PATHWAY ONTOLOGY - ANNOTATIONS
The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml ).
Term: remethylation pathway of homocysteine metabolism - cobalamin independent, betaine dependent
Accession: PW:0000401
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Definition: The route of homocysteine remethyation to methionine that mainly occurs in the liver and requires betaine as the methyl donor.
Synonyms: related_synonym: SMP:00123
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Ahcy
adenosylhomocysteinase
ISO
SMPDB
SMP:00123
NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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Aldh7a1
aldehyde dehydrogenase 7 family, member A1
ISO
SMPDB
SMP:00123
NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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Bhmt
betaine-homocysteine S-methyltransferase
IDA ISO
SMPDB RGD
PMID:15845641 PMID:20814827 PMID:20346934
SMP:00123, RGD:1359026 , RGD:7242426 , RGD:7242428
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Chdh
choline dehydrogenase
ISO
SMPDB
SMP:00123
NCBI chr16:5,194,269...5,225,541
Ensembl chr16:5,194,269...5,225,537
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Mat2a
methionine adenosyltransferase 2A
ISO
SMPDB
SMP:00123
NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
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Mat2b
methionine adenosyltransferase 2 non-catalytic beta subunit
ISO
SMPDB
SMP:00123
NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
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Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
ISO
SMPDB
SMP:00123
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Pemt
phosphatidylethanolamine N-methyltransferase
ISO
SMPDB
SMP:00123
NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
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