6483449
RGD
G
Lef1
lymphoid enhancer binding factor 1
ISS
2
228,550,263
228,673,131
RGD:2298717
RGD
G
Letmd1
LETM1 domain containing 1
ISS
7
139,172,373
139,181,857
RGD:2314918
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2289157
RGD
G
Lnpep
leucyl/cystinyl aminopeptidase
Disease_progression
ISS
1
56,063,361
56,151,257
RGD:2314924
RGD
G
Lnpep
leucyl/cystinyl aminopeptidase
ISS
1
56,063,361
56,151,257
RGD:2314920
RGD
G
Map2k1
mitogen activated protein kinase kinase 1
ISS
8
68,379,074
68,451,554
RGD:61657
RGD
G
Map2k1
mitogen activated protein kinase kinase 1
ISS
8
68,379,074
68,451,554
RGD:2306053
RGD
G
Map2k2
mitogen activated protein kinase kinase 2
ISS
7
10,074,654
10,094,003
RGD:2298686
RGD
G
Map2k4
mitogen activated protein kinase kinase 4
ISS
10
52,009,149
52,041,599
RGD:2293332
RGD
G
Map2k4
mitogen activated protein kinase kinase 4
Disease_progression
ISS
10
52,009,149
52,041,599
RGD:2293338
RGD
G
Map2k6
mitogen-activated protein kinase kinase 6
Disease_progression
ISS
10
99,859,684
99,974,446
RGD:2293338
RGD
G
Map2k7
mitogen activated protein kinase kinase 7
No_Association
ISS
12
1,545,407
1,552,353
RGD:2293338
RGD
G
Met
met proto-oncogene
ISS
4
43,134,183
43,211,355
RGD:2317612
RGD
G
Mgmt
O-6-methylguanine-DNA methyltransferase
ISS
1
196,629,366
196,866,937
RGD:2317693
RGD
G
Mgp
matrix Gla protein
ISS
4
173,910,595
173,913,917
RGD:2293586
RGD
G
Mmp1
matrix metallopeptidase 1 (interstitial collagenase)
ISS
8
4,333,773
4,354,284
RGD:7207020
RGD
G
Mmp13
matrix metallopeptidase 13
ISS
8
4,158,887
4,169,166
RGD:2306074
RGD
G
Mmp13
matrix metallopeptidase 13
Disease_progression
ISS
8
4,158,887
4,169,166
RGD:2306083
RGD
G
Mmp2
matrix metallopeptidase 2
Susceptibility
ISS
19
15,246,036
15,275,061
RGD:2298519
RGD
G
Mmp8
matrix metallopeptidase 8
Disease_progression
ISS
8
4,402,124
4,410,976
RGD:2306084
RGD
G
Msh2
mutS homolog 2 (E. coli)
ISS
6
11,199,906
11,258,350
RGD:2298950
RGD
G
Msln
mesothelin
ISS
10
15,017,162
15,022,823
RGD:2326057
RGD
G
Msln
mesothelin
ISS
10
15,017,162
15,022,823
RGD:2326062
RGD
G
Msr1
macrophage scavenger receptor 1
Disease_progression
ISS
16
56,278,223
56,345,472
RGD:2306128
RGD
G
Mt-cyb
mitochondrially encoded cytochrome b
ISS
MT
14,136
15,278
RGD:2298954
RGD
G
Mtus1
microtubule associated tumor suppressor 1
ISS
16
54,611,502
54,664,075
RGD:2317019
RGD
G
Muc16
mucin 16, cell surface associated
IEP
8
16,552,167
16,726,561
RGD:2325203
RGD
G
Myo6
myosin VI
Disease_progression
ISS
8
85,203,987
85,368,026
RGD:2314958
RGD
G
Nbn
nibrin
ISS
5
30,541,610
30,576,168
RGD:2298994
RGD
G
Ncoa4
nuclear receptor coactivator 4
ISS
16
7,642,116
7,662,460
RGD:2293537
RGD
G
Nme1
NME/NM23 nucleoside diphosphate kinase 1
Disease_progression
ISS
10
82,591,705
82,601,075
RGD:2299065
RGD
G
Nme1
NME/NM23 nucleoside diphosphate kinase 1
ISS
10
82,591,705
82,601,075
RGD:2299069
RGD
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
ISS
10
82,582,766
82,588,269
RGD:2299073
RGD
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISS
19
19,662,337
19,697,341
RGD:5131515
RGD
G
Nos3
nitric oxide synthase 3, endothelial cell
Disease_progression
ISS
4
6,158,847
6,179,441
RGD:2298575
RGD
G
Ovca2
ovarian tumor suppressor candidate 2
ISS
10
62,483,079
62,486,241
RGD:2302168
RGD
G
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
