ONTOLOGY REPORT - ANNOTATIONS

Term:increased spleen weight
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Accession:MP:0004952 term browser browse the term
Definition:greater than average weight of the organ that functions to filter blood and to store red corpuscles and platelets
Synonyms:exact_synonym: increased splenic weight

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increased spleen weight term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adam10 a disintegrin and metallopeptidase domain 10 GBrowse link IAGP 9 70,526,808 70,628,036 RGD:5509061 MGI
G Add2 adducin 2 (beta) GBrowse link IAGP 6 86,028,078 86,069,549 RGD:5509061 MGI
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) GBrowse link IAGP 2 26,449,107 26,459,730 RGD:5509061 MGI
G Ahr aryl-hydrocarbon receptor GBrowse link IAGP 12 36,182,651 36,219,661 RGD:5509061 MGI
G Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) GBrowse link IAGP 10 77,492,776 77,506,325 RGD:5509061 MGI
G Alox15 arachidonate 15-lipoxygenase GBrowse link IAGP 11 70,157,649 70,165,533 RGD:5509061 MGI
G Ank1 ankyrin 1, erythroid GBrowse link IAGP 8 24,085,354 24,260,968 RGD:5509061 MGI
G Apoe apolipoprotein E GBrowse link IAGP 7 20,281,593 20,284,515 RGD:5509061 MGI
G Atmin ATM interactor GBrowse link IAGP 8 119,467,293 119,484,345 RGD:5509061 MGI
G Bcl11b B cell leukemia/lymphoma 11B GBrowse link IAGP 12 109,148,613 109,241,624 RGD:5509061 MGI
G Bcl2 B cell leukemia/lymphoma 2 GBrowse link IAGP 1 108,434,756 108,610,867 RGD:5509061 MGI
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) GBrowse link IAGP 2 127,951,774 127,988,283 RGD:5509061 MGI
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) GBrowse link IAGP 2 127,951,774 127,988,283 RGD:5509061 MGI
G Bco2 beta-carotene oxygenase 2 GBrowse link IAGP 9 50,341,192 50,363,243 RGD:5509061 MGI
G Braf Braf transforming gene GBrowse link IAGP 6 39,553,236 39,675,462 RGD:5509061 MGI
G C4b complement component 4B (Chido blood group) GBrowse link IAGP 17 34,865,325 34,880,842 RGD:5509061 MGI
G Capn10 calpain 10 GBrowse link IAGP 1 94,830,985 94,844,525 RGD:5509061 MGI
G Ccne1 cyclin E1 GBrowse link IAGP 7 38,883,003 38,892,509 RGD:5509061 MGI
G Cd19 CD19 antigen GBrowse link IAGP 7 133,551,962 133,558,384 RGD:5509061 MGI
G Cd19 CD19 antigen GBrowse link IAGP 7 133,551,962 133,558,384 RGD:5509061 MGI
G Cd19 CD19 antigen GBrowse link IAGP 7 133,551,962 133,558,384 RGD:5509061 MGI
G Cd19 CD19 antigen GBrowse link IAGP 7 133,551,962 133,558,384 RGD:5509061 MGI
G Cd79a CD79A antigen (immunoglobulin-associated alpha) GBrowse link IAGP 7 25,682,530 25,687,216 RGD:5509061 MGI
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) GBrowse link IAGP 17 29,227,931 29,237,667 RGD:5509061 MGI
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link IAGP 6 134,870,419 134,875,543 RGD:5509061 MGI
G Col1a1 collagen, type I, alpha 1 GBrowse link IAGP 11 94,797,584 94,813,181 RGD:5509061 MGI
