ONTOLOGY REPORT - ANNOTATIONS

Term:Fatty Liver
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Accession:RDO:0001271 term browser browse the term
Definition:Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
Synonyms:exact_synonym: Liver Steatoses;   Liver Steatosis;   Steatohepatitides;   Steatohepatitis;   Steatosis of Liver;   Visceral Steatosis
 primary_id: MESH:D005234

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Fatty Liver term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abca1 ATP-binding cassette, subfamily A (ABC1), member 1 GBrowse link IEP 5 70,493,357 70,583,729 RGD:1598534 RGD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 IEP RGD:1598602 RGD
G Abcc3 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 GBrowse link IEP 10 82,986,552 83,030,799 RGD:2301064 RGD
G Acaca acetyl-CoA carboxylase alpha GBrowse link IED 10 72,483,772 72,677,134 RGD:1625727 RGD
G Acacb acetyl-CoA carboxylase beta GBrowse link IED 12 43,388,679 43,492,993 RGD:1625727 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link IEP 11 79,908,291 79,911,065 RGD:1599139 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link ISS 11 79,908,291 79,911,065 RGD:5686883 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link ISS 11 79,908,291 79,911,065 RGD:5686674 RGD
G Adk adenosine kinase GBrowse link ISS 15 3,071,412 3,458,891 RGD:1300259 RGD
G Adrb2 adrenoceptor beta 2, surface GBrowse link ISS 18 58,174,958 58,177,000 RGD:1559320 RGD
G Alpl alkaline phosphatase, liver/bone/kidney GBrowse link ISS 5 156,501,739 156,558,727 RGD:1601177 RGD
G Angptl4 angiopoietin-like 4 GBrowse link ISS 7 16,261,623 16,267,852 RGD:1625354 RGD
G Apob apolipoprotein B GBrowse link IEP 6 31,508,060 31,548,083 RGD:2325770 RGD
G Cat catalase GBrowse link IEP 3 88,654,077 88,686,212 RGD:5130871 RGD
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link ISS 4 13,471,878 13,525,620 RGD:6893500 RGD
G Cps1 carbamoyl-phosphate synthetase 1 GBrowse link IEP 9 65,907,211 66,017,942 RGD:4144089 RGD
G Creb1 cAMP responsive element binding protein 1 GBrowse link ISS 9 63,170,785 63,234,727 RGD:734818 RGD
G Ctsb cathepsin B GBrowse link IEP 15 42,402,829 42,423,701 RGD:2315513 RGD
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 GBrowse link ISS 1 200,918,521 200,928,919 RGD:1626302 RGD
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 GBrowse link IEP 1 200,918,521 200,928,919 RGD:4892244 RGD
G Fabp1 fatty acid binding protein 1, liver GBrowse link Induced ISS 4 104,412,200 104,415,981 RGD:1626440 RGD
G Hadha hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit GBrowse link ISS 6 26,173,798 26,191,433 RGD:1599882 RGD
G Hfe hemochromatosis GBrowse link No_Association ISS 17 48,469,927 48,478,502 RGD:1601460 RGD
G Hfe hemochromatosis GBrowse link ISS 17 48,469,927 48,478,502 RGD:1601452 RGD
G Il10 interleukin 10 GBrowse link IEP 13 43,953,900 43,957,766 RGD:2308948 RGD
G Il13 interleukin 13 GBrowse link ISS 10 39,093,512 39,096,069 RGD:4145478 RGD
G Il13ra2 interleukin 13 receptor, alpha 2 GBrowse link IPM X 30,505,850 30,533,002 RGD:4145478 RGD
G Il18 interleukin 18 GBrowse link IED 8 53,936,584 53,943,228 RGD:4889416 RGD
G Il1b interleukin 1 beta GBrowse link IEP 3 116,964,422 116,970,867 RGD:1626661 RGD
G Il6 interleukin 6 GBrowse link ISS 4 456,799 461,376 RGD:2307258 RGD
G Il6 interleukin 6 GBrowse link IAGP 4 456,799 461,376 RGD:2307264 RGD
G Ins2 insulin 2 GBrowse link ISS 1 202,935,548 202,936,379 RGD:2311137 RGD
