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Term:Jak-Stat signaling pathway
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Accession:PW:0000209 term browser browse the term
Definition:The Jak-Stat pathway is a main intracellular cascade initiated primarily in response to cytokine and also other ligand signaling. Four Janus kinases (Jak) and seven signal transducers and activators of transcription (Stat) families of proteins mediate the action of almost 40 cytokine receptors, including the receptor for leptin. Combinations between four Jak(s) and seven Stat(s) shape the outcome of ligand triggered signaling through the various receptors.
Synonyms:related_synonym: KEGG:04630
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Jak-Stat signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link IEA 6 137,640,482 137,657,552 RGD:6907045 KEGG
G Akt2 v-akt murine thymoma viral oncogene homolog 2 GBrowse link IEA 1 82,686,233 82,726,544 RGD:6907045 KEGG
G Akt3 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) GBrowse link IEA 13 92,802,390 93,110,704 RGD:6907045 KEGG
G Bcl2l1 Bcl2-like 1 GBrowse link IEA 3 143,129,087 143,180,199 RGD:6907045 KEGG
G Cbl Cbl proto-oncogene, E3 ubiquitin protein ligase GBrowse link IEA 8 47,135,357 47,211,889 RGD:6907045 KEGG
G Cblb Cbl proto-oncogene, E3 ubiquitin protein ligase B GBrowse link IEA 11 49,690,402 49,856,762 RGD:6907045 KEGG
G Cblc Cbl proto-oncogene, E3 ubiquitin protein ligase C GBrowse link IEA 1 79,091,412 79,108,189 RGD:6907045 KEGG
G Ccnd1 cyclin D1 GBrowse link IEA 1 205,357,235 205,366,757 RGD:6907045 KEGG
G Ccnd2 cyclin D2 GBrowse link IEA 4 163,523,817 163,546,501 RGD:6907045 KEGG
G Ccnd3 cyclin D3 IEA RGD:6907045 KEGG
G Cish cytokine inducible SH2-containing protein GBrowse link IEA 8 112,541,034 112,545,982 RGD:6907045 KEGG
G Clcf1 cardiotrophin-like cytokine factor 1 GBrowse link IEA 1 206,802,745 206,806,332 RGD:6907045 KEGG
G Cntf ciliary neurotrophic factor GBrowse link IEA 1 215,842,668 215,844,691 RGD:6907045 KEGG
G Cntfr ciliary neurotrophic factor receptor IEA RGD:6907045 KEGG
G Crebbp CREB binding protein GBrowse link IEA 10 11,598,680 11,724,122 RGD:6907045 KEGG
G Crlf2 cytokine receptor-like factor 2 IEA RGD:6907045 KEGG
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link IEA 10 39,665,850 39,667,831 RGD:6907045 KEGG
G Csf2ra granulocyte-macrophage colony stimulating receptor alpha IEA RGD:6907045 KEGG
G Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) GBrowse link IEA 7 116,227,239 116,271,993 RGD:6907045 KEGG
G Csf3 colony stimulating factor 3 (granulocyte) GBrowse link IEA 10 87,473,990 87,476,365 RGD:6907045 KEGG
G Csf3r colony stimulating factor 3 receptor (granulocyte) GBrowse link IEA 5 145,374,596 145,394,045 RGD:6907045 KEGG
G Ctf1 cardiotrophin 1 GBrowse link IEA 1 187,001,445 187,006,655 RGD:6907045 KEGG
G Ep300 E1A binding protein p300 GBrowse link IEA 7 119,938,507 120,008,886 RGD:6907045 KEGG
G Epo erythropoietin GBrowse link IEA 12 19,551,768 19,555,208 RGD:6907045 KEGG
G Epor erythropoietin receptor GBrowse link IEA 8 21,061,310 21,065,886 RGD:6907045 KEGG
G Gh1 growth hormone 1 GBrowse link IEA 10 95,692,240 95,694,117 RGD:6907045 KEGG
G Ghr growth hormone receptor GBrowse link IEA 2 52,496,517 52,658,066 RGD:6907045 KEGG