ISS
1
155,057,622
155,174,714
RGD:2299166
RGD
G
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
Severity
ISS
1
155,057,622
155,174,714
RGD:2299164
RGD
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
ISS
14
35,369,422
35,418,126
RGD:2298578
RGD
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
Disease_progression
ISS
14
35,369,422
35,418,126
RGD:2292199
RGD
G
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
ISS
18
57,014,475
57,053,581
RGD:2298578
RGD
G
Pebp1
phosphatidylethanolamine binding protein 1
ISS
12
40,491,393
40,495,593
RGD:2302866
RGD
G
Phb
prohibitin
No_Association
ISS
RGD:2292403
RGD
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:2290476
RGD
G
Pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
ISS
2
32,602,673
32,675,350
RGD:2290476
RGD
G
Plk1
polo-like kinase 1
Disease_progression
ISS
1
181,002,811
181,012,741
RGD:2299941
RGD
G
Plk3
polo-like kinase 3
Disease_progression
ISS
5
137,443,540
137,448,715
RGD:2299941
RGD
G
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
Disease_progression
ISS
12
11,004,507
11,028,754
RGD:2315028
RGD
G
Prkca
protein kinase C, alpha
Severity
ISS
10
97,367,196
97,638,910
RGD:2292460
RGD
G
Prkca
protein kinase C, alpha
ISS
10
97,367,196
97,638,910
RGD:2298671
RGD
G
Prkci
protein kinase C, iota
Disease_progression
ISS
2
116,739,625
116,801,084
RGD:2292460
RGD
G
Prss8
protease, serine, 8
ISS
1
187,210,556
187,215,072
RGD:2292486
RGD
G
Pten
phosphatase and tensin homolog
ISS
1
236,771,027
236,837,261
RGD:2289817
RGD
G
Ptges
prostaglandin E synthase
ISS
3
9,946,194
9,957,538
RGD:2300080
RGD
G
Ptgs1
prostaglandin-endoperoxide synthase 1
ISS
3
15,343,832
15,365,412
RGD:2300211
RGD
G
Ptgs1
prostaglandin-endoperoxide synthase 1
ISS
3
15,343,832
15,365,412
RGD:2300208
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
Disease_progression
ISS
13
64,427,288
64,432,978
RGD:2298936
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISS
13
64,427,288
64,432,978
RGD:2300209
RGD
G
Ptk2
protein tyrosine kinase 2
ISS
7
110,933,298
111,084,554
RGD:2292572
RGD
G
Ptk2
protein tyrosine kinase 2
ISS
7
110,933,298
111,084,554
RGD:2292563
RGD
G
Rad51
RAD51 homolog (S. cerevisiae)
Resistance
ISS
3
105,625,265
105,650,392
RGD:2298722
RGD
G
Rad51
RAD51 homolog (S. cerevisiae)
No_Association
ISS
3
105,625,265
105,650,392
RGD:2298723
RGD
G
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
ISS
8
112,798,863
112,810,004
RGD:2291977
RGD
G
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
Disease_progression
ISS
8
112,798,863
112,810,004
RGD:2299867
RGD
G
Rb1
retinoblastoma 1
Disease_progression
ISS
15
53,828,881
53,962,099
RGD:2296051
RGD
G
Rb1
retinoblastoma 1
Susceptibility
ISS
15
53,828,881
53,962,099
RGD:2299894
RGD
G
Rb1
retinoblastoma 1
Susceptibility
ISS
15
53,828,881
53,962,099
RGD:2299895
RGD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Disease_progression
ISS
1
208,262,669
208,273,148
RGD:2298752
RGD
G
Rhoa
ras homolog family member A
Disease_progression
ISS
RGD:2298873
RGD
G
Rhoc
ras homolog family member C
ISS
2
200,048,056
200,054,107
RGD:2298873
RGD
G
RT1-Db1
RT1 class II, locus Db1
ISS
20
4,671,489
4,681,058
RGD:2306229
RGD
G
Runx3
runt-related transcription factor 3
ISS
5
153,950,116
153,973,141
RGD:2302556
RGD
G
Sfn
stratifin
ISS
5
151,475,395
