ONTOLOGY REPORT - ANNOTATIONS


Term:Granulosa Cell Tumor
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Accession:RDO:0000751 term browser browse the term
Definition:A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Synonyms:exact_synonym: Cancer of Granulosa Cells;   Granulosa Cell Cancer;   Granulosa Cell Cancers;   Granulosa Cell Tumors;   Granulosa Cells Cancer;   Granulosa Cells Cancers
 primary_id: MESH:D006106


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Granulosa Cell Tumor term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Amh anti-Mullerian hormone GBrowse link Disease_progression ISS 7 10,417,325 10,419,673 RGD:2315639 RGD
G Bmp4 bone morphogenetic protein 4 GBrowse link ISS 15 22,283,171 22,286,757 RGD:1643593 RGD
G Ccnd2 cyclin D2 GBrowse link ISS 4 163,523,817 163,546,501 RGD:2289157 RGD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISS 5 108,908,749 108,916,380 RGD:2296066 RGD
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link ISS 5 108,939,669 108,945,293 RGD:2296066 RGD
G Ctnnb1 catenin (cadherin associated protein), beta 1 GBrowse link ISS 8 125,978,161 125,987,670 RGD:1643593 RGD
G Fancf Fanconi anemia, complementation group F GBrowse link Disease_progression ISS 1 101,664,895 101,666,720 RGD:2298508 RGD
G Fhit fragile histidine triad GBrowse link ISS 15 15,823,461 17,329,184 RGD:2298508 RGD
G Fshr follicle stimulating hormone receptor GBrowse link ISS 6 12,925,894 13,161,215 RGD:2289157 RGD
G Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link ISS 14 34,906,043 34,984,819 RGD:2302173 RGD
G Lhcgr luteinizing hormone/choriogonadotropin receptor GBrowse link ISS 6 12,613,622 12,651,587 RGD:2289157 RGD
G Lhcgr luteinizing hormone/choriogonadotropin receptor GBrowse link ISS 6 12,613,622 12,651,587 RGD:2302176 RGD
G Prkar2b protein kinase, cAMP dependent regulatory, type II beta GBrowse link ISS 6 50,234,979 50,325,298 RGD:2289157 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link ISS 13 64,427,288 64,432,978 RGD:2289157 RGD
G Sgk1 serum/glucocorticoid regulated kinase 1 GBrowse link ISS 1 23,501,257 23,506,651 RGD:2289157 RGD
G Smad1 SMAD family member 1 GBrowse link ISS 19 30,348,886 30,409,345 RGD:2299978 RGD
G Smad5 SMAD family member 5 GBrowse link ISS 17 13,814,164 13,824,358 RGD:2299978 RGD
G St14 suppression of tumorigenicity 14 (colon carcinoma) GBrowse link ISS 8 30,916,769 30,932,214 RGD:2315091 RGD
G Vegfa vascular endothelial growth factor A GBrowse link ISS 9 10,520,730 10,536,071 RGD:2315463 RGD
G Wif1 Wnt inhibitory factor 1 GBrowse link ISS 7 60,330,517 60,400,697 RGD:1643593 RGD

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Path 1
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  Diseases 30477
    Endocrine System Diseases 3504
      Endocrine Gland Neoplasms 843
        Ovarian Neoplasms 346
          Granulosa Cell Tumor 20
            Abrikosov's tumor 0
            Granulosa cell tumor of the ovary 0
Path 2
Term Annotations click to browse term
  Diseases 30477
    Female Urogenital Diseases and Pregnancy Complications 4090
      Female Urogenital Diseases 3887
        Genital Diseases, Female 931
          Adnexal Diseases 400
            Ovarian Diseases 399
              Ovarian Neoplasms 346
                Granulosa Cell Tumor 20
                  Abrikosov's tumor 0
                  Granulosa cell tumor of the ovary 0
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