ONTOLOGY REPORT - ANNOTATIONS

Term:Liver Failure, Acute
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Accession:RDO:0000601 term browser browse the term
Definition:A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Synonyms:exact_synonym: Acute Hepatic Failure;   Fulminant Hepatic Failure;   Fulminant Hepatic Failures;   Fulminant Liver Failure;   Fulminant Liver Failures;   Fulminating Hepatic Failure;   Fulminating Hepatic Failures;   Fulminating Liver Failure;   Fulminating Liver Failures
 primary_id: MESH:D017114

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Liver Failure, Acute term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cd14 CD14 molecule GBrowse link IEP 18 29,374,593 29,376,190 RGD:4144156 RGD
G Il1rn interleukin 1 receptor antagonist GBrowse link ISS 3 2,607,800 2,613,216 RGD:6909176 RGD
G Ins1 insulin 1 GBrowse link IEP 1 258,001,134 258,001,688 RGD:2298712 RGD
G Ltc4s leukotriene C4 synthase GBrowse link IEP 10 35,786,877 35,788,838 RGD:2302283 RGD
G Met met proto-oncogene GBrowse link IEP 4 43,134,183 43,211,355 RGD:2317515 RGD
G Mt-atp8 mitochondrially encoded ATP synthase 8 GBrowse link Disease_progression ISS MT 7,758 7,961 RGD:5490296 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IEP 10 65,036,884 65,072,453 RGD:5509102 RGD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link IEP 4 6,158,847 6,179,441 RGD:2292148 RGD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link IPM 13 64,427,288 64,432,978 RGD:2300286 RGD
G Thbd thrombomodulin GBrowse link IEP 3 137,158,955 137,162,607 RGD:1601654 RGD
G Tlr4 toll-like receptor 4 GBrowse link IEP 5 83,564,100 83,577,735 RGD:4144156 RGD
G Tnf tumor necrosis factor GBrowse link IEP 20 3,661,000 3,663,618 RGD:4144156 RGD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link IEP 1 157,925,514 157,928,222 RGD:7175313 RGD
LIVER FAILURE, INFANTILE, TRANSIENT term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Trmu tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase GBrowse link ISS 7 123,881,485 123,898,025 RGD:7240710 OMIM
G Trnt1 tRNA nucleotidyl transferase, CCA-adding, 1 GBrowse link ISS 4 142,124,815 142,138,391 RGD:7240710 OMIM
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  Diseases 30466
    Digestive System Diseases 2254
      Liver Diseases 689
        Hepatic Insufficiency 34
          Liver Failure 34
            Liver Failure, Acute 15
              LIVER FAILURE, INFANTILE, TRANSIENT 2
              Massive Hepatic Necrosis 0
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