ONTOLOGY REPORT - ANNOTATIONS

Term:anti-diabetic drug pathway
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Accession:PW:0000723 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics of anti-diabetic drugs such as repaglinide, nateglinide and sulfonylurea - inhibitors of ATP-dependent potassium channel. By blocking the channel they stimulate insulin secretion to lower blood glucose level. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
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  Pathway Ontology 17140
    drug pathway 19
      alimentary tract and metabolism drug pathway 0
        anti-diabetic drug pathway 0
          nateglinide pharmacokinetics pathway 0
          potassium channel inhibitors pharmacodynamics pathway 0
          repaglinide pharmacokinetics pathway 0
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