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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:lipoxygenase mediated pathway of arachidonic acid metabolism
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Accession:PW:0000462 term browser browse the term
Definition:Lipoxygenase pathway is one of three major routes of arachidonic acid oxygenation


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lipoxygenase mediated pathway of arachidonic acid metabolism term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type ISS
IMP		 RGD PMID:15896353 PMID:15105833 RGD:1578308, RGD:2313858 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISS RGD PMID:12432922 RGD:1578309 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox12e arachidonate 12-lipoxygenase, epidermal ISS RGD PMID:12432922 RGD:1578309 NCBI chr10:55,034,392...55,041,857
Ensembl chr10:55,034,392...55,041,928 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase IDA RGD PMID:8117750 RGD:70288 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B ISS RGD PMID:12432923 RGD:1578310 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP
ISO		 RGD PMID:15107407 PMID:17517102 RGD:1578311, RGD:2313910 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO
IDA		 RGD PMID:17517102 PMID:18945963 PMID:2300173 RGD:2313910, RGD:2313900, RGD:69749 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO RGD PMID:17517102 RGD:2313910 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO RGD PMID:17517102 RGD:2313910 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651 		JBrowse link
leukotriene metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO
IMP		 RGD PMID:17517102 PMID:7665580 RGD:2313910, RGD:39128168 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO
IDA		 RGD PMID:18945963 PMID:2300173 RGD:2313900, RGD:69749 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Lta4h leukotriene A4 hydrolase ISO RGD PMID:17517102 RGD:2313910 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Ltc4s leukotriene C4 synthase ISO RGD PMID:17517102 RGD:2313910 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      lipid metabolic pathway 488
        fatty acid metabolic pathway 191
          arachidonic acid metabolic pathway 83
            lipoxygenase mediated pathway of arachidonic acid metabolism 9
              leukotriene metabolic pathway + 4
paths to the root