ONTOLOGY REPORT - ANNOTATIONS


Term:absent spleen germinal center
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Accession:MP:0008474 term browser browse the term
Definition:absence of the area of the spleen secondary B follicle where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs
Comment:Germinal centers are often identified by the binding of peanut agglutinin (PNA).
Synonyms:exact_synonym: absent spleen GC;   absent spleen follicle center;   absent spleen follicle centre;   absent splenic germinal center


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Path 1
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  mammalian phenotype 6278
    hematopoietic system phenotype 94
      abnormal hematopoietic system morphology/development 93
        abnormal spleen morphology 1
          abnormal spleen white pulp morphology 0
            abnormal spleen B cell follicle morphology 0
              abnormal spleen secondary B follicle morphology 0
                abnormal spleen germinal center morphology 0
                  absent spleen germinal center 0
Path 2
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  mammalian phenotype 6278
    immune system phenotype 431
      abnormal immune system morphology 74
        abnormal immune system organ morphology 21
          abnormal spleen morphology 1
            abnormal spleen white pulp morphology 0
              abnormal spleen B cell follicle morphology 0
                abnormal spleen secondary B follicle morphology 0
                  abnormal spleen germinal center morphology 0
                    absent spleen germinal center 0
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