G Grb2 growth factor receptor bound protein 2 GBrowse link IEA 10 105,722,014 105,818,649 RGD:6907045 KEGG
G Ifna1 interferon, alpha 1 IEA RGD:6907045 KEGG
G Ifna11 interferon alpha family, gene 11 GBrowse link IEA 5 108,150,128 108,150,703 RGD:6907045 KEGG
G Ifna1l1 interferon-alpha 1-like 1 GBrowse link IEA 5 108,011,739 108,012,317 RGD:6907045 KEGG
G Ifna2 interferon alpha family, gene 2 GBrowse link IEA 5 108,117,536 108,118,114 RGD:6907045 KEGG
G Ifna4 interferon, alpha 4 GBrowse link IEA 5 107,886,554 107,887,123 RGD:6907045 KEGG
G Ifnar1 interferon (alpha, beta and omega) receptor 1 GBrowse link IEA 11 31,454,789 31,478,449 RGD:6907045 KEGG
G Ifnb1 interferon beta 1, fibroblast GBrowse link IEA 5 107,837,628 107,838,182 RGD:6907045 KEGG
G Ifng interferon gamma GBrowse link IEA 7 57,621,756 57,625,792 RGD:6907045 KEGG
G Ifngr1 interferon gamma receptor 1 GBrowse link IEA 1 14,846,369 14,864,804 RGD:6907045 KEGG
G Ifngr2 interferon gamma receptor 2 GBrowse link IEA 11 31,508,721 31,526,993 RGD:6907045 KEGG
G Ifnk interferon kappa GBrowse link IEA 5 51,803,329 51,803,905 RGD:6907045 KEGG
G Ifnl3 interferon, lambda 3 GBrowse link IEA 1 83,617,808 83,619,340 RGD:6907045 KEGG
G Ifnlr1 interferon, lambda receptor 1 GBrowse link IEA 5 154,461,523 154,480,844 RGD:6907045 KEGG
G Il10 interleukin 10 GBrowse link IEA 13 43,953,900 43,957,766 RGD:6907045 KEGG
G Il10ra interleukin 10 receptor, alpha GBrowse link IEA 8 48,211,040 48,224,439 RGD:6907045 KEGG
G Il10rb interleukin 10 receptor, beta GBrowse link IEA 11 31,381,317 31,397,079 RGD:6907045 KEGG
G Il11 interleukin 11 GBrowse link IEA 1 67,784,584 67,795,141 RGD:6907045 KEGG
G Il11ra1 interleukin 11 receptor, alpha chain 1 GBrowse link IEA 5 59,192,698 59,199,783 RGD:6907045 KEGG
G Il12a interleukin 12A GBrowse link IEA 2 158,710,261 158,717,689 RGD:6907045 KEGG
G Il12b interleukin 12B GBrowse link IEA 10 29,558,955 29,568,331 RGD:6907045 KEGG
G Il12rb1 interleukin 12 receptor, beta 1 GBrowse link IEA 16 19,126,653 19,137,584 RGD:6907045 KEGG
G Il12rb2 interleukin 12 receptor, beta 2 GBrowse link IEA 4 96,929,755 96,995,733 RGD:6907045 KEGG
G Il13 interleukin 13 GBrowse link IEA 10 39,093,512 39,096,069 RGD:6907045 KEGG
G Il13ra1 interleukin 13 receptor, alpha 1 GBrowse link IEA X 8,758,662 8,820,545 RGD:6907045 KEGG
G Il13ra2 interleukin 13 receptor, alpha 2 GBrowse link IEA X 30,505,850 30,533,002 RGD:6907045 KEGG
G Il15 interleukin 15 GBrowse link IDA 19 27,487,268 27,498,973 RGD:5024920 RGD
G Il15 interleukin 15 GBrowse link IEA 19 27,487,268 27,498,973 RGD:6907045 KEGG
G Il15ra interleukin 15 receptor, alpha GBrowse link IMP 17 77,998,621 78,029,657 RGD:5001122 RGD
G Il19 interleukin 19 GBrowse link IEA 13 43,878,668 43,885,001 RGD:6907045 KEGG
G Il2 interleukin 2 GBrowse link IEA 2 123,655,005 123,659,709 RGD:6907045 KEGG
G Il20 interleukin 20 GBrowse link IEA 13 43,860,611 43,863,964 RGD:6907045 KEGG
G Il20ra interleukin 20 receptor, alpha GBrowse link IEA 1 14,965,655 15,009,954 RGD:6907045 KEGG
G Il20rb interleukin 20 receptor beta GBrowse link IEA 8 105,305,597 105,337,224 RGD:6907045 KEGG
G Il21 interleukin 21 GBrowse link IEA 2 123,774,331 123,781,697 RGD:6907045 KEGG
G Il21r interleukin 21 receptor GBrowse link IEA 1 184,665,737 184,693,583 RGD:6907045 KEGG
