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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:polyamine metabolic pathway
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Accession:PW:0000214 term browser browse the term
Definition:Polyamines play important roles in cell growth, proliferation and survival. They can be derived from diet as well as via cellular- and intestinal flora-mediated biosynthesis.
Synonyms:related_synonym: Metabolism of polyamines;   polyamine metabolic process

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polyamine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
RGD PMID:10430362 PMID:13678416 RGD:1578320, RGD:7244193 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Azin1 antizyme inhibitor 1 ISO RGD PMID:21849468 RGD:7244195 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 ISO RGD PMID:21849468 RGD:7244195 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 ISO RGD PMID:21849468 RGD:7244195 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 ISO RGD PMID:21849468 RGD:7244195 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA
ISO
RGD PMID:10430362 PMID:13678416 RGD:1578320, RGD:7244193 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Paox polyamine oxidase IDA
ISO
RGD PMID:15541750 PMID:13678416 RGD:7244190, RGD:7244193 NCBI chr 1:194,919,655...194,928,498
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IDA
ISO
TAS
RGD PMID:15541750 PMID:13678416 PMID:13678416 RGD:7244190, RGD:7244193, RGD:7244193 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Smox spermine oxidase IDA
ISO
RGD PMID:15541750 PMID:13678416 RGD:7244190, RGD:7244193 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Sms spermine synthase ISO RGD PMID:13678416 RGD:7244193 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
G Srm spermidine synthase ISO RGD PMID:13678416 RGD:7244193 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
putrescine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA RGD PMID:10430362 RGD:1578320 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
spermidine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA
IMP
ISO
SMPDB
RGD
PMID:10430362 PMID:10712236 PMID:1415709 SMP:00445, RGD:1578320, RGD:7242911, RGD:7242912 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Mat2a methionine adenosyltransferase 2A ISO SMPDB SMP:00445 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit ISO SMPDB SMP:00445 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA
IMP
ISO
SMPDB
RGD
PMID:10430362 PMID:1415709 PMID:2292587 SMP:00445, RGD:1578320, RGD:7242912, RGD:7242932 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IMP RGD PMID:2292587 RGD:7242932 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sms spermine synthase ISO SMPDB SMP:00445 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
G Srm spermidine synthase ISO
IDA
IMP
SMPDB
RGD
PMID:23073625 PMID:16931179 PMID:2292587 SMP:00445, RGD:7242425, RGD:7242920, RGD:7242932 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
spermine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA
ISO
IMP
SMPDB
RGD
PMID:10430362 PMID:1415709 PMID:10712236 SMP:00445, RGD:1578320, RGD:7242912, RGD:7242911 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Mat2a methionine adenosyltransferase 2A ISO SMPDB SMP:00445 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit ISO SMPDB SMP:00445 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777
JBrowse link
G Odc1 ornithine decarboxylase 1 IDA
ISO
IMP
SMPDB
RGD
PMID:10430362 PMID:2292587 PMID:1415709 SMP:00445, RGD:1578320, RGD:7242932, RGD:7242912 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 IMP RGD PMID:2292587 RGD:7242932 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sms spermine synthase ISO
IMP
SMPDB
RGD
PMID:23073625 PMID:2292587 SMP:00445, RGD:7242425, RGD:7242932 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
G Srm spermidine synthase ISO SMPDB SMP:00445 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      biogenic amines and polyamines metabolic pathway 28
        polyamine metabolic pathway 13
          putrescine metabolic pathway 2
          spermidine metabolic pathway 7
          spermine metabolic pathway 7
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3871
      homeostasis pathway 1773
        organic chemical homeostasis pathway 438
          S-adenosylmethionine homeostasis pathway 289
            polyamine metabolic pathway 13
              putrescine metabolic pathway 2
              spermidine metabolic pathway 7
              spermine metabolic pathway 7
paths to the root