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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:facilitative sugar transporter mediated glucose transport pathway
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Accession:PW:0000560 term browser browse the term
Definition:The GLUT family contains 14 members in mammals which can be grouped into 3 classes based on sequence similarities. The members of group I (best characterized) and of group III transporters facilitate glucose transport.
Synonyms:related_synonym: GLUT mediated glucose transport pathway


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facilitative sugar transporter mediated glucose transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc2a1 solute carrier family 2 member 1 ISO
IDA		 RGD PMID:15449578 PMID:2211693 PMID:15466941 RGD:1626159, RGD:2303167, RGD:1625539 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO RGD PMID:15449578 RGD:1626159 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 ISO
IDA		 RGD PMID:15449578 PMID:15320870 PMID:15466941 RGD:1626159, RGD:1642813, RGD:1625539 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO RGD PMID:15449578 PMID:15466941 RGD:1626159, RGD:1625539 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
altered insulin responsive facilitative sugar transporter mediated glucose transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:21979934 RGD:7248543 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 ISO RGD PMID:19470471 RGD:7248544 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
insulin responsive facilitative sugar transporter mediated glucose transport pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr2 actin related protein 2 IMP RGD PMID:20739464 RGD:10054052 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Actr3 actin related protein 3 IMP RGD PMID:20739464 RGD:10054052 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IMP
ISO		 PID
RGD		 PMID:11311245 PID:200196, RGD:2306432 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO
IMP		 PID
RGD		 PMID:17629673 PMID:18570632 PMID:11311245 PID:200196, RGD:2302395, RGD:2302397, RGD:2306432 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A ISO RGD PMID:20739464 RGD:10054052 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B ISO RGD PMID:20739464 RGD:10054052 NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:20739464 RGD:10054052 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 ISO RGD PMID:20739464 RGD:10054052 NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 ISO RGD PMID:20739464 RGD:10054052 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785 		JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 ISO RGD PMID:20739464 RGD:10054052 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410 		JBrowse link
G Asip agouti signaling protein ISO PID PID:200196 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171 		JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 ISO RGD PMID:24613967 RGD:10053654 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134 		JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200196 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200196 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200196 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Cbl Cbl proto-oncogene ISO RGD PMID:24613967 RGD:10053654 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:20739464 RGD:10054052 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO RGD PMID:24613967 RGD:10053654 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Dennd1c DENN domain containing 1C ISO RGD PMID:24598362 RGD:10053653 NCBI chr 9:1,904,040...1,916,329
Ensembl chr 9:1,904,045...1,916,187 		JBrowse link
G Dennd4a DENN domain containing 4A ISO RGD PMID:24598362 RGD:10053653 NCBI chr 8:65,322,920...65,436,331
Ensembl chr 8:65,322,941...65,436,330 		JBrowse link
G Dennd4b DENN domain containing 4B ISO RGD PMID:24598362 RGD:10053653 NCBI chr 2:175,720,473...175,736,425
Ensembl chr 2:175,709,610...175,736,426 		JBrowse link
G Dennd4c DENN domain containing 4C ISO RGD PMID:24598362 RGD:10053653 NCBI chr 5:101,272,298...101,369,529
Ensembl chr 5:101,272,005...101,368,118 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO PID PID:200196 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gys1 glycogen synthase 1 ISO PID PID:200196 NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292 		JBrowse link
G Ins2 insulin 2 ISO PID PID:200196 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insr insulin receptor ISO PID PID:200196 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Kif3a kinesin family member 3a ISO RGD PMID:24613967 RGD:10053654 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Kif5b kinesin family member 5B ISO RGD PMID:24613967 RGD:10053654 NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508 		JBrowse link
G Limk1 LIM domain kinase 1 IMP RGD PMID:20739464 RGD:10054052 NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606 		JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase ISO
IMP		 PID
RGD		 PMID:17717074 PMID:16967782 PID:200196, RGD:2302393, RGD:2306436 NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544 		JBrowse link