G Coro1a coronin, actin binding protein 1A GBrowse link IAGP 7 133,843,288 133,848,268 RGD:5509061 MGI
G Csf1r colony stimulating factor 1 receptor GBrowse link IAGP 18 61,265,226 61,290,793 RGD:5509061 MGI
G Ctsg cathepsin G GBrowse link IAGP 14 56,718,718 56,721,411 RGD:5509061 MGI
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link IAGP 1 74,200,568 74,207,820 RGD:5509061 MGI
G Cycs cytochrome c, somatic GBrowse link IAGP 6 50,512,562 50,516,473 RGD:5509061 MGI
G Dbnl drebrin-like GBrowse link IAGP 11 5,688,486 5,700,983 RGD:5509061 MGI
G Dcc deleted in colorectal carcinoma GBrowse link IAGP 18 71,413,286 72,510,723 RGD:5509061 MGI
G Dck deoxycytidine kinase GBrowse link IAGP 5 89,194,038 89,212,302 RGD:5509061 MGI
G Diap1 diaphanous homolog 1 (Drosophila) GBrowse link IAGP 18 38,004,478 38,095,065 RGD:5509061 MGI
G Dido1 death inducer-obliterator 1 GBrowse link IAGP 2 180,392,669 180,444,704 RGD:5509061 MGI
G Dusp6 dual specificity phosphatase 6 GBrowse link IAGP 10 98,725,865 98,730,123 RGD:5509061 MGI
G E2f2 E2F transcription factor 2 GBrowse link IAGP 4 135,728,309 135,751,972 RGD:5509061 MGI
G Egr1 early growth response 1 GBrowse link IAGP 18 35,020,861 35,024,610 RGD:5509061 MGI
G Ep300 E1A binding protein p300 GBrowse link IAGP 15 81,416,644 81,482,507 RGD:5509061 MGI
G Epb4.2 erythrocyte protein band 4.2 GBrowse link IAGP 2 120,843,953 120,862,491 RGD:5509061 MGI
G Epgn epithelial mitogen GBrowse link IAGP 5 91,456,543 91,464,238 RGD:5509061 MGI
G Epo erythropoietin GBrowse link IAGP 5 137,924,248 137,927,044 RGD:5509061 MGI
G Fas Fas (TNF receptor superfamily member 6) GBrowse link IAGP 19 34,365,149 34,402,260 RGD:5509061 MGI
G Fas Fas (TNF receptor superfamily member 6) GBrowse link IAGP 19 34,365,149 34,402,260 RGD:5509061 MGI
G Fas Fas (TNF receptor superfamily member 6) GBrowse link IAGP 19 34,365,149 34,402,260 RGD:5509061 MGI
G Fas Fas (TNF receptor superfamily member 6) GBrowse link IAGP 19 34,365,149 34,402,260 RGD:5509061 MGI
G Fas Fas (TNF receptor superfamily member 6) GBrowse link IAGP 19 34,365,149 34,402,260 RGD:5509061 MGI
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide GBrowse link IAGP 1 173,159,703 173,164,480 RGD:5509061 MGI
G Fcgr2b Fc receptor, IgG, low affinity IIb GBrowse link IAGP 1 172,890,689 172,906,202 RGD:5509061 MGI
G Fcgr2b Fc receptor, IgG, low affinity IIb GBrowse link IAGP 1 172,890,689 172,906,202 RGD:5509061 MGI
G Fcgr3 Fc receptor, IgG, low affinity III GBrowse link IAGP 1 172,981,300 172,989,534 RGD:5509061 MGI
G Fech ferrochelatase GBrowse link IAGP 18 64,616,204 64,648,720 RGD:5509061 MGI
G Foxp3 forkhead box P3 GBrowse link IAGP X 7,156,819 7,172,360 RGD:5509061 MGI
G Foxp3 forkhead box P3 GBrowse link IAGP X 7,156,819 7,172,360 RGD:5509061 MGI
G Gata1 GATA binding protein 1 GBrowse link IAGP X 7,536,386 7,544,941 RGD:5509061 MGI