151,479,996
RGD:2299930
RGD
G
Sfn
stratifin
Disease_progression
ISS
5
151,475,395
151,479,996
RGD:2299933
RGD
G
Shmt1
serine hydroxymethyltransferase 1 (soluble)
ISS
10
46,936,605
46,964,779
RGD:2300329
RGD
G
Skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Disease_progression
ISS
2
58,769,164
58,797,229
RGD:2315042
RGD
G
Smad2
SMAD family member 2
ISS
18
73,180,520
73,241,707
RGD:2299967
RGD
G
Smad2
SMAD family member 2
ISS
18
73,180,520
73,241,707
RGD:2299974
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:2299976
RGD
G
Smad4
SMAD family member 4
ISS
18
70,432,705
70,461,541
RGD:2299979
RGD
G
Smad6
SMAD family member 6
ISS
8
68,144,395
68,214,652
RGD:2300008
RGD
G
Smad7
SMAD family member 7
ISS
18
72,294,803
72,323,354
RGD:2300008
RGD
G
Socs1
suppressor of cytokine signaling 1
ISS
10
4,819,971
4,820,609
RGD:2298907
RGD
G
Socs2
suppressor of cytokine signaling 2
ISS
7
32,605,714
32,608,323
RGD:2298907
RGD
G
Sod2
superoxide dismutase 2, mitochondrial
ISS
1
41,862,997
41,870,327
RGD:1581239
RGD
G
Sparc
secreted protein, acidic, cysteine-rich (osteonectin)
ISS
10
40,809,730
40,831,481
RGD:2300027
RGD
G
Sparc
secreted protein, acidic, cysteine-rich (osteonectin)
ISS
10
40,809,730
40,831,481
RGD:2300019
RGD
G
Spdef
SAM pointed domain containing ets transcription factor
Disease_progression
ISS
20
5,927,866
5,942,091
RGD:2298935
RGD
G
Spink1
serine peptidase inhibitor, Kazal type 1
Disease_progression
ISS
18
37,090,934
37,099,835
RGD:2300386
RGD
G
Spint1
serine peptidase inhibitor, Kunitz type 1
ISS
3
105,757,666
105,770,345
RGD:1581316
RGD
G
Spp1
secreted phosphoprotein 1
ISS
RGD:1581364
RGD
G
St14
suppression of tumorigenicity 14 (colon carcinoma)
ISS
8
30,916,769
30,932,214
RGD:2315091
RGD
G
Stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
ISS
10
89,821,078
89,872,970
RGD:2291931
RGD
G
Stk11
serine/threonine kinase 11
Susceptibility
ISS
7
11,086,760
11,103,522
RGD:2298556
RGD
G
Sult1a1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
ISS
1
185,829,205
185,832,725
RGD:2301045
RGD
G
Tbx3
T-box 3
ISS
12
38,155,494
38,166,670
RGD:2300329
RGD
G
Terc
telomerase RNA component
Disease_progression
ISS
2
117,234,446
117,234,833
RGD:2298557
RGD
G
Tert
telomerase reverse transcriptase
ISS
1
30,445,180
30,465,942
RGD:2291989
RGD
G
Tert
telomerase reverse transcriptase
ISS
1
30,445,180
30,465,942
RGD:2298564
RGD
G
Tff1
trefoil factor 1
ISS
20
9,526,674
9,530,534
RGD:2292004
RGD
G
Tff1
trefoil factor 1
ISS
20
9,526,674
9,530,534
RGD:2292003
RGD
G
Tfrc
transferrin receptor
ISS
11
69,976,258
69,998,098
RGD:2298574
RGD
G
Timp1
TIMP metallopeptidase inhibitor 1
Disease_progression
ISS
X
12,542,496
12,547,094
RGD:2298520
RGD
G
Timp3
TIMP metallopeptidase inhibitor 3
Disease_progression
ISS
7
19,677,144
19,727,072
RGD:2290414
RGD
G
Timp4
tissue inhibitor of metalloproteinase 4
Disease_progression
ISS
4
151,375,072
151,381,591
RGD:2290414
RGD
G
Tnf
tumor necrosis factor
Disease_progression
ISS
20
3,661,000
3,663,618
RGD:2315115
RGD
G
Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
ISS
15
50,138,439
50,163,254
RGD:2298524
RGD
G
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
Disease_progression
ISS
4
162,172,563
162,185,252
RGD:2315115
RGD
G
Tnfrsf1b
tumor necrosis factor receptor superfamily, member 1b
Disease_progression
ISS
