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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:pyrimidine metabolic pathway
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Accession:PW:0000032 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of pyrimidines. Cytosine, thymine and uracil - the nucleobases found in nucleic acids, are pyrimidine derivatives.
Synonyms:related_synonym: pyrimidine nucleobase metabolic process


show annotations for term's descendants           Sort by:
pyrimidine metabolic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak3 adenylate kinase 3 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cant1 calcium activated nucleotidase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109 		JBrowse link
G Cda cytidine deaminase IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 IEA KEGG rno:00240 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Ctps1 CTP synthase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctps2 CTP synthase 2 IEA KEGG rno:00240 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
G Dck deoxycytidine kinase IEA KEGG rno:00240 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Dctd dCMP deaminase IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446 		JBrowse link
G Dhfr dihydrofolate reductase IDA RGD PMID:11502523 RGD:1298877 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:7626590 SMP:00046 rno:00240, RGD:1624989 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dpys dihydropyrimidinase IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:7626590 SMP:00046 rno:00240, RGD:1624989 NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231 		JBrowse link
G Dtymk deoxythymidylate kinase IEA KEGG rno:00240 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870 		JBrowse link
G Dut deoxyuridine triphosphatase IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:3032103 SMP:00046 rno:00240, RGD:2300191 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEA KEGG rno:00240 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 IEA KEGG rno:00240 NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943 		JBrowse link
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 IEA KEGG rno:00240 NCBI chr15:44,630,878...44,658,654
Ensembl chr15:44,630,873...44,658,706 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 IEA KEGG rno:00240 NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530 		JBrowse link
G Entpd6 ectonucleoside triphosphate diphosphohydrolase 6 IEA KEGG rno:00240 NCBI chr 3:139,575,659...139,598,163
Ensembl chr 3:139,575,686...139,598,154 		JBrowse link
G Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 IEA KEGG rno:00240 NCBI chr 3:7,885,277...7,895,517
Ensembl chr 3:7,889,909...7,895,296 		JBrowse link
G Gda guanine deaminase ISO SMPDB SMP:00046 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Itpa inosine triphosphatase IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 IEA KEGG rno:00240 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 IEA KEGG rno:00240 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 IEA KEGG rno:00240 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359 		JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 IEA KEGG rno:00240 NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301 		JBrowse link
G Nme7 NME/NM23 family member 7 IEA KEGG rno:00240 NCBI chr13:76,657,303...76,786,768
Ensembl chr13:76,657,367...76,786,765 		JBrowse link
G Nt5c1a 5'-nucleotidase, cytosolic IA IEA KEGG rno:00240 NCBI chr 5:135,473,107...135,494,400
Ensembl chr 5:135,473,231...135,499,338 		JBrowse link
G Nt5c1b 5'-nucleotidase, cytosolic IB IEA KEGG rno:00240 NCBI chr 6:33,139,053...33,156,489
Ensembl chr 6:33,139,064...33,156,481 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II ISO SMPDB SMP:00046 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913 		JBrowse link
G Nt5c3a 5'-nucleotidase, cytosolic IIIA IEA KEGG rno:00240 NCBI chr 4:86,161,642...86,204,656
Ensembl chr 4:86,161,643...86,204,628 		JBrowse link
G Nt5e 5' nucleotidase, ecto IEA KEGG rno:00240 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Nt5m 5',3'-nucleotidase, mitochondrial IEA KEGG rno:00240 NCBI chr10:44,652,845...44,680,549
Ensembl chr10:44,652,975...44,679,150 		JBrowse link
