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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:long term depression
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Accession:PW:0000061 term browser browse the term
Definition:Long term depression is a weakening of a synapse that lasts hours to days. It results from either strong synaptic stimulation (as in the cerebellum) or to weak synaptic stimulation (as in the hippocampus), and engages several cascades.
Comment:Adapted from Wikipedia at OneLook
Synonyms:related_synonym: LTD;   long-term synaptic depression


show annotations for term's descendants           Sort by:
long term depression term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase IEA KEGG rno:04730 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA KEGG rno:04730 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Crh corticotropin releasing hormone IEA KEGG rno:04730 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEA KEGG rno:04730 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Gna11 G protein subunit alpha 11 IEA KEGG rno:04730 NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gna12 G protein subunit alpha 12 IEA KEGG rno:04730 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Gna13 G protein subunit alpha 13 IEA KEGG rno:04730 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774 		JBrowse link
G Gnai1 G protein subunit alpha i1 IEA KEGG rno:04730 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 IEA KEGG rno:04730 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IEA KEGG rno:04730 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnao1 G protein subunit alpha o1 IEA KEGG rno:04730 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnaq G protein subunit alpha q IEA KEGG rno:04730 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gnas GNAS complex locus IEA KEGG rno:04730 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnaz G protein subunit alpha z IEA KEGG rno:04730 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEA KEGG rno:04730 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IEA KEGG rno:04730 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 IEA KEGG rno:04730 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 IEA KEGG rno:04730 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IMP RGD PMID:17655746 PMID:16904707 RGD:1642204, RGD:1642207 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 IEA KEGG rno:04730 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 IEA KEGG rno:04730 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:17329210 RGD:1641844 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 IEA KEGG rno:04730 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 IEA KEGG rno:04730 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 IEA KEGG rno:04730 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 IEA KEGG rno:04730 NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441 		JBrowse link
G Hras HRas proto-oncogene, GTPase IEA KEGG rno:04730 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Igf1 insulin-like growth factor 1 IEA KEGG rno:04730 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEA KEGG rno:04730 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEA KEGG rno:04730 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 IEA KEGG rno:04730 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 IEA KEGG rno:04730 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA KEGG rno:04730 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IEA KEGG rno:04730 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEA KEGG rno:04730 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 IEA KEGG rno:04730 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEA KEGG rno:04730 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEA KEGG rno:04730 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nos1 nitric oxide synthase 1 IEA KEGG rno:04730 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nras NRAS proto-oncogene, GTPase IEA KEGG rno:04730 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:04730 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:04730 NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:04730 NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743 		JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:04730 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:04730 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:04730 NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377 		JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:04730 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:04730 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:04730 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IEA KEGG rno:04730 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA KEGG rno:04730 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853 		JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:04730 NCBI chr 3:107,132,540...107,198,609
Ensembl chr 3:107,132,541...107,198,233 		JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:04730 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689 		JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:04730 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:04730 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Plcb1 phospholipase C beta 1 IEA KEGG rno:04730 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Plcb2 phospholipase C, beta 2 IEA KEGG rno:04730 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302 		JBrowse link
G Plcb3 phospholipase C beta 3 IEA KEGG rno:04730 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228 		JBrowse link
G Plcb4 phospholipase C, beta 4 IEA KEGG rno:04730 NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IEA KEGG rno:04730 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta IEA KEGG rno:04730 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha IEA KEGG rno:04730 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta IEA KEGG rno:04730 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Prkca protein kinase C, alpha IEA KEGG rno:04730 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcb protein kinase C, beta IEA KEGG rno:04730 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04730 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IEA KEGG rno:04730 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 IEA KEGG rno:04730 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEA KEGG rno:04730 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      signaling pathway pertinent to the brain and nervous system 465
        neuron-to-neuron signaling pathways 282
          neuron-to-neuron signaling pathway via the chemical synapse 280
            excitatory synaptic transmission pathway 189
              long term depression 69
paths to the root