G Il22 interleukin 22 GBrowse link IEA 7 57,517,321 57,521,786 RGD:6907045 KEGG
G Il22ra1 interleukin 22 receptor, alpha 1 GBrowse link IEA 5 154,502,235 154,527,108 RGD:6907045 KEGG
G Il22ra2 interleukin 22 receptor, alpha 2 GBrowse link IEA 1 14,877,588 14,890,943 RGD:6907045 KEGG
G Il23a Interleukin 23, alpha subunit p19 GBrowse link IEA 7 1,584,112 1,586,226 RGD:6907045 KEGG
G Il23r interleukin 23 receptor GBrowse link IEA 4 97,087,580 97,768,978 RGD:6907045 KEGG
G Il24 interleukin 24 GBrowse link IEA 13 43,831,510 43,836,908 RGD:6907045 KEGG
G Il2ra interleukin 2 receptor, alpha GBrowse link IEA 17 78,050,491 78,097,802 RGD:6907045 KEGG
G Il2rb interleukin 2 receptor, beta IEA RGD:6907045 KEGG
G Il2rg interleukin 2 receptor, gamma GBrowse link IEA X 89,342,055 89,345,715 RGD:6907045 KEGG
G Il3 interleukin 3 GBrowse link IEA 10 39,684,691 39,687,041 RGD:6907045 KEGG
G Il3ra interleukin 3 receptor, alpha GBrowse link IEA 12 16,825,702 16,830,035 RGD:6907045 KEGG
G Il4 interleukin 4 GBrowse link IEA 10 39,074,582 39,080,134 RGD:6907045 KEGG
G Il4r interleukin 4 receptor GBrowse link IEA 1 184,612,903 184,637,863 RGD:6907045 KEGG
G Il5 interleukin 5 GBrowse link IEA 10 39,177,786 39,180,657 RGD:6907045 KEGG
G Il5ra interleukin 5 receptor, alpha GBrowse link IEA 4 142,067,108 142,098,051 RGD:6907045 KEGG
G Il6 interleukin 6 GBrowse link IEA 4 456,799 461,376 RGD:6907045 KEGG
G Il6r interleukin 6 receptor GBrowse link IEA 2 182,078,049 182,128,135 RGD:6907045 KEGG
G Il6st interleukin 6 signal transducer GBrowse link IEA 2 43,806,301 43,842,365 RGD:6907045 KEGG
G Il7 interleukin 7 GBrowse link IEA 2 96,356,083 96,399,796 RGD:6907045 KEGG
G Il7r interleukin 7 receptor GBrowse link IEA 2 59,103,992 59,128,004 RGD:6907045 KEGG
G Il9 interleukin 9 GBrowse link IEA 17 14,068,757 14,071,880 RGD:6907045 KEGG
G Il9r interleukin 9 receptor GBrowse link IEA 10 15,678,793 15,690,250 RGD:6907045 KEGG
G Irf1 interferon regulatory factor 1 GBrowse link IMP 10 39,220,600 39,227,602 RGD:5128774 RGD
G Irf9 interferon regulatory factor 9 GBrowse link IEA 15 33,739,755 33,744,958 RGD:6907045 KEGG
G Jak1 Janus kinase 1 GBrowse link TAS 5 121,804,586 121,905,581 RGD:1299183 RGD
G Jak1 Janus kinase 1 GBrowse link ISS 5 121,804,586 121,905,581 RGD:1625126 RGD
G Jak1 Janus kinase 1 GBrowse link IEA 5 121,804,586 121,905,581 RGD:6907045 KEGG
G Jak2 Janus kinase 2 GBrowse link IDA 1 232,915,995 232,974,763 RGD:1624963 RGD
G Jak2 Janus kinase 2 GBrowse link IEA 1 232,915,995 232,974,763 RGD:6907045 KEGG
G Jak2 Janus kinase 2 GBrowse link IDA 1 232,915,995 232,974,763 RGD:632386 RGD
G Jak2 Janus kinase 2 GBrowse link ISS 1 232,915,995 232,974,763 RGD:1625126 RGD
G Jak3 Janus kinase 3 GBrowse link ISS 16 18,878,139 18,889,441 RGD:729028 RGD
G Jak3 Janus kinase 3 GBrowse link ISS 16 18,878,139 18,889,441 RGD:1625126 RGD
G Jak3 Janus kinase 3 GBrowse link IEA 16 18,878,139 18,889,441 RGD:6907045 KEGG
G Lep leptin GBrowse link IEA 4 55,943,837 55,945,938 RGD:6907045 KEGG
G Lepr leptin receptor GBrowse link IEA 5 122,320,075 122,503,449 RGD:6907045 KEGG
G Lif leukemia inhibitory factor GBrowse link IEA 14 84,887,856 84,890,630 RGD:6907045 KEGG
G Lifr leukemia inhibitory factor receptor alpha GBrowse link IEA 2 56,426,058 56,477,198 RGD:6907045 KEGG
