abnormal cardiovascular system morphology - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	abnormal cardiovascular system morphology	go back to main search page
Accession:	MP:0002127	browse the term
Definition:	any structural anomaly of the heart or vascular tissue
Synonyms:	exact_synonym:	abnormal cardiovascular system; cardiovascular dysplasia; cardiovascular system abnormalities; cardiovascular system defects; cardiovascular system dysplasia; heart/cardiovascular system: dysmorphology
	alt_id:	MP:0000177
	xref:	MGI:2173587

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abnormal aorta morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Cardf1	Cardiac cell morphology QTL 1			QTM	13	1,265,159	46,912,163	RGD:727992	RGD
S	WKHT/N				TAS				RGD:1004	RGD
abnormal aortic weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Bp281	Blood pressure QTL 281			IED	10	77,956,239	87,272,656	RGD:1599557	RGD
Q	Bp316	Blood pressure QTL 316			IED	8	58,548,876	103,548,876	RGD:1599557	RGD
Q	Bp321	Blood pressure QTL 321			IED	16	819,369	3,080,748	RGD:1599557	RGD
Q	Cm67	Cardiac mass QTL 67			IED	2	158,146,823	182,740,242	RGD:1599557	RGD
Q	Cm68	Cardiac mass QTL 68			IED	3	27,762,470	68,832,545	RGD:1599557	RGD
Q	Cm69	Cardiac mass QTL 69			IED	10	69,555,329	71,032,765	RGD:1599557	RGD
Q	Cm7	Cardiac mass QTL 7			QTM	1	201,920,676	246,920,676	RGD:629621	RGD
Q	Cm70	Cardiac mass QTL 70			IED	18	6,934,443	12,677,409	RGD:1599557	RGD
Q	Cm8	Cardiac mass QTL 8			QTM	3	14,056,777	59,056,777	RGD:629621	RGD
Q	Cm9	Cardiac mass QTL 9			QTM	19	1	29,295,214	RGD:629621	RGD
Q	Kidm38	Kidney mass QTL 38			IED	10	87,834,315	100,429,624	RGD:1599557	RGD
abnormal blood vessel morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Flt1	FMS-related tyrosine kinase 1			IEA	12	7,858,092	8,035,966	RGD:704404	RGD
G	Gata4	GATA binding protein 4			IEA	15	42,472,793	42,519,569	RGD:704404	RGD
S	GH/Omr	Genetically Hypertensive			QTM				RGD:619605	RGD
abnormal choroid vasculature morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Cd36	CD36 molecule (thrombospondin receptor)			IAGP	4	13,471,878	13,525,620	RGD:2307226	RGD
abnormal heart development
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Gja1	gap junction protein, alpha 1			IEA	20	35,409,815	35,422,262	RGD:704404	RGD
G	Gja5	gap junction protein, alpha 5			IEA	2	191,824,118	191,843,867	RGD:704404	RGD
abnormal heart morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	GH				TAS				RGD:1004	RGD
abnormal heart size
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Cm2	Cardiac mass QTL 2			QTM	8	58,135,371	104,697,495	RGD:727992	RGD
Q	Cm3	Cardiac mass QTL 3			QTM	8	57,308,742	58,692,901	RGD:727992	RGD
Q	Cm32	Cardiac mass QTL 32			QTM	1	103,149,923	206,567,907	RGD:1302893	RGD