G Myo1c myosin 1C ISO RGD PMID:24613967 RGD:10053654 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myo5a myosin VA ISO RGD PMID:18570632 PMID:24613967 RGD:2302397, RGD:10053654 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Myo5b myosin Vb ISO RGD PMID:24613967 RGD:10053654 NCBI chr18:68,038,759...68,341,568
Ensembl chr18:68,038,759...68,338,745 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Plekhg4 pleckstrin homology and RhoGEF domain containing G4 ISO RGD PMID:24613967 RGD:10053654 NCBI chr19:33,251,788...33,266,490
Ensembl chr19:33,249,706...33,266,357 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma ISO PID PID:200196 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553 		JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A ISO PID PID:200196 NCBI chr 4:42,937,353...42,980,195
Ensembl chr 4:42,939,599...42,980,638 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688 		JBrowse link
G Prkci protein kinase C, iota ISO PID PID:200196 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352 		JBrowse link
G Prkcz protein kinase C, zeta ISO PID PID:200196 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Rab10 RAB10, member RAS oncogene family ISO RGD PMID:17717074 PMID:24598362 PMID:18570632 PMID:17629673 RGD:2302393, RGD:10053653, RGD:2302397, RGD:2302395 NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family ISO RGD PMID:17629673 PMID:18570632 RGD:2302395, RGD:2302397 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525 		JBrowse link
G Rab13 RAB13, member RAS oncogene family TAS RGD PMID:24598362 RGD:10053653 NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036 		JBrowse link
G Rab14 RAB14, member RAS oncogene family ISO
IMP		 RGD PMID:17717074 PMID:18701652 PMID:18570632 PMID:17629673 RGD:2302393, RGD:2306295, RGD:2302397, RGD:2302395 NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172 		JBrowse link
G Rab2a RAB2A, member RAS oncogene family ISO RGD PMID:17717074 PMID:18570632 PMID:17629673 RGD:2302393, RGD:2302397, RGD:2302395 NCBI chr 5:21,676,017...21,740,035
Ensembl chr 5:21,676,129...21,739,899 		JBrowse link
G Rab3ip RAB3A interacting protein ISO RGD PMID:24598362 RGD:10053653 NCBI chr 7:52,531,461...52,575,295
Ensembl chr 7:52,532,401...52,561,043 		JBrowse link
G Rab4a RAB4A, member RAS oncogene family ISO
IMP		 RGD PMID:17629673 PMID:8013658 PMID:18570632 RGD:2302395, RGD:2306268, RGD:2302397 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family ISO RGD PMID:17629673 RGD:2302395 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family ISO
IMP		 RGD PMID:17717074 PMID:18701652 PMID:18570632 PMID:17629673 RGD:2302393, RGD:2306295, RGD:2302397, RGD:2302395 NCBI chr16:17,654,027...17,675,385
Ensembl chr16:17,654,034...17,675,678 		JBrowse link
G Rab8b RAB8B, member RAS oncogene family ISO RGD PMID:18570632 RGD:2302397 NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rhoq ras homolog family member Q ISO PID
RGD		 PMID:24613967 PID:200196, RGD:10053654 NCBI chr 6:7,613,632...7,652,047 JBrowse link
G Sfn stratifin ISO PID PID:200196 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO
IMP
IDA		 PID
RGD		 PMID:17717074 PMID:8013658 PMID:2211693 PMID:18570632 PMID:17629673 PID:200196, RGD:2302393, RGD:2306268, RGD:2303167, RGD:2302397, RGD:2302395 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Snap23 synaptosome associated protein 23 ISO RGD PMID:17717074 PMID:18570632 RGD:2302393, RGD:2302397 NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Ssh1 slingshot protein phosphatase 1 IMP RGD PMID:20739464 RGD:10054052 NCBI chr12:42,621,127...42,683,262
Ensembl chr12:42,621,135...42,683,274 		JBrowse link
G Stx4 syntaxin 4 ISO PID
RGD		 PMID:17717074 PMID:18570632 PID:200196, RGD:2302393, RGD:2302397 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Stxbp3 syntaxin binding protein 3 ISO RGD PMID:17717074 PMID:18570632 RGD:2302393, RGD:2302397 NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671 		JBrowse link
G Stxbp4 syntaxin binding protein 4 ISO PID
RGD		 PMID:17629673 PID:200196, RGD:2302395 NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663 		JBrowse link
G Tbc1d1 TBC1 domain family member 1 TAS RGD PMID:24598362 RGD:10053653 NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 ISO RGD PMID:17717074 RGD:2302393 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 ISO RGD PMID:24613967 RGD:10053654 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 ISO PID PID:200196 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO PID
RGD		 PMID:17717074 PMID:18570632 PID:200196, RGD:2302393, RGD:2302397 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta ISO PID PID:200196 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO PID PID:200196 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma ISO PID PID:200196 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta ISO PID PID:200196 NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta ISO PID PID:200196 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta ISO PID PID:200196 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      transport pathway 470
        sugar transport pathway 79
          glucose transport pathway 79
            facilitative sugar transporter mediated glucose transport pathway 77
              altered facilitative sugar transporter mediated glucose transport pathway + 2
              insulin responsive facilitative sugar transporter mediated glucose transport pathway + 74
paths to the root