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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased surfactant secretion
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Accession:MP:0010993 term browser browse the term
Definition:decreased production or release from pneumocytes of surfactant, a phospholipid present in the lungs that controls surface tension in the alveoli
Synonyms:exact_synonym: decreased production of surfactant;   reduced production of surfactant;   reduced surfactant secretion
 alt_id: MP:0010991



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decreased surfactant secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:24465451 RGD:13462051 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:24465451 RGD:13462051

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5402
    respiratory system phenotype 47
      abnormal respiratory system physiology 24
        abnormal surfactant physiology 6
          abnormal surfactant secretion 6
            decreased surfactant secretion 3
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