abnormal leukopoiesis - Ontology Report

Keyword

ONTOLOGY REPORT - ANNOTATIONS

Term:	abnormal leukopoiesis	go back to main search page
Accession:	MP:0005460	browse the term
Definition:	any anomaly in the process of generating white blood cells (leukocytes) from the pluripotent hematopoietic stem cells of the bone marrow; two significant pathways generate various types of leukocytes: myelopoiesis, in which leukocytes in the blood are derived from myeloid stem cells, and lymphopoiesis, in which leukocytes of the lymphatic system (lymphocytes) are generated from lymphoid stem cells
Synonyms:	exact_synonym:	abnormal immune cell development; abnormal leukocyte differentiation; abnormal leukocyte morphology/development; immune cell developmental abnormalities
	alt_id:	MP:0002430; MP:0002449

abnormal lymphopoiesis
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
S	WIN/RhwRrrc			TAS				RGD:2292495	RGD
abnormal mononuclear cell differentiation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
S	BN	BN		TAS				RGD:1004	RGD
abnormal T cell differentiation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
S	WKAH.LEC-Ptprk^thid/Tj			TAS	1	17,328,563	17,752,200	RGD:1302502	RGD
increased double-negative T cell number
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
Q	Neudeg2	Neurodegradation QTL 2		IAGP	5	25,602,274	45,822,846	RGD:1358788	RGD
Q	Neuinf1	Neuroinflammation QTL 1		IAGP	5	161,449,395	173,096,209	RGD:1358788	RGD
increased T cell proliferation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
Q	Ean2	Experimental allergic neuritis QTL 2		IED	4	82,700,691	96,313,512	RGD:2306769	RGD
Q	Ean4	Experimental allergic neuritis QTL 4		IED	10	87,849,516	98,392,508	RGD:2306769	RGD
Q	Ean5	Experimental allergic neuritis QTL 5		IED	10	76,043,832	98,392,296	RGD:2306769	RGD

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	6278
immune system phenotype	431
abnormal immune system morphology	74
abnormal immune system cell morphology	53
abnormal leukopoiesis	8
abnormal common lymphocyte progenitor cell morphology	0
abnormal lymphopoiesis +	7
abnormal mononuclear cell differentiation +	8
abnormal myelopoiesis +	0
Path 2
Term	Annotations
mammalian phenotype	6278
hematopoietic system phenotype	94
abnormal hematopoietic system morphology/development	93
abnormal blood cell morphology/development	74
abnormal hematopoiesis	74
abnormal leukopoiesis	8
abnormal common lymphocyte progenitor cell morphology	0
abnormal lymphopoiesis +	7
abnormal mononuclear cell differentiation +	8
abnormal myelopoiesis +	0