G Nudt2 nudix hydrolase 2 IEA KEGG rno:00240 NCBI chr 5:56,628,265...56,643,104
Ensembl chr 5:56,628,265...56,643,104 		JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 IEA KEGG rno:00240 NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit IEA KEGG rno:00240 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit IEA KEGG rno:00240 NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit IEA KEGG rno:00240 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit IEA KEGG rno:00240 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit IEA KEGG rno:00240 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit IEA KEGG rno:00240 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit IEA KEGG rno:00240 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit IEA KEGG rno:00240 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305 		JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit IEA KEGG rno:00240 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
Ensembl chr 7:75,974,717...75,977,231 		JBrowse link
G Pole4 DNA polymerase epsilon 4, accessory subunit IEA KEGG rno:00240 NCBI chr 4:115,165,285...115,171,097
Ensembl chr 4:115,165,285...115,171,097 		JBrowse link
G Polr1a RNA polymerase I subunit A IEA KEGG rno:00240 NCBI chr 4:103,950,051...104,014,022
Ensembl chr 4:103,950,051...104,014,020 		JBrowse link
G Polr1b RNA polymerase I subunit B IEA KEGG rno:00240 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379 		JBrowse link
G Polr1c RNA polymerase I and III subunit C IEA KEGG rno:00240 NCBI chr 9:14,735,740...14,739,852
Ensembl chr 9:14,735,714...14,739,852 		JBrowse link
G Polr1e RNA polymerase I subunit E IEA KEGG rno:00240 NCBI chr 5:59,279,456...59,295,346
Ensembl chr 5:59,279,460...59,295,369 		JBrowse link
G Polr1h RNA polymerase I subunit H IEA KEGG rno:00240 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854 		JBrowse link
G Polr2a RNA polymerase II subunit A IEA KEGG rno:00240 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455 		JBrowse link
G Polr2b RNA polymerase II subunit B IEA KEGG rno:00240 NCBI chr14:30,797,228...30,834,916
Ensembl chr14:30,797,228...30,834,916 		JBrowse link
G Polr2c RNA polymerase II subunit C IEA KEGG rno:00240 NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945 		JBrowse link
G Polr2d RNA polymerase II subunit D IEA KEGG rno:00240 NCBI chr18:23,418,097...23,425,228
Ensembl chr18:23,418,097...23,425,228 		JBrowse link
G Polr2e RNA polymerase II, I and III subunit E IEA KEGG rno:00240 NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643 		JBrowse link
G Polr2f RNA polymerase II, I and III subunit F IEA KEGG rno:00240 NCBI chr 7:110,712,528...110,724,234
Ensembl chr 7:110,712,572...110,724,234 		JBrowse link
G Polr2g RNA polymerase II subunit G IEA KEGG rno:00240 NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686 		JBrowse link
G Polr2h RNA polymerase II, I and III subunit H IEA KEGG rno:00240 NCBI chr11:80,192,017...80,197,468
Ensembl chr11:80,192,032...80,197,515
Ensembl chr10:80,192,032...80,197,515 		JBrowse link
G Polr2i RNA polymerase II subunit I IEA KEGG rno:00240 NCBI chr 1:85,483,515...85,484,952
Ensembl chr 1:85,483,515...85,484,952 		JBrowse link
G Polr2j RNA polymerase II subunit J IEA KEGG rno:00240 NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594 		JBrowse link
G Polr2l RNA polymerase II, I and III subunit L IEA KEGG rno:00240 NCBI chr 1:196,570,051...196,572,060 JBrowse link
G Polr3a RNA polymerase III subunit A IEA KEGG rno:00240 NCBI chr16:49,178...88,178
Ensembl chr16:49,521...88,172 		JBrowse link
G Polr3b RNA polymerase III subunit B IEA KEGG rno:00240 NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598 		JBrowse link
G Polr3c RNA polymerase III subunit C IEA KEGG rno:00240 NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208 		JBrowse link
G Polr3d RNA polymerase III subunit D IEA KEGG rno:00240 NCBI chr15:45,511,587...45,516,256
Ensembl chr15:45,511,589...45,516,353 		JBrowse link
G Polr3e RNA polymerase III subunit E IEA KEGG rno:00240 NCBI chr 1:175,466,091...175,494,679
Ensembl chr 1:175,466,127...175,494,667 		JBrowse link
G Polr3f RNA polymerase III subunit F IEA KEGG rno:00240 NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837 		JBrowse link