G Mpl myeloproliferative leukemia virus oncogene GBrowse link IEA 5 138,921,281 138,931,990 RGD:6907045 KEGG
G Myc myelocytomatosis oncogene GBrowse link IEA 7 98,953,142 98,958,060 RGD:6907045 KEGG
G Osm oncostatin M GBrowse link IEA 14 84,857,232 84,860,082 RGD:6907045 KEGG
G Osmr oncostatin M receptor GBrowse link IEA 2 56,080,700 56,121,463 RGD:6907045 KEGG
G Pias1 protein inhibitor of activated STAT, 1 GBrowse link ISS 8 67,025,248 67,123,016 RGD:2290530 RGD
G Pias1 protein inhibitor of activated STAT, 1 GBrowse link ISS 8 67,025,248 67,123,016 RGD:1357941 RGD
G Pias1 protein inhibitor of activated STAT, 1 GBrowse link IEA 8 67,025,248 67,123,016 RGD:6907045 KEGG
G Pias2 protein inhibitor of activated STAT, 2 GBrowse link ISS 18 74,078,683 74,123,668 RGD:2290530 RGD
G Pias2 protein inhibitor of activated STAT, 2 GBrowse link IEA 18 74,078,683 74,123,668 RGD:6907045 KEGG
G Pias3 protein inhibitor of activated STAT, 3 GBrowse link ISS 2 191,499,057 191,507,221 RGD:2290530 RGD
G Pias3 protein inhibitor of activated STAT, 3 GBrowse link ISS 2 191,499,057 191,507,221 RGD:1357941 RGD
G Pias3 protein inhibitor of activated STAT, 3 GBrowse link IEA 2 191,499,057 191,507,221 RGD:6907045 KEGG
G Pias4 protein inhibitor of activated STAT, 4 GBrowse link ISS 7 10,030,125 10,043,650 RGD:2290530 RGD
G Pias4 protein inhibitor of activated STAT, 4 GBrowse link ISS 7 10,030,125 10,043,650 RGD:1357941 RGD
G Pias4 protein inhibitor of activated STAT, 4 GBrowse link IEA 7 10,030,125 10,043,650 RGD:6907045 KEGG
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha GBrowse link IEA 2 118,640,277 118,672,440 RGD:6907045 KEGG
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta GBrowse link IEA 8 103,886,682 103,957,112 RGD:6907045 KEGG
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta GBrowse link IEA 5 166,735,274 166,761,189 RGD:6907045 KEGG
G Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GBrowse link IEA 2 32,602,673 32,675,350 RGD:6907045 KEGG
G Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) GBrowse link IEA 16 19,171,101 19,179,650 RGD:6907045 KEGG
G Pik3r3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) GBrowse link IEA 5 136,497,494 136,566,473 RGD:6907045 KEGG
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 GBrowse link IEA 10 55,227,872 55,248,301 RGD:6907045 KEGG
G Pim1 pim-1 oncogene GBrowse link IEA 20 7,817,403 7,821,800 RGD:6907045 KEGG
G Prl prolactin GBrowse link IEA 17 44,699,101 44,709,162 RGD:6907045 KEGG
G Prlr prolactin receptor GBrowse link IEA 2 59,507,966 59,701,221 RGD:6907045 KEGG
G Ptk2b protein tyrosine kinase 2 beta GBrowse link IMP 15 45,589,222 45,717,866 RGD:633057 RGD
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link ISS 3 159,070,473 159,116,792 RGD:2290530 RGD
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link ISS 12 36,501,886 36,558,055 RGD:2290530 RGD
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link IEA 12 36,501,886 36,558,055 RGD:6907045 KEGG
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 GBrowse link ISS 18 64,205,920 64,271,288 RGD:2290530 RGD
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link ISS 4 160,843,699 160,868,856 RGD:2290530 RGD
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link IEA 4 160,843,699 160,868,856 RGD:6907045 KEGG