G Insig1 insulin induced gene 1 GBrowse link Severity ISS 4 2,577,468 2,585,682 RGD:2308857 RGD
G Insig1 insulin induced gene 1 GBrowse link IEP 4 2,577,468 2,585,682 RGD:2308857 RGD
G Insig2 insulin induced gene 2 GBrowse link Severity ISS 13 33,331,951 33,345,132 RGD:2308857 RGD
G Jak2 Janus kinase 2 GBrowse link ISS 1 232,915,995 232,974,763 RGD:6483019 RGD
G Keap1 Kelch-like ECH-associated protein 1 GBrowse link ISS 8 20,259,178 20,266,351 RGD:6893372 RGD
G Lep leptin GBrowse link ISS 4 55,943,837 55,945,938 RGD:2311137 RGD
G Mthfr methylenetetrahydrofolate reductase (NAD(P)H) GBrowse link ISS 5 165,112,850 165,126,885 RGD:1580580 RGD
G Mttp microsomal triglyceride transfer protein GBrowse link ISS 2 235,613,710 235,654,848 RGD:1625483 RGD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link ISS 3 58,366,693 58,394,116 RGD:6893372 RGD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link IED 2 233,091,013 233,187,501 RGD:5135028 RGD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link IEP 19 37,251,147 37,266,040 RGD:5133249 RGD
G Otc ornithine carbamoyltransferase GBrowse link IEP X 24,609,141 24,685,341 RGD:4144061 RGD
G Plin2 perilipin 2 GBrowse link ISS 5 105,718,496 105,732,817 RGD:1625752 RGD
G Ppara peroxisome proliferator activated receptor alpha GBrowse link ISS 7 123,729,774 123,807,090 RGD:5509939 RGD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link IED 4 151,492,220 151,617,331 RGD:1580685 RGD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link IEP 14 64,278,115 64,370,912 RGD:7242179 RGD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link ISS 14 64,278,115 64,370,912 RGD:7242012 RGD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link Treatment IED 14 64,278,115 64,370,912 RGD:7241844 RGD
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link ISS 2 54,327,821 54,360,462 RGD:6484544 RGD
G Prkcd protein kinase C, delta GBrowse link ISS 16 5,954,218 5,975,743 RGD:1642523 RGD
G Pten phosphatase and tensin homolog GBrowse link IEP 1 236,771,027 236,837,261 RGD:2292522 RGD
G Pten phosphatase and tensin homolog GBrowse link ISS 1 236,771,027 236,837,261 RGD:1302555 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link IPM 13 64,427,288 64,432,978 RGD:5135028 RGD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link IED 1 208,262,669 208,273,148 RGD:5135028 RGD
G Shc1 SHC (Src homology 2 domain containing) transforming protein 1 GBrowse link ISS 2 181,616,581 181,628,144 RGD:1642523 RGD
G Slc27a4 solute carrier family 27 (fatty acid transporter), member 4 GBrowse link IEP 3 8,791,504 8,802,884 RGD:1625640 RGD
G Slco1a4 solute carrier organic anion transporter family, member 1a4 Model IEP RGD:1598602 RGD
G Socs1 suppressor of cytokine signaling 1 GBrowse link ISS 10 4,819,971 4,820,609 RGD:1625677 RGD
G Socs3 suppressor of cytokine signaling 3 GBrowse link ISS 10 107,958,468 107,959,330 RGD:1625677 RGD
G Suox sulfite oxidase GBrowse link IEP 7 1,973,471 1,976,040 RGD:1600114 RGD
G Txn1 thioredoxin 1 GBrowse link IEP 5 75,921,365 75,933,595 RGD:2306156 RGD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link IEP 1 157,925,514 157,928,222 RGD:7204423 RGD
Q Hpcl2 Hepatic cholesterol level QTL 2 GBrowse link Susceptibility IAGP 10 46,483,646 100,090,301 RGD:1643359 RGD
S SHR-Tg(PEPCK-SREBF1)2Ipcv IED RGD:2313691 RGD
S SHR.BN-(D10Mgh3-D10Rat85)/Ipcv GBrowse link Resistance IED 10 48,994,688 100,090,454 RGD:1643359 RGD
