ONTOLOGY REPORT - ANNOTATIONS
Term: eicosanoid signaling pathway
Accession: PW:0000565
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Definition: Eicosanoids are molecules derived from omega-3 or omega-6 fats that can act as hormones. The receptors are G protein coupled (GPCR0 or the nuclear peroxisome proliferator-activated receptor gamma.
Synonyms: related_synonym: PID:200082
eicosanoid signaling pathway
G
Adrbk1
adrenergic, beta, receptor kinase 1
ISO
1
206,873,002
206,892,868
RGD:6484113
PID
G
Adrbk2
adrenergic, beta, receptor kinase 2
ISO
RGD:6484113
PID
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
ISO
6
137,640,482
137,657,552
RGD:6484113
PID
G
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
ISO
1
80,209,459
80,226,353
RGD:6484113
PID
G
Arr3
arrestin 3, retinal (X-arrestin)
ISO
X
88,602,380
88,614,721
RGD:6484113
PID
G
Arrb2
arrestin, beta 2
ISO
10
57,244,071
57,284,166
RGD:6484113
PID
G
Blk
B lymphoid tyrosine kinase
ISO
15
42,643,847
42,682,793
RGD:6484113
PID
G
Dnm1
dynamin 1
ISO
3
11,434,778
11,478,452
RGD:6484113
PID
G
Egf
epidermal growth factor
ISO
2
227,103,900
227,195,062
RGD:6484113
PID
G
Egfr
epidermal growth factor receptor
ISO
14
97,617,358
97,788,211
RGD:6484113
PID
G
Fgr
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
ISO
5
152,119,455
152,147,057
RGD:6484113
PID
G
Fyn
FYN oncogene related to SRC, FGR, YES
ISO
20
43,501,853
43,695,567
RGD:6484113
PID
G
Gna11
guanine nucleotide binding protein, alpha 11
ISO
7
9,636,748
9,662,492
RGD:6484113
PID
G
Gna12
guanine nucleotide binding protein (G protein) alpha 12
ISO
12
14,275,708
14,354,843
RGD:6484113
PID
G
Gna13
guanine nucleotide binding protein (G protein), alpha 13
ISO
10
98,933,205
98,965,819
RGD:6484113
PID
G
Gna14
guanine nucleotide binding protein, alpha 14
ISO
1
219,906,120
219,983,252
RGD:6484113
PID
G
Gna15
guanine nucleotide binding protein, alpha 15
ISO
7
9,669,956
9,689,442
RGD:6484113
PID
G
Gnai2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
ISO
8
112,861,952
112,882,647
RGD:6484113
PID
G
Gnaq
guanine nucleotide binding protein (G protein), q polypeptide
ISO
1
219,520,998
219,764,401
RGD:6484113
PID
G
Gnb1
guanine nucleotide binding protein (G protein), beta polypeptide 1
ISO
5
172,341,135
172,386,772
RGD:6484113
PID
G
Gnb5
guanine nucleotide binding protein (G protein), beta 5
ISO
8
80,128,787
80,169,629
RGD:6484113
PID
G
Gng2
guanine nucleotide binding protein (G protein), gamma 2
ISO
RGD:6484113
PID
G
Hck
hemopoietic cell kinase
ISO
3
143,447,697
143,490,281
RGD:6484113
PID
G
Icam1
intercellular adhesion molecule 1
ISO
8
20,040,177
20,051,939
RGD:6484113
PID
G
Lck
lymphocyte-specific protein tyrosine kinase
ISO
5
148,707,505
148,718,296
RGD:6484113
PID
G
Lyn
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
ISO
5
16,933,111
17,054,564
RGD:6484113
PID
G
Mapk11
mitogen-activated protein kinase 11
ISO
7
127,444,055
127,449,990
RGD:6484113
PID
G
Mapk14
mitogen activated protein kinase 14
ISO
20
6,939,249
7,000,378
RGD:6484113
PID
G
Nos3
nitric oxide synthase 3, endothelial cell
ISO
4
6,158,847
6,179,441
RGD:6484113
PID