Q	Cm33	Cardiac mass QTL 33			QTM	10	56,930,545	97,589,703	RGD:1302893	RGD
Q	Cm34	Cardiac mass QTL 34			QTM	17	9,988,620	81,039,660	RGD:1302893	RGD
Q	Cm35	Cardiac mass QTL35			QTM	1	181,524,849	263,699,089	RGD:1302893	RGD
Q	Cm36	Cardiac mass QTL 36			QTM	1	103,149,923	206,567,907	RGD:1302893	RGD
Q	Cm4	Cardiac mass QTL 4			QTM	9	1	37,313,370	RGD:727992	RGD
Q	Cm5	Cardiac mass QTL 5			QTM	12	29,130,180	46,043,557	RGD:727992	RGD
Q	Cm6	Cardiac mass QTL 6			QTM	7	47,145,774	107,950,815	RGD:727992	RGD
abnormal heart ventricle morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Cm6	Cardiac mass QTL 6			QTM	7	47,145,774	107,950,815	RGD:727992	RGD
abnormal interventricular septum morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Foxo1	forkhead box O1			IEA	2	141,127,345	141,203,446	RGD:704404	RGD
abnormal kidney blood vessel morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Rends1	Renal damage susceptibility QTL 1			QTM	1	146,971,846	202,915,231	RGD:632218	RGD
Q	Rends2	Renal damage susceptibility QTL 2			QTM				RGD:631854	RGD
Q	Rends3	Renal damage susceptibility QTL 3			QTM	10	83,527,877	89,167,279	RGD:631854	RGD
Q	Rends4	Renal damage susceptibility QTL 4			QTM	16	1	26,804,456	RGD:631854	RGD
S	FCH				TAS				RGD:1004	RGD
abnormal retinal vasculature morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Gh1	growth hormone 1			IEA	10	95,692,240	95,694,117	RGD:704404	RGD
G	Kdr	kinase insert domain receptor			IED				RGD:1581593	RGD
abnormal tricuspid valve morphology
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Foxo1	forkhead box O1			IEA	2	141,127,345	141,203,446	RGD:704404	RGD
abnormal vascular development
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Cryba1	crystallin, beta A1			IAGP	10	63,758,929	63,765,451	RGD:2303652	RGD
altered susceptibility to atherosclerosis
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Vetf1	Vascular elastic tissue fragility QTL 1			QTM	5	1,368,223	5,112,800	RGD:619605	RGD
Q	Vetf2	Vascular elastic tissue fragility QTL 2			QTM	10	36,254,741	95,369,088	RGD:619605	RGD
artery occlusion
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Vnigr3	Vascular neointimal growth QTL 3			IED	3	132,947,812	171,063,335	RGD:2316923	RGD
S	SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco				IED				RGD:2316923	RGD
S	SHR.BN-(D3Rat159-D3Rat1)/Mco				IED	3	119,437,175	170,016,653	RGD:2316923	RGD
S	SHR.BN-(D6Rat40-D6Rat170)/Mco				IED	6	1,301,952	46,792,623	RGD:2316923	RGD
calcified artery
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Mgp	matrix Gla protein			IED	4	173,910,595	173,913,917	RGD:2293588	RGD
cardiac fibrosis
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	SHRSP-Tg(Tagln-ACE2)6918Bdr				IED				RGD:2302131	RGD
cardiac hypertrophy
