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Term:Bone morphogenetic proteins signaling pathway
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Accession:PW:0000330 term browser browse the term
Definition:The bone morphogenetic proteins (BMP) are related to TGF-beta and activins and are members of the TGF-beta superfamily. The BMP signaling pathway plays important roles in induction and patterning of the mesoderm. BMP pathway cross-talks to other pathways such as TGF-beta, Wnt, MAPK, Notch, JAK-STAT and others.
Synonyms:related_synonym: BMP signaling pathway;   PID:200144

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Bone morphogenetic proteins signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ahsg alpha-2-HS-glycoprotein GBrowse link ISO 11 80,330,615 80,336,658 RGD:6484113 PID
G Bambi BMP and activin membrane-bound inhibitor, homolog (Xenopus laevis) GBrowse link ISO 17 62,654,385 62,658,641 RGD:6484113 PID
G Bmp2 bone morphogenetic protein 2 GBrowse link IMP 3 121,372,692 121,381,236 RGD:1580077 RGD
G Bmp2 bone morphogenetic protein 2 GBrowse link ISO 3 121,372,692 121,381,236 RGD:6484113 PID
G Bmp4 bone morphogenetic protein 4 GBrowse link ISO 15 22,283,171 22,286,757 RGD:6484113 PID
G Bmp6 bone morphogenetic protein 6 GBrowse link ISO 17 32,380,199 32,689,295 RGD:6484113 PID
G Bmp7 bone morphogenetic protein 7 GBrowse link ISO 3 163,723,429 163,799,567 RGD:6484113 PID
G Bmpr1a bone morphogenetic protein receptor, type IA GBrowse link ISO 16 10,061,943 10,105,854 RGD:6484113 PID
G Bmpr1b bone morphogenetic protein receptor, type IB GBrowse link ISO 2 239,727,569 239,767,802 RGD:6484113 PID
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) GBrowse link IMP 9 58,327,587 58,436,057 RGD:1580077 RGD
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) GBrowse link ISO 9 58,327,587 58,436,057 RGD:6484113 PID
G Cer1 cerberus 1, DAN family BMP antagonist GBrowse link ISO 5 101,756,095 101,759,451 RGD:6484113 PID
G Chrd chordin GBrowse link ISO 11 82,401,701 82,410,401 RGD:6484113 PID
G Chrdl1 chordin-like 1 GBrowse link ISO X 35,143,324 35,246,363 RGD:6484113 PID
G Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 GBrowse link ISO 9 73,731,542 73,736,764 RGD:6484113 PID
G Fst follistatin GBrowse link ISO 2 46,542,246 46,550,678 RGD:6484113 PID
G Grem1 gremlin 1 GBrowse link ISO 3 99,597,201 99,608,935 RGD:6484113 PID
G Gsk3b glycogen synthase kinase 3 beta GBrowse link ISO 11 64,284,731 64,428,698 RGD:6484113 PID
G Hfe2 hemochromatosis type 2 (juvenile) GBrowse link ISO 2 191,329,644 191,333,525 RGD:6484113 PID
G Map3k7 mitogen activated protein kinase kinase kinase 7 GBrowse link ISO 5 48,252,637 48,308,820 RGD:6484113 PID
G Mapk1 mitogen activated protein kinase 1 GBrowse link ISO 11 85,968,732 86,030,387 RGD:6484113 PID
G Nog noggin GBrowse link ISO 10 77,689,244 77,690,871 RGD:6484113 PID
G Nup214 nucleoporin 214 GBrowse link ISO 3 11,079,165 11,165,173 RGD:6484113 PID
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A GBrowse link ISO 6 95,162,067 95,198,936 RGD:6484113 PID
G Ppp1ca protein phosphatase 1, catalytic subunit, alpha isozyme GBrowse link ISO 1 206,774,719 206,778,336 RGD:6484113 PID
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A GBrowse link ISO 1 95,994,023 95,997,080 RGD:6484113 PID
G Rgma RGM domain family, member A GBrowse link ISO 1 128,547,399 128,591,304 RGD:6484113 PID
G Smad1 SMAD family member 1 GBrowse link IMP 19 30,348,886 30,409,345 RGD:1580077 RGD
G Smad1 SMAD family member 1 GBrowse link ISO 19 30,348,886 30,409,345 RGD:6484113 PID
G Smad4 SMAD family member 4 GBrowse link ISO 18 70,432,705 70,461,541 RGD:6484113 PID
G Smad5 SMAD family member 5 GBrowse link IMP 17 13,814,164 13,824,358 RGD:1580077 RGD
G Smad5 SMAD family member 5 GBrowse link ISO 17 13,814,164 13,824,358 RGD:6484113 PID
G Smad6 SMAD family member 6 GBrowse link ISO 8 68,144,395 68,214,652 RGD:6484113 PID
G Smad7 SMAD family member 7 GBrowse link ISO 18 72,294,803 72,323,354 RGD:6484113 PID
G Smad9 SMAD family member 9 GBrowse link IMP 2 144,014,436 144,030,672 RGD:1580077 RGD
G Smad9 SMAD family member 9 GBrowse link ISO 2 144,014,436 144,030,672 RGD:6484113 PID
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 GBrowse link ISO 12 9,950,304 10,042,391 RGD:6484113 PID
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 GBrowse link ISO 10 96,170,590 96,269,365 RGD:6484113 PID
G Sostdc1 sclerostin domain containing 1 GBrowse link ISO 6 55,066,277 55,070,451 RGD:6484113 PID
G Stambp Stam binding protein GBrowse link ISS 4 117,766,905 117,791,399 RGD:1549422 RGD
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 GBrowse link ISO 7 118,368,997 118,402,928 RGD:6484113 PID
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 GBrowse link ISO 1 2,568,536 2,617,742 RGD:6484113 PID
G Xiap X-linked inhibitor of apoptosis GBrowse link ISO X 3,011,520 3,047,798 RGD:6484113 PID
G Zfyve16 zinc finger, FYVE domain containing 16 GBrowse link ISO 2 22,725,949 22,769,174 RGD:6484113 PID
Term paths to the root
Path 1
Term Annotations click to browse term
  Pathway Ontology 17140
    signaling pathway 7465
      signaling pathway pertinent to development 696
        Bone morphogenetic proteins signaling pathway 44
          altered bone morphogenetic protein signaling pathway 0
Path 2
Term Annotations click to browse term
  Pathway Ontology 17140
    signaling pathway 7465
      growth factor signaling pathway 1032
        transforming growth factor-beta superfamily mediated signaling pathway 250
          Bone morphogenetic proteins signaling pathway 44
            altered bone morphogenetic protein signaling pathway 0
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