ONTOLOGY REPORT - ANNOTATIONS

Term:pyruvate metabolic pathway
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Accession:PW:0000043 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of pyruvate - a salt, ester, or anionic form of pyruvic acid. Pyruvate, which is the end-product of glycolysis can be converted to lactate under anaerobic conditions, can be further oxidized via the Krebs or citrate cycle or can be converted back to glucose via gluconeogenesis.
Synonyms:related_synonym: KEGG:00620
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pyruvate metabolic pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Acaca acetyl-CoA carboxylase alpha GBrowse link IEA 10 72,483,772 72,677,134 RGD:6907045 KEGG
G Acacb acetyl-CoA carboxylase beta GBrowse link IEA 12 43,388,679 43,492,993 RGD:6907045 KEGG
G Acat1 acetyl-CoA acetyltransferase 1 GBrowse link IEA 8 57,044,478 57,072,970 RGD:6907045 KEGG
G Acat2 acetyl-CoA acetyltransferase 2 GBrowse link IEA 1 41,922,020 41,940,074 RGD:6907045 KEGG
G Acot12 acyl-CoA thioesterase 12 GBrowse link IEA 2 21,984,849 22,035,224 RGD:6907045 KEGG
G Acss1 acyl-CoA synthetase short-chain family member 1 GBrowse link IEA 3 141,259,016 141,308,871 RGD:6907045 KEGG
G Acss2 acyl-CoA synthetase short-chain family member 2 GBrowse link IEA 3 146,013,995 146,057,119 RGD:6907045 KEGG
G Acyp1 acylphosphatase 1, erythrocyte (common) type GBrowse link IEA 6 109,320,444 109,327,303 RGD:6907045 KEGG
G Acyp2 acylphosphatase 2, muscle type GBrowse link IEA 14 111,507,725 111,512,680 RGD:6907045 KEGG
G Akr1b1 aldo-keto reductase family 1, member B1 (aldose reductase) GBrowse link IEA 4 61,645,438 61,659,530 RGD:6907045 KEGG
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 GBrowse link IEA 1 223,731,675 223,773,285 RGD:6907045 KEGG
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 GBrowse link IEA 1 223,822,536 223,875,238 RGD:6907045 KEGG
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 GBrowse link IEA 5 62,311,268 62,316,276 RGD:6907045 KEGG
G Aldh2 aldehyde dehydrogenase 2 family (mitochondrial) GBrowse link IEA 12 36,081,778 36,116,445 RGD:6907045 KEGG
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 GBrowse link IEA 10 47,400,518 47,421,064 RGD:6907045 KEGG
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 GBrowse link IEA 18 52,300,899 52,333,149 RGD:6907045 KEGG
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 GBrowse link IEA 13 83,017,312 83,034,047 RGD:6907045 KEGG
G Dlat dihydrolipoamide S-acetyltransferase GBrowse link ISS 8 53,989,491 54,014,779 RGD:2307427 RGD
G Dlat dihydrolipoamide S-acetyltransferase GBrowse link IEA 8 53,989,491 54,014,779 RGD:6907045 KEGG
G Dld dihydrolipoamide dehydrogenase GBrowse link ISS 6 49,185,188 49,205,894 RGD:2307427 RGD
G Dld dihydrolipoamide dehydrogenase GBrowse link IEA 6 49,185,188 49,205,894 RGD:6907045 KEGG
G Glo1 glyoxalase 1 GBrowse link IEA 20 8,900,984 8,919,001 RGD:6907045 KEGG
G Hagh hydroxyacyl glutathione hydrolase GBrowse link IEA 10 14,106,047 14,117,459 RGD:6907045 KEGG
G Ldha lactate dehydrogenase A GBrowse link IEA 1 97,403,077 97,412,547 RGD:6907045 KEGG
G Ldhal6b lactate dehydrogenase A-like 6B GBrowse link IEA 1 40,399,144 40,400,567 RGD:6907045 KEGG
G Ldhb lactate dehydrogenase B GBrowse link IEA 4 180,061,567 180,079,473 RGD:6907045 KEGG
G Ldhc lactate dehydrogenase C GBrowse link IEA 1 97,418,622 97,435,275 RGD:6907045 KEGG
G Ldhd lactate dehydrogenase D GBrowse link IEA 19 41,532,048 41,553,996 RGD:6907045 KEGG
G Mdh1 malate dehydrogenase 1, NAD (soluble) GBrowse link IEA 14 102,259,130 102,273,788 RGD:6907045 KEGG