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	A2m	alpha-2-macroglobulin			IED	4	158,103,711	158,153,423	RGD:1549856	RGD
G	Agtr1b	angiotensin II receptor, type 1b			TAS	2	105,503,269	105,602,591	RGD:629553	RGD
G	Agtr2	angiotensin II receptor, type 2			IAGP				RGD:1566500	RGD
G	Ccnd1	cyclin D1			IED	1	205,357,235	205,366,757	RGD:704385	RGD
G	Cdk4	cyclin-dependent kinase 4			IED				RGD:704385	RGD
G	Crebbp	CREB binding protein		Induced	IED	10	11,598,680	11,724,122	RGD:1298794	RGD
G	Ep300	E1A binding protein p300		Induced	IED	7	119,938,507	120,008,886	RGD:1298794	RGD
G	Fkbp1a	FK506 binding protein 1a			IEA	3	141,861,237	141,880,797	RGD:704404	RGD
G	Fkbp1b	FK506 binding protein 1b			IEA				RGD:704404	RGD
G	Igf1	insulin-like growth factor 1			IED	7	24,531,669	24,605,742	RGD:1580474	RGD
G	Npr2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)			IAGP	5	60,107,563	60,127,960	RGD:1601488	RGD
G	Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isozyme			IED	2	234,130,176	234,409,232	RGD:1580700	RGD
G	Ppp3cb	protein phosphatase 3, catalytic subunit, beta isozyme			IED	15	3,986,290	4,030,352	RGD:1580703	RGD
G	Rcan1	regulator of calcineurin 1			IED	11	32,386,576	32,408,850	RGD:1581475	RGD
G	S1pr1	sphingosine-1-phosphate receptor 1			IMP	2	211,851,304	211,855,511	RGD:1357201	RGD
Q	Bp105	Blood pressure QTL 105			QTM	2	116,874,922	221,284,686	RGD:619651	RGD
Q	Calcic2	Intracellular calcium level QTL 2			IED	12	29,130,180	42,387,195	RGD:1599588	RGD
Q	Cm43	Cardiac mass QTL 43			IAGP	3	6,373,454	26,674,018	RGD:1554311	RGD
Q	Cm44	Cardiac mass QTL 44			IAGP	10	67,677,924	100,865,886	RGD:1554311	RGD
Q	Cm45	Cardiac mass QTL 45			IAGP	13	25,198,204	70,198,204	RGD:1554311	RGD
Q	Cm46	Cardiac mass QTL 46			IAGP	3	6,373,454	26,674,018	RGD:1554311	RGD
Q	Cm47	Cardiac mass QTL 47			IAGP	6	59,946,874	108,503,674	RGD:1554311	RGD
Q	Cm48	Cardiac mass QTL 48			IAGP	3	6,373,454	26,674,018	RGD:1554311	RGD
S	LEW-Tg(Ren2)27				IED				RGD:2293121	RGD
S	SHR.F344-(D12Mgh5-D12Mgh6)/Snk				TAS	12	29,130,180	42,387,195	RGD:1599588	RGD
S	SHRSP/Gcrc	Spontaneously hypertensive rat, stroke prone			TAS				RGD:2301356	RGD
S	SS-Chr 12^BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi				IED				RGD:7204442	RGD
S	SS.LEW-(D10Rat141-D10Mgh1)/Ayd				TAS	19	38,295,381	38,295,550	RGD:625380	RGD
S	SS.LEW-(D16Uia2-D16Rat12)/Ayd				QTM	16	350,121	4,304,517	RGD:70460	RGD
S	SS/JrHsdMcwi				IED				RGD:727992	RGD
S	WKHT/Edh				IED				RGD:7245528	RGD
cardiac interstitial fibrosis
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	SS-Chr 12^BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi				IED				RGD:7204442	RGD
S	SS-Chr 19^SHR/Rkb			Resistance	IED				RGD:2307185	RGD
decreased angiogenesis
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	SS.BN-(D13Rat20-D13Got22)/Mcwi			Induced	IED	13 5	38,329,089 97,701,780	45,828,716 97,703,112	RGD:2289092	RGD