G Gba glucosidase, beta, acid GBrowse link IAGP 3 89,006,850 89,012,603 RGD:5509061 MGI
G Gba glucosidase, beta, acid GBrowse link IAGP 3 89,006,850 89,012,603 RGD:5509061 MGI
G Gpi1 glucose phosphate isomerase 1 GBrowse link IAGP 7 34,986,346 35,015,324 RGD:5509061 MGI
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano GBrowse link IAGP 6 113,017,422 113,027,238 RGD:5509061 MGI
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano GBrowse link IAGP 6 113,017,422 113,027,238 RGD:5509061 MGI
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano GBrowse link IAGP 6 113,017,422 113,027,238 RGD:5509061 MGI
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano GBrowse link IAGP 6 113,017,422 113,027,238 RGD:5509061 MGI
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano GBrowse link IAGP 6 113,017,422 113,027,238 RGD:5509061 MGI
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano GBrowse link IAGP 6 113,017,422 113,027,238 RGD:5509061 MGI
G Hbb-b1 hemoglobin, beta adult major chain GBrowse link IAGP 7 110,961,042 110,962,437 RGD:5509061 MGI
G Hbb-b2 hemoglobin, beta adult minor chain IAGP RGD:5509061 MGI
G Hcst hematopoietic cell signal transducer GBrowse link IAGP 7 31,202,731 31,204,873 RGD:5509061 MGI
G Hip1 huntingtin interacting protein 1 GBrowse link IAGP 5 135,882,388 136,020,992 RGD:5509061 MGI
G Hk1 hexokinase 1 GBrowse link IAGP 10 61,731,603 61,842,656 RGD:5509061 MGI
G Hsh2d hematopoietic SH2 domain containing GBrowse link IAGP 8 74,713,567 74,724,857 RGD:5509061 MGI
G Igf1 insulin-like growth factor 1 GBrowse link IAGP 10 87,321,801 87,399,792 RGD:5509061 MGI
G Il10rb interleukin 10 receptor, beta GBrowse link IAGP 16 91,406,480 91,426,079 RGD:5509061 MGI
G Il4 interleukin 4 GBrowse link IAGP 11 53,425,962 53,432,167 RGD:5509061 MGI
G Inpp5d inositol polyphosphate-5-phosphatase D GBrowse link IAGP 1 89,516,887 89,617,083 RGD:5509061 MGI
G Itgad integrin, alpha D GBrowse link IAGP 7 135,317,460 135,349,018 RGD:5509061 MGI
G Jak2 Janus kinase 2 GBrowse link IAGP 19 29,326,318 29,387,570 RGD:5509061 MGI
G Kcnn4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 GBrowse link IAGP 7 25,155,282 25,170,231 RGD:5509061 MGI
G Kiss1r KISS1 receptor GBrowse link IAGP 10 79,379,716 79,385,018 RGD:5509061 MGI
G Klf1 Kruppel-like factor 1 (erythroid) GBrowse link IAGP 8 87,425,827 87,429,194 RGD:5509061 MGI
G Ldha lactate dehydrogenase A GBrowse link IAGP 7 54,101,174 54,110,997 RGD:5509061 MGI
G Lgmn legumain GBrowse link IAGP 12 103,632,308 103,677,907 RGD:5509061 MGI
G Lipa lysosomal acid lipase A GBrowse link IAGP 19 34,566,806 34,601,964 RGD:5509061 MGI
G Lipa lysosomal acid lipase A GBrowse link IAGP 19 34,566,806 34,601,964 RGD:5509061 MGI
G Lta lymphotoxin A GBrowse link IAGP 17 35,340,110 35,342,296 RGD:5509061 MGI
G Lta lymphotoxin A GBrowse link IAGP 17 35,340,110 35,342,296 RGD:5509061 MGI
G Lyz2 lysozyme 2 GBrowse link IAGP 10 116,714,597 116,719,328 RGD:5509061 MGI