G Polr3g RNA polymerase III subunit G IEA KEGG rno:00240 NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125 		JBrowse link
G Polr3gl RNA polymerase III subunit GL IEA KEGG rno:00240 NCBI chr 2:184,111,570...184,129,200
Ensembl chr 2:184,112,510...184,129,114 		JBrowse link
G Polr3h RNA polymerase III subunit H IEA KEGG rno:00240 NCBI chr 7:113,429,434...113,439,743
Ensembl chr 7:113,429,451...113,439,778 		JBrowse link
G Polr3k RNA polymerase III subunit K IEA KEGG rno:00240 NCBI chr 3:168,982,846...168,987,043
Ensembl chr 3:168,982,812...168,987,040 		JBrowse link
G Prim1 DNA primase subunit 1 IEA KEGG rno:00240 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526 		JBrowse link
G Prim2 DNA primase subunit 2 IEA KEGG rno:00240 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 IEA KEGG rno:00240 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Tk1 thymidine kinase 1 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tk2 thymidine kinase 2 IEA KEGG rno:00240 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IEA KEGG rno:00240 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Txnrd2 thioredoxin reductase 2 IEA KEGG rno:00240 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156 		JBrowse link
G Txnrd3 thioredoxin reductase 3 IEA KEGG rno:00240 NCBI chr 4:122,072,548...122,112,493
Ensembl chr 4:122,072,548...122,112,491 		JBrowse link
G Tymp thymidine phosphorylase IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
G Tyms thymidylate synthetase IEA
IDA
ISO		 KEGG
SMPDB
RGD		 PMID:9894005 SMP:00046 rno:00240, RGD:1545055 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Uck1 uridine-cytidine kinase 1 IEA KEGG rno:00240 NCBI chr 3:15,538,580...15,544,465
Ensembl chr 3:15,538,591...15,544,465 		JBrowse link
G Uck2 uridine-cytidine kinase 2 IEA KEGG rno:00240 NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 3:168,674,849...168,687,513
Ensembl chr 3:168,674,849...168,698,091 		JBrowse link
G Umps uridine monophosphate synthetase IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
G Upb1 beta-ureidopropionase 1 IEA
ISO
IDA		 KEGG
SMPDB
RGD		 PMID:7626590 SMP:00046 rno:00240, RGD:1624989 NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590 		JBrowse link
G Upp1 uridine phosphorylase 1 IEA KEGG rno:00240 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462 		JBrowse link
G Upp2 uridine phosphorylase 2 IEA
ISO		 KEGG
SMPDB		 SMP:00046 rno:00240 NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417 		JBrowse link
G Uprt uracil phosphoribosyltransferase homolog IEA KEGG rno:00240 NCBI chr  X:69,516,573...69,546,811
Ensembl chr  X:69,516,738...69,546,797 		JBrowse link
de novo pyrimidine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:15096496 RGD:5133412 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 ISO RGD PMID:12678497 RGD:5133414 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 IDA RGD PMID:192455 RGD:5133256 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Ctps1 CTP synthase 1 ISO RGD PMID:12678497 RGD:5133414 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctps2 CTP synthase 2 ISO RGD PMID:20739275 RGD:5133419 NCBI chr  X:31,645,873...31,786,733
Ensembl chr  X:31,645,873...31,786,733 		JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) ISO RGD PMID:15096496 RGD:5133412 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO RGD PMID:11768308 RGD:5134680 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO RGD PMID:11768308 RGD:5134680 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 ISO RGD PMID:11768308 RGD:5134680 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359 		JBrowse link
G Nme4 NME/NM23 nucleoside diphosphate kinase 4 ISO RGD PMID:11768308 RGD:5134680 NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 ISO RGD PMID:11768308 RGD:5134680 NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301 		JBrowse link
G Umps uridine monophosphate synthetase ISO RGD PMID:15096496 RGD:5133412 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    classic metabolic pathway 1854
      nucleotide metabolic pathway 185
        pyrimidine metabolic pathway 94
          pyrimidine biosynthetic pathway + 12
          pyrimidine degradation pathway 0
paths to the root