ONTOLOGY REPORT - ANNOTATIONS


Term:activin signaling pathway
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Accession:PW:0000331 term browser browse the term
Definition:Activins are members of the TGF-beta superfamily of growth factors. The pathway plays important roles in embryonic development, inflammation, reproductive biology. Deregulation of activin signaling contributes to a number of pathological conditions.
Synonyms:related_synonym: ALK1 pathway;   PID:200029


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activin signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Acvr1 activin A receptor, type I GBrowse link TAS 3 40,191,727 40,260,488 RGD:1559169 RGD
G Acvr1 activin A receptor, type I GBrowse link ISO 3 40,191,727 40,260,488 RGD:6484113 PID
G Acvr1b activin A receptor, type IB GBrowse link TAS 7 139,910,157 139,958,740 RGD:1559169 RGD
G Acvr2a activin A receptor, type IIA GBrowse link TAS 3 29,779,827 29,808,881 RGD:1559169 RGD
G Acvr2b activin A receptor, type IIB GBrowse link TAS 8 124,364,330 124,395,748 RGD:1559169 RGD
G Acvrl1 activin A receptor type II-like 1 GBrowse link TAS 7 139,873,596 139,884,675 RGD:1559169 RGD
G Acvrl1 activin A receptor type II-like 1 GBrowse link ISO 7 139,873,596 139,884,675 RGD:6484113 PID
G Fkbp1a FK506 binding protein 1a GBrowse link ISO 3 141,861,237 141,880,797 RGD:6484113 PID
G Smad2 SMAD family member 2 GBrowse link TAS 18 73,180,520 73,241,707 RGD:1559169 RGD
G Smad3 SMAD family member 3 GBrowse link TAS 8 67,803,909 67,952,056 RGD:1559169 RGD

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  Pathway Ontology 17140
    signaling pathway 7465
      growth factor signaling pathway 1032
        transforming growth factor-beta superfamily mediated signaling pathway 250
          activin signaling pathway 10
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