G RGD1559932 similar to interferon alpha 8/6 precursor; IFNa8/6 (B6) GBrowse link IEA 5 108,328,742 108,329,296 RGD:6907045 KEGG
G RGD1565911 similar to interferon alpha 8/6 precursor; IFNa8/6 (B6) GBrowse link IEA 5 108,271,859 108,272,413 RGD:6907045 KEGG
G Socs1 suppressor of cytokine signaling 1 GBrowse link ISS 10 4,819,971 4,820,609 RGD:1357935 RGD
G Socs1 suppressor of cytokine signaling 1 GBrowse link IEA 10 4,819,971 4,820,609 RGD:6907045 KEGG
G Socs2 suppressor of cytokine signaling 2 GBrowse link ISS 7 32,605,714 32,608,323 RGD:1357935 RGD
G Socs2 suppressor of cytokine signaling 2 GBrowse link IEA 7 32,605,714 32,608,323 RGD:6907045 KEGG
G Socs3 suppressor of cytokine signaling 3 GBrowse link ISS 10 107,958,468 107,959,330 RGD:1357935 RGD
G Socs3 suppressor of cytokine signaling 3 GBrowse link IEA 10 107,958,468 107,959,330 RGD:6907045 KEGG
G Socs4 suppressor of cytokine signaling 4 GBrowse link ISS 15 23,229,083 23,243,568 RGD:1357941 RGD
G Socs4 suppressor of cytokine signaling 4 GBrowse link IEA 15 23,229,083 23,243,568 RGD:6907045 KEGG
G Socs5 suppressor of cytokine signaling 5 GBrowse link ISS 6 10,552,177 10,582,783 RGD:1357941 RGD
G Socs5 suppressor of cytokine signaling 5 GBrowse link IEA 6 10,552,177 10,582,783 RGD:6907045 KEGG
G Socs6 suppressor of cytokine signaling 6 GBrowse link ISS 18 85,722,868 85,725,214 RGD:1357941 RGD
G Socs7 suppressor of cytokine signaling 7 GBrowse link ISS 10 86,090,339 86,134,313 RGD:1357941 RGD
G Socs7 suppressor of cytokine signaling 7 GBrowse link IEA 10 86,090,339 86,134,313 RGD:6907045 KEGG
G Sos1 Son of sevenless homolog 1 (Drosophila) GBrowse link IEA 6 3,308,778 3,390,661 RGD:6907045 KEGG
G Sos2 son of sevenless homolog 2 (Drosophila) GBrowse link IEA 6 91,609,463 91,722,481 RGD:6907045 KEGG
G Spred1 sprouty-related, EVH1 domain containing 1 GBrowse link IEA 3 103,184,312 103,246,353 RGD:6907045 KEGG
G Spred2 sprouty-related, EVH1 domain containing 2 GBrowse link IEA 14 100,775,869 100,797,717 RGD:6907045 KEGG
G Spred3 sprouty-related, EVH1 domain containing 3 GBrowse link IEA 1 84,295,411 84,303,809 RGD:6907045 KEGG
G Spry2 sprouty homolog 2 (Drosophila) GBrowse link IEA 15 90,009,109 90,011,940 RGD:6907045 KEGG
G Spry3 sprouty homolog 3 (Drosophila) GBrowse link IEA 12 17,343,080 17,344,990 RGD:6907045 KEGG
G Spry4 sprouty homolog 4 (Drosophila) GBrowse link IEA 18 31,532,680 31,547,586 RGD:6907045 KEGG
G Stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 GBrowse link IEA 17 88,276,082 88,321,955 RGD:6907045 KEGG
G Stam2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 GBrowse link IEA 3 34,213,013 34,259,375 RGD:6907045 KEGG
G Stat1 signal transducer and activator of transcription 1 GBrowse link IDA 9 46,455,635 46,497,560 RGD:1299060 RGD
G Stat1 signal transducer and activator of transcription 1 GBrowse link ISS 9 46,455,635 46,497,560 RGD:1625126 RGD
G Stat1 signal transducer and activator of transcription 1 GBrowse link IEA 9 46,455,635 46,497,560 RGD:6907045 KEGG
G Stat2 signal transducer and activator of transcription 2 GBrowse link ISS 7 1,564,385 1,580,652 RGD:1357935 RGD
G Stat2 signal transducer and activator of transcription 2 GBrowse link ISS 7 1,564,385 1,580,652 RGD:1625126 RGD
