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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:valsartan pharmacodynamics pathway
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Accession:PW:0001689 term browser browse the term
Definition:The pathway of valsartan-target interaction and of the biochemical or physiological responses to drug. The drug is an antagonist of the angiotensin II receptor type 1. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00165



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valsartan pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO SMPDB SMP:00165 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Agt angiotensinogen ISO SMPDB SMP:00165 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO SMPDB SMP:00165 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ren renin ISO SMPDB SMP:00165 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      cardiovascular system drug pathway 184
        renin-angiotensin system drug pathway 10
          valsartan drug pathway 4
            valsartan pharmacodynamics pathway 4
paths to the root