S	SS.BN-(D13Rat91-D13Rat179)/Mcwi			Induced	IED	13	46,911,975	60,669,696	RGD:2289092	RGD
decreased aorta elastin content
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Ael1	Aortic elastin QTL 1			IAGP	2	18,905,511	63,905,511	RGD:1334448	RGD
Q	Ael2	Aortic elastin QTL 2			IAGP				RGD:1334448	RGD
Q	Ael3	Aortic elastin QTL 3			IAGP	14	10,539,919	55,539,919	RGD:1334448	RGD
decreased heart left ventricle weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2			IAGP	7	113,043,365	113,049,779	RGD:727991	RGD
S	F344/NHsd	F344/NHsd			QTM				RGD:69706	RGD
S	SS-Chr 19^SHR/Rkb				IED				RGD:1600252	RGD
decreased heart right ventricle weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	F344/NHsd	F344/NHsd			QTM				RGD:69706	RGD
decreased heart weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Bp316	Blood pressure QTL 316			IED	8	58,548,876	103,548,876	RGD:1599557	RGD
Q	Bp321	Blood pressure QTL 321			IED	16	819,369	3,080,748	RGD:1599557	RGD
Q	Cm52	Cardiac mass QTL 52			IAGP	1	81,342,810	225,814,178	RGD:1578520	RGD
Q	Cm53	Cardiac mass QTL 53			IAGP	9	77,171,049	105,579,863	RGD:1578520	RGD
Q	Cm63	Cardiac mass QTL 63			IED	6	1	23,802,078	RGD:1581737	RGD
Q	Cm67	Cardiac mass QTL 67			IED	2	158,146,823	182,740,242	RGD:1599557	RGD
Q	Cm68	Cardiac mass QTL 68			IED	3	27,762,470	68,832,545	RGD:1599557	RGD
Q	Cm69	Cardiac mass QTL 69			IED	10	69,555,329	71,032,765	RGD:1599557	RGD
Q	Cm70	Cardiac mass QTL 70			IED	18	6,934,443	12,677,409	RGD:1599557	RGD
S	COP/OlaHsd				IED				RGD:731241	RGD
S	F344/NHsd	F344/NHsd			QTM				RGD:69706	RGD
S	HCR/Mco	High-capacity runners			IED				RGD:2314392	RGD
S	LA/N-cp				TAS				RGD:1004	RGD
S	LEW/Cub				QTM				RGD:1303386	RGD
S	SD-Tg(Npy)400Mcwi				TAS				RGD:1357410	RGD
S	SHR.BN-(D2Rat171-D2Arb24)/Ipcv				QTM	2	116,874,922	221,284,686	RGD:619651	RGD
S	SHR.BN-(D2Rat171-D2Arb24)/Ipcv				IED	2	116,874,922	221,284,686	RGD:619651	RGD
S	SHR.BN-(D8Mit5-D8Mgh6)/Ipcv				TAS	8	32,203,394	64,762,616	RGD:619652	RGD
S	SHR.F344-(D12Mgh5-D12Mgh6)/Snk				IED	12	29,130,180	42,387,195	RGD:1599588	RGD
S	SHRSP.ZUC-(D5Rat4-D5Rat36)/IzmDmcr				IED				RGD:2300016	RGD
S	SS.LEW-(D10Arb9-D10Mco84)/Mco				IED	10	64,308,668	70,757,419	RGD:1599269	RGD
S	SS.LEW-(D10Arb9-D10Rat57)/Mco				IED	10	64,308,668	74,388,696	RGD:1599269	RGD
S	SS.LEW-(D10Mco84-D10Got93)/Mco				IED	10	70,757,255	72,827,158	RGD:1599269	RGD
S	SS.LEW-(D10Mco84-D10Mco134)/Mco				IED	10	70,757,255	70,757,419	RGD:1642602	RGD
S	SS.LEW-(D10Mco89-D10Got101)/Mco				IED	10	72,684,998	78,262,332	RGD:1599269	RGD
S	SS.LEW-(D10Mit10-D10Mgh1)/Jr				TAS	10	27,184,741	102,587,587	RGD:61040	RGD
S	SS.LEW-(D10Mit10-D10Mgh1)/Jr				QTM	10	27,184,741	102,587,587	RGD:61040	RGD
S	SS.LEW-(D10Rat29-D10Got93)/Mco				IED	10	68,842,878	72,827,158	RGD:1599269	RGD
