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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:esomeprazole pharmacodynamics pathway
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Accession:PW:0002184 term browser browse the term
Definition:The pathway of esomeprazole-target interaction and of the biochemical or physiological responses to drug. Esomeprazole is a compound in the class of proton pump inhibitors used in the treatment of acid-related disorders. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00225


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esomeprazole pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp4a ATPase H+/K+ transporting subunit alpha ISO SMPDB SMP:00225 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844 		JBrowse link
G Atp4b ATPase H+/K+ transporting subunit beta ISO SMPDB SMP:00225 NCBI chr16:76,144,150...76,153,063
Ensembl chr16:76,144,150...76,153,063 		JBrowse link
G Car1 carbonic anhydrase 1 ISO SMPDB SMP:00225 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Cckbr cholecystokinin B receptor ISO SMPDB SMP:00225 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 ISO SMPDB SMP:00225 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Clic2 chloride intracellular channel 2 ISO SMPDB SMP:00225 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355 		JBrowse link
G Gast gastrin ISO SMPDB SMP:00225 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Hrh2 histamine receptor H 2 ISO SMPDB SMP:00225 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO SMPDB SMP:00225 NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
G Sst somatostatin ISO SMPDB SMP:00225 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Sstr4 somatostatin receptor 4 ISO SMPDB SMP:00225 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      alimentary tract and metabolism drug pathway 80
        proton pump inhibitor drug pathway 11
          esomeprazole drug pathway 11
            esomeprazole pharmacodynamics pathway 11
paths to the root