S SHR.BN-(D10Mgh3-Srebf1)/Ipcv GBrowse link Susceptibility IAGP 10 46,461,684 100,090,454 RGD:1643359 RGD
Fatty Liver, Alcoholic term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link ISS 11 79,908,291 79,911,065 RGD:5686674 RGD
G Aldh2 aldehyde dehydrogenase 2 family (mitochondrial) GBrowse link IED 12 36,081,778 36,116,445 RGD:1599041 RGD
G Ctsb cathepsin B GBrowse link IEP 15 42,402,829 42,423,701 RGD:2315516 RGD
G Pemt phosphatidylethanolamine N-methyltransferase IEP RGD:1642369 RGD
G Serpinf1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 GBrowse link IEP 10 62,713,441 62,739,444 RGD:2312349 RGD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link IEP 1 41,862,997 41,870,327 RGD:1625694 RGD
G Stat4 signal transducer and activator of transcription 4 GBrowse link IEP 9 46,510,251 46,650,076 RGD:7207884 RGD
Non-alcoholic Fatty Liver Disease term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link IEP 11 79,908,291 79,911,065 RGD:5686355 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link Disease_progression ISS 11 79,908,291 79,911,065 RGD:5686810 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link ISS 11 79,908,291 79,911,065 RGD:5686660 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link IEP 11 79,908,291 79,911,065 RGD:5685373 RGD
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link ISS 11 79,908,291 79,911,065 RGD:5686841 RGD
G Alox15 arachidonate 15-lipoxygenase GBrowse link ISS 10 57,185,939 57,194,388 RGD:5509622 RGD
G Apoe apolipoprotein E GBrowse link IED 1 79,003,634 79,006,387 RGD:6904141 RGD
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link ISS 4 13,471,878 13,525,620 RGD:6893543 RGD
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link IEP 2 27,127,504 27,149,580 RGD:5508690 RGD
G Irs1 insulin receptor substrate 1 GBrowse link IEP 9 81,585,251 81,638,071 RGD:6483014 RGD
G Irs2 insulin receptor substrate 2 GBrowse link IEP 16 83,379,987 83,404,220 RGD:6483014 RGD
G Jak2 Janus kinase 2 GBrowse link IED 1 232,915,995 232,974,763 RGD:6483030 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link ISS 10 65,036,884 65,072,453 RGD:5509578 RGD
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) GBrowse link ISS 9 13,057,988 13,100,289 RGD:6482771 RGD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link IED 14 64,278,115 64,370,912 RGD:6484527 RGD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link Susceptibility ISS 14 64,278,115 64,370,912 RGD:7241847 RGD
G Retn resistin GBrowse link IEP 12 2,499,630 2,501,370 RGD:7207249 RGD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link IED 10 89,821,078 89,872,970 RGD:6483030 RGD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link Treatment IED 1 157,925,514 157,928,222 RGD:7175312 RGD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link IEP 1 157,925,514 157,928,222 RGD:7204434 RGD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link ISS 1 157,925,514 157,928,222 RGD:7204435 RGD
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  Diseases 30477
    Digestive System Diseases 2254
      Liver Diseases 688
        Fatty Liver 96
          Acute fatty liver of pregnancy 0
          Fatty Liver, Alcoholic 7
          Lipoatrophy with diabetes, hepatic steatosis, cardiomyopathy, and leukomelanodermic papules 0
          Non-alcoholic Fatty Liver Disease 21
          Reye Syndrome 0
          Visceral Steatosis, Congenital 0
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