S	SS.LEW-(D1Mco2-D1Mco35)/Jr				QTM	1	238,358,625	238,358,813	RGD:61040	RGD
S	SS.LEW-(D1Mco2-D1Mco35)/Jr				IED	1	238,358,625	238,358,813	RGD:61514	RGD
S	SS.LEW-(D5Mit9-D5Mco10)/Jr				QTM	5	62,555,131	168,174,140	RGD:61040	RGD
S	SS.MNS-(D10M11Mit119-D10Mit11)/Jr				IED	10	69,986,912	102,587,587	RGD:619626	RGD
S	SS.SHR-(D9Mco72-D9Mco105)/Mco				IED	9	44,842,118	44,842,324	RGD:6903249	RGD
S	SS.SHR-(D9Mco72-D9Mco106)/Mco				IED	9	44,842,118	44,842,324	RGD:6903249	RGD
S	SS.SHR-(D9Mco72-D9Uia4)/Mco				IED	9	44,842,118	59,247,627	RGD:6903249	RGD
S	SS.SR-(D3Mco19-D3Mco5)/Jr				IED	7 3	23,312,460 147,799,021	23,312,636 167,653,069	RGD:69705	RGD
S	SS.SR-(D3Mco19-D3Mco5)/Jr				TAS	7 3	23,312,460 147,799,021	23,312,636 167,653,069	RGD:1581650	RGD
S	SS.SR-(D3Mco36-D3Got159)/Jr				IED	3	162,807,724	171,009,778	RGD:1581650	RGD
S	SS.SR-(D3Mco36-D3Got166)/Jr				IED	3	166,484,910	171,009,778	RGD:1581650	RGD
S	SS.SR-(D3Mco36-D3Mco46)/Jr				IED	3	168,983,202	171,009,778	RGD:1581650	RGD
S	SS.SR-(D3Mco39-D3Got130)/Jr				IED	3	149,822,571	149,823,173	RGD:1581650	RGD
S	SS.SR-(D9Mco95-D9Mco98)/Mco			Induced	IED				RGD:4889902	RGD
S	WKY/Tkyo				QTM				RGD:1554311	RGD
dilated heart left ventricle
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Tnf	tumor necrosis factor			IED	20	3,661,000	3,663,618	RGD:1580213	RGD
enlarged heart
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Cm14	Cardiac mass QTL 14			QTM				RGD:69705	RGD
S	SS/Jr	Salt Sensitive			QTM				RGD:619631	RGD
S	SS/JrRkb				QTM				RGD:629621	RGD
heart hyperplasia
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	CRDH	Cohen Rosenthal Diabetic Hypertensive			IED				RGD:724741	RGD
S	NZR				TAS				RGD:1004	RGD
heart left ventricle hypertrophy
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Ednra	endothelin receptor type A			IED	19	32,042,366	32,108,153	RGD:1581830	RGD
G	Egfr	epidermal growth factor receptor			IED	14	97,617,358	97,788,211	RGD:1580955	RGD
Q	Bw26	Body weight QTL 26			IAGP	14	4,895,894	33,040,140	RGD:70849	RGD
Q	Cm10	Cardiac mass QTL 10			QTM	3	1	26,510,302	RGD:629621	RGD
Q	Cm11	Cardiac mass QTL 11			QTM	9	17,330,701	62,330,701	RGD:629621	RGD
Q	Cm12	Cardiac mass QTL 12			QTM	19	1	29,295,214	RGD:629621	RGD
Q	Cm22	Cardiac mass QTL 22			QTM	2	77,630,629	156,142,910	RGD:61484	RGD
Q	Cm23	Cardiac mass QTL 23			QTM	1	134,980,682	176,854,992	RGD:61484	RGD
Q	Cm24	Cardiac mass QTL 24			QTM	5	150,310,201	165,073,513	RGD:619659	RGD
Q	Cm25	Cardiac mass QTL 25			QTM	3	58,882,977	87,981,062	RGD:69706	RGD
Q	Cm26	Cardiac mass QTL 26			QTM	17	76,829,512	92,594,341	RGD:619658	RGD
Q	Cm27	Cardiac mass QTL 27			QTM	7	47,865,637	125,399,168	RGD:619658	RGD
Q	Cm32	Cardiac mass QTL 32			IAGP	1	103,149,923	206,567,907	RGD:1302893	RGD
Q	Cm33	Cardiac mass QTL 33			IAGP	10	56,930,545	97,589,703	RGD:1302893	RGD
