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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:altered mitochondrial autophagy pathway
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Accession:PW:0001958 term browser browse the term
Definition:A mitophagy pathway that deviates from what its normal course should be. Mitochondrial damage and altered mitophagy pathway have been implicated in neurodegenerative diseases associated with aging, such as Parkinson, Huntington and Alzheimer diseases.
Synonyms:related_synonym: altered mitophagy pathway
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show annotations for term's descendants           Sort by:
altered mitochondrial autophagy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pink1 PTEN induced kinase 1 ISO RGD PMID:24735649 RGD:10450527 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24735649 RGD:10450527 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      homeostasis pathway 1773
        mitochondria homeostasis pathway 112
          mitochondrial autophagy pathway 23
            altered mitochondrial autophagy pathway 2
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      cell death pathway 243
        programmed cell death pathway 243
          non-apoptotic cell death pathway 85
            cellular autophagy pathway 85
              altered cellular autophagy 2
                altered mitochondrial autophagy pathway 2
paths to the root