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
ISO
6
50,441,892
50,476,931
RGD:6484113
PID
G
Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
ISO
10
55,227,872
55,248,301
RGD:6484113
PID
G
Pik3r6
phosphoinositide-3-kinase, regulatory subunit 6
ISO
10
55,270,065
55,303,503
RGD:6484113
PID
G
Plcb2
phospholipase C, beta 2
ISO
3
105,203,524
105,223,342
RGD:6484113
PID
G
Prkaca
protein kinase, cAMP-dependent, catalytic, alpha
ISO
19
25,840,795
25,864,786
RGD:6484113
PID
G
Prkca
protein kinase C, alpha
ISO
10
97,367,196
97,638,910
RGD:6484113
PID
G
Prkcd
protein kinase C, delta
ISO
16
5,954,218
5,975,743
RGD:6484113
PID
G
Prkce
protein kinase C, epsilon
ISO
6
9,631,234
10,097,311
RGD:6484113
PID
G
Prkcg
protein kinase C, gamma
ISO
1
64,145,749
64,172,712
RGD:6484113
PID
G
Prkch
protein kinase C, eta
ISO
6
96,069,354
96,281,790
RGD:6484113
PID
G
Prkcq
protein kinase C, theta
ISO
17
78,486,998
78,566,741
RGD:6484113
PID
G
Prkcz
protein kinase C, zeta
ISO
5
172,061,825
172,172,793
RGD:6484113
PID
G
Prkg1
protein kinase, cGMP-dependent, type 1
ISO
1
234,420,597
235,765,375
RGD:6484113
PID
G
Ptgdr
prostaglandin D2 receptor
ISO
15
19,345,555
19,352,929
RGD:6484113
PID
G
Ptgir
prostaglandin I2 (prostacyclin) receptor (IP)
ISO
1
77,234,538
77,236,921
RGD:6484113
PID
G
Rab11a
RAB11a, member RAS oncogene family
ISO
8
68,931,925
68,979,514
RGD:6484113
PID
G
Rac1
ras-related C3 botulinum toxin substrate 1
ISO
12
11,380,314
11,400,531
RGD:6484113
PID
G
Rhoa
ras homolog family member A
ISO
RGD:6484113
PID
G
Rock1
Rho-associated coiled-coil containing protein kinase 1
ISO
18
1,391,751
1,511,865
RGD:6484113
PID
G
Sele
selectin E
ISO
13
79,813,455
79,822,845
RGD:6484113
PID
G
Slc9a3r1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
ISO
10
105,237,637
105,254,750
RGD:6484113
PID
G
Src
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
ISO
3
148,157,256
148,170,524
RGD:6484113
PID
G
Syk
spleen tyrosine kinase
ISO
17
18,440,672
18,498,001
RGD:6484113
PID
G
Tbxa2r
thromboxane A2 receptor
ISO
7
9,867,739
9,872,536
RGD:6484113
PID
G
Tgm2
transglutaminase 2, C polypeptide
ISO
3
148,832,866
148,862,385
RGD:6484113
PID
G
Vcam1
vascular cell adhesion molecule 1
ISO
2
212,277,654
212,297,376
RGD:6484113
PID
G
Yes1
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
ISO
9
112,516,831
112,564,072
RGD:6484113
PID
eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma
G
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
IEA
8
124,305,097
124,313,887
RGD:6907045
KEGG
G
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
IEA
8
124,110,413
124,118,950
RGD:6907045
KEGG
G
Acadl
acyl-CoA dehydrogenase, long chain
IEA
9
65,613,130
65,651,775
RGD:6907045
KEGG
G
Acadm
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
IEA
2
251,866,645
251,890,729
RGD:6907045
KEGG
G
Acox1
acyl-CoA oxidase 1, palmitoyl
IEA
10
106,281,977
106,319,382
RGD:6907045
KEGG
G
Acox2
acyl-CoA oxidase 2, branched chain
IEA
15
18,645,349
18,677,855
RGD:6907045
KEGG
G
Acox3
acyl-CoA oxidase 3, pristanoyl
IEA
14
80,769,000
80,809,809
RGD:6907045
KEGG
G
Acsbg1
acyl-CoA synthetase bubblegum family member 1
IEA
8
58,156,231