Q	Cm34	Cardiac mass QTL 34			IAGP	17	9,988,620	81,039,660	RGD:1302893	RGD
Q	Cm35	Cardiac mass QTL35			IAGP	1	181,524,849	263,699,089	RGD:1302893	RGD
Q	Cm36	Cardiac mass QTL 36			IAGP	1	103,149,923	206,567,907	RGD:1302893	RGD
Q	Cm71	Cardiac mass QTL 71			IED	3	39,052,756	158,038,027	RGD:2301936	RGD
Q	Cm72	Cardiac mass QTL 72			IED	13	23,769,973	68,769,973	RGD:2301936	RGD
Q	Cm73	Cardiac mass QTL 73			IED	10	14,721,135	92,841,289	RGD:2301936	RGD
S	SHR/N				TAS				RGD:61484	RGD
S	SS.LEW-(D10Got112-Igfbp4)/Ayd				IED	10	79,857,808	87,834,315	RGD:2301185	RGD
S	SS.LEW-(D16Chm36-D16Mit2)/Ayd				IED	16	890,512	4,304,517	RGD:2301185	RGD
S	SS.LEW-(D16Rat112-D16Chm60)/Ayd				IED	16	64,718	3,165,043	RGD:2301185	RGD
S	SS.LEW-(D18Chm41-D18Rat92)/Ayd				IED	18	30,891,173	53,898,282	RGD:2301185	RGD
S	SS.LEW-(D18Rat29-D18Rat55)/Ayd				IED	18	13,904,295	54,856,651	RGD:2301185	RGD
S	SS.LEW-(D3Rat52-D3Chm57)/Ayd				IED	3	14,051,872	24,716,931	RGD:2301185	RGD
S	SS/Jr	Salt Sensitive			IED				RGD:2301185	RGD
S	SS/JrHsdMcwi				IED				RGD:727992	RGD
S	WKHA/Cfd	WKHA/Cfd			QTM				RGD:619659	RGD
S	WKHA/Edh			Model	IED				RGD:7245528	RGD
S	WKY/Cfd	WKY/Cfd			QTM				RGD:619659	RGD
heart right ventricle hypertrophy
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)			IED	9	58,327,587	58,436,057	RGD:1580077	RGD
Q	Cm15	Cardiac mass QTL 15			QTM	17	65,900,398	81,612,488	RGD:69699	RGD
increased angiogenesis
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Figf	c-fos induced growth factor			IEA	X	50,830,612	50,864,445	RGD:704404	RGD
S	F344.BN-(D3Mgh13-D3Mgh7)/Dlw				IED	3	112,319,451	112,319,585	RGD:1581610	RGD
S	SS-Chr 13^BN/Mcwi			Induced	IED				RGD:2289092	RGD
increased heart right ventricle weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	WKY/NCruk				QTM				RGD:69706	RGD
increased heart weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Nppa	natriuretic peptide A			IED	5	165,074,518	165,075,827	RGD:731210	RGD
Q	Bp163	Blood pressure QTL 163			QTM	2	66,680,022	210,636,169	RGD:68910	RGD
Q	Bp316	Blood pressure QTL 316			IED	8	58,548,876	103,548,876	RGD:1599557	RGD
Q	Bp81	Blood pressure QTL 81			QTM	3	124,893,448	171,063,335	RGD:619631	RGD
Q	Bp82	Blood pressure QTL 82			QTM	10	27,184,741	103,551,039	RGD:619631	RGD
Q	Cm1	Cardiac mass QTL 1			QTM	7	105,412,922	108,875,615	RGD:69710	RGD
Q	Cm13	Cardiac mass QTL 13			QTM	3	21,201,203	35,237,920	RGD:69705	RGD
Q	Cm16	Cardiac mass QTL 16			QTM	1	87,465,281	153,578,547	RGD:634617	RGD
Q	Cm17	Cardiac mass QTL 17			QTM	3	96,192,217	141,192,217	RGD:634617	RGD
Q	Cm18	Cardiac mass QTL 18			QTM	4	121,375,269	166,375,269	RGD:634617	RGD
Q	Cm19	Cardiac mass QTL 19			QTM	8	98,986,085	126,316,942	RGD:634617	RGD
Q	Cm20	Cardiac mass QTL 20			QTM	9	12,625,041	37,313,370	RGD:634617	RGD
