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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:cisplatin response pathway
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Accession:PW:0001510 term browser browse the term
Definition:A pathway triggered by exposure to cisplatin, a widely used and very potent anti-cancer platinum containing drug. It is also the one with the most toxic side effects. Nephorotoxicity and ototoxicity are among the primary toxic side effects.
Synonyms:related_synonym: response to cisplatin
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cisplatin response pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 ISO RGD PMID:24278698 RGD:8548480 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a4 solute carrier family 22 member 4 TAS RGD PMID:24278698 RGD:8548480 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 ISO
IDA		 RGD PMID:24278698 PMID:23123662 RGD:8548480, RGD:8549769 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 ISO RGD PMID:24278698 RGD:8548480 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      cellular detoxification pathway 156
        toxin and toxicant response pathway 23
          platinum (Pt) containing drug response pathway 4
            cisplatin response pathway 4
paths to the root