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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:fatty acid elongation pathway
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Accession:PW:0001136 term browser browse the term
Definition:The C16 palmitate product of the fatty acid biosynthetic pathway can be esterifed to triacylglycerol or converted to longer chain saturated and unsaturated fatty acid molecules by elongases and desaturases, depending on the needs of the cell. The elongation pathway takes place in the endoplasmic reticulum or in the mitochondrion. Longer chain fatty acids are present in certain specialized tissues; for instance, myelin contains large amounts of C22 and C24 molecules.
Synonyms:related_synonym: fatty acid elongation


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fatty acid elongation pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 IEA
ISO		 KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEA KEGG rno:00062 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha IEA
ISO		 KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta IEA
ISO		 KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO SMPDB SMP:00054 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase IEA
ISO		 KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00054 rno:00062 NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048 		JBrowse link
G Ppt2 palmitoyl-protein thioesterase 2 IEA KEGG rno:00062 NCBI chr20:4,112,520...4,132,774
Ensembl chr20:4,122,463...4,132,774 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          fatty acid biosynthetic pathway 40
            fatty acid elongation pathway 9
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