58,212,485
RGD:6907045
KEGG
G
Acsbg2
acyl-CoA synthetase bubblegum family member 2
IEA
RGD:6907045
KEGG
G
Acsl1
acyl-CoA synthetase long-chain family member 1
IEA
16
49,036,892
49,081,416
RGD:6907045
KEGG
G
Acsl3
acyl-CoA synthetase long-chain family member 3
IEA
9
78,083,239
78,106,933
RGD:6907045
KEGG
G
Acsl4
acyl-CoA synthetase long-chain family member 4
IEA
X
36,168,547
36,232,162
RGD:6907045
KEGG
G
Acsl5
acyl-CoA synthetase long-chain family member 5
IEA
1
261,554,383
261,599,373
RGD:6907045
KEGG
G
Acsl6
acyl-CoA synthetase long-chain family member 6
IEA
10
39,729,805
39,778,106
RGD:6907045
KEGG
G
Adipoq
adiponectin, C1Q and collagen domain containing
IEA
11
79,908,291
79,911,065
RGD:6907045
KEGG
G
Angptl4
angiopoietin-like 4
IEA
7
16,261,623
16,267,852
RGD:6907045
KEGG
G
Apoa1
apolipoprotein A-I
IEA
RGD:6907045
KEGG
G
Apoa2
apolipoprotein A-II
IEA
13
87,114,734
87,116,372
RGD:6907045
KEGG
G
Apoa5
apolipoprotein A-V
IEA
8
49,253,538
49,255,777
RGD:6907045
KEGG
G
Apoc3
apolipoprotein C-III
IEA
RGD:6907045
KEGG
G
Aqp7
aquaporin 7
IEA
5
58,433,731
58,447,853
RGD:6907045
KEGG
G
Cd36
CD36 molecule (thrombospondin receptor)
IEA
4
13,471,878
13,525,620
RGD:6907045
KEGG
G
Cpt1a
carnitine palmitoyltransferase 1a, liver
IEA
1
205,852,800
205,912,972
RGD:6907045
KEGG
G
Cpt1b
carnitine palmitoyltransferase 1b, muscle
IEA
7
127,737,129
127,746,179
RGD:6907045
KEGG
G
Cpt1c
carnitine palmitoyltransferase 1c
IEA
1
95,432,958
95,447,485
RGD:6907045
KEGG
G
Cpt2
carnitine palmitoyltransferase 2
IEA
5
129,007,685
129,025,501
RGD:6907045
KEGG
G
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
IEA
9
74,039,204
74,068,648
RGD:6907045
KEGG
G
Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
IEA
5
135,901,653
135,915,754
RGD:6907045
KEGG
G
Cyp4a2
cytochrome P450, family 4, subfamily a, polypeptide 2
IEA
5
135,765,673
135,773,006
RGD:6907045
KEGG
G
Cyp4a3
cytochrome P450, family 4, subfamily a, polypeptide 3
IEA
5
135,876,140
135,893,753
RGD:6907045
KEGG
G
Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
IEA
5
135,546,858
135,578,199
RGD:6907045
KEGG
G
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
IEA
5
19,707,159
19,716,856
RGD:6907045
KEGG
G
Cyp8b1
cytochrome P450, family 8, subfamily b, polypeptide 1
IEA
8
127,018,908
127,020,878
RGD:6907045
KEGG
G
Dbi
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
IEA
RGD:6907045
KEGG
G
Ehhadh
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
IEA
11
81,474,161
81,507,645
RGD:6907045
KEGG
G
Fabp1
fatty acid binding protein 1, liver
IEA
4
104,412,200
104,415,981
RGD:6907045
KEGG
G
Fabp2
fatty acid binding protein 2, intestinal
IEA
2
219,591,502
219,605,097
RGD:6907045
KEGG
G
Fabp3
fatty acid binding protein 3, muscle and heart
IEA
5
149,340,525
149,347,268
RGD:6907045
KEGG
G
Fabp4
fatty acid binding protein 4, adipocyte
IEA
2
93,536,133
93,540,734
RGD:6907045
KEGG
G
Fabp5
fatty acid binding protein 5, epidermal
IEA
RGD:6907045
KEGG
G
Fabp6
fatty acid binding protein 6, ileal
IEA
10
28,694,773
28,699,442
RGD:6907045
KEGG
G
Fabp7
fatty acid binding protein 7, brain
IEA
20
36,812,518
36,816,050
RGD:6907045
KEGG