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) GBrowse link IEA 12 22,021,302 22,034,257 RGD:6907045 KEGG
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic GBrowse link IEA 8 91,839,845 91,955,917 RGD:6907045 KEGG
G Me2 malic enzyme 2, NAD(+)-dependent, mitochondrial GBrowse link IEA 18 70,545,530 70,590,828 RGD:6907045 KEGG
G Me3 malic enzyme 3, NADP(+)-dependent, mitochondrial GBrowse link IEA 1 146,220,504 146,422,659 RGD:6907045 KEGG
G Pc pyruvate carboxylase GBrowse link IEA 1 207,112,853 207,212,737 RGD:6907045 KEGG
G Pc pyruvate carboxylase GBrowse link IDA 1 207,112,853 207,212,737 RGD:1601554 RGD
G Pck1 phosphoenolpyruvate carboxykinase 1 (soluble) GBrowse link IEA 3 164,012,410 164,018,359 RGD:6907045 KEGG
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) GBrowse link IEA 15 33,671,834 33,680,613 RGD:6907045 KEGG
G Pdha1 pyruvate dehydrogenase (lipoamide) alpha 1 GBrowse link ISS X 55,899,491 55,913,319 RGD:2307427 RGD
G Pdha1 pyruvate dehydrogenase (lipoamide) alpha 1 GBrowse link IEA X 55,899,491 55,913,319 RGD:6907045 KEGG
G Pdha2 pyruvate dehydrogenase (lipoamide) alpha 2 GBrowse link ISS 2 238,983,103 238,984,651 RGD:2307427 RGD
G Pdha2 pyruvate dehydrogenase (lipoamide) alpha 2 GBrowse link IEA 2 238,983,103 238,984,651 RGD:6907045 KEGG
G Pdhb pyruvate dehydrogenase (lipoamide) beta GBrowse link ISS 15 18,737,449 18,743,391 RGD:2307427 RGD
G Pdhb pyruvate dehydrogenase (lipoamide) beta GBrowse link IEA 15 18,737,449 18,743,391 RGD:6907045 KEGG
G Pdhx pyruvate dehydrogenase complex, component X GBrowse link ISS 3 88,240,250 88,270,914 RGD:2307427 RGD
G Pdk1 pyruvate dehydrogenase kinase, isozyme 1 GBrowse link ISS 3 54,292,076 54,319,242 RGD:2307427 RGD
G Pdk1 pyruvate dehydrogenase kinase, isozyme 1 GBrowse link ISS 3 54,292,076 54,319,242 RGD:2307428 RGD
G Pdk2 pyruvate dehydrogenase kinase, isozyme 2 GBrowse link ISS 10 83,710,448 83,724,973 RGD:2307427 RGD
G Pdk2 pyruvate dehydrogenase kinase, isozyme 2 GBrowse link ISS 10 83,710,448 83,724,973 RGD:2307428 RGD
G Pdk3 pyruvate dehydrogenase kinase, isozyme 3 GBrowse link ISS X 81,104,667 81,171,536 RGD:2307427 RGD
G Pdk3 pyruvate dehydrogenase kinase, isozyme 3 GBrowse link ISS X 81,104,667 81,171,536 RGD:2307428 RGD
G Pdk4 pyruvate dehydrogenase kinase, isozyme 4 GBrowse link ISS 4 30,235,296 30,245,298 RGD:2307427 RGD
G Pdk4 pyruvate dehydrogenase kinase, isozyme 4 GBrowse link ISS 4 30,235,296 30,245,298 RGD:2307428 RGD
G Pdp1 pyruvate dehyrogenase phosphatase catalytic subunit 1 GBrowse link ISS 5 26,234,414 26,240,301 RGD:2307428 RGD
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 GBrowse link ISS 19 307,961 312,004 RGD:2307428 RGD
G Pklr pyruvate kinase, liver and RBC GBrowse link IEA 2 181,214,853 181,223,505 RGD:6907045 KEGG
G Pklr pyruvate kinase, liver and RBC GBrowse link IDA 2 181,214,853 181,223,505 RGD:2302790 RGD
G Pkm pyruvate kinase, muscle GBrowse link IDA 8 63,486,492 63,508,016 RGD:2302790 RGD
G RGD1562690 similar to L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M) GBrowse link IEA 8 31,685,666 31,686,664 RGD:6907045 KEGG
Term paths to the root
Path 1
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  Pathway Ontology 17154
    classic metabolic pathway 3652
      carbohydrate metabolic pathway 833
        pyruvate metabolic pathway 58
Path 2
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  Pathway Ontology 17154
    regulatory pathway 5692
      homeostasis pathway 2069
        glucose homeostasis pathway 694
          glucose utilization pathway 196
            glucose oxidation pathway 161
              pyruvate metabolic pathway 58
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