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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:kynurenine metabolic pathway
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Accession:PW:0001282 term browser browse the term
Definition:Those enzymatic reactions involved in the synthesis, utilization or degradation of kynurenine, a product of tryptophan degradation pathway. Kynurenine and its metabolites play important roles in the nervous system and also in immunity.
Synonyms:related_synonym: kynurenine metabolic process
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kynurenine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase TAS RGD PMID:19826765 RGD:11081066 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase ISO RGD PMID:25773161 RGD:11062165 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
G Afmid arylformamidase ISO RGD PMID:25773161 RGD:11062165 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 TAS RGD PMID:19826765 RGD:11081066 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase ISO RGD PMID:25773161 RGD:11062165 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:25773161 PMID:26186743 PMID:32369456 RGD:11062165, RGD:11081068, RGD:39939073 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 ISO RGD PMID:25773161 RGD:11062165 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Kmo kynurenine 3-monooxygenase ISO RGD PMID:25773161 PMID:26589832 RGD:11062165, RGD:11081069 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 ISO RGD PMID:19826765 RGD:11081066 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 TAS RGD PMID:19826765 RGD:11081066 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227 		JBrowse link
G Kynu kynureninase ISO RGD PMID:25773161 RGD:11062165 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase ISO RGD PMID:25773161 PMID:27072164 RGD:11062165, RGD:11081067 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      amino acid metabolic pathway 308
        hydrophobic amino acid metabolic pathway 130
          tryptophan metabolic pathway 46
            tryptophan degradation pathway 12
              kynurenine metabolic pathway 12
paths to the root