Q	Cm21	Cardiac mass QTL 21			QTM	9	77,170,797	105,580,061	RGD:634617	RGD
Q	Cm29	Cardiac mass QTL 29			IAGP	2	146,228,221	232,307,864	RGD:70849	RGD
Q	Cm30	Cardiac mass QTL 30			IAGP	8	29,559,446	103,672,447	RGD:70849	RGD
Q	Cm31	Cardiac mass QTL 31			IAGP	10	29,974,190	95,369,088	RGD:70849	RGD
Q	Cm37	Cardiac mass QTL 37			IAGP	1	201,920,676	246,920,676	RGD:1334448	RGD
Q	Cm38	Cardiac mass QTL 38			IAGP	2	24,474,447	163,154,358	RGD:1303386	RGD
Q	Cm39	Cardiac mass QTL 39			IAGP	2	24,474,447	163,154,358	RGD:1303386	RGD
Q	Cm40	Cardiac mass QTL 40			IAGP	8	28,414,004	103,684,785	RGD:1303386	RGD
Q	Cm41	Cardiac mass QTL 41			IAGP	2	24,474,447	212,169,089	RGD:1303386	RGD
Q	Cm42	Cardiac mass QTL 42			IAGP	2	24,474,447	212,169,089	RGD:1303386	RGD
Q	Cm43	Cardiac mass QTL 43			IAGP	3	6,373,454	26,674,018	RGD:1554311	RGD
Q	Cm44	Cardiac mass QTL 44			IAGP	10	67,677,924	100,865,886	RGD:1554311	RGD
Q	Cm45	Cardiac mass QTL 45			IAGP	13	25,198,204	70,198,204	RGD:1554311	RGD
Q	Cm46	Cardiac mass QTL 46			IAGP	3	6,373,454	26,674,018	RGD:1554311	RGD
Q	Cm47	Cardiac mass QTL 47			IAGP	6	59,946,874	108,503,674	RGD:1554311	RGD
Q	Cm48	Cardiac mass QTL 48			IAGP	3	6,373,454	26,674,018	RGD:1554311	RGD
Q	Cm50	Cardiac mass QTL 50			QTM	10	18,217,625	53,793,117	RGD:619631	RGD
Q	Cm51	Cardiac mass QTL 51			QTM	10	53,792,967	96,584,953	RGD:619631	RGD
Q	Cm60	Cardiac mass QTL 60			IAGP	2	58,117,457	77,630,814	RGD:1580752	RGD
Q	Cm61	Cardiac mass QTL 61			IED				RGD:1581737	RGD
Q	Cm62	Cardiac mass QTL 62			IED	5	115,772,027	160,772,027	RGD:1581737	RGD
Q	Cm64	Cardiac mass QTL 64			IED	5	134,356,746	173,096,209	RGD:1581737	RGD
Q	Cm65	Cardiac mass QTL 65			IED	2	95,764,665	140,764,665	RGD:1581737	RGD
Q	Cm66	Cardiac mass QTL 66			IED	5	84,392,127	129,392,127	RGD:1581737	RGD
Q	Cm74	Cardiac mass QTL 74			IED	6	59,946,874	108,503,674	RGD:1554311	RGD
Q	Cm75	Cardiac mass QTL 75			IED	10	67,677,924	100,865,886	RGD:1554311	RGD
Q	Cm76	Cardiac mass QTL 76			IED	13	25,198,204	70,198,204	RGD:1554311	RGD
Q	Cm77	Cardiac mass QTL 77			IED	6	34,039,461	84,287,190	RGD:1554311	RGD
Q	Cm78	Cardiac mass QTL 78			IED	10	36,254,741	83,528,010	RGD:1554311	RGD
Q	Cm79	Cardiac mass QTL 79			IED	13	45,161,605	64,281,346	RGD:1554311	RGD
Q	Insul4	Insulin level QTL 4			QTM	X	134,157,190	160,699,376	RGD:619682	RGD
S	DA/OlaHsd				IED				RGD:731241	RGD
S	HTG	Prague hypertriglyceridemic			QTM				RGD:1303386	RGD
S	LCR/Mco	Low-capacity runners			IED				RGD:2314392	RGD
S	LH/Mav				TAS				RGD:1302893	RGD
S	M520				TAS				RGD:1004	RGD
S	M520/N				TAS				RGD:1004	RGD
S	SHR.ODS-Gulo^od/Shi				IED				RGD:1556471	RGD
S	SHR/OlaIpcv				QTM				RGD:619651	RGD
S	SHR/Tkyo				QTM				RGD:1554311	RGD
S	SHRSP/Tkyo				QTM				RGD:1554311	RGD
S	SS.LEW-(D10Mco84-D10Rat58)/Mco				IED	10	70,757,255	71,067,824	RGD:1642602	RGD
