ONTOLOGY REPORT - ANNOTATIONS

Term:insulin secretion pathway
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Accession:PW:0000674 term browser browse the term
Definition:Insulin secretion by pancreatic beta-cells is an important aspect of glucose homeostasis. A major component of glucose stimulated insulin secretion is represented by the route dependent on the ATP sensitive potassium channels. However, other contributions are also likely to promote insulin secretion.
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insulin secretion pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 GBrowse link TAS 1 96,622,574 96,703,723 RGD:2311063 RGD
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit GBrowse link TAS 19 25,188,170 25,424,495 RGD:2311105 RGD
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit GBrowse link TAS 4 154,895,691 155,517,389 RGD:2311105 RGD
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit GBrowse link TAS 16 5,383,259 5,703,361 RGD:2311105 RGD
G Cdc42 cell division cycle 42 (GTP binding protein) GBrowse link ISS 5 156,106,123 156,143,040 RGD:2311087 RGD
G Gck glucokinase GBrowse link TAS 14 86,572,518 86,587,723 RGD:2311061 RGD
G Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 GBrowse link TAS 3 158,250,001 158,345,927 RGD:2311121 RGD
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link TAS 1 96,614,960 96,617,993 RGD:2311063 RGD
G Rab27a RAB27A, member RAS oncogene family GBrowse link ISS 8 77,798,830 77,861,090 RGD:2311087 RGD
G Rab3a RAB3A, member RAS oncogene family GBrowse link ISS 16 19,189,765 19,193,874 RGD:2311087 RGD
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 GBrowse link TAS 2 116,036,501 116,065,834 RGD:2311061 RGD
G Snap25 synaptosomal-associated protein 25 GBrowse link TAS 3 124,806,637 124,894,653 RGD:2311121 RGD
G Stx1a syntaxin 1A (brain) GBrowse link ISS 12 22,737,112 22,765,064 RGD:2311087 RGD
G Stxbp1 syntaxin binding protein 1 GBrowse link ISS 3 11,762,105 11,825,531 RGD:2311087 RGD
G Syt7 synaptotagmin VII GBrowse link IMP 1 212,876,675 212,935,373 RGD:2311143 RGD
G Syt7 synaptotagmin VII GBrowse link TAS 1 212,876,675 212,935,373 RGD:2311148 RGD
G Syt7_v1 synaptotagmin 7, variant 1 IMP RGD:2311143 RGD
G Syt9 synaptotagmin IX GBrowse link TAS 1 164,722,168 164,928,937 RGD:2311148 RGD
G Syt9 synaptotagmin IX GBrowse link IMP 1 164,722,168 164,928,937 RGD:2311147 RGD
G Unc13a unc-13 homolog A (C. elegans) GBrowse link ISS 16 18,827,405 18,872,461 RGD:2311087 RGD
G Vamp2 vesicle-associated membrane protein 2 GBrowse link ISS 10 55,848,264 55,852,132 RGD:2311087 RGD
altered insulin secretion pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 GBrowse link ISS 1 96,622,574 96,703,723 RGD:2313628 RGD
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link ISS 1 96,614,960 96,617,993 RGD:2313628 RGD
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link ISS 1 96,614,960 96,617,993 RGD:2313610 RGD
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  Pathway Ontology 17140
    regulatory pathway 5692
      homeostasis pathway 2069
        glucose homeostasis pathway 694
          insulin secretion pathway 24
            altered insulin secretion pathway 3
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