G Mark2 MAP/microtubule affinity-regulating kinase 2 GBrowse link IAGP 19 7,349,886 7,416,334 RGD:5509061 MGI
G Mc2r melanocortin 2 receptor GBrowse link IAGP 18 68,566,561 68,588,913 RGD:5509061 MGI
G Mfge8 milk fat globule-EGF factor 8 protein GBrowse link IAGP 7 86,278,654 86,293,946 RGD:5509061 MGI
G Mir144 microRNA 144 GBrowse link IAGP 11 77,886,507 77,886,572 RGD:5509061 MGI
G Mir146 microRNA 146 GBrowse link IAGP 11 43,187,899 43,187,963 RGD:5509061 MGI
G Mir146 microRNA 146 GBrowse link IAGP 11 43,187,899 43,187,963 RGD:5509061 MGI
G Mir451 microRNA 451 GBrowse link IAGP 11 77,886,672 77,886,743 RGD:5509061 MGI
G Mt1 metallothionein 1 GBrowse link IAGP 8 96,702,989 96,704,227 RGD:5509061 MGI
G Mt2 metallothionein 2 GBrowse link IAGP 8 96,696,518 96,697,467 RGD:5509061 MGI
G Myc myelocytomatosis oncogene GBrowse link IAGP 15 61,816,896 61,821,916 RGD:5509061 MGI
G Ndfip1 Nedd4 family interacting protein 1 GBrowse link IAGP 18 38,578,629 38,624,060 RGD:5509061 MGI
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link IAGP 2 75,513,576 75,542,698 RGD:5509061 MGI
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link IAGP 2 75,513,576 75,542,698 RGD:5509061 MGI
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 GBrowse link IAGP 19 46,379,227 46,386,580 RGD:5509061 MGI
G Npm1 nucleophosmin 1 GBrowse link IAGP 11 33,052,511 33,063,056 RGD:5509061 MGI
G Npm1 nucleophosmin 1 GBrowse link IAGP 11 33,052,511 33,063,056 RGD:5509061 MGI
G Oca2 oculocutaneous albinism II GBrowse link IAGP 7 63,495,141 63,791,887 RGD:5509061 MGI
G Oca2 oculocutaneous albinism II GBrowse link IAGP 7 63,495,141 63,791,887 RGD:5509061 MGI
G Pappa2 pappalysin 2 GBrowse link IAGP 1 160,641,862 160,887,569 RGD:5509061 MGI
G Pfkm phosphofructokinase, muscle GBrowse link IAGP 15 97,923,020 97,962,878 RGD:5509061 MGI
G Pgm3 phosphoglucomutase 3 GBrowse link IAGP 9 86,446,083 86,465,449 RGD:5509061 MGI
G Pla2g15 phospholipase A2, group XV GBrowse link IAGP 8 108,674,299 108,688,615 RGD:5509061 MGI
G Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A IAGP RGD:5509061 MGI
G Prdx1 peroxiredoxin 1 GBrowse link IAGP 4 116,358,204 116,372,605 RGD:5509061 MGI
G Prdx2 peroxiredoxin 2 GBrowse link IAGP 8 87,493,547 87,498,212 RGD:5509061 MGI
G Prep prolyl endopeptidase GBrowse link IAGP 10 44,787,020 44,878,801 RGD:5509061 MGI
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link IAGP 15 5,093,861 5,131,899 RGD:5509061 MGI
G Prkcq protein kinase C, theta GBrowse link IAGP 2 11,094,009 11,222,853 RGD:5509061 MGI
G Pten phosphatase and tensin homolog GBrowse link IAGP 19 32,832,067 32,900,650 RGD:5509061 MGI
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link IAGP 5 121,580,542 121,641,406 RGD:5509061 MGI
G Rc3h1 RING CCCH (C3H) domains 1 GBrowse link IAGP 1 162,836,542 162,905,107 RGD:5509061 MGI
G Rc3h1 RING CCCH (C3H) domains 1 GBrowse link IAGP 1 162,836,542 162,905,107 RGD:5509061 MGI