5
163,666,541
163,697,484
RGD:2315115
RGD
G
Top2a
topoisomerase (DNA) II alpha
Disease_progression
ISS
10
87,771,337
87,800,960
RGD:2315125
RGD
G
Tp53
tumor protein p53
ISS
10
56,399,721
56,411,150
RGD:2290540
RGD
G
Tp53
tumor protein p53
IEA
10
56,399,721
56,411,150
RGD:1331525
RGD
G
Tp63
tumor protein p63
Disease_progression
ISS
11
76,900,622
77,200,251
RGD:2315432
RGD
G
Tp73
tumor protein p73
ISS
5
170,848,979
171,078,739
RGD:2291834
RGD
G
Tp73
tumor protein p73
Disease_progression
ISS
5
170,848,979
171,078,739
RGD:2298530
RGD
G
Tp73
tumor protein p73
ISS
5
170,848,979
171,078,739
RGD:2291833
RGD
G
Tsg101
tumor susceptibility gene 101
Disease_progression
ISS
1
97,445,040
97,475,141
RGD:2298534
RGD
G
Tymp
thymidine phosphorylase
Disease_progression
ISS
7
127,666,518
127,671,624
RGD:2293722
RGD
G
Tymp
thymidine phosphorylase
Disease_progression
ISS
7
127,666,518
127,671,624
RGD:2293721
RGD
G
Ube2i
ubiquitin-conjugating enzyme E2I
ISS
10
14,509,948
14,524,551
RGD:2301345
RGD
G
Ugt1a1
UDP glucuronosyltransferase 1 family, polypeptide A1
ISS
9
87,091,241
87,098,362
RGD:2315451
RGD
G
Utrn
utrophin
ISS
1
7,099,840
7,614,980
RGD:2300329
RGD
G
Vegfa
vascular endothelial growth factor A
Disease_progression
ISS
9
10,520,730
10,536,071
RGD:2315464
RGD
G
Vegfc
vascular endothelial growth factor C
Disease_progression
ISS
16
40,624,435
40,739,692
RGD:2315470
RGD
G
Wnt11
wingless-type MMTV integration site family, member 11
ISS
1
156,125,969
156,142,065
RGD:634517
RGD
G
Wnt2b
wingless-type MMTV integration site family, member 2B
ISS
2
200,218,630
200,233,002
RGD:634517
RGD
G
Wnt5a
wingless-type MMTV integration site family, member 5A
ISS
16
3,782,025
3,799,625
RGD:634517
RGD
G
Wt1
Wilms tumor 1
ISS
3
90,529,704
90,577,280
RGD:2315539
RGD
G
Xiap
X-linked inhibitor of apoptosis
ISS
X
3,011,520
3,047,798
RGD:2315847
RGD
S
BDII
TAS
RGD:1004
RGD
S
OM
Osborne-Mendel
TAS
RGD:1004
RGD
S
OM/N
Osborne-Mendel
TAS
RGD:1004
RGD
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
G
Brca1
breast cancer 1, early onset
ISS
10
90,513,630
90,572,676
RGD:7240710
OMIM
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
G
Brca2
breast cancer 2, early onset
ISS
12
4,282,952
4,323,693
RGD:7240710
OMIM
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
G
Rad51c
Rad51 homolog c (S. cerevisiae)
ISS
10
75,692,205
75,718,369
RGD:7240710
OMIM
Carcinoma, Endometrioid
G
Areg
amphiregulin
ISS
14
18,466,313
18,475,571
RGD:2289950
RGD
G
Atp7b
ATPase, Cu++ transporting, beta polypeptide
Disease_progression
ISS
16
74,607,988
74,680,080
RGD:2298864
RGD
G
Birc5
baculoviral IAP repeat-containing 5
ISS
RGD:2298940
RGD
G
Bmp4
bone morphogenetic protein 4
ISS
15
22,283,171
22,286,757
RGD:2296026
RGD
G
Car9
carbonic anhydrase 9
ISS
5
59,986,413
59,993,015
RGD:2298945
RGD
G
Ccne1
cyclin E1
ISS
1
90,568,189
90,577,426
RGD:2289230
RGD
G
Cdh1
cadherin 1
ISS
19
36,442,693
36,512,091
RGD:2296045
RGD
G
Cdk2
cyclin dependent kinase 2
Severity
ISS
7
2,000,196
2,007,682
RGD:2298990
RGD
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
ISS
4
171,841,705
171,846,506
RGD:2299091
RGD
G
Chek2
checkpoint kinase 2
Susceptibility
ISS
12
45,933,900
45,965,427
RGD:2293868
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
ISS
8
125,978,161
125,987,670
RGD:2289817
RGD
G
Egfr
epidermal growth factor receptor