G Stat2 signal transducer and activator of transcription 2 GBrowse link IEA 7 1,564,385 1,580,652 RGD:6907045 KEGG
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link TAS 10 89,821,078 89,872,970 RGD:1299183 RGD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link ISS 10 89,821,078 89,872,970 RGD:1625126 RGD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link IEA 10 89,821,078 89,872,970 RGD:6907045 KEGG
G Stat4 signal transducer and activator of transcription 4 GBrowse link ISS 9 46,510,251 46,650,076 RGD:1357935 RGD
G Stat4 signal transducer and activator of transcription 4 GBrowse link ISS 9 46,510,251 46,650,076 RGD:1625126 RGD
G Stat4 signal transducer and activator of transcription 4 GBrowse link IEA 9 46,510,251 46,650,076 RGD:6907045 KEGG
G Stat5a signal transducer and activator of transcription 5A GBrowse link IDA 10 89,795,404 89,819,732 RGD:1624963 RGD
G Stat5a signal transducer and activator of transcription 5A GBrowse link ISS 10 89,795,404 89,819,732 RGD:1357935 RGD
G Stat5a signal transducer and activator of transcription 5A GBrowse link ISS 10 89,795,404 89,819,732 RGD:1625126 RGD
G Stat5a signal transducer and activator of transcription 5A GBrowse link IEA 10 89,795,404 89,819,732 RGD:6907045 KEGG
G Stat5b signal transducer and activator of transcription 5B GBrowse link IDA 10 89,716,624 89,743,134 RGD:1624963 RGD
G Stat5b signal transducer and activator of transcription 5B GBrowse link IDA 10 89,716,624 89,743,134 RGD:628356 RGD
G Stat5b signal transducer and activator of transcription 5B GBrowse link ISS 10 89,716,624 89,743,134 RGD:1625126 RGD
G Stat5b signal transducer and activator of transcription 5B GBrowse link IEA 10 89,716,624 89,743,134 RGD:6907045 KEGG
G Stat6 signal transducer and activator of transcription 6, interleukin-4 induced GBrowse link ISS 7 67,623,534 67,642,283 RGD:1357935 RGD
G Stat6 signal transducer and activator of transcription 6, interleukin-4 induced GBrowse link ISS 7 67,623,534 67,642,283 RGD:1625126 RGD
G Stat6 signal transducer and activator of transcription 6, interleukin-4 induced GBrowse link IEA 7 67,623,534 67,642,283 RGD:6907045 KEGG
G Tpo thyroid peroxidase GBrowse link IEA 6 47,954,848 48,025,740 RGD:6907045 KEGG
G Tslp thymic stromal lymphopoietin GBrowse link IEA 18 25,268,082 25,274,214 RGD:6907045 KEGG
G Tyk2 tyrosine kinase 2 GBrowse link ISS 8 20,096,969 20,149,004 RGD:1357935 RGD
G Tyk2 tyrosine kinase 2 GBrowse link ISS 8 20,096,969 20,149,004 RGD:1625126 RGD
altered Jak-Stat signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Jak2 Janus kinase 2 GBrowse link ISS 1 232,915,995 232,974,763 RGD:1357939 RGD
G Jak3 Janus kinase 3 GBrowse link ISS 16 18,878,139 18,889,441 RGD:1357939 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  Pathway Ontology 17154
    signaling pathway 7601
      Jak-Stat signaling pathway 187
        altered Jak-Stat signaling pathway 2
Path 2
Term Annotations click to browse term
  Pathway Ontology 17154
    signaling pathway 7601
      kinase mediated signaling pathway 846
        tyrosine-specific protein kinase mediated signaling pathway 187
          Jak-Stat signaling pathway 187
            altered Jak-Stat signaling pathway 2
paths to the root

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