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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:auditory mechanotransduction pathway
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Accession:PW:0001503 term browser browse the term
Definition:The auditory mechanotransduction pathway converts mechanical stimuli into electrical signaling that are processed by the brain and account for the perception of sound, gravity and movement. The inner ear contains the cochlea and the vestibule responsible for sound and movement mechanotransduction, respectively. The auditory mechanotransduction primarily depicts the sound generated responses by the hair cells in the organ of Corti.
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auditory mechanotransduction pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta ISO RGD PMID:20624897 RGD:8547669 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actg1 actin, gamma 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Cdh23 cadherin-related 23 ISO RGD PMID:19804752 PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419 		JBrowse link
G Espn espin ISO RGD PMID:19804752 PMID:20624897 RGD:8547667, RGD:8547669 NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256 		JBrowse link
G Myo15a myosin XVA ISO RGD PMID:19804752 RGD:8547667 NCBI chr10:45,277,619...45,335,953
Ensembl chr10:45,278,737...45,335,340 		JBrowse link
G Myo1c myosin 1C ISO RGD PMID:19804752 RGD:8547667 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myo3a myosin IIIA ISO RGD PMID:19804752 RGD:8547667 NCBI chr17:84,543,465...84,759,562
Ensembl chr17:84,543,552...84,759,042 		JBrowse link
G Myo6 myosin VI ISO RGD PMID:20624897 PMID:22715884 RGD:8547669, RGD:8547672 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Myo7a myosin VIIA ISO RGD PMID:19804752 PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157 		JBrowse link
G Otof otoferlin ISO RGD PMID:22715884 RGD:8547672 NCBI chr 6:25,928,018...26,024,631
Ensembl chr 6:25,928,055...26,024,631 		JBrowse link
G Pcdh15 protocadherin related 15 ISO RGD PMID:19804752 PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719 		JBrowse link
G Pls1 plastin 1 ISO RGD PMID:20624897 RGD:8547669 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195 		JBrowse link
G Pls3 plastin 3 ISO RGD PMID:20624897 RGD:8547669 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Ptprq protein tyrosine phosphatase, receptor type, Q ISO RGD PMID:20624897 RGD:8547669 NCBI chr 7:42,834,455...43,016,807
Ensembl chr 7:42,837,109...43,016,917 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 ISO RGD PMID:22715884 RGD:8547672 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Ush1c USH1 protein network component harmonin ISO RGD PMID:19804752 PMID:22177415 RGD:8547667, RGD:8547671 NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671 		JBrowse link
G Ush1g USH1 protein network component sans ISO RGD PMID:22177415 RGD:8547671 NCBI chr10:100,559,721...100,563,590
Ensembl chr10:100,557,629...100,563,590 		JBrowse link
G Ush2a usherin ISO RGD PMID:20624897 RGD:8547669 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922 		JBrowse link
G Whrn whirlin ISO RGD PMID:19804752 RGD:8547667 NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      mechanotransduction pathway 70
        auditory mechanotransduction pathway 20
          altered auditory mechanotransduction pathway 0
Path 2
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      signaling pathway pertinent to the brain and nervous system 465
        sensory system signaling pathway 79
          auditory mechanotransduction pathway 20
            altered auditory mechanotransduction pathway 0
paths to the root