ISS
14
97,617,358
97,788,211
RGD:2289950
RGD
G
Eno2
enolase 2, gamma, neuronal
ISS
4
160,891,003
160,897,723
RGD:2293737
RGD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
ISS
10
87,219,157
87,242,919
RGD:2289950
RGD
G
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
ISS
7
1,858,057
1,877,353
RGD:2289950
RGD
G
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
ISS
9
66,843,898
67,967,970
RGD:2289950
RGD
G
Fgfr2
fibroblast growth factor receptor 2
ISS
1
189,482,975
189,589,279
RGD:2289862
RGD
G
Igfbp3
insulin-like growth factor binding protein 3
Disease_progression
ISS
14
87,959,153
87,967,085
RGD:2301465
RGD
G
Inha
inhibin alpha
ISS
9
74,781,223
74,784,124
RGD:2290368
RGD
G
Inhba
inhibin beta-A
ISS
17
57,244,466
57,257,531
RGD:2301688
RGD
G
Kdr
kinase insert domain receptor
Severity
ISS
RGD:2291929
RGD
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ISS
4
182,869,242
182,895,106
RGD:2314910
RGD
G
Lnpep
leucyl/cystinyl aminopeptidase
ISS
1
56,063,361
56,151,257
RGD:2314922
RGD
G
Nkx2-1
NK2 homeobox 1
ISS
6
76,916,943
76,920,133
RGD:2290483
RGD
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
ISS
14
35,369,422
35,418,126
RGD:2298578
RGD
G
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
ISS
18
57,014,475
57,053,581
RGD:2298578
RGD
G
Pten
phosphatase and tensin homolog
ISS
1
236,771,027
236,837,261
RGD:2289817
RGD
G
Spp1
secreted phosphoprotein 1
ISS
RGD:1581360
RGD
G
St14
suppression of tumorigenicity 14 (colon carcinoma)
ISS
8
30,916,769
30,932,214
RGD:2315091
RGD
G
Wif1
Wnt inhibitory factor 1
ISS
7
60,330,517
60,400,697
RGD:2298535
RGD
Q
Edcs1
Endometrial carcinoma susceptibility QTL1
Susceptibility
IED
11
19,445,919
24,982,397
RGD:1599856
RGD
Q
Edcs2
Endometrial carcinoma susceptibility QTL2
Susceptibility
IED
12
7,382,953
27,853,771
RGD:1599856
RGD
Q
Edcs3
Endometrial carcinoma susceptibility QTL3
Susceptibility
IED
20
1,675,005
2,780,205
RGD:1599856
RGD
Q
Edcs4
Endometrial carcinoma susceptibility QTL 4
Susceptibility
IED
1
221,868,279
247,322,277
RGD:1599856
RGD
Q
Edcs5
Endometrial carcinoma susceptibility QTL 5
Susceptibility
IED
17
65,900,398
82,125,463
RGD:1599856
RGD
S
BDII/Ztm
Spontaneous
TAS
RGD:1599853
RGD
S
BDII/Ztm
Model
IAGP
RGD:1599853
RGD
Granulosa Cell Tumor
G
Amh
anti-Mullerian hormone
Disease_progression
ISS
7
10,417,325
10,419,673
RGD:2315639
RGD
G
Bmp4
bone morphogenetic protein 4
ISS
15
22,283,171
22,286,757
RGD:1643593
RGD
G
Ccnd2
cyclin D2
ISS
4
163,523,817
163,546,501
RGD:2289157
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISS
5
108,908,749
108,916,380
RGD:2296066
RGD
G
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
ISS
5
108,939,669
108,945,293
RGD:2296066
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
ISS
8
125,978,161
125,987,670
RGD:1643593
RGD
G
Fancf
Fanconi anemia, complementation group F
Disease_progression
ISS
1
101,664,895
101,666,720
RGD:2298508
RGD
G
Fhit
fragile histidine triad
ISS
15
15,823,461
17,329,184
RGD:2298508
RGD
G
Fshr
follicle stimulating hormone receptor
ISS
6
12,925,894
13,161,215
RGD:2289157
RGD
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
ISS
14
34,906,043
34,984,819
RGD:2302173
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2289157
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2302176
RGD
