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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:thyroid hormone biosynthetic pathway
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Accession:PW:0002521 term browser browse the term
Definition:The major thyroid hormones thyroxine (T4) or tetraidothyronine and triiodothyronine (T3) are the major thyroid hormones produced via processing of thyroglobulin precursor. T3 is the active hormone and is derived from T4 by the action of deiodinases.
Synonyms:related_synonym: SMP:00716


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thyroid hormone biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain ISO SMPDB SMP:00716 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain ISO SMPDB SMP:00716 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Duox1 dual oxidase 1 ISO SMPDB SMP:00716 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 ISO SMPDB SMP:00716 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Nox3 NADPH oxidase 3 ISO SMPDB SMP:00716 NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851 		JBrowse link
G Nox4 NADPH oxidase 4 ISO SMPDB SMP:00716 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 ISO SMPDB SMP:00716 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 ISO SMPDB SMP:00716 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tg thyroglobulin ISO SMPDB SMP:00716 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tpo thyroid peroxidase ISO SMPDB SMP:00716 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      peptide and protein metabolic pathway 78
        peptide and protein hormone metabolic pathway 62
          thyroglobulin processing pathway 10
            thyroid hormone biosynthetic pathway 10
paths to the root