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B GBrowse link IAGP 7 20,191,571 20,214,787 RGD:5509061 MGI
G Rictor RPTOR independent companion of MTOR, complex 2 GBrowse link IAGP 15 6,658,381 6,750,401 RGD:5509061 MGI
G Runx1 runt related transcription factor 1 GBrowse link IAGP 16 92,601,711 92,826,311 RGD:5509061 MGI
G Runx1 runt related transcription factor 1 GBrowse link IAGP 16 92,601,711 92,826,311 RGD:5509061 MGI
G Runx1 runt related transcription factor 1 GBrowse link IAGP 16 92,601,711 92,826,311 RGD:5509061 MGI
G Sele selectin, endothelial cell GBrowse link IAGP 1 165,978,365 165,987,808 RGD:5509061 MGI
G Selp selectin, platelet GBrowse link IAGP 1 166,045,509 166,079,876 RGD:5509061 MGI
G Sfpi1 SFFV proviral integration 1 GBrowse link IAGP 2 90,936,954 90,955,913 RGD:5509061 MGI
G Sfpi1 SFFV proviral integration 1 GBrowse link IAGP 2 90,936,954 90,955,913 RGD:5509061 MGI
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 GBrowse link IAGP 15 100,218,329 100,253,486 RGD:5509061 MGI
G Slc20a1 solute carrier family 20, member 1 GBrowse link IAGP 2 129,024,509 129,037,351 RGD:5509061 MGI
G Slc4a4 solute carrier family 4 (anion exchanger), member 4 GBrowse link IAGP 5 89,316,285 89,668,681 RGD:5509061 MGI
G Slc7a7 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 GBrowse link IAGP 14 54,989,128 55,036,536 RGD:5509061 MGI
G Spic Spi-C transcription factor (Spi-1/PU.1 related) GBrowse link IAGP 10 88,138,014 88,145,768 RGD:5509061 MGI
G Spta1 spectrin alpha, erythrocytic 1 GBrowse link IAGP 1 176,102,907 176,178,580 RGD:5509061 MGI
G Tal1 T cell acute lymphocytic leukemia 1 GBrowse link IAGP 4 114,732,132 114,744,360 RGD:5509061 MGI
G Tbk1 TANK-binding kinase 1 GBrowse link IAGP 10 120,983,511 121,023,850 RGD:5509061 MGI
G Tet2 tet methylcytosine dioxygenase 2 GBrowse link IAGP 3 133,126,641 133,207,354 RGD:5509061 MGI
G Thbd thrombomodulin GBrowse link IAGP 2 148,230,207 148,233,924 RGD:5509061 MGI
G Tlr4 toll-like receptor 4 GBrowse link IAGP 4 66,488,845 66,503,831 RGD:5509061 MGI
G Tlr8 toll-like receptor 8 GBrowse link IAGP X 163,680,664 163,701,720 RGD:5509061 MGI
G Tmprss6 transmembrane serine protease 6 GBrowse link IAGP 15 78,270,097 78,299,064 RGD:5509061 MGI
G Tnf tumor necrosis factor GBrowse link IAGP 17 35,336,335 35,338,941 RGD:5509061 MGI
G Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b GBrowse link IAGP 11 60,954,337 60,961,144 RGD:5509061 MGI
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link IAGP 14 78,677,253 78,707,850 RGD:5509061 MGI
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link IAGP 14 78,677,253 78,707,850 RGD:5509061 MGI
G Tnip1 TNFAIP3 interacting protein 1 GBrowse link IAGP 11 54,724,289 54,776,440 RGD:5509061 MGI
G Traf3ip2 TRAF3 interacting protein 2 GBrowse link IAGP 10 39,332,740 39,375,113 RGD:5509061 MGI
G Traf3ip2 TRAF3 interacting protein 2 GBrowse link IAGP 10 39,332,740 39,375,113 RGD:5509061 MGI