G
Prkar2b
protein kinase, cAMP dependent regulatory, type II beta
ISS
6
50,234,979
50,325,298
RGD:2289157
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISS
13
64,427,288
64,432,978
RGD:2289157
RGD
G
Sgk1
serum/glucocorticoid regulated kinase 1
ISS
1
23,501,257
23,506,651
RGD:2289157
RGD
G
Smad1
SMAD family member 1
ISS
19
30,348,886
30,409,345
RGD:2299978
RGD
G
Smad5
SMAD family member 5
ISS
17
13,814,164
13,824,358
RGD:2299978
RGD
G
St14
suppression of tumorigenicity 14 (colon carcinoma)
ISS
8
30,916,769
30,932,214
RGD:2315091
RGD
G
Vegfa
vascular endothelial growth factor A
ISS
9
10,520,730
10,536,071
RGD:2315463
RGD
G
Wif1
Wnt inhibitory factor 1
ISS
7
60,330,517
60,400,697
RGD:1643593
RGD
Leydig Cell Tumor
G
Cdk4
cyclin-dependent kinase 4
ISS
RGD:2293582
RGD
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
ISS
4
171,841,705
171,846,506
RGD:2293582
RGD
G
Cga
glycoprotein hormones, alpha polypeptide
ISS
5
51,538,259
51,550,324
RGD:2293633
RGD
G
Esr1
estrogen receptor 1
ISS
1
35,523,680
35,759,891
RGD:2290041
RGD
G
Flt1
FMS-related tyrosine kinase 1
ISS
12
7,858,092
8,035,966
RGD:2301251
RGD
G
Inha
inhibin alpha
IEP
9
74,781,223
74,784,124
RGD:2290379
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2302176
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2292537
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:7240710
OMIM
G
Pdgfa
platelet-derived growth factor alpha polypeptide
ISS
12
16,151,045
16,172,412
RGD:2298579
RGD
G
Pdgfb
platelet-derived growth factor beta polypeptide
ISS
7
118,244,385
118,262,021
RGD:2298579
RGD
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
ISS
14
35,369,422
35,418,126
RGD:2298579
RGD
G
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
ISS
14
35,369,422
35,418,126
RGD:2298580
RGD
G
Pdgfrb
platelet derived growth factor receptor, beta polypeptide
ISS
18
57,014,475
57,053,581
RGD:2298579
RGD
G
Prmt5
protein arginine methyltransferase 5
ISS
15
32,574,951
32,584,336
RGD:2299953
RGD
Sertoli Cell Tumor
G
Inha
inhibin alpha
ISS
9
74,781,223
74,784,124
RGD:2290369
RGD
Sertoli-Leydig Cell Tumor
G
Inha
inhibin alpha
ISS
9
74,781,223
74,784,124
RGD:2290367
RGD
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest
Path 1
Diseases
30466
Endocrine System Diseases
3500
Endocrine Gland Neoplasms
843
Ovarian Neoplasms
346
Achard-Thiers syndrome
0
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
1
Brenner Tumor
0
Cancer of the oviduct
0
Carcinoma, Endometrioid
37
Granulosa Cell Tumor +
20
Hereditary Breast and Ovarian Cancer Syndrome
0
Luteoma
0
Meigs Syndrome
0
Ovarian Fibromata
0
Ovarian Germ Cell Cancer
0
Ovarian epithelial cancer
0
Sertoli-Leydig Cell Tumor +
17
Teratoma, Ovarian
0
Thecoma
0
Path 2
Diseases
30466
Female Urogenital Diseases and Pregnancy Complications
4077
Female Urogenital Diseases
3876
Genital Diseases, Female
932
Adnexal Diseases
401
Ovarian Diseases
400
Ovarian Neoplasms
346
Achard-Thiers syndrome
0
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
1
Brenner Tumor
0
Cancer of the oviduct
0
Carcinoma, Endometrioid
37
Granulosa Cell Tumor +
20
Hereditary Breast and Ovarian Cancer Syndrome
0
Luteoma
0
Meigs Syndrome
0
Ovarian Fibromata
0
Ovarian Germ Cell Cancer
0
Ovarian epithelial cancer
0
Sertoli-Leydig Cell Tumor +
17
Teratoma, Ovarian
0
Thecoma
0