G
Fads2
fatty acid desaturase 2
IEA
1
212,512,691
212,542,622
RGD:6907045
KEGG
G
Gk
glycerol kinase
IEA
X
72,416,872
72,493,296
RGD:6907045
KEGG
G
Gk2
glycerol kinase 2
IEA
14
13,547,917
13,549,769
RGD:6907045
KEGG
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IEA
2
193,128,736
193,143,106
RGD:6907045
KEGG
G
Ilk
integrin-linked kinase
IEA
1
163,481,299
163,487,550
RGD:6907045
KEGG
G
Lpl
lipoprotein lipase
IEA
16
22,533,105
22,556,905
RGD:6907045
KEGG
G
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
IEA
8
91,839,845
91,955,917
RGD:6907045
KEGG
G
Mmp1
matrix metallopeptidase 1 (interstitial collagenase)
IEA
8
4,333,773
4,354,284
RGD:6907045
KEGG
G
Nr1h3
nuclear receptor subfamily 1, group H, member 3
IEA
3
75,542,211
75,550,793
RGD:6907045
KEGG
G
Olr1
oxidized low density lipoprotein (lectin-like) receptor 1
IEA
4
166,747,228
166,769,340
RGD:6907045
KEGG
G
Pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
IEA
3
164,012,410
164,018,359
RGD:6907045
KEGG
G
Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
IEA
15
33,671,834
33,680,613
RGD:6907045
KEGG
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
IEA
10
13,329,708
13,394,080
RGD:6907045
KEGG
G
Pltp
phospholipid transfer protein
IEA
3
155,871,842
155,889,959
RGD:6907045
KEGG
G
Ppara
peroxisome proliferator activated receptor alpha
IEA
7
123,729,774
123,807,090
RGD:6907045
KEGG
G
Ppard
peroxisome proliferator-activated receptor delta
IEA
20
6,479,108
6,544,255
RGD:6907045
KEGG
G
Pparg
peroxisome proliferator-activated receptor gamma
IEA
4
151,492,220
151,617,331
RGD:6907045
KEGG
G
RGD1565355
similar to fatty acid translocase/CD36
IEA
4
13,576,484
13,604,065
RGD:6907045
KEGG
G
Rxra
retinoid X receptor alpha
IEA
3
6,605,782
6,689,224
RGD:6907045
KEGG
G
Rxrb
retinoid X receptor beta
IEA
20
4,954,336
4,960,880
RGD:6907045
KEGG
G
Rxrg
retinoid X receptor gamma
IEA
13
83,256,823
83,298,724
RGD:6907045
KEGG
G
Scd
stearoyl-CoA desaturase (delta-9-desaturase)
IEA
1
249,358,105
249,371,164
RGD:6907045
KEGG
G
Scd1
stearoyl-Coenzyme A desaturase 1
IEA
1
249,458,860
249,471,460
RGD:6907045
KEGG
G
Scd4
stearoyl-coenzyme A desaturase 4
IEA
1
249,392,727
249,404,075
RGD:6907045
KEGG
G
Scp2
sterol carrier protein 2
IEA
5
129,152,836
129,230,401
RGD:6907045
KEGG
G
Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
IEA
16
18,769,909
18,786,988
RGD:6907045
KEGG
G
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
IEA
3
114,072,570
114,114,269
RGD:6907045
KEGG
G
Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
IEA
3
8,791,504
8,802,884
RGD:6907045
KEGG
G
Slc27a5
solute carrier family 27 (fatty acid transporter), member 5
IEA
1
72,924,630
72,935,223
RGD:6907045
KEGG
G
Slc27a6
solute carrier family 27 (fatty acid transporter), member 6
IEA
18
54,351,476
54,412,298
RGD:6907045
KEGG
G
Sorbs1
sorbin and SH3 domain containing 1
IEA
1
245,419,532
245,527,846
RGD:6907045
KEGG
G
Ubc
ubiquitin C
IEA
12
32,333,211
32,337,944
RGD:6907045
KEGG
G
Ucp1
uncoupling protein 1 (mitochondrial, proton carrier)
IEA
19
26,527,548
26,535,621
RGD:6907045
KEGG
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest