ONTOLOGY REPORT - ANNOTATIONS

Term:aldosterone biosynthetic pathway
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Accession:PW:0000773 term browser browse the term
Definition:Aldosterone is a C21 mineralocorticoid produced in the outer zone, the zona glomerulosa, of the adrenal cortex from the cholesterol precursor. It plays important roles in the regulation of water and salt balance.
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aldosterone biosynthetic pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 GBrowse link ISS 8 61,793,976 61,805,308 RGD:4892309 RGD
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 GBrowse link ISS 7 112,977,395 112,984,080 RGD:4889549 RGD
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 GBrowse link TAS 7 113,043,365 113,049,779 RGD:4889549 RGD
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 GBrowse link ISS 20 4,125,357 4,128,518 RGD:4889549 RGD
G Fdx1 ferredoxin 1 GBrowse link ISS 8 55,291,396 55,310,507 RGD:2325883 RGD
G Fdxr ferredoxin reductase GBrowse link ISS 10 105,342,684 105,351,374 RGD:2325883 RGD
G Por P450 (cytochrome) oxidoreductase GBrowse link ISS 12 22,078,629 22,097,301 RGD:4892309 RGD
G Star steroidogenic acute regulatory protein GBrowse link ISS 16 70,642,580 70,647,203 RGD:2325883 RGD
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  Pathway Ontology 17140
    classic metabolic pathway 3638
      lipid metabolic pathway 813
        isoprenoid metabolic pathway 188
          isoprenoid biosynthetic pathway 155
            steroid biosynthetic pathway 155
              steroid hormone biosynthetic pathway 107
                C21-steroid hormone biosynthetic pathway 20
                  mineralocorticoid biosynthetic pathway 8
                    aldosterone biosynthetic pathway 8
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