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Term:endothelin signaling pathway
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Accession:PW:0000506 term browser browse the term
Definition:Endothelins represent a family of three vasoconstrictor peptides that play a role in several intracellular signaling pathways and have been associated with hypertension, heart failure and myocardial infarction.
Synonyms:related_synonym: PID:200005

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endothelin signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adcy1 adenylate cyclase 1 (brain) GBrowse link ISO 14 87,812,256 87,923,402 RGD:6484113 PID
G Adcy2 adenylate cyclase 2 (brain) GBrowse link ISO 17 4,543,466 5,040,433 RGD:6484113 PID
G Adcy3 adenylate cyclase 3 GBrowse link ISO 6 27,118,325 27,202,275 RGD:6484113 PID
G Adcy4 adenylate cyclase 4 GBrowse link ISO 15 33,930,531 33,946,352 RGD:6484113 PID
G Adcy5 adenylate cyclase 5 GBrowse link ISO 11 67,290,968 67,437,468 RGD:6484113 PID
G Adcy6 adenylate cyclase 6 GBrowse link ISO 7 137,339,933 137,360,020 RGD:6484113 PID
G Adcy7 adenylate cyclase 7 GBrowse link ISO 19 20,051,639 20,073,861 RGD:6484113 PID
G Adcy8 adenylate cyclase 8 (brain) GBrowse link ISO 7 101,957,807 102,210,346 RGD:6484113 PID
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link ISO 6 137,640,482 137,657,552 RGD:6484113 PID
G Bcar1 breast cancer anti-estrogen resistance 1 GBrowse link ISO 19 41,646,190 41,669,234 RGD:6484113 PID
G Cdc42 cell division cycle 42 (GTP binding protein) GBrowse link ISO 5 156,106,123 156,143,040 RGD:6484113 PID
G Col1a2 collagen, type I, alpha 2 GBrowse link ISO 4 29,393,645 29,428,572 RGD:6484113 PID
G Crk v-crk sarcoma virus CT10 oncogene homolog (avian) GBrowse link ISO 10 63,017,662 63,040,420 RGD:6484113 PID
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link ISO X 94,802,078 94,803,097 RGD:6484113 PID
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link ISO 15 53,647,500 53,648,429 RGD:6484113 PID
G Ece1 endothelin converting enzyme 1 GBrowse link IMP 5 156,635,656 156,735,783 RGD:1581735 RGD
G Edn1 endothelin 1 GBrowse link ISS 17 28,303,886 28,309,775 RGD:1580323 RGD
G Edn1 endothelin 1 GBrowse link ISO 17 28,303,886 28,309,775 RGD:6484113 PID
G Edn2 endothelin 2 GBrowse link ISO 5 140,742,686 140,747,580 RGD:6484113 PID
G Edn3 endothelin 3 GBrowse link ISO 3 166,491,368 166,514,051 RGD:6484113 PID
G Ednra endothelin receptor type A GBrowse link IMP 19 32,042,366 32,108,153 RGD:4892591 RGD
G Ednra endothelin receptor type A GBrowse link ISO 19 32,042,366 32,108,153 RGD:6484113 PID
G Ednrb endothelin receptor type B GBrowse link IMP 15 87,893,141 87,898,700 RGD:4892591 RGD
G Ednrb endothelin receptor type B GBrowse link ISO 15 87,893,141 87,898,700 RGD:6484113 PID
G Fos FBJ osteosarcoma oncogene GBrowse link ISO 6 109,559,135 109,562,001 RGD:6484113 PID
G Gna11 guanine nucleotide binding protein, alpha 11 GBrowse link ISO 7 9,636,748 9,662,492 RGD:6484113 PID
G Gna12 guanine nucleotide binding protein (G protein) alpha 12 GBrowse link ISO 12 14,275,708 14,354,843 RGD:6484113 PID
G Gna14 guanine nucleotide binding protein, alpha 14 GBrowse link ISO 1 219,906,120 219,983,252 RGD:6484113 PID
G Gna15 guanine nucleotide binding protein, alpha 15 GBrowse link ISO 7 9,669,956 9,689,442 RGD:6484113 PID
G Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 GBrowse link ISO 4 12,465,089 12,495,028 RGD:6484113 PID
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 GBrowse link ISO 8 112,861,952 112,882,647 RGD:6484113 PID
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GBrowse link ISO 2 203,668,275 203,706,229 RGD:6484113 PID
G Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type GBrowse link ISO 18 63,595,606 63,735,803 RGD:6484113 PID
G Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O GBrowse link ISO 19 11,472,083 11,623,600 RGD:6484113 PID
G Gnaq guanine nucleotide binding protein (G protein), q polypeptide GBrowse link ISO 1 219,520,998 219,764,401 RGD:6484113 PID
G Gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide GBrowse link ISO 20 14,148,003 14,174,136 RGD:6484113 PID
G Hras Harvey rat sarcoma virus oncogene GBrowse link ISO 1 201,385,705 201,388,987 RGD:6484113 PID
G Jak2 Janus kinase 2 GBrowse link ISO 1 232,915,995 232,974,763 RGD:6484113 PID
G Jun jun proto-oncogene GBrowse link ISO 5 115,358,166 115,361,259 RGD:6484113 PID
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link ISO 8 68,379,074 68,451,554 RGD:6484113 PID
G Map2k2 mitogen activated protein kinase kinase 2 GBrowse link ISO 7 10,074,654 10,094,003 RGD:6484113 PID
G Mapk1 mitogen activated protein kinase 1 GBrowse link ISO 11 85,968,732 86,030,387 RGD:6484113 PID
G Mapk14 mitogen activated protein kinase 14 GBrowse link ISO 20 6,939,249 7,000,378 RGD:6484113 PID
G Mapk3 mitogen activated protein kinase 3 GBrowse link ISO 1 185,935,044 185,941,245 RGD:6484113 PID
G Mapk8 mitogen-activated protein kinase 8 GBrowse link ISO 16 8,925,133 9,004,897 RGD:6484113 PID
G Mmp1 matrix metallopeptidase 1 (interstitial collagenase) GBrowse link ISO 8 4,333,773 4,354,284 RGD:6484113 PID
G Nfatc3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 GBrowse link IMP 19 35,907,800 35,982,095 RGD:1581961 RGD
G Nos2 nitric oxide synthase 2, inducible GBrowse link IEP 10 65,036,884 65,072,453 RGD:1582119 RGD
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) GBrowse link ISO 13 64,135,729 64,280,815 RGD:6484113 PID
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link ISO 3 122,797,718 123,523,675 RGD:6484113 PID
G Plcb2 phospholipase C, beta 2 GBrowse link ISO 3 105,203,524 105,223,342 RGD:6484113 PID
G Plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) GBrowse link ISO 1 209,628,425 209,643,694 RGD:6484113 PID
G Prkca protein kinase C, alpha GBrowse link ISO 10 97,367,196 97,638,910 RGD:6484113 PID
G Prkcd protein kinase C, delta GBrowse link ISO 16 5,954,218 5,975,743 RGD:6484113 PID
G Prkce protein kinase C, epsilon GBrowse link ISO 6 9,631,234 10,097,311 RGD:6484113 PID
G Prkcg protein kinase C, gamma GBrowse link ISO 1 64,145,749 64,172,712 RGD:6484113 PID
G Prkch protein kinase C, eta GBrowse link ISO 6 96,069,354 96,281,790 RGD:6484113 PID
G Prkcq protein kinase C, theta GBrowse link ISO 17 78,486,998 78,566,741 RGD:6484113 PID
G Ptk2b protein tyrosine kinase 2 beta GBrowse link ISO 15 45,589,222 45,717,866 RGD:6484113 PID
G Rac1 ras-related C3 botulinum toxin substrate 1 GBrowse link ISO 12 11,380,314 11,400,531 RGD:6484113 PID
G Raf1 v-raf-leukemia viral oncogene 1 GBrowse link ISO 4 151,752,583 151,775,609 RGD:6484113 PID
G Rhoa ras homolog family member A ISO RGD:6484113 PID
G Slc9a1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 GBrowse link ISO 5 151,680,696 151,748,460 RGD:6484113 PID
G Slc9a3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 GBrowse link ISO 1 29,930,908 29,973,686 RGD:6484113 PID
G Src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) GBrowse link ISO 3 148,157,256 148,170,524 RGD:6484113 PID
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 GBrowse link ISO 8 5,472,515 5,577,537 RGD:6484113 PID
Term paths to the root
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  Pathway Ontology 17140
    signaling pathway 7465
      hormone signaling pathway 1128
        peptide and protein hormone signaling pathway 852
          endothelin signaling pathway 66
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