S	SS.LEW-(D1Rat42-D1Wox10)/Jr				IED	1	135,418,152	220,639,653	RGD:61514	RGD
S	SS.SHR-(D9Rat7-D9Rat84)/Mco				IED	9	77,172,934	83,316,504	RGD:6903249	RGD
S	SS.SHR-(D9Wox16-D9Mco73)/Mco			Induced	IED	9	18,476,042	47,764,357	RGD:2302803	RGD
S	SS/Jr	Salt Sensitive			QTM				RGD:61040	RGD
S	SS/JrHsd	Dahl Salt-Sensitive			IED				RGD:1582571	RGD
S	WKY/NCruk				QTM				RGD:69706	RGD
S	WN/N	Inbred Wistar; W/N			TAS				RGD:1004	RGD
increased left ventricle weight
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Nppa	natriuretic peptide A			IED	5	165,074,518	165,075,827	RGD:731210	RGD
S	COP.DA-(D3Rat233-D3Mgh14)/Mco				IED	3	118,863,100	118,863,223	RGD:1598978	RGD
S	LH-Chr 17^BN/Mav				IED				RGD:2290181	RGD
S	MHS/N	Milan Hypertensive Strain			TAS				RGD:1004	RGD
S	MWF-Chr 8^SHR/Rkb				IED				RGD:2312602	RGD
S	WKY/NCruk				QTM				RGD:69706	RGD
increased susceptibility to atherosclerosis
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	LA/NJcr-cp	JCR:LA-corpulent rat			IED				RGD:1642391	RGD
S	SS-Tg(ApoC3-CETP)53Opaz				IED				RGD:2290427	RGD
kidney vascular congestion
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	SS				TAS				RGD:1004	RGD
pathological neovascularization
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Epha2	Eph receptor A2			IED	5	160,185,143	160,214,727	RGD:1580975	RGD
G	Kdr	kinase insert domain receptor			IED				RGD:2292014	RGD
thick ventricular wall
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	SS-Chr 12^BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi				IED				RGD:7204442	RGD
varicose veins
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	W/Gaox				IED				RGD:2298497	RGD
vascular smooth muscle cell hyperplasia
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
Q	Smcn1	Smooth muscle cell number QTL 1			IAGP	2	59,507,966	131,522,430	RGD:1357419	RGD
Q	Vnigr3	Vascular neointimal growth QTL 3			IED	3	132,947,812	171,063,335	RGD:2316923	RGD
S	SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco				IED				RGD:2316923	RGD
S	SHR.BN-(D3Rat159-D3Rat1)/Mco				IED	3	119,437,175	170,016,653	RGD:2316923	RGD
S	SHR.BN-(D6Rat40-D6Rat170)/Mco				IED	6	1,301,952	46,792,623	RGD:2316923	RGD
vascular smooth muscle hypertrophy
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Pld2	phospholipase D2			IED	10	57,388,474	57,439,063	RGD:1642674	RGD
G	Prkcz	protein kinase C, zeta			IED	5	172,061,825	172,172,793	RGD:1642674	RGD
ventricular hypoplasia
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
S	SHRSP-Tg(Tagln-ACE2)6918Bdr				IED				RGD:2302131	RGD

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	6280
cardiovascular system phenotype	1323
abnormal cardiovascular system morphology	258
abnormal blood vessel morphology +	53
abnormal cardiovascular development +	10
abnormal heart morphology +	205
aneurysm +	0