ONTOLOGY REPORT - ANNOTATIONS
Term: endometrial cancer pathway
Accession: PW:0000611
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Definition: Endometrial cancer affects the lining of the uterus, or endometrium. Hormonal and genetic alterations play a role in the development of this carcinoma type. Mutations in genes acting in several pathways have been associated with the condition and its types.
Synonyms: related_synonym: KEGG:05213; endometrial neoplasm pathway
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endometrial cancer pathway
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
IEA
6
137,640,482
137,657,552
RGD:6907045
KEGG
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
IEA
1
82,686,233
82,726,544
RGD:6907045
KEGG
G
Akt3
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
IEA
13
92,802,390
93,110,704
RGD:6907045
KEGG
G
Apc
adenomatous polyposis coli
IEA
18
26,732,147
26,790,383
RGD:6907045
KEGG
G
Apc2
adenomatosis polyposis coli 2
IEA
7
10,903,675
10,920,010
RGD:6907045
KEGG
G
Axin1
axin 1
IEA
10
15,409,373
15,462,726
RGD:6907045
KEGG
G
Axin2
axin 2
IEA
10
98,294,466
98,321,830
RGD:6907045
KEGG
G
Bad
BCL2-associated agonist of cell death
IEA
1
209,617,373
209,626,292
RGD:6907045
KEGG
G
Braf
v-raf murine sarcoma viral oncogene homolog B1
IEA
4
67,117,759
67,243,058
RGD:6907045
KEGG
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
IEA
5
160,704,234
160,721,796
RGD:6907045
KEGG
G
Ccnd1
cyclin D1
IEA
1
205,357,235
205,366,757
RGD:6907045
KEGG
G
Cdh1
cadherin 1
IEA
19
36,442,693
36,512,091
RGD:6907045
KEGG
G
Ctnna1
catenin (cadherin-associated protein), alpha 1, 102kDa
IEA
18
27,629,915
27,769,360
RGD:6907045
KEGG
G
Ctnna2
catenin (cadherin associated protein), alpha 2
IEA
4
110,747,551
111,922,482
RGD:6907045
KEGG
G
Ctnna3
catenin (cadherin associated protein), alpha 3
IEA
20
25,842,315
26,947,108
RGD:6907045
KEGG
G
Ctnnb1
catenin (cadherin associated protein), beta 1
ISS
8
125,978,161
125,987,670
RGD:4143515
RGD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
IEA
8
125,978,161
125,987,670
RGD:6907045
KEGG
G
Egf
epidermal growth factor
IEA
2
227,103,900
227,195,062
RGD:6907045
KEGG
G
Egfr
epidermal growth factor receptor
IEA
14
97,617,358
97,788,211
RGD:6907045
KEGG
G
Elk1
ELK1, member of ETS oncogene family
IEA
X
12,597,863
12,604,248
RGD:6907045
KEGG
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
ISS
10
87,219,157
87,242,919
RGD:4143515
RGD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
IEA
10
87,219,157
87,242,919
RGD:6907045
KEGG
G
Foxo3
forkhead box O3
IEA
20
46,171,784
46,262,818
RGD:6907045
KEGG
G
Grb2
growth factor receptor bound protein 2
IEA
10
105,722,014
105,818,649
RGD:6907045
KEGG
G
Gsk3b
glycogen synthase kinase 3 beta
IEA
11
64,284,731
64,428,698
RGD:6907045
KEGG
G
Hras
Harvey rat sarcoma virus oncogene
IEA
1
201,385,705
201,388,987
RGD:6907045
KEGG
G
Ilk
integrin-linked kinase
IEA
1
163,481,299
163,487,550
RGD:6907045
KEGG
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ISS
4
182,869,242
182,895,106
RGD:4143515
RGD
G
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
IEA
4
182,869,242
182,895,106
RGD:6907045
KEGG
G
Lef1
lymphoid enhancer binding factor 1
IEA
2
228,550,263
228,673,131
RGD:6907045
KEGG
G
Map2k1
mitogen activated protein kinase kinase 1
IEA
8
68,379,074
68,451,554
RGD:6907045
KEGG
G
Map2k2
mitogen activated protein kinase kinase 2
IEA
7
10,074,654
10,094,003
RGD:6907045
KEGG
G
Mapk1
mitogen activated protein kinase 1
IEA
11
85,968,732
86,030,387
RGD:6907045
KEGG
G
Mapk3
mitogen activated protein kinase 3
IEA
1
185,935,044
185,941,245
RGD:6907045
KEGG
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
ISS
8
115,616,396
115,653,471
RGD:4143515
RGD
G
Mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
IEA
8
115,616,396
115,653,471
RGD:6907045
KEGG
G
Myc
myelocytomatosis oncogene
IEA
7
98,953,142
98,958,060
RGD:6907045
KEGG
G
Nras
neuroblastoma ras oncogene
IEA
2
198,292,650
198,300,286
RGD:6907045
KEGG
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
IEA
10
13,329,708
13,394,080
RGD:6907045
KEGG
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISS
2
118,640,277
118,672,440
RGD:4143515
RGD
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
IEA
2
118,640,277
118,672,440
RGD:6907045
KEGG
G
Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
IEA
8
103,886,682
103,957,112
RGD:6907045
KEGG
G
Pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
IEA
5
166,735,274
166,761,189
RGD:6907045
KEGG
G
Pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
IEA
2
32,602,673
32,675,350
RGD:6907045
KEGG
G
Pik3r2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
IEA
16
19,171,101
19,179,650
RGD:6907045
KEGG
G
Pik3r3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
IEA
5
136,497,494
136,566,473
RGD:6907045
KEGG
G
Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
IEA
10
55,227,872
55,248,301
RGD:6907045
KEGG
G
Pten
phosphatase and tensin homolog
ISS
1
236,771,027
236,837,261
RGD:4143515
RGD
G
Pten
phosphatase and tensin homolog
IEA
1
236,771,027
236,837,261
RGD:6907045
KEGG
G
Raf1
v-raf-leukemia viral oncogene 1
IEA
4
151,752,583
151,775,609
RGD:6907045
KEGG
G
Sos1
Son of sevenless homolog 1 (Drosophila)
IEA
6
3,308,778
3,390,661
RGD:6907045
KEGG
G
Sos2
son of sevenless homolog 2 (Drosophila)
IEA
6
91,609,463
91,722,481
RGD:6907045
KEGG
G
Tcf3
transcription factor 3
IEA
7
10,791,311
10,813,613
RGD:6907045
KEGG
G
Tcf7
transcription factor 7 (T-cell specific, HMG-box)
IEA
10
37,686,862
37,716,831
RGD:6907045
KEGG
G
Tcf7l2
transcription factor 7-like 2 (T-cell specific, HMG-box)
IEA
1
262,031,823
262,226,710
RGD:6907045
KEGG
G
Tp53
tumor protein p53
ISS
10
56,399,721
56,411,150
RGD:4143515
RGD
G
Tp53
tumor protein p53
IEA
10
56,399,721
56,411,150
RGD:6907045
KEGG
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