G Ttc7 tetratricopeptide repeat domain 7 GBrowse link IAGP 17 87,682,226 87,781,110 RGD:5509061 MGI
G Ulk1 unc-51 like kinase 1 GBrowse link IAGP 5 111,213,508 111,239,100 RGD:5509061 MGI
G Vhl von Hippel-Lindau tumor suppressor GBrowse link IAGP 6 113,574,015 113,581,627 RGD:5509061 MGI
G Zfp36 zinc finger protein 36 GBrowse link IAGP 7 29,161,803 29,164,247 RGD:5509061 MGI
G Zfpm1 zinc finger protein, multitype 1 GBrowse link IAGP 8 124,806,041 124,861,147 RGD:5509061 MGI
G Zfpm1 zinc finger protein, multitype 1 GBrowse link IAGP 8 124,806,041 124,861,147 RGD:5509061 MGI
Q Adip1_m adiposity 1 (mouse) GBrowse link IAGP 1 2,802,051 36,802,209 RGD:5509061 MGI
Q Imebt1_m imprinting effect on body traits 1 (mouse) IAGP RGD:5509061 MGI
Q Lbw2_m lupus NZB x NZW 2 (mouse) GBrowse link IAGP 4 107,439,115 141,439,213 RGD:5509061 MGI
Q Lmb1_m lupus in MRL and B6 F2 cross (mouse) GBrowse link IAGP 4 107,048,407 141,048,603 RGD:5509061 MGI
Q Mtbcq2_m multiple trait body composition QTL 2 (mouse) IAGP RGD:5509061 MGI
Q Mtgq4_m multiple trait growth QTL 4 (mouse) IAGP RGD:5509061 MGI
Q Orgwq1_m organ weight QTL 1 (mouse) GBrowse link IAGP 1 119,185,942 153,186,082 RGD:5509061 MGI
Q Orgwq2_m organ weight QTL 2 (mouse) GBrowse link IAGP 2 43,528,325 77,528,469 RGD:5509061 MGI
Q Orgwq6_m organ weight QTL 6 (mouse) GBrowse link IAGP 4 71,709,736 105,709,883 RGD:5509061 MGI
Q Orgwq7_m organ weight QTL 7 (mouse) GBrowse link IAGP 9 20,202,486 54,202,659 RGD:5509061 MGI
Q Orgwq8_m organ weight QTL 8 (mouse) GBrowse link IAGP 11 6,178 34,006,316 RGD:5509061 MGI
Q Pbwg1.9_m postnatal body weight growth 1.9 (mouse) IAGP RGD:5509061 MGI
Q Sle16_m systematic lupus erythematosus susceptibility 16 (mouse) GBrowse link IAGP 1 171,141,303 179,480,152 RGD:5509061 MGI
Q Splwt1_m spleen weight 1 (mouse) IAGP RGD:5509061 MGI
Q Spnw1_m spleen weight 1 (mouse) IAGP RGD:5509061 MGI
Q Spnw4_m spleen weight 4 (mouse) IAGP RGD:5509061 MGI
Q Spw3_m spleen weight 3 (mouse) IAGP RGD:5509061 MGI
Q Spw5_m spleen weight 5 (mouse) IAGP RGD:5509061 MGI
Q Swq6_m spleen weight QTL 6 (mouse) GBrowse link IAGP 2 138,693,152 172,693,260 RGD:5509061 MGI
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 192063
    hematopoietic system phenotype 18838
      abnormal hematopoietic system morphology/development 18083
        abnormal spleen morphology 2533
          abnormal spleen size 1205
            enlarged spleen 846
              increased spleen weight 173
Path 2
Term Annotations click to browse term
  mammalian phenotype 192063
    immune system phenotype 29677
      abnormal immune system morphology 15012
        abnormal immune system organ morphology 4888
          abnormal lymph organ size 2198
            abnormal spleen size 1205
              enlarged spleen 846
                increased spleen weight 173
paths to the root

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