ONTOLOGY REPORT - ANNOTATIONS
Term: Granulosa Cell Tumor
Accession: RDO:0000751
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Definition: A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Synonyms: exact_synonym: Cancer of Granulosa Cells; Granulosa Cell Cancer; Granulosa Cell Cancers; Granulosa Cell Tumors; Granulosa Cells Cancer; Granulosa Cells Cancers
primary_id: MESH:D006106
Granulosa Cell Tumor
G
Amh
anti-Mullerian hormone
Disease_progression
ISS
7
10,417,325
10,419,673
RGD:2315639
RGD
G
Bmp4
bone morphogenetic protein 4
ISS
15
22,283,171
22,286,757
RGD:1643593
RGD
G
Ccnd2
cyclin D2
ISS
4
163,523,817
163,546,501
RGD:2289157
RGD
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISS
5
108,908,749
108,916,380
RGD:2296066
RGD
G
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
ISS
5
108,939,669
108,945,293
RGD:2296066
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
ISS
8
125,978,161
125,987,670
RGD:1643593
RGD
G
Fancf
Fanconi anemia, complementation group F
Disease_progression
ISS
1
101,664,895
101,666,720
RGD:2298508
RGD
G
Fhit
fragile histidine triad
ISS
15
15,823,461
17,329,184
RGD:2298508
RGD
G
Fshr
follicle stimulating hormone receptor
ISS
6
12,925,894
13,161,215
RGD:2289157
RGD
G
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
ISS
14
34,906,043
34,984,819
RGD:2302173
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2289157
RGD
G
Lhcgr
luteinizing hormone/choriogonadotropin receptor
ISS
6
12,613,622
12,651,587
RGD:2302176
RGD
G
Prkar2b
protein kinase, cAMP dependent regulatory, type II beta
ISS
6
50,234,979
50,325,298
RGD:2289157
RGD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISS
13
64,427,288
64,432,978
RGD:2289157
RGD
G
Sgk1
serum/glucocorticoid regulated kinase 1
ISS
1
23,501,257
23,506,651
RGD:2289157
RGD
G
Smad1
SMAD family member 1
ISS
19
30,348,886
30,409,345
RGD:2299978
RGD
G
Smad5
SMAD family member 5
ISS
17
13,814,164
13,824,358
RGD:2299978
RGD
G
St14
suppression of tumorigenicity 14 (colon carcinoma)
ISS
8
30,916,769
30,932,214
RGD:2315091
RGD
G
Vegfa
vascular endothelial growth factor A
ISS
9
10,520,730
10,536,071
RGD:2315463
RGD
G
Wif1
Wnt inhibitory factor 1
ISS
7
60,330,517
60,400,697
RGD:1643593
RGD
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